Publications in Abstract Form (since joining BSU)
Publications in Abstract Form (since joining BSU)
29. Force Clamp Experiments with Optical Tweezers Confirm Nanomolar Affinity of Doxorubicin to DNA
Jake Palenstijn, Jason Martin, Ioulia F. Rouzina, Mark C. Williams, Thayaparan Paramanathan
Biophysical Journal 125 (4), 219a (2026)
28. Probing Mitoxantrone-DNA Interactions using Optical Tweezers
Mohamed Ali Chadli, Waleed Jabak, Aaron J. Ferreira, Helena Beeloo, Thayaparan Paramanathan
Biophysical Journal 125 (4), 220a (2026)
27. Force-Dependent Binding of DNA Minor Groove Binder Netropsin Measured via Optical Tweezers
Jacob McNally, Youri K. Nabhan, Irbazhusain Shaikh, Michael Morse, Mark C. Williams, Thayaparan Paramanathan
Biophysical Journal 125 (4), 219a (2026)
26. Quantifying the Binding of the Anticancer Drug Mitoxantrone to DNA using Optical Tweezers
Mohamed Ali Chadli, Waleed Jabak, Aaron J. Ferreira, Helena Beeloo, Thayaparan Paramanathan
Biophysical Journal 124 (3), 630a (2025)
25. Quantifying DNA Groove Binding Dynamics of Netropsin using Optical Tweezers
Jacob McNally, Youri K. Nabhan, Irbazhusain Shaikh, Michael Morse, Mark C. Williams, Thayaparan Paramanathan
Biophysical Journal 124 (3), 631a (2025)
24. Probing the Interaction of Doxorubicin with DNA using Optical Tweezers
Jason Martin, Zachary Ells, Brian Dolle, Ioulia F. Rouzina, Mark C. Williams, Thayaparan Paramanathan
Biophysical Journal 124 (3), 630a (2005)
23. Exploring the Interaction of Netropsin and DNA through Constant Force Experiments and Slow Stretching Experiments using Optical Tweezers
Jacob McNally, Youri K. Nabhan, Irbazhusain Shaikh, Thayaparan Paramanathan
Biophysical Journal 123 (3), 225a (2024)
22. Exploring the Binding Kinetics of Chemotherapeutic Mitoxantrone to DNA using Optical Tweezers
Aaron J. Ferreira, Heléna K. Beeloo, Thayaparan Paramanathan
Biophysical Journal 123 (3), 225a-226a (2024)
21. Optical Tweezers Reveal Nanomolar DNA Binding Affinity of Doxorubicin
Jason Martin, Zachary Ells, Brian Dolle, Ioulia F. Rouzina, Mark C. Williams, Thayaparan Paramanathan
Biophysical Journal 123 (3), 225a (2024)
20. Remdesivir Displays Weak Binding to DNA in Optical Tweezers Experiments
Ryan Bauer, Thayaparan Paramanathan
Biophysical Journal 122 (3), 75a (2023)
19. Optical Tweezers Experiments Show Melting the DNA Facilitates the Binding of Minor Groove Binder Netropsin
Irbazhusain Shaikh, Thayaparan Paramanathan
Biophysical Journal 122 (3), 76a (2023)
18. Exploring the Binding of Mitoxantrone to DNA Using Optical Tweezers
Karan Patel, Thayaparan Paramanathan
Biophysical Journal 122 (3), 75a (2023)
17. Optical Tweezers Reveals Anticancer Drug BI-3802 Binds DNA in the Micromolar Range
Jared McAuliffe, Mark C. Williams, Thayaparan Paramanathan
Biophysical Journal 122 (3), 73a (2023)
16. Exploring the Binding of Anticancer Drug BI-3802 to DNA using Optical Tweezers
Jared McAuliffe, Thayaparan Paramanathan
Biophysical Journal 121 (3), 284a (2022)
15. Characterizing DNA Polymerase Kappa's Binding Mechanism to DNA using Optical Tweezers
Joshua Watts, Mark C. Williams, Samer Lone, Thayaparan Paramanathan
Biophysical Journal 121 (3), 477a (2022)
14. Exploring the Doxorubicin-DNA Interactions by DNA Stretching using Optical Tweezers
