Teneligliptin Hydrobromide Hydrate
Acotiamide Hydrochloride Hydrate
General Information:
Acotiamide HydrochlorideHydrate,aprokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamide exerts its effect has yet to be fully elucidated, this agent appears to inhibit acetylcholinesterase (AchE), an enzyme responsible for the breakdown of acetylcholine (Ach). Increased Ach concentrations lead to an improvement of gastric emptying and GI motility and eventually to a reduction of dyspepsia symptoms.
Therapeutic Category:
Acotiamide HydrochlorideHydrate falls under the Gastrointestinal Agent.
Benidipine Hydrochloride
General Information:
Benidipine has the formula 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridine-dicarboxylic acid methyl 1-(phenylmethyl)-3-piperidinyl ester hydrochloride. It is a synthetic dihydropyridine derivative that has anti-hypertensive and anti-anginal actions.1 It was originated in Japan by Kyowa Hakko, it is submitted for FDA approval and it is currently available in some Asian countries like India and Japan.
Therapeutic Category:
Benidipinefalls under the Anti –Hypertensive drugs category.
General Information:
PrucaloprideSuccinate is indicated for the treatment of chronic idiopathic constipation (CIC) in adults.CIC is one of the most common chronic functional gastrointestinal disorders worldwide. Prucalopride is a dihydrobenzofurancarboxamide derivative from the benzofurane family that selectively stimulates 5-HT4 receptors and thus, it presents enterokinetic properties.2 The high selectivity of prucalopride allowed further development as it prevented the cardiac adverse reactions observed due to non-target effects of precedent therapies.Prucalopride has been associated with a minimal rate of transient serum enzyme elevations during therapy and has not been implicated in cases of clinically apparent liver injury with jaundice.
Therapeutic Category:
Prucalopride Succinate is a Prokinetic Agent.
Teneligliptin Hydrobromide Hydrate
General Information:
Teneligliptinhydrobromide hydrate has been investigated for the treatment of Type 2 Diabetes Mellitus.This compound belongs to the class of organic compounds known as alpha amino acid amides. These are amide derivatives of alpha amino acids. It is a long-acting, orally bioavailable, pyrrolidine-based inhibitor of dipeptide peptidase 4 (DPP-4), with hypoglycemic activity. Teneligliptin may also reduce plasma triglyceride levels through a sustained increase in GLP-1 levels. It is vast growing molecule in Indian market.
Therapeutic Category.
TeneligliptinHydrobromide Hydrate falls under the Anti-Diabetic Category.
Fimasartan Trihydrate Potassium
General Information:
Fimasartan Potassium is an anti- hypertensive agent comes under the therapeutic category of Anti-hypertensive and consider as an angiotensin II receptor antagonist (ARB) drug employed in the treatment of both hypertension and heart failure. It was also approved by the Korea Food & Drug Administration (KFDA). Antihypertensive capture a huge market size in India as well as in export countries too.It is a pyrimidine-4(3H)-one derivative of losartan and provides a higher potency and stronger efficacy than losartan with a quick onset of antihypertensive effect. Fimasartan is the ninth and latest ARB for the treatment of hypertension Ursodeoxycholic Acid.
Therapeutic Category:
FimasartanTrihydrate Potassium falls under the Anti –Hypertensive drugs category.
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