Tatsuya MATSUBARA
Postdoctoral Fellow (August 2022 - )
Department of Biomedical Engineering,
Johns Hopkins University School of Medicine
Tatsuya MATSUBARA
Postdoctoral Fellow (August 2022 - )
Department of Biomedical Engineering,
Johns Hopkins University School of Medicine
Last update: Oct.29, 2025
Tatsuya Matsubara, Chris P Miller, Chanhong Min, Chia‐Yi Su, Jong Seob Choi, Chwee Teck Lim, Jude M. Phillip, Joon-wan Kim, Deok-Ho Kim. Topographic Cues Regulate Collective Cell Dynamics in Curved Nano/Microgrooved Tubular Microchannels, Lab on a Chip, 25 (2025) 5255-5267, doi: 10.1039/D5LC00368G
Januka Khanal, Chunxiao Ren, Wenxue Li, Tatsuya Matsubara, Jihoon Lee, Deok-Ho Kim, Jennifer Moliterno, Murat Gunel, Sergei Kotelnikov, Stan Xiaogang Li, Ernest Glukhov, Dima Kozakov, Yansheng Liu, Andre Levchenko. Analysis of the Phosphorylation Networks Characterizing Distinct Phenotypic States in Glioblastoma Cell Populations, bioRxiv, 2025, doi: 10.1101/2025.08.22.671611
Feiyu Yang, Narciso Pavon, Tatsuya Matsubara, Rebecca Sebastian, Beatriz Martinez-Martin, ChangHui Pak, Yubing Sun, Deok-Ho Kim. Spatial Patterning and Transcriptomic Landscapes of Human Neural Organoids by Localized Delivery of Morphogens, SSRN, 2025, doi: 10.2139/ssrn.5185617
Taiki Otomo, Hyunsoo Noh, Tatsuya Matsubara, Deok-Ho Kim, Masashi Ikeuchi, Kazuhiro Yoshida, Joon-wan Kim, Fabrication of Biomimetic Cell Culture Membranes Using Robust and Reusable Nickel Micropillar Molds, BioChip Journal (IF: 5.5, 2023), (2024) doi: 10.1007/s13206-024-00179-7
Taiki Otomo, Tatsuya Matsubara, Masashi Ikeuchi, Kazuhiro Yoshida, Deok-Ho Kim, Joon-wan Kim, A microfluidic device integrated with a stretchable microporous membrane controlled by electro-conjugate fluid, Sensors and Actuators A: Physical (IF: 3.407, 2023), 356 (2023) 114332. doi: 10.1016/j.sna.2023.114332.
C.Y. Su, T. Matsubara, A. Wu, E.H. Ahn, D.H. Kim, Matrix Anisotropy Promotes a Transition of Collective to Disseminated Cell Migration via a Collective Vortex Motion, Advanced Biology (IF: 4.053, 2022), (2023) 2300026. doi.org/10.1002/adbi.202300026.
T. Matsubara, J.S. Choi, D.H. Kim, J.W. Kim, A Microfabricated Pistonless Syringe Pump Driven by Electro‐Conjugate Fluid with Leakless On/Off Microvalves, Small (IF: 13.281, 2022), Volume 18, Issue 15 (2022) 2106221. doi:10.1002/smll.202106221.(Featured as a Front Cover Article)
T. Matsubara, K. Yoshida, J.W. Kim, Active microvalve driven by electro-conjugate fluid jet flow with a hydraulic power source on a chip, Journal of Micromechanics and Microengineering (IF: 1.881, 2020), 30 (2020) 105013. doi:10.1088/1361-6439/aba227.
J.S. Choi, A.S.T. Smith, N.P. Williams, T. Matsubara, M. Choi, J.W. Kim, H.J. Kim, S. Choi, D.H. Kim, Nanopatterned Nafion Microelectrode Arrays for In Vitro Cardiac Electrophysiology, Advanced Functional Materials (IF: 18.808, 2020), 1910660 (2020) 1–10. doi:10.1002/adfm.201910660.
T. Matsubara, H.H. Huynh, K. Yoshida, J.W. Kim, Development of MEMS-fabricated bidirectional ECF (electro-conjugate fluid) micropumps, Sensors and Actuators, A: Physical (IF: 2.904, 2019), 295 (2019) 317–323. doi: 10.1016/j.sna.2019.06.022.
