Embedded Files
Title of the Invention: Modulators (Inhibitors/Activators) of Histone Acetyltransferases:
Product: His group has found the first natural inhibitor of histone acetyltransferase (HAT), anacardic acid, from Cashewnut shell liquid. Using anacardic acid as synthon, our group has synthesized the only known small molecule activator of HAT, specific to p300. These small molecule compounds have been commercialized for academic research purposes
EMD Biosciences Inc., USA: Product: Anacardic acid (HAT inhibitor), CTPB (specific activator of HAT, p300)
Alexis, USA. Product: Anacardic acid (HAT inhibitor) CTPB (specific activator of HAT, p300)
Title of the Invention: Monoclonal Antibodies against NPM1 and Acetylated NPM1, and process Thereof
Product: They have identified the sites of acetylation and generated acetylation site specific antibodies against the modified protein. These antibodies are highly valuable reagents to elucidate the physiological role of this chaperone and also could be useful for diagnostic purposes. Very recently, we have commercialized a set of these antibodies to Merck Millipore and Abcam. Several other companies have also shown interest to avail the license for these antibodies.
Title of the Invention: Inhibition of Histone Acetyltransferases by CTK7A and methods thereof.
Product: This is a HAT inhibitor, which inhibits p300 autoacetylation in mice tumor
Title of the Invention: Activation of p300/CBP Lysine Acetyltransferases Activity.
Product: This is a HAT activator, which enhances autoacetylation of p300 and increases HAT activity
Page updated
Google Sites
Report abuse