Current
1) NIH/NIGMS # 1R16GM165398-01. Discovery of novel pentacyclic indolocyclopentaphthalazinone PARP1 inhibitors.
Role: Principal Investigator
Budget period: 8/1/2026 – 7/31/2030
2) NIH/NCI # R01-CA259037-01. Tuning PARP-1 retention and release on DNA breaks
Role: Co-Investigator
Budget period: 03/1/2022 – 02/28/2027
Completed
1) NIH/NIGMS # 1SC3GM131971-01. Development of PARP-isoform selective inhibitory chemical probes.
Role: Principal Investigator
Budget period: 7/3/2019 – 6/30/2024
2) UCSF # CA-0133030. Development of dual HDAC/PARP inhibitors.
Role: Principal Investigator
Budget period: 6/1/2019 – 12/31/2024