Harman Research Group - Publications

[174] Electron-Deficient Ru(II) Complexes as Catalyst Precursors for Ethylene Hydrophenylation. Xiaofan Jia , Songyuan Tian, Philip J. Shivokevich, W. Dean Harman, Diane A. Dickie and T. Brent Gunnoe*. Inorganics, 2022, 10, 76.

[173] Phenyl Sulfones: A Route to a Diverse Family of Trisubstituted Cyclohexenes from Three Independent Nucleophilic Additions. Spenser R. Simpson, Paolo Siano, Daniel J. Siela, Louis A. Diment, Brian C. Song, Karl S. Westendorff, Megan N. Ericson, Kevin D. Welch, Diane A. Dickie, and W. Dean Harman*. J. Am. Chem. Soc. 2022, 144, 21, 9489–9499

[172] Hydroamination of Dihapto-Coordinated Benzene and Diene Complexes of Tungsten: Fundamental Studies and the Synthesis of γ-Lycorane. Katy B. Wilson,Hannah S. Nedzbala,Spenser R. Simpson,Megan N. Ericson,Karl S. Westendorff,Mahendra D. Chordia,Diane A. Dickie,W. Dean Harman . Chimica Acta, 2021 (Dedicated to Prof. E. Peter Kündig on the occasion of his 75th birthday)

[171] Dihapto-Coordination of Electron-Deficient Arenes with Group 6 Dearomatization Agents. Jacob A. Smith, Spenser Simpson, Karl S. Westendorf, Justin Weatherford-Pratt, Jeffery T. Myers, Justin H. Wilde, Diane A. Dickie, and W. Dean Harman. Organometallics 2020.

[170] A Highly Divergent Synthesis of 3-Aminotetrahydropyridines. Justin H. Wilde, Diane A. Dickie, and W. Dean Harman. J. Org. Chem. 2020. DOI: 10.1021/acs.joc.0c00853.

[169] Preparation of cyclohexene isotopologues and stereoisotopomers from benzene. Jacob A. Smith, Katy B. Wilson, Reilly E. Sonstrom, Patrick J. Kelleher, Kevin D. Welch, Emmit K. Pert, Karl S. Westendorff, Diane A. Dickie, Xiaoping Wang, Brooks H. Pate & W. Dean Harman. Nature 2020, 581, 288–293.

[168] Spatial Recognition Within Terpenes: Redox and H-bond Promoted Linkage Isomerizations and the Selective Binding of Complex Alkenes. Steven J. Dakermanji, Karl S. Westendorff, Emmit K. Pert, Katy B. Wilson, Jeffery T. Myers, Justin H. Wilde, Diane A. Dickie, Kevin D. Welch, and W. Dean Harman. Organometallics 2020, 39, 10, 1961–1975.

[167] Molybdenum-Promoted Dearomatization of Pyridines. Justin H. Wilde, Jeffery T. Myers, Diane A. Dickie, and W. Dean Harman. Organometallics 2020, 39, 8, 1288–1298.

[166] Michael–Michael Ring-Closure Reactions for a Dihapto-Coordinated Naphthalene Complex of Molybdenum. Jeffery T. Myers#, Justin H. Wilde#, Michal Sabat, Diane A. Dickie, W. Dean Harman. Organometallics 2020, 39, 8, 1404–1412. (#= co-first authorship)

[165] Molybdenum-Promoted Synthesis of Isoquinuclidines with Bridgehead CF3 Groups. Justin H. Wilde, Jacob A. Smith, Diane A. Dickie, W. Dean Harman J. Am. Chem. Soc. 2019, 141, 47, 18890-18899.

[164] Electron-Transfer Chain Catalysis of η2-Arene, η2-Alkene, and η2-Ketone Exchange on Molybdenum. Steven J. Dakermanji, Jacob A. Smith, Karl S. Westendorff, Emmit K. Pert, Andrew D. Chung, Jeffery T. Myers, Kevin D. Welch, Diane A. Dickie, W. Dean Harman. ACS Catal. 2019, 9, 12, 11274–11287.

[163] Highly Functionalized Cyclohexenes Derived from Benzene: Sequential Tandem Addition Reactions Promoted by Tungsten. Katy B. Wilson, Jacob A. Smith, Hannah S. Nedzbala, Emmit K. Pert, Steven J. Dakermanji, Diane A. Dickie, W. Dean Harman* J. Org. Chem. 2019, 84, 10, 6094–6116.

[162] Reversible modulation of the redox characteristics of acid-sensitive molybdenum and tungsten scorpionate complexes Alexander J. Heyer, ‡ Philip J. Shivokevich, ‡ Shelby L. Hooe, Kevin D. Welch, W. Dean Harman * and Charles W. Machan Dalton Transactions 2018,47, 6323-6332. (‡ = co-first authorship)

[161] Enantioenriched Molybdenum Dearomatization: Dissociative Substitution with Configurational Stability Philip J. Shivokevich†, Jeffery T. Myers†, Jacob A. Smith, Jared A. Pienkos, Steven J. Dakermanji, Emmit K. Pert, Kevin D. Welch, Carl O. Trindle, and W. Dean Harman* Organometallics, 2018, 37 (23), pp 4446–4456. Part of the Organometallic Complexes of Electrophilic Elements for Selective Synthesis special issue. († = co-first authorship)

[160] Group 6 Dihapto-Coordinate Dearomatization Agents for Organic Synthesis. Benjamin K. Liebov and W. Dean Harman, Chem. Rev. 2017, 117, 22, 13721–13755.

[159] Experiments and Direct Dynamics Simulation,s That Probe η²-Arene/Aryl Hydride Equilibria of Tungsten Benzene Complexes. Jacob A. Smith‡, Anna Schouten‡, Justin H. Wilde, Karl S. Westendorff, Diane A. Dickie, Daniel H. Ess*, and W. Dean Harman*, J. Am. Chem. Soc. 2020, 142, 38, 16437–16454. (‡ = co-first authorship)

[158] Sequential Tandem Addition to a Tungsten–Trifluorotoluene Complex: A Versatile Method for the Preparation of Highly Functionalized Trifluoromethylated Cyclohexenes. Katy B. Wilson, Jeffery T. Myers, Hannah S. Nedzbala, Logan A. Combee, Michal Sabat, and W. Dean Harman* J. Am. Chem. Soc., 2017, 139 (33), pp 11401–11412. Highlighted in C&EN

[157] Molybdenum(0) Dihapto-Coordination of Benzene and Trifluorotoluene: The Stabilizing and Chemo-Directing Influence of a CF3 Group. Jeffery T. Myers, Jacob A. Smith, Steven J. Dakermanji, Justin H. Wilde, Katy B. Wilson, Philip J. Shivokevich, and W. Dean Harman* J. Am. Chem. Soc., 2017, 139 (33), pp 11392–11400.

