Publications

2021

Dinet C, Michelot A, Herrou J, Mignot T (2021). Linking single-cell decisions to collective behaviours in social bacteria. Philos Trans R Soc Lond B Biol Sci. 376(1820):20190755. PMID: 33487114.

2020

Mercier R, Bautista S, Delannoy M, Gibert M, Guiseppi A, Herrou J, Mauriello EMF, Mignot T (2020). The polar Ras-like GTPase MglA activates type IV pilus via SgmX to enable twitching motility in Myxococcus xanthus. PNAS. 202002783. PMID: 33093210.

Islam ST, Vergara Alvarez I, Saïdi F, Guiseppi A, Vinogradov E, Sharma G, Espinosa L, Morrone C, Brasseur G, Guillemot JF, Benarouche A, Bridot JL, Ravicoularamin G, Cagna A, Gauthier C, Singer M, Fierobe HP, Mignot T, Mauriello EMF (2020). Modulation of bacterial multicellularity via spatio-specific polysaccharide secretion. PLoS Biol. 18(6):e3000728. PMID: 32516311.

Zhang H, Mulholland GA, Seef S, Zhu S, Liu J, Mignot T, Nan B (2020). Establishing rod shape from spherical, peptidoglycan-deficient bacterial spores. PNAS. 117(25):14444-14452. PMID: 32513721.

Mauriello EMF (2020). How an unusual chemosensory system forms arrays on the bacterial nucleoid. Biochem Soc Trans. pii: BST20180450. PMID: 32129822.

Herrou J, Mignot T (2020). Dynamic polarity control by a tunable protein oscillator in bacteria. Curr Opin Cell Biol. 62:54-60. PMID: 31627169.

2019

Guiseppi A, Vicente JJ, Herrou J, Byrne D, Barneoud A, Moine A, Espinosa L, Basse MJ, Molle V, Mignot T, Roche P, Mauriello EMF (2019). A divergent CheW confers plasticity to nucleoid-associated chemosensory arrays. PLoS Genet. 15(12):e1008533. PMID: 31860666.

Galicia C, Lhospice S, Varela PF, Trapani S, Zhang W, Navaza J, Herrou J, Mignot T, Cherfils J (2019). MglA functions as a three-state GTPase to control movement reversals of Myxococcus xanthus. Nat Commun. 10(1):5300. PMID: 31757955.

Baranwal J, Lhospice S, Kanade M, Chakraborty S, Gade PR, Harne S, Herrou J, Mignot T, Gayathri P (2019). Allosteric regulation of a prokaryotic small Ras-like GTPase contributes to cell polarity oscillations in bacterial motility. PLoS Biol. 17(9):e3000459. PMID: 31560685.

Tréguier J, Bugnicourt L, Gay G, Diallo M, Islam ST, Toro A, David L, Théodoly O, Sudre G, Mignot T (2019). Chitosan films for microfluidic studies of single bacteria and perspectives for antibiotic susceptibility testing. MBio.10(4). pii: e01375-19. PMID: 31431549.

Petiti M, Serrano B, Faure L, Lloubes R, Mignot T, Duché D (2019). Tol energy-driven localization of Pal and anchoring to the peptidoglycan promote outer-membrane constriction. J Mol Biol. pii: S0022-2836(19)30323-7. PMID: 31153904.

2018

Theodoly O, Garcia-Seyda N, Bedu F, Luo X, Gabriele S, Mignot T, Giermanska J, Chapel JP, Métivier M, Valignat MP (2018). Live nanoscopic to mesoscopic topography reconstruction with an optical microscope for chemical and biological samples. PLoS One. 13(12):e0207881. PMID: 30540777.

Guzzo M, Murray SM, Martineau E, Lhospice S, Baronian G, My L, Zhang Y, Espinosa L, Vincentelli R, Bratton BP, Shaevitz JW, Molle V, Howard M, Mignot T (2018). A gated relaxation oscillator mediated by FrzX controls morphogenetic movements in Myxococcus xanthus. Nat Microbiol. 3(8):948-959. PMID: 30013238.

Mauriello EM, Jones C, Moine A, Armitage JP (2018). Cellular targeting and segregation of bacterial chemosensory systems. FEMS Microbiol Rev. 42(4):462-476. PMID: 29945173.

Fu G, Bandaria JN, Le Gall AV, Fan X, Yildiz A, Mignot T, Zusman DR, Nan B (2018). MotAB-like machinery drives the movement of MreB filaments during bacterial gliding motility. Proc Natl Acad Sci USA. 115(10):2484-2489. PMID: 29463706.

