2025

• Cervus elaphus antler extract mixture enhances mesenchymal cell supply to the growth plate and promotes bone growth. Choi JI† , Jee W† , Kim JH, Ko HM, Sung SH, Lee S-H, Kim S-R, Lee S, Park J-H, Kim YJ*, Jang H-J*. Submitted.

• Developmental hypoxia enhances kidney organoid complexity and maturity. Lim H, Kim D, Yoon H, Kang JH, Kim YJ, Kim DS, Park T-E. Adv Sci (Weinh). 2025 Aug 21:e01661. doi: 10.1002/advs.202501661. PMID: 40841925.

• Tissue-specific lncRNA GATA6-AS1 and its ortholog Moshe as essential regulators of aortic valve development. Kim NJ, Moon EH, Oh JH, Kim HM, Sung SH, Kim HS, Kim CY, Im YJ, Turner JE, Lee YJ, Kim YJ, Cho JY. BMB Rep. 2025 Apr;58(4):175-182. doi: 10.5483/BMBRep.2024-0208. PMID: 40176602

• Stem cell-based approaches in Parkinson's Disease research. Kim MS, Yoon S, Choi J, Kim YJ*, Lee G*. Int J Stem Cells. 2025 Feb 28;18:21-36. doi: 10.15283/ijsc23169. PubMed PMID: 38449089.

• Adhesive and conductive fibrous hydrogel bandages for effective peripheral nerve regeneration. Jin S, Jung H, Song J, Kim S, Yoon S, Kim JH, Kim YJ, Son D, Shin M. Adv Healthc Mater. 2025 Jan 23;e2403722. doi: 10.1002/adhm.202403722. PMID: 39846266

2024

• An innovative strategy harnessing self-activating CAR-NK cells to mitigate TGF-β1-driven immune suppression. Shin SH, Lee YE, Yoon H-N, Yuk CM, An JY, Seo M, Yoon S, Oh M-S, Shin SC, Kim JH, Kim YJ, Kim J-C, Kim SC, Jang M. Biomaterials. 2024 Oct 10;314-122888. doi: 10.1016/j.biomaterials.2024.122888.

• Synergistic effect of Wharton's jelly-derived mesenchymal stem cells and insulin on Schwann cell proliferation in Charcot-Marie-Tooth disease type 1A treatment. Oh S†, Kim H†, Park SE, Kim JH, Kim YJ, Choi S, Oh S, Jeon HB*, Chang JW*. Neurobiol Dis. 2024 Nov 12;203:106725. doi: 10.1016/j.nbd.2024.106725.

• Clinical manifestations of facial nerve schwannoma in Korea. Kim YJ, Choi HS, Kim SS, Lee JM, Yeo SG. J Korean Skull Base Soc. 2024 May 30; 19(1):1-10. doi: 10.55911/JKSBS.24.0003.

• SARS-CoV-2 infection exacerbates the cellular pathology in Parkinson's disease progression in human dopaminergic neurons and a mouse model. Lee B†, Choi HN†, Che YH†, Ko M†, Seong HM, Jo MG, Kim SH, Song C, Yoon S, Choi J, Kim JH, Kim M, Lee MY, Park SW, Kim HJ, Kim SJ, Moon DS, Lee S, Park JH, Yeo SG, Everson RG, Kim YJ, Hong KW, Roh IS, Lyoo KS*, Kim YJ*, Yun SP*. Cell Rep Med. 2024 May 21;5(5):101570. doi: 10.1016/j.xcrm.2024.101570. PubMed PMID: 38749422.

• Expression of ChAT and nNOS in the central nerve system following facial nerve injury. Lee JM, Yoo MC, Kim YJ, Kim SS, Yeo SG. Antioxidants (Basel). 2024 May 12;13(5). doi: 10.3390/antiox13050595. PubMed PMID: 38790700; PubMed Central PMCID: PMC11118893.

• Generation of an induced pluripotent stem cell line (PNUYHi002-A) from a patient with Alzheimer's disease carrying PRNP M232R variant. Kim MK , Kim Y, Lee N, Moon HJ, Lee JH, Kim EJ, Kim YJ, Kim J-H, Jung N-Y. Stem Cell Res. 2024 Apr;76:103361. doi: 10.1016/j.scr.2024.103361. PubMed PMID: 38437769.