[156] 4-(Dimethylamino)pyridine (DMAP) as an Acid-Modulated Donor Ligand for PAH Dearomatization. Jeffery T. Myers, Steven J. Dakermanji, Timothy R. Chastanet, Philip J. Shivokevich, Laura J. Strausberg, Michal Sabat, William H. Myers, and W. Dean Harman. Organometallics, 2016, DOI: 10.1021/acs.organomet.6b00780

[155] Synthesis of Novel Hexahydroindoles from the Dearomatization of Indoline. Brianna L. MacLeod, Jared A. Pienkos, Katy B.Wilson, Michal Sabat, William H. Myers, and W. Dean Harman. Organometallics, 2016, 35 (3), pp 370–387. ACS Editors' Choice

[154] Synthesis of 2-Substituted 1,2-Dihydronaphthalenes and 1,2-Dihydroanthracenes Using a Recyclable Molybdenum Dearomatization Agent. Jeffery T. Myers, Philip J. Shivokevich, Jared A. Pienkos, Michal Sabat, William H. Myers, and W. Dean Harman, Organometallics, 2015, 34 (14), pp 3648–3657.

[153] Enantioenrichment of a Tungsten Dearomatization Agent Utilizing Chiral Acids. Andrew W. Lankenau, Diana A. Iovan, Jared A. Pienkos, Rebecca J. Salomon, Sisi Wang, Daniel P. Harrison, William H. Myers, and W. Dean Harman. J. Am. Chem. Soc., 2015, 137 (10), pp 3649–3655. Highlighted in C&EN

[152] Stereoselective synthesis of trans-tetrahydroindolines promoted by a tungsten π base. Brianna L. MacLeod, Jared A. Pienkos, Jeffery T. Myers, Michal Sabat, William H. Myers, and W. Dean Harman Organometallics, 2014, 33, 6286–6289.

[151] Double protonation of amino-substituted pyridine and pyrimidine tungsten complexes: friedel–crafts-like coupling to aromatic heterocycles. Jared A. Pienkos, Anne T. Knisely, Brianna L. MacLeod, Jeffery T. Myers, Philip J. Shivokevich, Victor Teran, Michal Sabat, William H. Myers, and W. Dean Harman Organometallics, 2014, 33, 5464–5469.

[150] Tungsten-mediated selective ring opening of vinylcyclopropanes. Pienkos, J. A.; Knisely, A. T.; Liebov, B. K.; Teran, V.; Zottig, V. E.; Sabat, M.; Myers, W. H.; Harman, W. D. Organometallics, 2014, 33, 267–277.

[149] Exploiting the o-Quinodimethane Nature of Naphthalene: Cycloaddition Reactions with η2-Coordinated Tungsten–Naphthalene Complexes. Strausberg, L.; Li, M.; Harrison, D. P.; Myers, W. H.; Sabat, M.; Harman, W. D. Organometallics, 2013, 32, 915–925.

[148] Friedel-crafts ring-coupling reactions promoted by tungsten dearomatization agent. Pienkos, J. A.; Zottig, V. E.; Iovan, D. A.; Li, M.; Harrison, D. P.; Sabat, M.; Salomon, R. J.; Strausberg, L.; Teran, V. A.; Myers, W. H.; Harman, W. D. Organometallics, 2013, 32, 691-703.

[147] [4 + 2] Cyclocondensation reactions of tungsten-dihydropyridine complexes and the generation of tri- and tetrasubstituted piperidines. Harrison, D. P.; Iovan, D. A.; Myers, W. H.; Sabat, M.; Wang, S.; Zottig, V. E.; Harman, W. D.; J. Am. Chem. Soc. 2011, 133, 18378-18387.

[146] Hyperdistorted Tungsten Allyl Complexes and Their Stereoselective Deprotonation to Form Dihapto-Coordinated Dienes. Daniel P. Harrison, Adam C. Nichols-Nielander, Victor E. Zottig, Laura Strausberg, Rebecca J. Salomon, Carl O. Trindle, Michal Sabat, T. Brent Gunnoe, Diana A. Iovan, William H. Myers, and W. Dean Harman, Organometallics, 2011, 30 (9), pp 2587–2597.

[145] Polarization of the pyridine ring: highly functionalized piperidines from tungsten-pyridine complex. Harrison, D. P.; Sabat M.; Myers, W. H.; Harman, W. D. J. Am. Chem. Soc. 2010, 132, 17282-17295.

[144] Epoxidation, Cyclopropanation, and Electrophilic Addition Reactions at the meta Position of Phenol and meta-Cresol. Victor E. Zottig, Michael A. Todd, Adam C. Nichols-Nielander, Daniel P. Harrison, Michal Sabat, William H. Myers, and W. Dean Harman, Organometallics, 2010, 29 (21), pp 4793–4803.

[143] Tungsten-Promoted Pyridine Ring Scission: The Selective Formation of η2-Cyanine and η2-Merocyanine Complexes and Their Derivatives. Daniel P. Harrison, George W. Kosturko, Vijay M. Ramdeen, Adam C. Nichols-Nielander, Sarah J. Payne, Michal Sabat, William H. Myers and W. Dean Harman, Organometallics, 2010, 29 (8), pp 1909–1915.

[142] Single and Double Electrophilic Addition Reactions to the Aniline Ring Promoted by a Tungsten π-Base. Rebecca J. Salomon, Michael A. Todd, Michal Sabat, William H. Myers and W. Dean Harman, Organometallics, 2010, 29 (4), pp 707–709.

