Translational Neuroscience and Technology Lab
(TRANSiT Lab)
(TRANSiT Lab)
VISION AND MISSION
Our vision is to use information from our brain, body and behavior, for revolutionizing neuro-medicine and bring in more intelligence into clinical practice, especially by suggesting personalized and precise therapeutic dynamics in terms of kind of treatment and management, and their strategy such as therapeutic target and their timing.
Our mission is to use the principles of computational cognitive neuroscience and machine learning, neural engineering and technology to build neurological and psychiatry relevant applications.
1. Cognitive Load, Fatigue, and Vigilance
Psychometric, Qualitative and objective, gamified assessments
Detection and prediction of microsleep using:
Cognitive load markers
EEG and physiological signals
Facial dynamics and behavioral cues
Applications in safety-critical environments (railways, ICU, law, dementia)
2. Closed-Loop Cognitive Dynamics
Modeling cognition as a dynamical system
Closed-loop intervention frameworks using:
Electrophysiology
Behavioral feedback (game based)
Multimodal bio-signals
Real-time prediction → intervention → adaptation pipelines
3. Brain–Body–Gut Coupling
Cognitive electrophysiology across brain, body, and gut
Gut-brain oscillations and traveling waves
Microbiome-linked cognition and behavior
Cross-cultural and personality-based cognitive variability
4. Cognitive Control, Decision-Making, and Bias
Inhibitory control, stopping vs accept–reject decisions
Cognitive bias, logical inconsistency, and failure modes
Computational and causal models of decision reliability
5. Cognitive Interfaces and Neurotechnology
Brain–Computer Interfaces (BCI)
Avatar-based, AR/VR, and AI-driven cognitive interfaces
Non-invasive stimulation and entrainment systems
A. Mental Health & Psychiatry
Depression: early prediction of treatment response (≤10 days)
Bipolar disorder: mood swing prediction via behavior and games
Autism: predictive and immersive interfaces for social cognition
Tele-counseling platforms with biofeedback and avatars
B. Neurological Disorders
Parkinson’s disease:
Medication optimization
Non-invasive stimulation modeling
Gut-brain electrophysiology
Alzheimer’s & MCI:
Mental overload markers
AR-assisted memory support
Epilepsy:
Cognitive dynamics for seizure prediction
C. Safety-Critical Human Performance
Indian Railways (Loco Pilots):
Microsleep detection and prediction
Cognitive load and vigilance monitoring
Real-time mitigation strategies
ICU & Critical Care:
EEG-based coma state classification
Comatose/Consciousness assessment beyond traditional scales
D. Law, Ethics, and High-Stakes Decision Systems
Auditing Legal LLMs for:
Cognitive bias
Logical inconsistency
Silent failure modes
Causal ablation and adversarial robustness metrics
Mathematical quantification of reasoning reliability
E. Rehabilitation and Assistive Technologies
Stroke rehabilitation using multimodal cues
Tremor suppression via brain entrainment
Motor coordination via adaptive BCIs
Mental health kiosks and assessment interfaces
Personalized treatment-response prediction systems
Cognitive load monitoring dashboards
AI-AR immersive training environments
Closed-loop clinical decision support tools
Check our entrepreneurial wing website: Neuroclinical Innovative Solutions Pvt. Ltd.
Translation of lab research into deployable clinical and field-ready systems
Development of kiosks, decision-support tools, and AI platforms
Partnerships with hospitals, NGOs, and public-sector stakeholders
You can read about our earlier work here.
You can know more about our research through our scientific papers.
We are sharing our resources. You can explore our codes and softwares from this link.
We have more things to share! please find here our popular science blogs in English, Tamil. Some of them are insights gathered from our popular science club for behavioral insights, translation, and service (popscicle bites)
We venture into arts for portraying our science, one primer can be found here (thanks to our collaborators- Gowdham and team!)
To know more about a recent workshop we organized at the Annual Conference on Cognitive Science, Kanpur, December-'23 Here
We recently organizes a workshop on whole person research using EEG, EGG and ECG this December at IIT Bombay. Participate, More details here
We also showcased our applications in Samanvay 2024. Details here. Looking forward to chatting with Industry.
Courses offered at IIT Kanpur
2022-23
CGS641: Topics in Translational Neuroscience
CGS613: Basics of Electroencephalography
2023-24
CGS600: Computational Tools for Cognitive Science
CGS786: Computational Cognitive Science
CGS613: Basics of Electroencephalography
2024-25
CGS641: Topics in Translational Neuroscience
CGS616: Human Centered Computing
CGS613m: Basics of Electroencephalography
If you are interested to work and collaborate with us on our mission,
If you are interested to assist us on research projects as an undergraduate, graduate or a postdoc, We are building a highly interdisciplinary team and have multiple openings
- Please leave us a message stating your interest to discuss the ongoing projects!
CODE OF CONDUCT
We pledge that despite the diversity in our interests and ways to pursue scientific research and developing technology, we will adhere to research integrity and keep our values, ethics, rigor, relevance, transparency, respect, impartiality, and accountability. We will conduct our research in a systematic and methodologically rigorous fashion and carefully draw conclusions that can be traced to the research.
We will maintain good documentation in the form of laboratory notes, research journals, or field notes for keeping track of our research progress. This record of the processes and procedures, including information on data sources, their quality, storage, and retrieval, is necessary to document proper research practice and address the veracity of results.
We will secure participant consent and all requisite permissions for research. We will store research data and related files securely during all phases of the research process. We will ensure clear data ownership and accountability, access restrictions with appropriate protocols to ensure safety and privacy, data integrity by using a copy of the original data, regular back-ups, and careful and reliable data collection, storage, and retrieval.
It is our responsibility to avoid plagiarism, falsification, fabrication, or misrepresentation and to report such misdemeanors if they are observed or suspected.
To minimize the potential for any conflicts, agreements regarding roles and responsibilities, authorship, ownership of intellectual property, and other arrangements, especially in collaborative research, will be clarified at the outset.
(Adapted from University Grants Commission Guidance Document on Good Academic Research Practices, Sept. 2020)
If You Wish to FUND and support Our Research & Translational Activities, please get in touch!
Share Your Thoughts!
Dr. Pragathi Priyadharsini Balasubramani - Principal Investigator
Lab Address: Rooms 524 and 527, Department of Cognitive Science
Engineering Science Building-2 (ESB-2)- 4th floor
Indian Institute of Technology (IIT) Kanpur, Kanpur 208016
Email here
To contact our entrepreneurial wing, please visit the website- https://neuroinnovativesolutions.com/