Amarnath Singam, Tatsuya Matsubara, Isaac Berk, Calvinique Lee, Jeremy H. Cho, Deok-Ho Kim, Seungman Park. Nanotopographic Regulation of Cellular Senescence Biomarkers in Mammalian Cells, BMES 2025 Annual Meeting, San Diego, USA, October 2025. (Oral)
Tatsuya Matsubara, Sara Kaufman, Jihyun Hwang, Minjae Do, Byunggik Kim, Jihoon Lee, Hidetoshi Takashima, Deok-Ho Kim. A Strain-Controlled Artery-on-a-Chip Platform for Vascular Mechanobiology and Drug Screening, The 2nd Joint Workshop on Biomedical Engineering between Whiting School of Engineering/Johns Hopkins University and LBB/Science Tokyo, Tokyo, Japan, August 2025. (Poster and presentation)
Tatsuya Matsubara, Sara Kaufman, Jihyun Hwang, Minjae Do, Byunggik Kim, Jihoon Lee, Hidetoshi Takashima, Deok-Ho Kim. A Strain-Controlled Artery-on-a-Chip Platform for Vascular Biomechanics Research, 2025 MPS World Summit, No. 862, Brussels, Belgium, June 2025
D. Lagowala, T. Matsubara, K. Wilmsen, D.-H. Kim, and V.K. Sidhaye. COPD and Extracellular Matrix: How Lung Microenvironmental Changes Influence Progressive Lung Disease Pathology, ATS 2025 International Conference, Am J Respir Crit Care Med2025;211:A3038, San Francisco, United States, May 2025.
Tatsuya Matsubara, Sara Kaufman, Jihyun Hwang, Minjae Do, Jihoon Lee, Hidetoshi Takashima, Byunggik Kim, Mahin Gadkari, Lakshmi Santhanam, Deok-Ho Kim. Engineered Tubular Microchannels for Smooth Muscle Cell Alignment Under Dynamic Cyclic Stretch. 2025 Department of Medicine & Whiting School of Engineering Research Retreat (2025 DOM/WSE Research Retreat) (Internal Symposium of Johns Hopkins University), No. 98, Baltimore, USA, February 2025
Feiyu Yang, Narciso Pavon, Tatsuya Matsubara, Rebecca Sebastian, Beatruz Martinez-Martin, ChangHui Pak, Yubing Sun, Deok-Ho Kim. Dorsal-Ventral and Rostral-Caudal Patterning of Human Brain Organoids using a Localized Passive Diffusion-based Morphogen Gradient Generator. 2025 Department of Medicine & Whiting School of Engineering Research Retreat (2025 DOM/WSE Research Retreat) (Internal Symposium of Johns Hopkins University) No. 103, Baltimore, USA, February 2025
Kenji Yamamoto, Tatsuya Matsubara, Kazuhiro Yoshida, Joon-wan Kim. Study on a Pumping Mechanism by Compressing the Flexible Membranes in Sequence with the Pressure of Electro Conjugate Fluid (ECF) Flow, The 12th JFPS Int. Symp. on Fluid Power HIROSHIMA 2024, Proc. of the 12th JFPS Int. Symp. on Fluid Power HIROSHIMA 2024, 2D1-02, February 2025
Taiki Otomo, Tatsuya Matsubara, Deok-Ho Kim, Masashi Ikeuchi, Kazuhiro Yoshida, Joon-wan Kim, Microdevice Design for Reproducing Dynamic Environments in High-Frequency Oscillatory Ventilation (HFOV), The 8th International Symposium on Biomedical Engineering 2024 (ISBE2024), P2-23, Shizuoka, Japan, December 2024 (Poster) [Poster Award]
Zhanping Ren, Byunggik Kim, Gwangjun Go, Hanwen Wang, Yiguang Zhu, Patarajarin Akarapipad, Andre Loyola, Tatsuya Matsubara, Joseph Criscione, Dong-Ik Lee, Peter Lee, Todd Herron, Deok-Ho Kim, Automated and Scalable Muscle Tissue System with Magnetic-based Functional Evaluation, 2024 BMES Annual Meeting, Baltimore, United States, October 2024 (Poster)
Byunggik Kim, Young-il Kim, Tatsuya Matsubara, Sungmin Hong, and Deok-Ho Kim, Self-adapting stretchable electronics for long-term electrophysiological mapping of human cardiac organoids, Microphysiological Systems World Summit 2024 (MPS World Summit 2024), 214, Seattle, United States, June 2024 (Poster)
Kenji Yamamoto, Tatsuya Matsubara, Kazuhiro Yoshida, Joon-wan Kim, Study on a Pumping Mechanism by Compressing the Flexible Membranes in Sequence with the Pressure of Electro Conjugate Fluid (ECF) flow, The 12th JFPS International Symposium on Fluid Power, C000130, Hiroshima, Japan, October 2024
