Research Themes

Research Goal & Perspective

Nanostructure-enabled active manipulation and optical transduction of nanoscale biological and chemical phenomena
Our research is grounded in the principles of electrical engineering and optics, focusing on the development of scientific sensing technologies and platform systems applicable to biosensors, biomedical devices, and the elucidation of disease mechanisms.
Rather than pursuing purely theoretical or simulation-based studies, our lab emphasizes experimental, physics- and materials science-based approaches rooted in electrical engineering. Through hands-on research, we aim to understand the underlying principles of physical phenomena and translate these insights into meaningful, real-world applications.
Positioned at the core of what is often referred to as "convergent science," our work lies at the intersection of physics, electrical/materials/mechanical engineering, and biotechnology. We pursue research themes that allow scientists trained in electrical engineering to contribute practically and substantively to real-world problems, going beyond theoretical discourse to deliver impactful innovations.
Our research laboratory has a clear and ambitious mission:
To leverage scientific expertise to create solutions that benefit humanity—while achieving world-leading, first-of-its-kind performance in our technologies. We are committed to providing an exceptional research environment and strive to assemble a top-tier talent pool to drive innovation at the highest level.

전기공학 전공을 기반으로 센서칩 개발 및 소자 제작을 위한 MEMS/NEMS, 바이오메디컬, 의공학, 전기·광학 융합 연구 수행
전기공학적 접근을 바탕으로 바이오센서, 바이오의학, 질병 메커니즘 규명에 활용 가능한 과학적 센싱 기술 및 플랫폼 개발에 주력
이론 물리·시뮬레이션 중심 연구가 아닌, 물리·재료·전기공학 기반의 실험 중심 연구를 통해 현상의 원리를 규명하고 결론 도출
연구 결과가 실제 생활과 사회에 갖는 의미와 활용 가능성을 중시하는 응용·실증 중심 연구 지향
물리학, 전기·재료·기계공학, 생명공학이 만나는 융합 연구를 통해 폭넓은 연구 경험 제공
전공 배경에 상관없이, 물리적 사고와 실험에 대한 호기심을 가진 학생을 환영
인류에 실질적으로 기여할 수 있는 연구 주제를 대상으로 세계 최초·최고 수준의 성능 달성을 목표로 연구 수행
최상의 연구 환경과 최고의 연구 인력 구성을 지향하는 연구실

Bio Application. 인공세포막 재현 (Reconstruction of Lipid model membrane)

During vesicular trafficking and release of enveloped viruses, the budding and fission processes dynamically remodel the donor cell membrane in a protein- or a lipid-mediated manner. In all cases, in addition to the generation or relief of the curvature stress, the buds recruit specific lipids and proteins from the donor membrane through restricted diffusion for the development of a ring-type raft domain of closed topology. Here, by reconstituting the bud topography in a model membrane, we demonstrate the preferential localization of cholesterol- and sphingomyelin-enriched microdomains in the collar band of the bud-neck interfaced with the donor membrane. The geometrical approach to the recapitulation of the dynamic membrane reorganization, resulting from the local radii of curvatures from nanometre-to-micrometre scales, offers important clues for understanding the active roles of the bud topography in the sorting and migration machinery of key signalling proteins involved in membrane budding.

인간의 세포는 유전물질을 보호하고, 세포 내외로 신호 전달을 용이하게 하기 위하여, 세포막에 의해 둘러쌓여 있습니다. 실제 세포막을 그대로 체외로 가지고 와서 재현함에 큰 어려움이 있기 때문에, 인공 세포막을 재현함으로써, 체내에서 발생하는 세포막의 역할, 관련 질병과의 연관성 등등의 세포막 관점에서의 바이오 현상을 물리학적 관점에서 설명하고 있습니다.
타겟질병: 치매단백질의 세포막과의 질병 유발인자 규명, 엑소좀을 이용한 각종 질병질환 연구.
관련 학문: 생명공학, 생물 물리학, 화학공학, 전기공학, 재료공학, 생물학

Related Research Project:
Identification of Alzheimer’s Disease Risk Factors through the Analysis of Protein Binding and Behavior on the Cell Membrane

