GROUP LEADER – Ana O’Loghlen
My main scientific interest relies on understanding how the cellular phenotype, senescence, is regulated. My interest in senescence started during my postdoc position at the MRC in London in the team of Jesus Gil, after a short postdoc at the Spanish National Cancer Centre (CNIO) with Angel Nebreda. I later briefly joined Gordon Peters lab at the London Research Institute before staring my own lab in October 2013 at Queen Mary University of London.
PhD STUDENT – Michela Borghesan
I was born in Palermo (Italy). I obtained my Master in Cellular and Molecular Biology in 2011 from the Faculty of Sciences, University of Palermo, Italy. I developed my interest for epigenetics during my time as visiting trainee at The Foundation for Liver Research, London in 2012. In 2013 I obtained a fellowship from AIRC (Italian Association for Cancer Research) to work within Dr. Manlio Vinciguerra’s Lab at the Institute for Liver and Digestive Health-UCL-Royal Free Hospital, London. This work investigated the role of Histone variants in senescence associated with hepatocellular carcinoma and other liver diseases. In October 2015, I joined Dr. Ana O’Loghlen’s Lab as PhD student thanks to the MRC fellowhip.
POST DOC - Paula Carpintero
Paula obtained her degree in Biology in 2011 and her Master’s Degree in 2012. She was working as a PhD student (2012-2015) at the Rheumatology division at INIBIC (A Coruña, Spain) in the group leaded by Dr. María D. Mayán studying the cell-to-cell communication in the articular cartilage and its implication with the development of osteoarthritis. She was awarded with a 3-months fellowship from Fundación Barrié (A Coruña) to visit the proteomic facility at Yale University (CT, USA). She is the co-author of 4 reserach articles and inventor of an international patent (PCT, USA). In April 2015 she continue as a postdoctoral researcher in the group leaded by Dr. María D. Mayán studying the role of connexins and pannexin in skin cancer development. She is member of the Spanish Rheumatology Society (SER), Spanish Biochemical and Molecular Biology Society (SEBBM) and of the Spanish Proteomics Society (SeProt).
POST DOC - Juan Fafian Labora
Juan was born in A Coruña. He obtained her degree in Chemistry in 2012 from University of Santiago de Compostela, Spain and her Master’s degree in Biomedical Research in 2013 from University of A Coruña, Spain. In 2016, he obtained his PhD in 2016, on the study of influence ageing on proliferation, pluripotency and immunogenic profiles from bone marrow mesenchymal stem cells, supervised by Professor Maria C. Arufe in Cellular Therapy and Regenerative Medicine Research Group, University of A Coruña, Spain. During his PhD, he got an EMBO Short –term fellowship grant to work about influence ageing on pro-inflammatory miRNA profile contained in mesenchymal stem cell-derived extracellular vesicles, in Professor Fons Van de Loo’s group at Radboud University in Nijmegen, The Netherlands. He joined in Epigenetic Cellular and Senescence Group at University Queen Mary, London in January 2017.
POST DOC - Olga Eleftheriadou
I obtained my degree in Biological Applications and Technologies from the University of Ioannina (Greece) in 2011. I was working as a research scientist in 2012-2013 at Kingston University London, in the group led by Professor Edith Sim and Dr Ali Ryan, to investigate the mycobacterial enzyme HsaD as a potential anti-tubercular target using fragment-based drug design approaches. Then, I received a British Heart Foundation PhD studentship to study the role of type 2A serine/threonine protein phosphatases and alpha4 regulatory protein in cardiac health and hypertrophy, under the supervision of Dr Andrew K Snabaitis, at the School of Life Sciences, Pharmacy and Chemistry, Kingston University London, and completed my PhD in 2017. I have published in peer-reviewed journals, and I am also a member of the British Pharmacological Society and British Society for Cardiovascular Research.
PhD student - Farzana Begum
I studied Biomedical Sciences at Queen Mary University as my undergraduate degree and quickly developed an interest in epigenetics and immunology. Here I carried out my first research project investigating relationships between the environment and host immune responses. I explored this interest further by studying a Masters in Infection and Immunity (University College London), where I carried out a collaborative research project in the Towers Lab (UCL) and Qasim Lab (Institute of Child Health, Great Ormand Street Hospital). Here, I used CRISPR/Cas9 genome-editing technology to manipulate lentiviral vectors. Soon after, I began working as a Scientific Officer at The Institute of Cancer Research, where I gained experience in genetically profiling primary patient samples through microarrays and next-generation sequencing. This exposure to oncological research, together with my interests in genetics and immunopathology, lead me to pursue a PhD in the O'Loghlen Lab.
Sarath Leaslie Kurichiyil - MSc Regenerative Medicine
Tamanna Shikh-Bahaei - iBS Experimental Pathology
Sana Abdullah - MSc Regenerative Medicine
Midusa Mahenthiran - iBS Experimental Pathology