Taiki Otomo, Tatsuya Matsubara, Deok-Ho Kim, Masashi Ikeuchi, Kazuhiro Yoshida, Joon-wan Kim, Research on microdevices to stretch alveolar cells with high-frequency, International Conference on Precision Engineering and Sustainable Manufacturing 2024 (PRESM2024), A288, Busan, Korea, July 2024
Taiki Otomo, Tatsuya Matsubara, Masashi Ikeuchi, Kazuhiro Yoshida, Joon-wan Kim, Proposal of fabrication method of PDMS porous membrane with Ni micropillars fabricated by MEMS technology, The 8th International Symposium on Biomedical Engineering & International Workshop on Nanodevice Technologies 2023 (ISBE2023),11, Hiroshima, Japan, November 2023 (Poster)
Joon-wan Kim, Yuya Kondo, Taiki Otomo, Akihiro Yasuda, Tatsuya Matsubara, Kazuhiro Yoshida, Study on Droplet Trapping Using an EHD Micropump, International Conference on Precision Engineering and Sustainable Manufacturing 2023 (PRESM2023), W2-FH3, Okinawa Japan, July 2023 (Oral)
T. Matsubara, C.P. Millar, C.Y. Su, J.S. Choi, C.T. Lim, J.W. Kim, D.H. Kim, Engineered tubular microchannel with micro-/nano-patterning for collective cell migration, 2023 Department of Medicine & Whiting School of Engineering Research Retreat (2023 DOM/WSE Research Retreat) (Internal Symposium of Johns Hopkins University) No. 32, Baltimore, USA, February 2023 (Poster and Research Award Presentation) (Awarded as the winner of the Whiting School of Engineering Trainee)
Taiki Otomo, Tatsuya Matsubara, Kazuhiro Yoshida, Deok-Ho Kim, Masashi Ikeuchi, Joon-wan Kim, Research on a microactuator providing stretch stimulation of the alveoli driven by ECF micropump, International Workshop of Piezoelectric Materials and Applications in Actuators (IWPMA2022), 33004, Online, October 2022 (Online Oral)
Tatsuya Matsubara, Kento Kobayashi, Kazuhiro Yoshida, Deok-Ho Kim, Joon-wan Kim, FIB (Focused Ion Beam)-etched metal wire with tunable micropattern, The 6th International Symposium on Biomedical Engineering (ISBE2021), No. 130, Online, December 2021 Online (Video)
Tatsuya Matsubara, Kazuhiro Yoshida, Joon-wan Kim, Development of MEMS-fabricated Bidirectional ECF micropump, International Workshop on Piezoelectric Materials and Applications in Actuators (IWPMA2018), p. 81, Kobe, Japan, September 2018 (Oral)
Tatsuya Matsubara, Joon-wan Kim, Shinichi Yokota, Kazuya Edamura, Proposal of Pumping Aqueous Solution Using ECF Micropump with Diffuser & Nozzle Mechanism, The 6th International Conference on Manufacturing, Machine Design and Tribology (ICMDT2015), TH-PO-18, Okinawa, Japan, April 2015 (Poster)
T. Matsubara, T. Suzuki, M. Hayase, Fabrication of Micro Half Cylindrical Grooves on Quartz Substrate, International Symposium on Technologies against Cancer (ISTC2014), P22 Tokyo, Japan, March 2014 (Poster)
K. Yamamoto, T. Matsubara, K Yoshida, J.W. Kim, Study on fabrication of a peristaltic micropump driven by ECF pressure, The Machine Design and Tribology Division Meeting in JSME (MDT2024), 2B2-2, Oita, Japan, April 2024 (Oral)
Kenji Yamamoto, Tatsuya Matsubara, Kazuhiro Yoshida, Joon-wan Kim, Proposal of a peristaltic micropump driven by an electro-conjugate fluid (ECF), The Japan Society of Mechanical Engineers (JSME) Yamanashi District Conference, B-13, Yamanashi, Japan, November 2023 (Oral)
Y. Kondo, T. Matsubara, K. Yoshida, J.W. Kim, Proposition of droplet trapping device using pressure generated by EHD micropumps, 2022 The Japan Society for Precision Engineering (JSPE) Spring Meeting, Tokyo, Japan, March 2022 (Oral)
Y. Kondo, T. Matsubara, K Yoshida, J.W. Kim, Proposal of droplet-trapping device using the output pressure of EHD micropump, The Japan Society of Mechanical Engineers (JSME) Yamanashi District Conference, Yamanashi, Japan, October 2021 (Oral)