In order to identify the causative factors of Alzheimer’s disease, it is essential to obtain precise information on the lipid membrane domains known as lipid rafts, as well as to accurately characterize the proteins that associate with these domains.
Through such investigations, we aim to study the attachment and behavior of Alzheimer’s-related proteins on the cell membrane.
This research seeks to uncover the underlying factors contributing to the onset of Alzheimer’s disease and to develop a sensor platform that can ultimately be applied to both the qualitative and quantitative detection of protein binding and drug interactions

광학 센서 개발 (Development of Optical sensor platform)

We are conducting sensor development from the perspective of electrical engineering-based optical physics, electronic physics, and optics.
Our research explores various approaches, such as placing cell membranes onto optical sensors and culturing living cells directly on sensor platforms, in order to reproduce and observe phenomena that closely resemble in vivo conditions.
Based on the principles derived from these observations, we aim to develop practical optical biosensors that can be applied in real-world biomedical applications.
Research Title:
Detection and Quantification of Biomolecules in the Visible, Raman, and Terahertz Regions through the Control of Nanostructures
Related Disciplines:
Electronic Physics, Biophysics, Chemistry, Electrical Engineering, Materials Science, Biology, Physics, Optics

Nano Application : Nanosacle-particle concentration/separation

On going process : Bio + Optics

Related Research Project

Development of a Molecular-Based High-Concentration Real-Time Biosensing Platform for Early Detection

We are conducting research on the essential processes of nanoparticle enrichment, collection, and purification for nanoscale sensing applications.
Building upon nanogap technology developed during postdoctoral research, we are adapting and optimizing this technique for use in biosensing platforms.
Our work focuses on the collection and purification of ultra-fine nanoparticles from both gaseous and liquid phases.
Related Research Areas:
Microplastic detection, cancer biomarker analysis, exosome isolation, fungal particle detection, and nanoparticle purification/removal technologies
Relevant Disciplines:
Electronic Physics, Biophysics, Chemistry, Electrical Engineering, Materials Science, Mechanical Engineering, Biology, Physics, Optics

나노 입자 센싱을 위해 필수적으로 진행되는, 나노물질 고농축화 및 포집, 정제에 관련된 연구를 진행하고 있습니다.박사 후 연구원 과정시, 체득한 나노갭 기술을 바이오 센서에 적합하게 변형하여 나노물질 고농축화 및 포집, 정제 기술을 진행하고 있습니다. 초미세크기의 극나노입자를 기상/액상에 포집하는 연구를 진행
관련연구: 미세플라스틱/암진단마커/엑소좀/균류/나노입자 정제/제거 기술 확립
관련 학문: 전자물리, 생물 물리학, 화학, 전기공학, 재료공학, 기계공학, 생물학, 물리학, 광학

We are currently conducting advanced research on the development of substrates capable of concentrating and positioning ultra-small molecular aggregates and nanoparticles in the 20–200 nm size range.
By integrating these substrates with light-focusing metasurfaces, we aim to enable simultaneous molecular enrichment and real-time detection of molecular fingerprints.

Optics Application. 나노구조체 기반 광학센서 (Nanophotonic devices)

자기조립 나노 구조체 및 나노멤스 기술을 이용하여, 가시광선 영역내에서 색을 발하는 센서 플랫폼을 개발하여, 추가적으로 환경에 민감한 센서 플랫폼을 통해 현장대응성 환경 감지 센서를 개발하고 있습니다.
관련연구: 기체/액체/바이오물질 센서 개발
관련 학문: 전기공학, 재료공학, 물리학, 광학

Related Research Project

Metal-Dielectric-Metal 구조를 통한 수소 누출 검지용 광디스플레이 장치 개발

수소가 닿는 경우, 메탈의 하이드라이드 현상이 광학적인 물리적 변수를 변화시키게 되는 원리를 이용하여, 수소에 민감하게 반응하는 소자를 개발하는 연구를 진행중.

대면적, 저비용, 고민감도, 반복성, 지속성, 생산성을 모두 고려하여 상업화가 가능한 수준으로 연구방향을 잡고 수소분자에 대한 민감도를 가지는 나노구조물 기반 대면적 디스플레이를 구현하는 것을 목표

Chip Fabrication using MEMS/NEMS

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