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Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway.
Nature Cancer 4:419-435 (Cover selected)
Authors: Woo-Yong Park, Justin M. Gray, ... and Li Yang.
Publication date: March 2023
1. Abdul Ahad, Feng Leng, Hiroshi Ichise, Edward Schrom, Jae Young So, Carter Sellner, Yang Gu, Wenjuan Wang, Celine Kieu, Woo-Yong Park, ... and Li Yang. Immune Niche Formation in Engineered Mouse Models Reveals Mechanisms of Tumor Dormancy. Biorxiv, 2025, doi: https://doi.org/10.1101/2025.04.16.649000
2. Justin M. Gray*, Woo-Yong Park*#, Ronald J. Holewinski, … and Li Yang#. (2025). Proteomic analysis of tumor cell nuclear expulsion reveals significant cell adhesion and RNA binding programs in extracellular chromatin. Scientific Reports. 15, 28504. *: Equal contribution. #: co-corresponding author.
3. Sara Zahraeifard*, ZG Xiao*, Jae Young So*, Abdul Ahad, Selina Montoya, Woo-Yong Park, … and Li Yang. (2024). Loss of tumor suppressors promotes a non-cell-autonomous inflammatory tumor microenvironment and enhances LAG3+T cell mediated immune suppression. Nature Communications. 15:5873. *: Equal contribution.
4. Woo-Yong Park*, Justin M. Gray*, Ronald Holewinski, … and Li Yang. (2023). Apoptosis-induced nuclear expulsion in tumor cells drives S100a4-mediated metastatic outgrowth through the RAGE pathway. Nature Cancer (cover selected), 4:419–435. *: Equal contribution.
5. Jae-Young So, Howard H. Yang, Woo-Yong Park, … and Li Yang. (2022). DNA methyltransferase 3B–mediated intratumoral heterogeneity and therapeutic targeting in breast cancer recurrence and metastasis. Molecular Cancer Research, 20(11):1674–1685.
6. Hiroki Ishii, Woo-Yong Park, JaeYoung So, …, and Li Yang. (2020). Loss of myeloid‐specific lamin A/C drives lung metastasis through Gfi‐1 and C/EBPε‐mediated granulocytic differentiation. Molecular Carcinogenesis, 59(7):679-690.
7. Beom-Jin Hong*, Woo-Yong Park*, Hwa-Ryeon Kim, … and Mi-Young Kim. (2019). Oncogenic KRAS sensitizes lung adenocarcinoma to GSK-J4-induced metabolic and oxidative stress. Cancer Research, 79:5849–59. *: Equal contribution.
8. Woo-Yong Park, Beom-Jin Hong, … and Mi-Young Kim. (2016). H3K27 demethylase JMJD3 employs the NF-κB and BMP signaling pathways to modulate the tumor microenvironment and promote melanoma progression and metastasis. Cancer Research, 76(1):161-170.
9. Jeong-Hyun Ryou, Yoo-Kyoung Sohn, Da-Eun Hwang, Woo-Yong Park, … and Hak-Sung Kim. (2016). Engineering of bacterial exotoxins for highly efficient and receptor-specific intracellular delivery of diverse cargos. Biotechnol Bioeng, 113(8):1639-46.