[141]Michael−Aldol Ring Closures with Dihapto-Coordinated Pyrrole Complexes and the Synthesis of Tetrahydroindole Cores. Kevin D. Welch, Daniel P. Harrison, Michal Sabat, Emily Z. Hejazi, Brendan T. Parr, Matthew G. Fanelli, Nicole A. Gianfrancesco, Dalsher S. Nagra, William H. Myers and W. Dean Harman, Organometallics, 2009, 28 (20), pp 5960–5967.

[140] Stereo- and Regioselective Nucleophilic Addition to Dihapto-Coordinated Pyridine Complexes. Daniel P. Harrison, Victor E. Zottig, George W. Kosturko, Kevin D. Welch, Michal Sabat, William H. Myers and W. Dean Harman, Organometallics, 2009, 28 (19), pp 5682–5690.

139] Stereoelectronic Effects in Dihapto-Coordinated Complexes of TpW(NO)(PMe3) and Their Manifestation in Diels−Alder Cycloaddition of Arenes. Rebecca J. Salomon, Edward C. Lis,, Jr., Monica U. Kasbekar, Kimberley C. Bassett, William H. Myers, Carl O. Trindle, Michal Sabat and W. Dean Harman, Organometallics, 2009, 28 (16), pp 4724–4734.

[138] Selectfluor-Mediated Dialkoxylation of Tungsten η2-PyridiniumComplexes. Kosturko, G. W.; Harrison, D. P.; Sabat, M.; Myers, W. H.; Harman,W. D. Organometallics 2009, 28, 387-389.

[137] Efficient Synthesis of an η2-Pyridine Complex and aPreliminary Investigation of the Bound Heterocycle's Reactivity. Harrison, D.P.; Welch, K. D.; Nichols-Nielander, A. C.; Sabat, M.; Myers, W. H.; Harman, W.D. J. Am. Chem. Soc. 2008, 130, 16844-16845.

[136] Synthesis of 1-Oxadecalins from Anisole Promoted byTungsten. Lis, E. C.; Salomon, R. J.; Sabat, M.; Myers, W. H.; Harman, W. D. J.Am. Chem. Soc. 2008, 130, 12472-12476.

[135] Tungsten-Promoted Diels−Alder Cycloaddition of Pyridines: Dearomatization of 2,6-Dimethoxypyridine Generates a Potent 2-Azadiene Synthon. George W. Kosturko, Peter M. Graham, William H. Myers, Timothy M. Smith, Michal Sabat and W. Dean Harman, Organometallics, 2008, 27 (17), pp 4513–4522.

[134] Stereoselective Umpolung Tandem Addition ofHeteroatoms to Phenol. Todd, M. A.; Sabat, M.; Myers, W. H.; Smith, T. M.;Harman, W. D. J. Am. Chem. Soc. 2008, 130, 6906-6907.

[133] [2+2] Cycloaddition Reactions with aTungsten-Stabilized 2H-Phenol Todd, M. A.; Sabat, M.; Myers, W. H.; Harman, W.D. J. Am. Chem. Soc. 2007, 129, 11010-11011

[132] Facile Intermolecular Aryl-F Bond Cleavage inthe Presence of Aryl C-H Bonds: Is the η2-Arene Intermediate Bypassed? Liu, W.;Welch, K.; Trindle, C. O.; Sabat, M.; Myers, W. H.; Harman, W. D.Organometallics 2007, 26, 2589-2597

[131] Large-Scale Syntheses of Several Synthons tothe Dearomatization Agent {TpW(NO)(PMe3)} and Convenient Spectroscopic Toolsfor Product Analysis Welch, K. D.; Harrison, D. P.; Lis, E. C., Jr.; Liu, W.;Salomon, R. J.; Harman, W. D.; Myers, W. H. Organometallics 2007, 26, 2791-2794

[130] IsomerizationDynamics and Control of the η2/N Equilibrium for Pyridine Complexes Delafuente,D. A.; Kosturko, G. W.; Graham, P. M.; Harman, W. H.; Myers, W. H.;Surendranath, Y.; Klet, R. C.; Welch, K. D.; Trindle, C. O.; Sabat, M.; Harman,W. D. J. Am. Chem. Soc. 2007, 129, 406-416

[129]Tungsten-Promoted Dearomatization of Heterocycles: Uncovering the Latent2-Azadiene Character of Pyrimidines Surendranath, Y.; Welch, K. D.; Nash, B.W.; Harman, W. H.; Myers, W. H.; Harman, W. D. Organometallics 2006, 25,5852-5853

[128] Osmium(II)-, Rhenium(I)-, andTungsten(0)-Promoted Dipolar Cycloaddition Reactions with Pyrroles: Exploitingthe Azomethine Ylide Character of This Heterocycle Welch, K. D.; Smith, P. L.;Keller, A. P.; Myers, W. H.; Sabat, M.; Harman, W. D. Organometallics 2006, 25,5067-5075

[127] The Uncommon Reactivity ofDihapto-Coordinated Nitrile, Ketone, and Alkene Ligands When Bound to aPowerful π-Base Lis, E. C., Jr.; Delafuente, D. A.; Lin, Y.; Mocella, C. J.;Todd, M. A.; Liu, W.; Sabat, M.; Myers, W. H.; Harman, W. D. Organometallics2006, 25, 5051-5058.

[126] Development ofGroup 6 Dearomatization Agents Ha, Y.; Dilsky, S.; Graham, P. M.; Liu, W.;Reichart, T. M.; Sabat, M.; Keane, J. M.; Harman, W. D. Organometallics, 2006,25, 5184-5187

[125] The role of electrochemistry in the development of π-Basic Tungsten dearomatization agents Surendranath, Y.; Harman, W. D. Dalton Transactions, 2006, 3957-3965

[###] Common Electrophilic Addition Reactions atthe Phenol Ring: The Chemistry of TpW(NO)(PMe3)(η2-phenol) Todd, M. A.;Grachan, M. L.; Sabat, M.; Myers, W. H.; Harman, W. D. Organometallics 2006,25, 3948-3954

[124] Furan [3+2]Dipolar Cycloadditions Promoted by a π-Basic Tungsten Metal Fragment Bassett,K.C.; You, F.; Graham, P.M.; Myers, W.H.; Sabat, M.; Harman, W.D.Organometallics 2006, 25, 435-439