• Empowering pancreatic tumor homing with augmented anti-tumor potency of CXCR2-tethered CAR-NK cells. Yoon JH, Yoon H-N, Kang HJ, Yoo H, Choi MJ, Chung J-Y, Seo M, Kim M, Lim SO, Kim YJ, Lee J-K, Jang M. Molecular Therapy Oncology. 2024 Mar 21;32(1):200777. doi: 10.1016/j.omton.2024.200777. PubMed PMID: 38596297; PubMed Central PMCID: PMC10926211.

• Autophagy genes and otitis media outcomes. Kim YJ, Rim HS, Kim JH, KIm SS, Yeo JH, Yeo SG. Clin Pract. 2024 Feb 6;14(1):293-304. doi: 10.3390/clinpract14010023. PubMed PMID: 38391409; PubMed Central PMCID: PMC10888475.

2023

• Induction of autophagy and its role in peripheral nerve regeneration after peripheral nerve injury. Yon DK, Kim YJ, Park DC, Jung SY, Kim SS, Yeo JH, Lee J, Lee JM, Yeo SG. Int J Mol Sci. 2023 Nov 11;24(22):16219. doi: 10.3390/ijms242216219. PMID: 38003409.

• Enhancing viability of human embryonic stem cells during cryopreservation via RGD-REP-mediated activation of FAK/AKT/FoxO3a signaling pathway. Kim JH, Choi JI, Che YH, Sung SH, Lee H, Lee S, Park J-H, Lee Y-I, Lee Y-S, Jeon WB, Kim YJ. Tissue Eng Regen Med. 2023 Dec;20(7):1133-1143. doi: 10.1007/s13770-023-00568-3. Sharedit link for full article PDF download

• Peripheral neuron-organoid interaction induces colonic epithelial differentiation via non-synaptic substance P secretion. Che YH†, Choi IY†, Song CE†, Park C, Lim SK, Kim JH, Sung SH, Park JH, Lee S*, Kim YJ*. Int J Stem Cells. 2023 Aug 31;16(3):269-280. doi: 10.15283/ijsc23026. PMID: 37385635. Featured as a cover image.

• Comparison of ER stress mRNA expression between chronic otitis media with and without cholesteatoma. Kang DW, Kim YJ, Kim SS, Kim YI, Doo JG, Kim SH, Yeo SG. J Int Adv Otol. 2023 Jul;19(4):271-276. doi: 10.5152/iao.2023.21182. PMID: 37528590.

• Effects of electrical stimulation on facial paralysis recovery after facial nerve injury: a review on preclinical and clinical studies. Yoo MC, Kim JH, Kim YJ, Jung J, Kim SS, Kim SH, Yeo SG. J Clin Med. 2023 Jun 19;12(12). doi: 10.3390/jcm12124133. Review. PMID: 37373826.

• Symmetry breaking of human pluripotent stem cells in micropattern generates a polarized spinal cord-like organoid with dorsoventral organization. Seo K, Cho S, Shin H, Shin A, Lee JH, Kim JH, Lee B, Jang H, Kim Y, Cho HM, Park Y, Kim HY, Lee T, Park WY, Kim YJ, Yang E, Geum D, Kim H, Cho IJ, Lee S, Ryu JR, Sun W. Adv Sci (Weinh). 2023 May 12;:e2301787. doi: 10.1002/advs.202301787. PMID: 37170679.

2022

• Direct neuronal infection of SARS-CoV-2 reveals cellular and molecular pathology of chemosensory impairment of COVID-19 patients. Lyoo KS†, Kim HM†, Lee B†, Che YH, Kim SJ, Song D, Hwang W, Lee S, Park JH, Na W*, Yun SP*, Kim YJ*. Emerg Microbes Infect. 2022 Dec;11(1):406-411. doi: 10.1080/22221751.2021.2024095. PubMed PMID: 34962444; PubMed Central PMCID: PMC8803065.

• Pharmacological inhibition of AIMP2 aggregation attenuates ⍺-synuclein aggregation and toxicity in Parkinson's disease. Shin JY, Lee B, Ham S, Kim JH, Kim H, Kim H, Jo MG, Kim HJ, Park SW, Kweon HS, Kim YJ, Yun SP*, Lee Y*. Biomed Pharmacother. 2022 Oct 22;156:113908. doi: 10.1016/j.biopha.2022.113908. PMID: 36283223.

• New insights into the epitranscriptomic control of pluripotent stem cell fate. Che Y, Lee H, Kim YJ. Exp Mol Med. 2022 Oct;54(10):1643-1651. doi: 10.1038/s12276-022-00824-x. Epub 2022 Oct 21. Review. PMID: 36266446; PMCID: PMC9636187.

