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Most of the time, what matters most is the number of words matched, the proximity between matched words and how close to the beginning of the attribute the matches are. In your case, all of those criteria rank equal, which explains why the custom ranking is taken into account.

Something beyond setting this up that is confusing me as well is what if there are multiple partial matches - I don't think it is reasonable to complicate this with a "best match" component, but I'm not sure how to deal with this part.

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From your comment I understand that a "partial match" means the occurrence of the full string in column B as a substring in column A. You can use the SEARCHfunction for that. However, as search will only check the appearing in one cell, you need to combine it as an array formula:

With social media and dating apps, our social circles have broadened and made searching for the perfect match both easier and more difficult by leveling the playing field. But what exactly is a perfect match?

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The extremely rare match was the result of Jessica Hardaway donating bone marrow to her older sister, Kristin Hamner, as a child. That was followed by a kidney donation 30 years later when she donated a kidney to her older sister in March.

Yes, I intro'd this point by referring to two fictionalized accounts. But y'all, in real life, I sit in counseling sessions all of the time that consist of two people who are either extremely disappointed or flat-out pissed off that their partner, the one who they initially thought was perfect for them, has turned out to be any and everything but. And because they are so hurt by that, almost to the point of believing they've been betrayed, they figure that the appropriate response is to the end of the relationship so that they can make room to find true perfection.

Perfection Is Hella Overrated If you're out here looking for your perfect match, take a moment to ponder a particular definition of the word. To be perfect is to be "excellent or complete beyond practical or theoretical improvement". Aside from this being an impossibility for any human being (short of Christ himself), this definition alone is why I encourage people to desire a relationship that is healthy (functioning well), not perfect. Why? Because one of the most beautiful things about a healthy relationship is it consists of two people who are invested in helping the other to grow, evolve and mature into a better version of themselves. If the relationship was already "perfect", where would there be a need for any of this, since there is nothing that needs to be improved upon?

So yeah, let's start with one reason why a perfect match is a ridiculous notion is because most of us don't want something that doesn't require any improvement on some level. We merely want something that isn't toxic or counterproductive. And when it comes to that resolve, being in something that is healthy will suit us just fine. Next point.

Something that is needed, for any relationship to flourish, is maturity. And a part of what comes with being mature is having the kind of emotional intelligence that portrays a healthy level of empathy. When a person is empathetic, not only does it mean that they can identify with the thoughts and feelings of another person, but they are intentional about doing it. When someone expects perfection, whether it be from their partner or their relationship, it means that, whenever their partner makes a mistake (or sometimes even just a poor choice because that is not always or necessarily one and the same), the person leaves no room for forgiveness or even hearing their partner out because wanting perfection is wanting no room for improvement, remember?

That's the thing about perfection. It can have you out here being so focused on how much it can benefit you that you don't realize the painful boomerang that it creates when you fail to meet perfection's expectations. And that's why I say that it's a selfish way of thinking. You're not always going to do things perfectly, so don't expect your partner to.

I will die on the hill that, a perfect match leans on the side of being totally ridiculous because, how does that even happen when the two folks in the relationship aren't perfect themselves? Since they need to consistently improve, how could the connection not require the same mercy and grace? Anyone who declares they are a "perfect match" should revisit the word "perfect" often. Because again, if you are professing that your relationship cannot stand to improve, you are just fooling yourself. Everything and everyone needs improvement. That's not a bad thing. That's just the truth.

Now that perfection has been broken down, all the way to the floor, does that mean that absolutely beautiful examples of love don't exist? I am absolutely NOT saying that. I know some people who, while I don't refer to them as being a "perfect match", it is extremely evident that they complement each other exceptionally well. I'll even go so far as to call them "soulmates" because I don't romanticize that term.

The Hebrew word for soulmate is "beshert" which translates into meaning things like "destined", "inevitable" or "meant to be". And yes, some people, I believe, when they allow God to lead them in their lives, they are brought to the mate who best suits them. That doesn't mean their soulmate is their perfect match, though. Actually, from the way I see it, it means God has brought them to someone who will best improve them as they do the same for their partner. A soulmate or bashert is about an amazing complement (check out "If He's Right For You, He Will COMPLEMENT Your Life") NOT a perfect match.

In the first apples-to-apples comparison, researchers have shown that half-matched donor recipients do just as well as full-match recipients, which could be a major advance for minorities, and others without good access to full-match donors. The study was published in the journal Biology of Blood and Marrow Transplantation.

"This is the first study to compare the gold standard to a half-match using an identical protocol," says Neal Flomenberg, M.D., Chair of the Department of Medical Oncology at Thomas Jefferson University and the senior author on the study. "The field has debated whether the differences in outcomes between full and partial matches were caused by the quality of the match or by all the procedures the patient goes through before and after the donor cells are administered. We haven't had a clear answer," he adds.

In this study, the researchers compared 3-year outcomes data from half-match donor recipients who had been transplanted using the Jefferson Two-Step protocol with full-matched donors receiving the same Two-Step approach. Three years after transplant approximately 70 percent of the patients in both groups were still alive and cancer free.

If it's as good, but not better, what's the advantage of a half-match? First, not everyone will have a full match in their family. In fact, according to the National Marrow Donor Program, only 30 percent of patients will have a family member whose cells are a full match. Unrelated donor registries, or cord blood registries, can be an alternate source, but the process can be expensive and time consuming for patients who may only have a short window in which to be treated (bone marrow transplants are most successful while a patient is in remission). Half-match donors are much easier to find among a patient's relatives, and can be ready to donate within days. Registries also tend to lack matches for minorities.

Although there are several methods for performing a half-match, also known as a haploidentical transplant, the jury is still out about the most effective approach. "There are some major advantages to the two step approach," says first author Sameh Gaballa, M.D., Assistant Professor in the Department of Medical Oncology at Thomas Jefferson University and a researcher at the Sidney Kimmel Cancer Center at Thomas Jefferson University. First, rather than extracting stem cells from the bone marrow, which can be painful and risky for donors who can sometimes require blood transfusions, the Two-Step method uses stem cells harvested from the blood. Using the blood as a source of stem cells is not only easier for the donor, but it gives physicians the ability to control the exact number of immune cells, called T cells, which fight the cancer, and donor stem cells that replenish the patient's depleted blood supply (the two donor components of the therapy). "Making sure we have just the right amount of T cells makes a difference. Too few and you might not control the cancer, resulting in a relapse or rejection of the transplant. Too many and you run the risk of severe graft-versus host disease, which can endanger the patient," says Dr. Gaballa.

Perfect Match PCR enhancer is an additive that increases the specificity and yield of primary PCR amplification products. When added to genomic in vitro amplification reactions, Perfect Match PCR enhancer destabilizes many mismatched primer-template complexes that would otherwise result in a heterogeneous population of amplified molecules (Figure 1). Perfect Match PCR enhancer is an effective solution for the problem of PCR artifacts generated by false priming by removing secondary structure for reactions present within the target sequence. 17dc91bb1f