[123] A New Approachto Promoting Sluggish Diels-Alder Reactions: Dihapto-Coordination of the DieneLiu, W.; You, F.; Mocella, C. J.; Harman, W. D. J. Am. Chem. Soc. 2006, 128,1426-1427

[122] Tungsten(0)and Rhenium(I) η2-Pyrrole Complexes:Dearomatization of Pyrroles and their Facile Isomerizations, Protonations, andReductions. Myers, W.H.; Welch, K.D.; Graham, P.M.; Keller, A. Sabat, M.;Trindle, C. O.; Harman, W. D. Organometallics, 2005, 24, 5267

[121] FacileDiels-Alder Reactions with Pyridines Promoted by Tungsten Graham, P. M.;Delafuente, D. A. Liu, W.; Myers, W. H.; Sabat, M.; Harman W. D. J. Am. Chem.Soc. 2005; 127, 10568 Highlighted in C&EN

[120] Rhenium(I)Dihapto-Coordinated Furan Complexes: Converting Furan into a 1,3-Carbon DipoleYou, F.; Friedman, L. A.; Bassett, K. C.; Lin, Y.; Sabat, M. Harman, W. D.Organometallics, 2005; 24, 2903.

[119] Charge donation to and dearomatization of benzeneattending complexation: DFT estimates of binding energies of TpMXO(L) withbenzene, for Tp = hydridotris(pyrazolyl) borate, MXO = MoNO, ReCO, and WNO, andL = ammonia, N-methylimidazole, pyridine, phosphine, methyl isocyanide, andcarbon monoxide Journal of Computational Chemistry 2005, 26, 194-200.

[118] Tungsten(0)η2-Thiophene Complexes: Dearomatization of Thiophene and Its Facile Oxidation,Protonation, and Hydrogenation Delafuente, D. A.; Myers, W. H.; Sabat, M.;Harman, W. D.; Organometallics; 2005; 24; 1876-1885

[117] A NewGeneration of π-Basic Dearomatization Agents, Keane, J. M.; Harman, W. D.;Organometallics; 2005, 24; 1786-1798

[116] Dihapto-Coordinated Amide, Ester, and Aldehyde Complexesand Their Role in Decarbonylation Graham, P. M.; Mocella, C. J.; Sabat, M.;Harman, W. D.; Organometallics, 2005; 24; 911-919.

[115] TransitionMetal-Stabilized Arenium Cations: Protonation of Arenes Dihapto-Coordinated toπ-Basic Metal Fragments Keane, J. M.; Chordia, M. D.; Mocella, C. J.; Sabat,M.; Trindle, C. O.; Harman, W. D.; J. Am. Chem. Soc. 2004, 126, 6806-6815.

[114] CoordinationChemistry and Properties of Unusually π-Basic Molybdenum Fragments Mocella, C.J.; Delafuente, D. A.; Keane, J. M.; Warner, G. R.; Friedman, L. A.; Sabat, M.;Harman, W. D.; Organometallics. 2004, 23; 3772-3779.

[113] Conformationaland Linkage Isomerizations for Dihapto-coordinated Arenes and AromaticHeterocycles: Controlling the Stereochemistry of Ligand Transformations Harman,W. D., Coord. Chem. Rev. 2004, 248, 853-866.

[112] The Dearomatization of Arenes By Dihapto-Coordination Harman, W. D. in Topics in Organometallic Chemistry, vol 7, Transition Metal Arene p Complexes in Organic Synthesis and Catalysis, Kündig, E. P. Ed., Springer: Berlin 2004.

[111] MichaelAddition Reactions with Dihapto-Coordinated Anisoles: Controlling theStereochemistry of the Para and Benzylic Carbons. Smith, P. L. ; Keane, J. M.;Shankman, S. E.; Chordia, M. ; Harman W. D. J. Am. Chem. Soc. 2004, 126(47),15543-15551

[110] Stereoselective Tandem 1,4-Addition Reactionsfor Benzenes: A Comparison of Os(II), Re(I), and W(0) Systems Ding, F.; andHarman, W. D. J. Am. Chem. Soc. 2004, 126(42); 13752-13756

[109] Solid-StateInduced Control of Kinetically Unstable Stereoisomers Keane, J. M. Ding, F.;Sabat, M.; Harman, W. D. J. Am. Chem. Soc. 2004, 126, 785.

[108] Diastereo- andEnantioselective Dearomatization of Rhenium-Bound Naphthalenes Ding, F.;Valahovic, M. T.; Keane, J. M.; Anstey, M. R.; Sabat, M.; Trindle, C. O.;Harman, W. D.; J. Org. Chem. 2004, 69(7), 2257-2267.

[107] Dearomatizationof Benzene, Deamidization of N,N-Dimethylformamide, and a Versatile NewTungsten π Base Graham, P. M.; Meiere, S. H.; Sabat, M.; Harman, W. D.Organometallics 2003, 22, 4364.

[106] Formation ofo-Quinone Methides from Dihapto-Coordinated Phenols and Their ControlledRelease from a Transition Metal to Generate Chromans Stokes, S. M.; Ding, F.;Smith, P. L. ; Keane, J. M. ; Kopach, M. E.; Jervis, R. Sabat, M.; Harman, W.D. Organometallics 2003, 22, 4170.

[105] Stereoselective Aldehyde Addition toRhenium-Coordinated Furans Schiffler, M. A.; Friedman, L. A.; Brooks, B. C.;Sabat, M.; Harman, W. D. Organometallics, 2003, 22, 4966.

[104] Computational Study of Methane Activation by TpRe(CO)2and CpRe(CO)2 with a Stereoelectronic Comparison of Cyclopentadienyl andScorpionate Ligands Bergman, R. G.; Cundari, T. R.; Gillespie, A. M.; Gunnoe,T. B.; Harman, W. D.; Klinckman, T. R.; Temple, M. D.; White, D. P.;Organometallics 2003, 22 (11), 2331.

[103] In Vitro Metabolism of Tolcapone to ReactiveIntermediates: Relevance to Tolcapone Liver Toxicity Smith, K. S.; Smith, P.L.; Heady, T. N.; Trugman, J. M.; Harman, W. D.; Macdonald, T. L.; Chem. Res.Toxicol.; 2003, 16, 123.