• Role of the WNT/β-catenin/ZKSCAN3 pathway in regulating chromosomal instability in colon cancer cell lines and tissues. Cho YE, Kim JH, Che YH, Kim YJ, Sung JY, Kim YW, Choe BG, Lee S, Park JH. Int J Mol Sci. 2022 Aug 18;23(16). doi: 10.3390/ijms23169302. MID: 36012568; PMCID: PMC9409321.

• Understanding the cellular pathogenesis of COVID-19 symptoms using organoid technology. Che YH., Kim YJ. Organoid. 2022 Jul 20;2(1):e16. doi:10.51335/organoid.2022.2.e16.

• Direct conversion to achieve glial cell fates: oligodendrocytes and Schwann cells. Yun W., Kim YJ., Lee G. Int J Stem Cells. 2022 Feb 28;15(1):14-252022 Feb 28;15(1):14-25. doi: 10.15283/ijsc22008. PMID: 35220289; PMCID: PMC8889328.

• OCT4-induced oligodendrocyte progenitor cells promote remyelination and ameliorate disease. Yun W, Choi KA, Hwang I, Zheng J, Park M, Hong W, Jang AY, Kim JH, Choi W, Kim DS, Kim IY, Kim YJ, Liu Y, Yoon BS, Park G, Song G, Hong S, You S. NPJ Regen Med. 2022 Jan 13;7(1):4. doi: 10.1038/s41536-021-00199-z. PMID: 35027563; PMCID: PMC8758684.

2021

• NOP53 suppresses autophagy through ZKSCAN3-dependent and -independent pathways. Cho YE, Kim YJ, Lee S, Park JH. Int J Mol Sci. 2021 Aug 27;22(17):9318. doi: 10.3390/ijms22179318. PubMed PMID: 34502226.

• Inhibition of the combinatorial signaling of Transforming growth factor-beta and NOTCH promotes myotube formation of human pluripotent stem cell-derived skeletal muscle progenitor cells. Choi IY, Lim HT, Che YH, Lee G, Kim YJ. Cells. 2021 Jun 30;10(7). doi: 10.3390/cells10071649. PubMed PMID: 34209364.

• A metastasis suppressor Pt-dendrimer nanozyme for the alleviation of glioblastoma. An JM, Ju Y, Kim JH, Lee H, Jung Y, Kim J, Kim YJ, Kim J, Kim D. J Mater Chem B. 2021 May 19;9(19):4015-4023. doi: 10.1039/d1tb00425e. PubMed PMID: 33954328.

• Novel culture system via wirelessly controllable optical stimulation of the FGF signaling pathway for human and pig pluripotency. Choi IY, Lim H, Huynh A, Schofield J, Cho HJ, Lee H, Andersen P, Shin JH, Heo WD, Hyun SH, Kim YJ, Oh Y, Kim H, Lee G. Biomaterials. 2021 Feb;269:120222. doi: 10.1016/j.biomaterials.2020.120222. Epub 2020 Jul 15. PubMed PMID: 32736809.

• CReVIS-Seq: A highly accurate and multiplexable method for genome-wide mapping of lentiviral integration sites. Kim HS, Hwang GH, Lee HK, Bae T, Park SH, Kim YJ, Lee S, Park JH, Bae S, Hur JK. Mol Ther Methods Clin Dev. 2021 Mar 12;20:792-800. doi: 10.1016/j.omtm.2020.10.012. eCollection 2021 Mar 12. PubMed PMID: 33768124; PubMed Central PMCID: PMC7961857.

2020

• Tyrosine Phosphorylation of the Kv2.1 Channel Contributes to Injury in Brain Ischemia. Song MY, Hwang JY, Bae EJ, Kim S, Kang HM, Kim YJ, Park C, Park KS. Int J Mol Sci. 2020 Dec 15;21(24). doi: 10.3390/ijms21249538. PubMed PMID: 33333928; PubMed Central PMCID: PMC7765428.

• Transcriptional landscape of myogenesis from human pluripotent stem cells reveals a key role of TWIST1 in maintenance of skeletal muscle progenitors. Choi IY, Lim H, Cho HJ, Oh Y, Chou BK, Bai H, Cheng L, Kim YJ, Hyun S, Kim H, Shin JH, Lee G. Elife. 2020 Feb 3;9. doi: 10.7554/eLife.46981. PubMed PMID: 32011235; PubMed Central PMCID: PMC6996923.