Chapelais-Baron M, Goubet I, Péteri R, Pereira MF, Mignot T, Jabveneau A, Rosenfeld E (2018). Colony analysis and deep learning uncover 5-hydroxyindole as an inhibitor of gliding motility and iridescence in Cellulophaga lytica. Microbiology. 164(3):308-321. PMID: 29458680.

2017

Moine A, Espinosa L, Martineau E, Yaikhomba M, Jazleena PJ, Byrne D, Biondi EG, Notomista E, Brilli M, Molle V, Gayathri P, Mignot T, Mauriello EM (2017). The nucleoid as a scaffold for the assembly of bacterial signaling complexes. PLoS Genet. 13(11):e1007103. PMID: 29161263.

Mignot T, Nöllmann M (2017). New insights into the function of a versatile class of membrane molecular motors from studies of Myxococcus xanthus surface (gliding) motility. Microb Cell. 4(3):98-100. PMID: 28357395.

Viala JP, Prima V, Puppo R, Agrebi R, Canestrari MJ, Lignon S, Chauvin N, Méresse S, Mignot T, Lebrun R, Bouveret E (2017). Acylation of the type 3 secretion system translocon using a dedicated acyl carrier protein. PLoS Genet. 13(1):e1006556. PMID: 28085879.

2016

Faure LM, Fiche JB, Espinosa L, Ducret A, Anantharaman V, Luciano J, Lhospice S, Islam ST, Tréguier J, Sotes M, Kuru E, Van Nieuwenhze MS, Brun YV, Théodoly O, Aravind L, Nollmann M, Mignot T (2016). The mechanism of force transmission at bacterial focal adhesion complexes. Nature. 539(7630):530-535. PMID: 27749817.

Mercier R, Mignot T (2016). Regulations governing the multicellular lifestyle of Myxococcus xanthus. Curr Opin Microbiol. 34:104-110. PMID: 27648756.

Zoued A, Durand E, Brunet YR, Spinelli S, Douzi B, Guzzo M, Flaugnatti N, Legrand P, Journet L, Fronzes R, Mignot T, Cambillau C, Cascales E (2016). Priming and polymerization of a bacterial contractile tail structure. Nature. 531(7592):59-63. PMID: 26909579.

Kientz B, Luke S, Vukusic P, Péteri R, Beaudry C, Renault T, Simon D, Mignot T, Rosenfeld E (2016). A unique self-organization of bacterial sub-communities creates iridescence in Cellulophaga lytica colony biofilms. Sci Rep. 6:19906. PMID: 26819100.

2015

Islam ST, Mignot T (2015). The mysterious nature of bacterial surface (gliding) motility: a focal adhesion-based mechanism in Myxococcus xanthus. Semin Cell Dev Biol. 46:143-154. PMID: 26520023.

Fievet A, Ducret A, Mignot T, Valette O, Robert L, Pardoux R, Dolla AR, Aubert C (2015). Single-cell analysis of growth and cell division of the anaerobe Desulfovibrio vulgaris Hildenborough. Front Microbiol. 6:1378. PMID: 26696987.

Guzzo M, Agrebi R, Espinosa L, Baronian G, Molle V, Mauriello EM, Brochier-Armanet C, Mignot T (2015). Evolution and design governing signal precision and amplification in a bacterial chemosensory pathway. PLoS Genet. 11(8):e1005460. PMID: 26291327.

Treuner-Lange A, Macia E, Guzzo M, Hot E, Faure L, Jakobczak B, Espinosa L, Alcor D, Ducret A, Keilberg D, Castaing JP, Lacas Gervais S, Franco M, Søgaard-Andersen L, Mignot T (2015). The small G-protein MglA connects to the MreB actin cytoskeleton at bacterial focal adhesions. J Cell Biol. 210(2):243-256. PMID: 26169353.

Brunet YR, Khodr A, Logger L, Aussel L, Mignot T, Rimsky S, Cascales E (2015). H-NS silencing of the Salmonella pathogenicity island 6-encoded type VI secretion system limits Salmonella enterica serovar Typhimurium interbacterial killing. Infect Immun. 83(7):2738-2750. PMID: 25916986.

Agrebi R, Wartel M, Brochier-Armanet C, Mignot T (2015). An evolutionary link between capsular biogenesis and surface motility in bacteria. Nat Rev Microbiol. 13(5):318-326. PMID: 25895941.

2014

Moine A, Agrebi R, Espinosa L, Kirby J, Zusman D, Mignot T, Mauriello EM (2014) Functional organization of a multimodular bacterial chemosensory apparatus. PloS Genet. 10(3):e1004164. PMID: 24603697.