[102] ComputationalModeling of Complexes of Pentaammineosmium(II) with Aromatic Ligands, Trindle, C.; Sacks, G.; Harman, W. D. Int. J. Qunat. Chem. 2003, 92, 457.

[101] Rhenium Promoted Diastereo- and EnantioselectiveCyclopentannulation Reactions: Furans as 1,3-Propene Dipoles Friedman, L. A.;You, F.; Sabat, M.; Harman, W. D. J. Am. Chem. Soc. 2003, 125, 14980.

[100] Binding and Activation of Aromatic Molecules by a Molybdenum π-Base Meiere, S. H.; Keane, J. M.; Gunnoe, T. B.; Sabat, M. HarmanW. D. J. Am. Chem. Soc. 2003 125, 2024.

[99] Discriminationof Enantiofaces and Stereoselective Electrophilic Addition Reactions for η2-Pyrrole Complexes Valahovic, M. T.; Myers, W. H.; Harman, W. D.Organometallics 2002, 21, 4581

[98] CycloadditionReactions of Dihapto-Coordinated Furans, Friedman, L. A.; Sabat, M. S.; Harman,W. D. J. Am. Chem. Soc. 2002, 124, 7395.

[97] Tandem 1,4-Addition Reactions with Benzene andAlkylated Benzenes Promoted by Pentaamineosmium(II) Ding, F.; Kopach, M. E.;Sabat, M. Harman, W. D. J. Am. Chem. Soc. 2002, 124, 13080.

[96] Ligand-Modulated Stereo- and Regioselective TandemAddition Reactions of Rhenium-Bound Naphthalene Valahovic, M. T.; Gunnoe, T.B.; Sabat, M. ; Harman, W. D. J. Am. Chem. Soc. 2002, 124, 3309.

[95] A Strategy for the Resolution of a Chiral DearomatizationAgent: {TpRe(CO)(1-methylimidazole)} Coordination of ?-Pinene (Tp =hydridotris(pyrazolyl)borate) Meiere, S. H. Valahovic, M. T. and Harman, W. D.J. Am. Chem. Soc. 2002, 124, 15099.

[94] Evaluation of Muscarinic Agonist-Induced Analgesia inMuscarinic Acetylcholine Receptor Knockout Mice Duttaroy, A.; Gomeza, J.; Gan,J.; Basile, A. S.; Harman, W. D.; Smith, P. L.; Felder,C. C.; Levey, A. I.;Wess, J. Mol. Pharmacol. 2002 62, 1084.

[93] TpRe(L)(Br)2 (Tp = hydridotris(pyrazolyl)borate); L =tBuNC, PMe3, pyridine (py), 1-methylimidazole (MeIm) Electronic Encyclopedia ofReagents for Organic Synthesis, 2002.

[92] Pentaammine(triflato)osmium(III)triflate Electronic Encyclopedia of Reagents for Organic Synthesis, 2002.

[91] Dihapto Coordination of Carboxylic Acid Derivativeswith an Asymmetric Rhenium π-Base: A New Mechanism for Amide Isomerization?Meiere, S. H.; Ding, F. ; Friedman, L. A. Sabat, M.; Harman W. D. J. Am. Chem.Soc. 2002, 124, 13506.

[90] A Facile Diels-Alder Reaction with Benzene: Synthesisof the Bicyclo[2.2.2]octene Skeleton Promoted by Rhenium Chordia, M. D.; Smith,P.L.; Meiere, S. H., Sabat, M; Harman, W. D. J. Am. Chem. Soc. 2001 123, 10756.

[89] Synthetic Applications of the Dearomatization AgentPentaammineosmium(II) Smith, P. L.; Chordia, M. D.; Harman, W. D. Tetrahedron2001, 57, 8203.

[88] Binding Selectivity of Dihapto-Coordinated Olefins,Ketones, and Aldehydes Utilizing the Asymmetric π-Basic Metal Fragment{TpRe(CO)(1-methylimidazole)} (Tp = hydridotris(pyrazolyl)borate) Meiere, S.H.; Harman, W. D. Organometallics 2001, 20, 3876.

[86] MethanolAddition to Dihapto Coordinated Rhenium Complexes of Furan Friedman, L. A.;Harman, W. D. J. Am. Chem. Soc 2001, 123, 8967.

[85] Dihapto Coordination of Aromatic Molecules by theAsymmetric π-Bases {TpRe(CO)(L)} Meiere, S. H.; Brooks, B. C. Gunnoe, T. B.;Carrig, E. H.; Sabat, M. Harman, W. D. Organometallics 2001, 20, 3661.

[84] Ethene Rotationin Chiral Octahedral Rhenium(I) Complexes Friedman, L. A.; Brooks, B. C.;Meiere S. H.; Harman, W. D. Organometallics 2001, 20, 1699.

[83] The Inter- and Intrafacial Linkage Isomerizations ofRhenium Complexes with Aromatic Molecules. Brooks, B. C.; Meiere, S. H.;Friedman, L. A.; Gunnoe, T. B.; Carrig, E.; Harman, W. D. J. Am. Chem. Soc.2001, 123, 3541.

[82] A Promising New Dearomatization Agent: CrystalStructure, Synthesis, and Reactions of the Versatile ComplexTpRe(CO)(1-methylimidazole)(η2-benzene) Scott H. Meiere, Benjamin C. Brooks, T.Brent Gunnoe, Michal Sabat, and W. Dean Harman Organometallics, 2001, 20, 1038.

[81] Dihapto Binding of Aromatic Molecules by π-BasicTransition Metal Complexes: Development of Alternatives to the {Os(NH3)5}2+Fragment, Brooks, B. C.; Gunnoe, T. B.; Harman W. D. Coord.Chem. Rev., 2000,206, 3.

[80] Novel Cyclization Reactions for η2-Furan Complexes,Chen, H.; Caughey, R.; Liu, R. McMills, M.; Rupp, M.; Myers, W. H.; Harman, W.D. Tetraherdron , 2000, 56, 2313.