2019

• Comparison of three congruent patient-specific cell types for the modelling of a human genetic Schwann-cell disorder. Mukherjee-Clavin B, Mi R, Kern B, Choi IY, Lim H, Oh Y, Lannon B, Kim KJ, Bell S, Hur JK, Hwang W, Che YH, Habib O, Baloh RH, Eggan K, Brandacher G, Hoke A, Studer L, Kim YJ*, Lee G*. Nat Biomed Eng. 2019 Jul;3(7):571-582. doi: 10.1038/s41551-019-0381-8. Epub 2019 Apr 8. PubMed PMID: 30962586; PubMed Central PMCID: PMC6612317.

• Specificity Assessment of CRISPR Genome Editing of Oncogenic EGFR Point Mutation with Single-Base Differences. Bae T, Kim H, Kim JH, Kim YJ, Lee SH, Ham BJ, Hur JK. Molecules. 2019 Dec 22;25(1). doi: 10.3390/molecules25010052. PubMed PMID: 31877894; PubMed Central PMCID: PMC6982904.

• A benzothioate native chemical ligation-based cysteine-selective fluorescent probe. Kim NH, Moon H, Kim HJ, Huh Y, Kim YJ*, Kim BM*, Kim D*. Dyes and Pigments. 2019 Dec;171:107764. doi: 10.1016/j.dyepig.2019.107764.

2018

• Visualization of altered hippocampal connectivity in an animal model of Alzheimer's disease. Jeon SG*, Kim YJ*, Kim KA, Mook-Jung I, Moon M. Mol Neurobiol. 2018 Oct;55(10):7886-7899. doi: 10.1007/s12035-018-0918-y. Epub 2018 Feb 27. PubMed PMID: 29488134; PubMed Central PMCID: PMC6132739.

2017

• Role of the JNK pathway in Varicella-Zoster Virus lytic infection and reactivation. Kurapati S, Sadaoka T, Rajbhandari L, Jagdish B, Shukla P, Ali MA, Kim YJ, Lee G, Cohen JI, Venkatesan A. J Virol. 2017 Sep 1;91(17). doi: 10.1128/JVI.00640-17. Print 2017 Sep 1. PubMed PMID: 28637759; PubMed Central PMCID: PMC5553188.

• GLTSCR2 promotes the nucleoplasmic translocation and subsequent degradation of nucleolar ARF. Lee S, Cho YE, Kim SH, Kim YJ, Park JH. Oncotarget. 2017 Mar 7;8(10):16293-16302. doi: 10.18632/oncotarget.9957. PubMed PMID: 27323397; PubMed Central PMCID: PMC5369963.

2016

• Design of a high-throughput human neural crest cell migration assay to indicate potential developmental toxicants. Nyffeler J, Karreman C, Leisner H, Kim YJ, Lee G, Waldmann T, Leist M. ALTEX. 2017;34(1):75-94. doi: 10.14573/altex.1605031. Epub 2016 Jul 27. PubMed PMID: 27463612.

• The pharmacological stimulation of Nurr1 improves cognitive functions via enhancement of adult hippocampal neurogenesis. Kim JI, Jeon SG, Kim KA, Kim YJ, Song EJ, Choi J, Ahn KJ, Kim CJ, Chung HY, Moon M, Chung H. Stem Cell Res. 2016 Nov;17(3):534-543. doi: 10.1016/j.scr.2016.09.027. Epub 2016 Sep 28. PubMed PMID: 27788475.

• Functional Coupling with Cardiac Muscle Promotes Maturation of hPSC-Derived Sympathetic Neurons. Oh Y, Cho GS, Li Z, Hong I, Zhu R, Kim MJ, Kim YJ, Tampakakis E, Tung L, Huganir R, Dong X, Kwon C, Lee G. Cell Stem Cell. 2016 Jul 7;19(1):95-106. doi: 10.1016/j.stem.2016.05.002.

• Concordant but Varied Phenotypes among Duchenne Muscular Dystrophy Patient-Specific Myoblasts Derived using a Human iPSC-Based Model. Choi IY, Lim H, Estrellas K, Mula J, Cohen TV, Zhang Y, Donnelly CJ, Richard JP, Kim YJ, Kim H, Kazuki Y, Oshimura M, Li HL, Hotta A, Rothstein J, Maragakis N, Wagner KR, Lee G. Cell Rep. 2016 Jun 7;15(10):2301-12. doi: 10.1016/j.celrep.2016.05.016.

• c-Jun N-terminal kinase regulates the nucleoplasmic translocation and stability of nucleolar GLTSCR2 protein. Lee S, Cho YE, Kim YJ, Park JH. Biochem Biophys Res Commun. 2016 Mar 25;472(1):95-100. doi: 10.1016/j.bbrc.2016.02.070.

The Kim Lab launching at 2016