Zachary Ells, Brian Dolle, Ioulia F Rouzina, Mark C. Williams, Thayaparan Paramanathan
Biophysical Journal 120 (3), 362a (2021)
13. Probing the Binding Mechanism of DNA Polymerase Kappa to DNA using Optical Tweezers
Joshua Watts, Samer Lone,Thayaparan Paramanathan
Biophysical Journal 118 (3) CA (Feb 15-19, 2020)
12. Single-Molecule Studies of Doxorubicin-DNA Interactions using Optical Tweezers
Zachary Ells, Brian Dolle, Mark C. Williams, Thayaparan Paramanathan
Biophysical Journal 118 (3), 222a (2020)
11. Effect of Chirality on the Elastic Properties of DNA-Threading Binuclear Ruthenium Complex
Adam A Jabak, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley, Ioulia F Rouzina, Mark C Williams, Thayaparan Paramanathan
Biophysical Journal 118 (3), 617a (2020)
10. Quantifying Anticancer Drug Doxorubicin Binding to DNA using Optical Tweezers
Zachary Ells, Brian Dolle, Thayaparan Paramanathan
Biophysical Journal 116 (3), 506a (2019)
9. Investigating How Chirality of a Threading Binuclear Ruthenium Complex Affects the DNA Threading Intercalation using Optical Tweezers
Adam A Jabak, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley, Ioulia F Rouzina, Mark C Williams, Thayaparan Paramanathan
Biophysical Journal 116 (3), 140a (2019)
8. Role of Threading Moiety Size and Chirality in Determining the DNA Binding Characteristics of Threading Intercalators
Thayaparan Paramanathan, Andrew Clark, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah J McCauley, Ioulia Rouzina, Mark C Williams
Biophysical Journal 112 (3), 517a (2017)
7. Significance of Steric Bulk in DNA Threading Intercalation Revealed through Force-Dependent Kinetics
Andrew G Clark, Thayaparan Paramanathan, Fredrik Westerlund, Per Lincoln, Micah McCauley, Ioulia Rouzina, Mark C Williams
Biophysical Journal 110 (3), 241a (2016)
6. Role of the Moiety Chirality in Determining the DNA Binding Characteristics of Threading Intercalators
Thayaparan Paramanathan, Nicholas Bryden, Fredrik Westerlund, Per Lincoln, Micah McCauley, Ioulia Rouzina, Mark C Williams
Biophysical Journal 110 (3), 561a (2016)
5. Constructing Dual Beam Optical Tweezers for Undergraduate Biophysics Research
Brian Daudelin, Devon West-Coates, Jon Del'Etoile, Eric Grotzke, Thayaparan Paramanathan
Bulletin of the American Physical Society (2016)
4. Quantifying the DNA Binding Characteristics of Ruthenium based Threading Intercalator Λ Λ -P with Optical Tweezers
Nicholas Bryden, Micah McCauley, Fredrik Westerlund, Per Lincoln, Ioulia Rouzina, Mark Williams, Thayaparan Paramanathan
Bulletin of the American Physical Society (2016)
Thayaparan Paramanathan, Andrew Clark, Fredrick Westerlund, Per Lincoln, Micah J McCauley, Ioulia Rouzina, Mark C Williams
Bulletin of the American Physical Society (2015)
2. The Role of the Threading Moiety in DNA Threading Intercalation by Ruthenium Dimer Complexes
Andrew Clark, Thayaparan Paramanathan, Fredrick Westerlund, Per Lincoln, Micah J McCauley, Ioulia Rouzina, Mark C Williams
Biophysical Journal 108 (2), 398a (2015)
1. Competitor Effect on Molecular Complex Dissociation in the Absence of Ternary Complex Formation
Thayaparan Paramanathan, Daniel Reeves, Larry Friedman, Jane Kondev, Jeff Gelles
Biophysical Journal 108 (2), 164a (2015)
Underlined Authors are Undergraduate Researchers