[79] A Comparison of the Relative Electron DonatingAbilities of Hydridotris(pyrazolyl)borate and Cyclopentadienyl Ligands:Different Interactions with Different Transition Metals Tellers, D. M.; Skoog,S. J.; Bergman, R. G.; Gunnoe, T. B.; Harman, W. D. Organometallics 2000, 19,2428.

[78] {TpRe(bpy)}: ANovel Pentaaminerhenium System That Stabalizes Both High and Low OxidationStates (Tp = Hydridotris(pyrazolyl)borate; bpy =2,2'-dipyridyl), Gunnoe, T. B.;Meiere, S. H.; Sabat, M. Harman, W. D. Inorg. Chem 2000, 39, 6127.

[77] AsymmetricDearomatization of η2-Arene Complexes: Synthesis of StereodefinedFunctionalized Cyclohexenones and Cyclohexenes. Chordia M. D.; Harman, W. D. J.Am. Chem. Soc. 2000, 122, 2725.

[76] Dearomatizationof Naphthalene: Novel Stereoselective Cyclization Reactions Promoted byOsmium(II). Winemiller M. D. ; Harman W. D. J. Org. Chem. 2000, 65,1249.

[75] StereoselectiveDihapto-Binding of Prochiral Aromatic Compounds by {TpRe(CO)(PMe3)}: Synthesis,Characterization, Stability, and Enantiofacial Discrimination (Tp =hydrido(tris)pyrazolylborate) Gunnoe, T. B.; Sabat, M.; Harman, W. D.Organometallics 2000 19, 728-740.

[74] EnantiofacialDiscrimination in Dihapto-Coordination of Aromatic Molecules by the Chiralπ-Base/σ-Lewis Acid TpRe(CO)(PMe3) Gunnoe, T. B. ; Sabat, M. ; Harman, W. D. J.Am. Chem. Soc. 1999, 121, 6499.

[73] Development ofMuscarinic Analgesics Derived from Epibatidine: Role of the M4 Receptor SubtypeEllis, J. L.; Harman, W. D.; Gonzalez, J.; Spera, M. L.; Liu, R.; Shen, T. Y.;Wypij, D. M.; Zuo, F. J. Pharmacol. Exp. Ther. 1999, 288, 1143.

[72] ElectrophilicAdditions to η2-Thiophene Complexes: Synthesis of Novel Thiophenium andThiafulvenium Species Spera, M. L.; Harman, W. D. Organometallics, 1999, 18,2988.

[71] Osmium-MediatedElectrophilic Addition Reactions with Selenophene and the Activation of theSe-C bond. Spera, M. L.; Harman, W. D. Organometallics, 1999, 18, 1559.

[70] Rhenium(I)Terpyridine π-Bases: Reversible η2-Coordination of Ketones, Aldehydes andOlefins in the Terpyridine Plane Helberg, L. E.; Gunnoe, T. B.; Brooks, B. C.;Sabat, M.; Harman, W. D. Organometallics,1999, 18, 573

[69] The Activation and Manipulation of Pyrroles byPentaammineosmium(II) Hodges, L. M. Harman, W. D. in Adv. in NitrogenHeterocycles, Moody, C. J. ed.; JAI Press: Stamford, 1998, Vol 3, pp. 1-44.

[68] Reactions ofTpRe(CO)2(THF) with Aromatic Molecules Gunnoe, T. B.; Sabat, M.; Harman, W. D.,J. Am. Chem. Soc. 1998, 120, 8747.

[67] The Asymmetricπ-bases fac-{Re(dien)(PPh3)(PF3)}+ and fac-{Re(dien)(PPh3)CO)}+: Evidence forFormation of an η2-Furan Complex Brooks, B. C.; Chin, M; Harman, W. D.Organometallics 1998, 17, 4716.

[66] Dearomatizationof Naphthalene: Stereoselective cis-1,4 Tandem Additions Promoted by Osmium(II)Winemiller, M. D.; Harman W. D. J. Am. Chem. Soc. 1998, 120, 7835.

[65] AsymmetricInduction in η2-Arene Complexes of Pentaammineosmium(II) Chordia, M. D.;Harman, W. D. J. Am. Chem. Soc. 1998, 120, 5637.

[64] Activation ofBenzylic Carbons of η2-Arene Complexes: Osmium Promoted Michael-AldolCyclization Reactions of 3-Alkylated Anisoles that Form FunctionalizedDecalins, Kolis, S. P.; Kopach, M. E.; Liu, R.; Harman W. D. J. Am. Chem. Soc.1998, 120, 6205.

[63] StereodefinedTandem Addition Reactions of η2-Arenes: A Versatile Route to FunctionalizedCyclohexenes, Kopach, M. E.; Kolis, S. P.; Liu, R.; Robertson, J. W.; Chordia,M. D.; Harman, W. D. J. Am. Chem. Soc. 1998, 120, 6199.

[62] Dearomatizationof Furan: Elementary Transformations of η2-Coordinated Furan Complexes ofPentaammineosmium(II). Chen, H.; Liu, R.; Myers, W. H.; Harman, W. D. J. Am.Chem. Soc. 1998, 120, 509.

[61] Activation ofStyrenes Towards Diels-Alder Cycloadditions by Osmium(II): Synthesis ofStereodefined Decalin Ring Systems, Kolis, S. P.; Chordia, M. D.; Liu, R.Kopach, M. E.; Harman, W. D. J. Am. Chem . Soc. 1998, 120, 2218.

[60] Reversibleß-Hydride Elimination of Amine Ligands Forming Stable cis-η2-Iminium HydrideOsII Complexes Orth, S. D.; Barrera, J.; Rowe, S. M.; Helberg, L. E. Harman, W.D. Inorganica Chimica Acta 1998, 270, 337.

[59] ElectrophilicAddition to η2-Aldehyde Complexes of Pentaammineosmium(II): The Formation ofFischer Carbyne Complexes via η2-Aldehydium Intermediates Spera, M. L.; Chen,H.; Moody, M. W. Hill, M.M.; Harman, W. D.J. Am. Chem. Soc. 1997,119,1277

[58] A Proposed Mechanism for p-Aminochlonidine Allergenicity Based on its Relative Oxidative Lability Thompson, C. D.; Vachaspati, P. R.; Kolis, S. P.; Gulden, P. H.; Garst, M. E.; Wiese, A.; Munk, S. A.; Harman, W. D.; MacDonald, T. L. Chem. Res. Toxicol., 1997, 10, 1032.

