業績
業績
2025年
Defective repair of G1-phase double-strand breaks in WRNIP1/Ku70 double knockout cells.
Yoshimura A, Abe T, Seki M
Biol Pharm Bull. In press
Automatic classification of human chromosome shapes using convolutional neural network models
Matsumoto S, Ikemoto D, Abe T, Okubo K, Nishikawa K.
IEICE TRANS. ELECTRON.; In press
A hypothesis for nucleosome evolution based on mutational analysis.
Nakabayashi Y, Seki M.
Genes Genet Syst.;100. 2025
TIPIN is essential for chromosome stability and cell viability in BRCA1-deficient cells. Abe T, Yoshimoto Y, Matsuno S, Yoshimura A, Hirota K, Seki M.
Biochem Biophys Res Commun.; 752:151467. 2025
Monoclonal antibody generation by controlled immunoglobulin gene rearrangements.
Murayama A, Matsui S, Abe T, Kanemaki MT, Kurosawa K, Hirota K, Ohta K, Seo H.
Commun Biol.; 8:283. 2025
2024年
The Possible Crystallization Process in the Origin of Bacteria, Archaea, Viruses, and Mobile Elements.
Yoshimura A, Seki M.
Biology (Basel).; 14:3. 2024
Theoretical Framework for Novel Catalytic Biomolecules Composed of Multiple Peptides.
Ambo A, Ohno S, Yamaguchi Y, Seki M.
Chem Pharm Bull (Tokyo). ;72:804-809. 2024
Sex chromosome cycle as a mechanism of stable sex determination.
Hayashi S, Abe T, Igawa T, Katsura Y, Kazama Y, Nozawa M.
J Biochem.; 176:81-95. 2024
2023年
Application of neural network-based image analysis to detect sister chromatid cohesion defects.
Ikemoto D, Taniguchi T, Hirota K, Nishikawa K, Okubo K, Abe T.
Sci Rep. ;13:2133, 2023
PCNA recruits cohesin loader Scc2/NIPBL to ensure sister chromatid cohesion.
Psakhye I, Kawasumi R, Abe T, Hirota K and Branzei D.
Nat. Struct. Mol. Biol. ; 30, 1286–1294, 2023
The proofreading exonuclease of leading-strand DNA polymerase epsilon prevents replication fork collapse at broken template strands.
Ahmad T, Kawasumi R, Taniguchi T, Abe T, Terada K, Tsuda M, Shimizu N, Tsurimoto T, Takeda S, Hirota K.
Nucleic Acids Res. ; 51:12288-12302, 2023
Functional Analyses of an Evolutionarily Conserved Acidic Patch on the Nucleosome.
Nakabayashi Y, Seki M.
Biol Pharm Bull. ;46:1619-1624. 2023
The first chick brain with non-invasively embedded beads: a foundation for the automation of brain research
Yoshimura A, Seki M.
Bulletin of the National Research Centre ; 47:56. 2023
On the origin of the genetic code.
Seki M.
Genes Genet Syst. ;98:9-24. 2023
2022年
Functional Domain Mapping of Werner Interacting Protein 1 (WRNIP1).
Yoshimura A, Sakakihara T, Enomoto T, Seki M.
Biol Pharm Bull.; 45:200-206. 2022
Transcription destabilizes centromere function.
Nakabayashi Y, Seki M.
Biochem Biophys Res Commun. ;586:150-156. 2022
2021年
Division of labor of Y-family polymerases in translesion-DNA synthesis for distinct types of DNA damage.
Inomata Y, Abe T, Tsuda M, Takeda S, Hirota K.
PLoS One. ;16:e0252587, 2021
Pold4, the fourth subunit of replicative polymerase δ, suppresses gene conversion in the immunoglobulin-variable gene in avian DT40 cells.
Kojima K, Ooka M, Abe T, Hirota K.
DNA Repair (Amst). ;100:103056, 2021
Vertebrate CTF18 and DDX11 essential function in cohesion is bypassed by preventing WAPL-mediated cohesin release.
Kawasumi R*, Abe T*, Psakhye I, Miyata K, Hirota K, Branzei D.
Genes Dev. ;35:1368-1382. 2021
Targeting chromosome trisomy for chromosome editing.
Abe T, Suzuki Y, Ikeya T, Hirota K.
Sci Rep. ;11:18054, 2021
Reciprocal stabilization of transcription factor binding integrates two signaling pathways to regulate fission yeast fbp1 transcription.
Koda W, Senmatsu S, Abe T, Hoffman CS, Hirota K.
Nucleic Acids Res. ;49:9809-9820, 2021
PRDX1 is essential for the viability and maintenance of reactive oxygen species in chicken DT40.
Moriwaki T, Yoshimura A, Tamari Y, Sasanuma H, Takeda S, Seki M, Tano K.
Genes Environ.; 43:35. 2021
Analysis of the molecular evolution of histone variant H2A.Z using a linker-mediated complex strategy and yeast genetic complementation.
Kitagawa S, Kusakabe M, Takahashi D, Narimiya T, Nakabayashi Y, Seki M, Horigome C, Harata M.
Biosci Biotechnol Biochem. ;86:104-108. 2021
2020年以前 (主要論文のみ)
An improved functional analysis of linker-mediated complex (iFALC) strategy.
Nakabayashi Y, Harata M, Seki M.
Biochem Biophys Res Commun. ;526:1164-1169. 2020
AND-1 fork protection function prevents fork resection and is essential for proliferation.
Abe T, Kawasumi R, Giannattasio M, Dusi S, Yoshimoto Y, Miyata K, Umemura K, Hirota K, Branzei D.
Nat Commun. ;9:3091, 2018
Warsaw breakage syndrome DDX11 helicase acts jointly with RAD17 in the repair of bulky lesions and replication through abasic sites.
Abe T, Ooka M, Kawasumi R, Miyata K, Takata M, Hirota K, Branzei D.
Proc Natl Acad Sci U S A. ;115:8412-8417, 2018
ESCO1/2's roles in chromosome structure and interphase chromatin organization.
Kawasumi R*, Abe T*, Arakawa H, Garre M, Hirota K, Branzei D.
Genes Dev. ; 31:2136-2150, 2017
Roles of common subunits within distinct multisubunit complexes.
Nakabayashi Y, Kawashima S, Enomoto T, Seki M, Horikoshi M.
Proc Natl Acad Sci U S A.; 111:699-704. 2014
Tipin functions in the protection against topoisomerase I inhibitor.
Hosono Y*, Abe T*, Higuchi M*, Kajii K, Sakuraba S, Tada S, Enomoto T, Seki M.
J Biol Chem.; 289 :11374-84, 2014
WRNIP1 functions upstream of DNA polymerase eta in the UV-induced DNA damage response.
Yoshimura A, Kobayashi Y, Tada S, Seki M, Enomoto T.
Biochem Biophys Res Commun.; ;452:48-52. 2014
Global analysis of core histones reveals nucleosomal surfaces required for chromosome bi-orientation.
Kawashima S, Nakabayashi Y, Matsubara K, Sano N, Enomoto T, Tanaka K, Seki M, Horikoshi M.
EMBO J.; 30:3353-67. 2011
The histone chaperone facilitates chromatin transcription (FACT) protein maintains normal replication fork rates.
Abe T, Sugimura K, Hosono Y, Takami Y, Akita M, Yoshimura A, Tada S, Nakayama T, Murofushi H, Okumura K, Takeda S, Horikoshi M, Seki M, Enomoto T.
J Biol Chem.; 286:30504-12, 2011