2013

Wartel M, Ducret A, Thutupalli S, Czerwinski F, Le Gall AV, Mauriello EM, Bergham P, Brun Y, Shaevitz J, Mignot T (2013). A versatile class of cell surface directional motors gives rise to gliding motility and sporulation in Myxococcus xanthus. PloS Biol. 11(12):e1001728. PMID: 24339744.

Cattoni DI, Fiche JB, Valeri A, Mignot T, Nöllmann M (2013). Super-resolution imaging of bacteria in a microfluidics device. PLoS One. 8(10):e76268. PMID: 24146850.

Ducret A, Fleuchot B, Bergham P, Mignot T (2013). Direct live imaging of cell-cell protein transfer by transient outer membrane fusion in Myxococcus xanthus. Elife. 2:e00868. PMID: 23898400.

Brunet YR, Espinosa L, Harchouni S, Mignot T, Cascales E (2013). Imaging type-VI secretion-mediated bacterial killing. Cell Reports. 3(1):36-41. PMID: 23291094.

Ducret A, Théodoly O, Mignot T (2013). Single cell microfluidic studies of bacterial motility. Methods Mol Biol. 966:97-107. PMID: 23299730.

Mauriello EM (2013). Cell biology of bacterial sensory modules. Front Biosci (Landmark Ed).18:928-43. PMID: 23747858.

2012

Kientz B, Ducret A, Luke S, Vukusic P, Mignot T, Rosenfeld E (2012) Glitter-like iridescence within the Bacteroidetes especially Cellulophaga spp.: optical properties and correlation with gliding motility. PloS One. 7(12):e52900. PMID: 23300811.

Amster-Choder O, Mignot T (2012). Growth and development: prokaryotes. Curr Opin Microbiol. 15(6):705-706. PMID: 23194653.

Mauriello EM (2012). Cell biology of bacterial sensory modules. Front Biosci. 18:928-943. PMID: 23747858.

Zhang Y, Guzzo M, Ducret A, Li YZ, Mignot T (2012). A dynamic response regulator protein modulates G-protein-dependent polarity in the bacterium Myxococcus xanthus. PLoS Genet. 8(8):e1002872. PMID: 22916026.

Ducret A, Valignat MP, Mouhamar F, Mignot T, Théodoly O (2012). Wet-surface-enhanced ellipsometric contrast microscopy identifies slime as a major adhesion factor during bacterial surface motility. Proc Natl Acad Sci USA. 109(25):10036-10041. PMID: 22665761.

Zhang Y, Ducret A, Shaevitz J, Mignot T (2012). From individual cell motility to collective behaviors: insights from a prokaryote, Myxococcus xanthus. FEMS Microbiol Rev. 36(1):149-164. PMID: 22091711.

2011

Luciano J, Agrebi R, Le Gall AV, Wartel M, Fiegna F, Ducret A, Brochier-Armanet C, Mignot T. (2011). Emergence and modular evolution of a novel motility machinery in bacteria. PLoS Genet. 7(9):e1002268. PMID: 21931562.

Sun M, Wartel M, Cascales E, Shaevitz JW, Mignot T (2011). Motor-driven intracellular transport powers bacterial motility. Proc Natl Acad Sci USA. 108(18):7559-7564. PMID: 21482768.

2010

Zhang Y, Franco M, Ducret A, Mignot T (2010). A bacterial Ras-like small GTP-binding protein and its cognate GAP establish a dynamic spatial polarity axis to control directed motility. PLoS Biol. 8(7):e1000430. PMID: 20652021.

Mauriello EM, Mignot T, Yang Z, Zusman DR (2010). Gliding motility revisited: how do the myxobacteria move without flagella ? Microbiol Mol Biol Rev. 4(2):229-249. PMID: 20508248.

Mauriello EM, Mouhamar F, Nan B, Ducret A, Dai D, Zusman DR, Mignot T (2010). Bacterial motility complexes require the actin-like protein, MreB and the Ras homologue, MglA. EMBO J. 29(2):315-326. PMID: 19959988.

2009

Ducret A, Maisonneuve E, Notareschi P, Grossi A, Mignot T, Dukan S (2009). A microscope automated fluidic system to study bacterial processes in real time. PLoS One. 4(9):e7282. PMID: 19789641.

2008

Mignot T, Shaevitz JW (2008). Active and passive mechanisms of intracellular transport and localization in bacteria. Curr Opin Microbiol. 11(6):580-585. PMID: 19007909.

Mignot T, Kirby JR (2008). Genetic circuitry controlling motility behaviors in Myxococcus xanthus. Bioessays. 30(8):733-743. PMID: 18623059.

2007

Mignot T (2007). The elusive engine in Myxococcus xanthus gliding motility. Cell Mol Life Sci. 64(21): 2733-2745. PMID: 17653507.