[57] TheCharacterization and Isomerization of η2-Naphthalene and η2-PhenanthreneComplexes of Pentaammineosmium(II) Winemiller, M. D.; Kelsch, B. A.; Sabat, M.;Harman, W. D. Organometallics 1997, 16, 3672.

[56] Electrophile-Promoted Carbon-Sulfur Bond Cleavage in η2-ThiopheneComplexes of Pentaammineosmium(II) Spera, M. L.; Harman, W. D. , J. Am. Chem.Soc. 1997, 119, 8843.

[55] Osmium(II)Dearomatization Agents in Organic Synthesis, Harman, W. D. in Electron TransferReactions, Isied, S. Editor. pp 39-60. American Chemical Society, 1997.

[54] The Activationof Aromatic Molecules with Pentaammineosmium(II) Harman, W. D. Chem. Rev. 1997,97, 1953.

[53] The Preparationof Rhenium(I) and Rhenium(II)-Amine Dinitrogen Complexes and the Characterizationof a Stretched Dihydrogen Species. Chin, R. M.; Dubois, R. H.; Helberg, L. E.Sabat, M.; Bartucz, T. Y.; Lough, A. J. ; Morris, R. M.; Harman, W. D. Inorg.Chem. 1997, 36, 3553.

[52] The Protonationof Unactivated Aromatic Hydrocarbons on Osmium(II): Stabilization of AreniumCations via Unprecedented η2 and η3 Coordination. Winemiller, M. D.; Kopach, M. E.; Harman, W.D. J. Am. Chem Soc. 1997, 119, 2096.

[51] Osmium PromotedElectrophilic Substitution of Anisoles: A Versatile New Method for theIncorporation of Carbon Substituents. Kolis, S. P.; Kopach, M. E.; Liu, R.; Harman, W. D. J. Org. Chem 1997,62, 130.

[50] SequentialElectrophile/Nucleophile Additions for η2-Cyclopentadiene Complexes ofOsmium(II), Ruthenium(II), and Rhenium(I). Spera, M. L.; Chin, R. M.; Winemiller, M. D.;Lopez, K.; Sabat, M.;Harman, W. D. Organometallics 1996, 15, 5447.

[49] The Coordination Chemistry of Low-Valent RheniumPolypyridyl Complexes: Synthesis, Reactivity and Electrochemistry Helberg,L.E.; Orth, S. D.; Sabat, M.; Harman, W. D. Inorganic Chem., 1996, 35, 5584.

[48] The Synthesis of η2-ß-Vinylpyrrole Complexes and TheirConversion to Highly Substituted Indoles. Hodges, L. M.; Spera, M. L.; Moody,M.; Harman, W. D. J. Am. Chem. Soc. 1996, 118, 7117.

[47] DissociativeNucleophilic Substitution of η2-Olefin Complexes via a Novel η2-Vinyl CationIntermediate Chen, H. C.; Harman, W. D. J. Am. Chem. Soc. 1996, 118, 5672.

[46] Dearomatization of Anilines by Coordination toPentaammineosmium(II) Kolis, S. P.; Gonzalez, J.; Bright, L. M.; Harman, W. D.Organometallics, 1996, 15, 245.

[45] Rhenium(I) Coordination Chemistry: The Synthesis,Reactivity and Electrochemistry of Terpyridyl Complexes Helberg, L. E.;Barrera, J.; Sabat, M.; Harman, W. D. Inorg. Chem. 1995, 34, 2033.

[44] η2-ThiopheneComplexes of Pentaammineosmium(II) and their Reversible Protonation to Formη2-2H-Thiophinium Species. Spera, M. L.; Harman, W. D. Organometallics, 1995,14, 1559.

[43] Photochemistryof a Structurally Uncomplicated Phenylcarbyne Complex Trammell, S.; Sullivan,B. P.; Hodges, L. M.; Harman, W. D.; Thorp, H. H.; Smith, S. R. Inorg. Chem.1995, 34, 2791.

[42] The AldolReaction for 2,3-η2-Furan Complexes of Osmium(II): Cyclization Across C(2) andC(4) To Form a New Heterocycle. Liu, R.; Chen, H.; Harman, W. D.Organometallics 1995, 14, 2861.

[41] ß-ElectrophilicAdditions of Pentaammineosmium(II) η2-Pyrrole Complexes Hodges, L. M. Gonzalez,J.; Koontz, J. I. Myers, W. H., Harman, W. D. J. Org. Chem. 1995, 60, 2125.

[40] Osmium-Promoted Dipolar Cycloadditions with Pyrroles: An Efficient Stereoselective Synthesis of 7-Azanorbornanes. Gonzalez, J.; Koontz, J. I.; Myers, W. H.; Hodges, L. M.;Sabat, M.; Nilsson, K. R.; Neely, L. K.; Harman, W. D. J. Am. Chem. Soc, 1995,117, 3405.

[39] The Osmium-Promoted [4+2] Cycloaddition Reaction of Anisole and Characterization ofthe η2-4H-Anisolium Intermediate. Kopach, M. E.; Harman, W. D. J. Org. Chem.1994, 59, 6506

[38] Extension of the Preparation of New Osmium Species to the cis-Tetraammine Moiety Li, Z., Harman,W. D. Lay, P. A. Taube, H. Inorg. Chem. 1994, 33, 3635.

[37] Dearomatization of an η2 Furan Complex and a Survey of its Reactivity. Chen, H.; Hodges, L. M.;Liu, R. Stevens, W. C.; Sabat, M.; Harman, W. D. J. Am. Chem. Soc. 1994, 116,5499.

[36] A Versatile Synthon for the Preparation of Chiral Rhenium(I)-Amine Complexes and theSynthesis of an η2 Benzaldehyde Species. Orth, S. D.; Barrera, J.; Sabat, M.;Harman, W. D. Inorg. Chem. 1994, 33, 3026.

