Publications

Cellular survivorship bias as a mechanistic driver of muscle stem cell aging. 

Kang J†, Benjamin DI†, Guo Q, Evangelista C, Kim S, Arjona M, Both P, Chung M, Krishnan AK, Dhaliwal G, Lam R, Rando TA. 

Science. 2026 Jan; 391(6784):517-521. doi: 10.1126/science.ads9175. 

Novel respiratory disease diagnosis tool: development of an Au-ReS2-functionalized extended-gate field-effect transistor-type aptasensor for simultaneous detection of granzyme B and perforin.

Jung S, Ju M, Park H, Kang S, Kim J, Seo Y, Kang J, Jang JG, Choi JH, Kim DH, Park C, Lee MH, Lee W, Lee T.

Small Sci. 2026 Jan; 6(1):e202500485. doi: 10.1002/smsc.202500485.

Harnessing deaminated DNA to modulate mRNA translation for controlled and sequential protein expression.

Choi J, Jeong TU, Cabanting F, Song Jm Park C, Hwang S, Kang JY, Kang J, Fang L, Jun YW.

Angew Chem Int Ed Engl. 2025 Nov; e16389. doi: 10.1002/anie.202516389. 

Benchmarking cell type and gene set annotation by large language model with AnnDictionary.

Tabula Sapiens Consortium (Kang J)

Nature Communications. 2025 Oct; 16(1): 9511. doi: 10.1038/s41467-025-64511-x. 

In vivo self-renewal and expansion of quiescent stem cells from a non-human primate.

Kang J, Kanugovi A, Stella MPJ, Frimand Z, Farup J, Urtasun A, Liu S, Clausen AS, Ishak H, Bui S, Kim S, Ezran C, Botvinnik O, Porpiglia E, Krasnow M, de Morree A, Rando TA.

Nature Communications. 2025 Jun; 16(1):5370. doi: 10.1038/s41467-025-58897-x.

Protocol for quantifying muscle fiber size, number, and central nucleation of mouse skeletal muscle cross-sections using Myotally software.

Both P, Kim S, Kang J, Arjona M, Benjamin DI, Nutter CW, Goshayeshi A, Rando TA. 

Star Protocols. 2025 Jan; 6(1). doi: 10.1016/j.xpro.2024.103555.

An organism-wide atlas of hormonal signaling based on the mouse lemur single-cell transcriptome. 

Tabula Microcebus Consortium (Kang J)

Nature Communications. 2024 Mar;15(1):2188. doi: 10.1038/s41467-024-46070-9.

Depletion of SAM leading to loss of heterochromatin drives muscle stem cell ageing. 

Kang J, Benjamin DI, Kim S, Salvi JS, Dhaliwal G, Lam R, Goshayeshi A, Brett JO, Liu L, Rando TA. 

Nature Metabolism. 2024 Jan; 6(1):153-168. doi: 10.1038/s42255-023-00955-z. 

Exercise reprograms the inflammatory landscape of multiple stem cell compartments during mammalian aging. 

Liu L, Kim S, Buckley MT, Reyes JM, Kang J, Tian L, Wang M, Lieu A, Mao M, Rodriguez C, Ishak HL, Jeong M, Wu JC, Goodell MA, Brunet A, Rando TA. 

Cell Stem Cell. 2023 May; 30(5):689-705.e4. doi: 10.1016/j.stem.2023.03.016. 

Multiomics reveals glutathione metabolism as a driver of bimodality during stem cell aging. 

Benjamin DI, Brett JO, Both P, Benjamin JS, Ishak HL, Kang J, Kim S, Chung M, Arjona M, Nutter CW, Tan JH, Krishnan AK, Dulay H, Louie SM, de Morree A, Nomura DK, Rando TA. 

Cell Metabolism. 2023 Mar; 35(3):472-486. doi: 10.1016/j.cmet.2023.02.001.

Fasting induces a highly resilient deep quiescent state in muscle stem cells via ketone body signaling. 

Benjamin DI, Both P, Benjamin JS, Nutter CW, Tan JH, Kang J, Machado LA, Klein JDD, de Morree A, Kim S, Liu L, Dulay H, Feraboli L, Louie SM, Nomura DK, Rando TA. 

Cell Metabolism. 2022 Jun; 34(6):902-918.e6. doi: 10.1016/j.cmet.2022.04.012. 

Adversarial domain translation networks for integrating large-scale atlas-level single-cell datasets. 

Tabula Microcebus Consortium (Kang J)

Nature Computational Science. 2022 May; 2(5):317-330. doi: 10.1038/s43588-022-00251-y.

ATR activity controls stem cell quiescence via the cyclin F-SCF complex. 

Salvi JS, Kang J, Kim S, Colville AJ, de Morrée A, Billeskov TB, Larsen MC, Kanugovi A, van Velthoven CTJ, Cimprich KA, Rando TA. 

Proc Natl Acad Sci U S A. 2022 May 3;119(18):e2115638119. doi: 10.1073/pnas.2115638119.

Ketohexokinase-A acts as a nuclear protein kinase that mediates fructose-induced metastasis in breast cancer. 

Kim J†, Kang J†, Kang Y, Woo J, Kim Y, Huh J, Park JW. 

Nature Communications. 2020 Oct; 11(1):5436. doi: 10.1038/s41467-020-19263-1.

Aberrant expression of CITED2 promotes prostate cancer metastasis by activating the nucleolin-AKT pathway. 

Shin SH, Lee GY, Lee M, Kang J, Shin HW, Chun YS, Park JW. 

Nature Communications. 2018 Oct; 9(1):4113. doi: 10.1038/s41467-018-06606-2.

FIH permits NAA10 to catalyze the oxygen-dependent lysyl-acetylation of HIF-1α. 

Kang J, Chun YS, Huh J, Park JW. 

Redox Biology. 2018 Oct; 364-374. doi: 10.1016/j.redox.2018.09.002.

Ferritin heavy chain controls the HIF-driven hypoxic response by activating the asparaginyl hydroxylase FIH. 

Jin P, Kang J, Lee MK, Park JW. 

Biochem Biophys Res Commun. 2018 May; 499(3):475-481. doi: 10.1016/j.bbrc.2018.03.173.

A novel HIF1AN substrate KANK3 plays a tumor-suppressive role in hepatocellular carcinoma. 

Kim I, Kang J, Gee HY, Park JW. 

Cell Biol Int. 2018 Mar; 42(3):303-312. doi: 10.1002/cbin.10895. 

The F-box protein FBXO7 positively regulates bone morphogenetic protein-mediated signaling through Lys-63-specific ubiquitination of neurotrophin receptor-interacting MAGE (NRAGE). 

Kang J, Chung KC. 

Cell Mol Life Sci. 2015 Jan;72(1):181-95. doi: 10.1007/s00018-014-1665-5.