T. Matsubara, J.W. Kim, S. Yokota, K. Edamura, Study on the leftover of water to the fluidic channels in the aqueous solution pumping by ECF jetting, The Machine Design and Tribology Division Meeting in JSME, Toyama, Japan, April 2016 (Oral)
T. Matsubara, J.W. Kim, S. Yokota, K. Edamura, Development of aqueous solution-pumping system by integrating ECF micropumps with diffuser type asymmetric fluid channels, JSME Yamanashi District Conference, No. 150-3, pp. 84-85, Yamanashi, Japan, October 2015 (Oral)
T. Matsubara, J.W. Kim, S. Yokota, K. Edamura, Proposal of Pumping system integrated ECF Micropump with Diffuser & Nozzle Mechanism, JSME Annual Meeting, S1140203, Hokkaido, Japan, September 2015 (Oral)
International MPS Society (iPASS)
Biomedical Engineering Society (BMES)
American Heart Association (AHA)
The Japan Society of Mechanical Engineers (JSPS)
The JSPS2024 Overseas Research Fellowship (2024 - 2026)
The Whiting School of Engineering Trainee Award at the 2023 Department of Medicine & Whiting School of Engineering Research Retreat (2023 DOM/WSE Research Retreat)
The Uehara Memorial Foundation, Postdoctoral Fellowship (2023)
AGL Off campus project (2018-2019) UW
Program for Leading Graduate Schools at the Tokyo Institute of Technology (AGL, Academy for Global Leadership) (2015 - 2019)
J.W. Kim, T. Matsubara, Organ-on-a-chip, Tokyo Institute of Technology, Japanese Patent Application No. 2021-103743 (July 23, 2021), Japanese Unexamined Patent Publication No. 2023-002904 (January 11, 2023), Japanese Patent No. 7717364 (July 25, 2025)
J.W. Kim, T. Matsubara, micropumps, Tokyo Institute of Technology, Japanese Patent Application No. 2021-073017 (April 23, 2021), Japanese Patent Laid-open No. 2022-167294 (December 4, 2022), Japanese Patent No. 7587831 (November 13, 2024)
J.W. Kim, T. Matsubara, microvalves and micropumps, Tokyo Institute of Technology, Japanese Patent Application No. 2021-015852 (February 3, 2021), Japanese Patent Laid-open No. 2022-118970 (August 16, 2022), Japanese Patent No. 7587824 (November 13, 2024)
(Postdoctoral Fellow) August 2022 -
Deok-Ho Kim Laboratory
Department of Biomedical Engineering,
Johns Hopkins University School of Medicine
(Postdoctoral Fellow) July 2020 - July 2022
Lab. for Future Interdisciplinary Research of Science and Technology (FIRST),
Institute of Innovative Research (IIR), Tokyo Institute of Technology
(Visiting Research Scholar) June 2018 - June 2019
Deok-Ho Kim Laboratory
Department of Bioengineering, University of Washington
(Ph.D. in Engineering) April 2016 – September 2020
Yoshida & Kim Laboratory
Department of Mechanical Engineering, Tokyo Institute of Technology
(M.S. in Engineering) April 2014 – March 2016
Yoshida & Kim Laboratory
Department of Mechano-Micro Engineering, Tokyo Institute of Technology
(B.S. in Engineering) April 2010 – March 2014
Hayase Laboratory
Department of Mechanical Engineering, Tokyo University of Science
Tatsuya Matsubara completed his bachelor's in Mechanical Engineering at the Tokyo University of Science, Japan in 2014. He joined the Department of Mechano-Micro Engineering, Interdisciplinary Graduate School of Science and Engineering, Tokyo Institute of Technology in 2014 and received the degree of Master of Engineering in 2016. He was a visiting research scholar in the Department of Bioengineering at the University of Washington from 2018 to 2019. He received a Ph.D. degree in the Department of Mechanical Engineering, at the Tokyo Institute of Technology, Japan in 2020. He is now a postdoctoral fellow at the department of Biomedical Engineering, Johns Hopkins University from August 2022. Currently, his research interest lies in the combination of MEMS and Biotechnology such as dynamic Organ-on-a-chip.