[35] A 2-Azafulviniumand 3-Vinylpyrrole Complex of Osmium(II) from an η2-Pyrrole and its EfficientConversion into a Highly Substituted Indole. Hodges, L. M.; Moody, M.; Harman,W. D. J. Am. Chem. Soc. 1994, 116, 7931.

[34] Novel Michael Additions to Phenols Promoted by Osmium(II): Convenient StereoselectiveSyntheses of 2,4- and 2,5-Cyclohexadienones. Kopach, M. E.; Harman, W. D. J.Am. Chem. Soc. 1994, 116, 6581.

[33] η2-Nitrile and Alkyne Complexes of Tungsten(II) and Their Comparison to η2-Alkynes. Barrera,J. Sabat, M. Harman, W. D. Organometallics, 1993, 12, 4381.

[32] η2-Pyrrole Complexes as Synthons to Alkaloid Derivatives. Hodges, L. M.; Koontz, J. I.;Gonzalez, J.; Myers, W. H.; Harman, W. D. J. Org. Chem. 1993, 58, 4788.

[31] A Novel Dearomatization of Anilines via Complexation to Pentaammineosmium(II):Synthesis of Highly Functionalized 3-Aminocyclohexenes from Anilines. Gonzalez,J.; Sabat, M.; Harman, W. D. J. Am. Chem. Soc. 1993, 115, 8857.

[30] The Direct10ß-Alkylation of ß-Estradiol: Osmium(II) as a Dearomatization Agent. Kopach.M. E.; Kelsh, L. P. Stork, K.; Harman, W. D. J. Am. Chem. Soc. 1993, 115, 5322.

[29] Stability of Pentaammineosmium(II) in Aqueous Solution. Call, J. T.; Hughes, K. A.; Harman,W. D.; Finn, M. G. Inorg. Chem. 1993, 32, 2123.

[28] Coordination Compounds of Pentaaminerhenium. Orth, S. D.; Barrera, J; Sabat, M; Harman, W.D. Inorg. Chem, 1993, 32 , 594.

[27] Carbynes andCarbenes in Coordination Chemistry: A New Class of Pentaammine and TetraammineComplexes of Os(II). Hodges, L. M.; Sabat, M; Harman, W. D. Inorg. Chem. 1993,32, 371.

[26] ß-HydrideElimination for an Amine Ligand and the Microscopic Reverse: The First Report of a cis-Iminium Hydride in Equilibrium with its Amine Precursor. Barrera, J.;Orth, S. D.; Harman, W. D.J. Am. Chem. Soc.1992, 114, 7316.

[25] Tautomerizations, Protonations and Electrophilic Additions ofη2-Coordinated Pyrroles Myers, W. H. Koontz, J. I.; Harman, W. D. J. Am. Chem.Soc. 1992, 114, 5684.

[24] ThePhenol-Cyclohexadienone Equilibrium for Dihapto-Coordinated Arenes. Kopach, M.E.; Harman, W. D.; Hipple, W. G. J. Am. Chem. Soc.1992,114, 1736.

[23] Electrophilic Substitutions on Dihapto-CoordinatedArenes: an Unprecedented Michael Addition for Phenol and Aniline Kopach, M. E.;Gonzalez, J.; Harman, W. D. J. Am. Chem. Soc. 1991, 113, 8972.

[22] Recent Advances in Osmium Chemistry; Harman, W. D.; Lay P. A. in Advances in Inorganic Chemistry, Academic Press, Inc: San Diego. v.37, 1991, 113, 8972.

[21] CrystalStructure of an η2-Acetonitrile Complex of W(II): Acetonitrile as aFour-Electron Donor. Barrera, J.; Sabat, M.; Harman, W. D. J. Am. Chem. Soc.1991, 113, 8178.

[20] EnamineCharacter of a 2,3-η2 Coordinated Pyrrole; Myers, W. H.; Sabat, M.; Harman, W.D. J. Am. Chem. Soc., 1991, 113, 6682.

[19] Allyl Complexesof Pentaammineosmium; Harman, W. D.; Hasegawa, T.; Taube, H. Inorg. Chem. 1991, 30, 453.

[18] Isostructuralη2-Dihydrogen Complexes [Os(NH3)5(H2)]n+ (n=2,3) and the Reduction of Acetone.Harman, W. D.; Taube, H. J. Am. Chem. Soc., 1990, 112, 2261.

[17] CrystalStructure and Pyrolysis of [(Os(NH3)5)2-(η2:η2-μ-C6H6))]4+: Evidence for theFormation of a Stable η2:η6-μ-Arene Complex. Harman, W. D.; Gephart, M.; Taube,H., Inorg. Chem., 1990, 29, 567.

[16] Regio- andStereospecific Selective Hydrogenation of Dihapto Arene Complexes. Harman, W.D. ; Taube, H., J. Am. Chem. Soc., 1990, 112, 2682.

[15] π-HeterocyclicComplexes of Pentaammineosmium(II) and the Metal-Induced Cycloaddition ofPyrrole and Maleic Anhydride. Cordone, R.; Harman, W. D.; Taube, H. J. Am.Chem. Soc., 1989, 111, 5969.

[14] Arene «AlkyneLinkage Isomerizations of Diphenylacetylene on Pentaammineosmium(II). Harman,W. D.; Wishart, J. F.; Taube, H., Inorg. Chem., 1989, 28, 2411

[13] Carbon-HydrogenBond Activation in Novel η2-Bound Cationic Heterocycle Complexes ofPentaammineosmium(II). Cordone, R.; Harman, W. D.; Taube, H. J. Am. Chem. Soc.,1989, 111, 2896.

[12] Alkyne AdditionReactions on Pentaammineosmium(II): The Formation of π-Enol and π-Vinyl Ether Complexes.Harman, W. D.; Dobson, J. C.; Taube, H., J. Am. Chem. Soc. 1989, 111, 3061.

[11] The SelectiveHydrogenation of Benzene to Cyclohexene on Pentaammineosmium(II). Harman, W.D.; Taube, H.J. Am. Chem. Soc., 1988, 110, 7906.

[10] π-Localization ofAromatic Ligands: Formation of Mixed-Metal η2:η2-μ-Arene Complexes ofRuthenium(II) and Osmium(II) Ammines. Harman, W. D.; Taube, H. J. Am. Chem.Soc., 1988, 110, 7555.