Virtual Reality vs Phantom Model: Benefits and Drawbacks of

Simulation Training in Neurosurgery. Amir Amini, MD *, Mareen Allgaier, MSc ‡, Sylvia Saalfeld, PhD ‡§

, Klaus-Peter Stein, MD *, Ali Rashidi, MD *, Vanessa M. Swiatek, MD *, I. Erol Sandalcioglu, MD *, Belal Neyazi, MD

Transformers for Colorectal Cancer Segmentation in CT Imaging

International Journal of Computer Assisted Radiology and Surgery

(accepted for publication at IJCARS)

Cross-species variability in lobular geometry and cytochrome P450 hepatic zonation: insights into CYP1A2, CYP2D6, CYP2E1 and CYP3A4

M Albadry, J Küttner, J Grzegorzewski, O Dirsch, E Kindler, R Klopfleisch, ...

Frontiers in Pharmacology 15, 1404938

Assessment of intracranial aneurysm neck deformation after contour deployment

L Spitz, J Korte, F Gaidzik, N Larsen, B Preim, S Saalfeld

International Journal of Computer Assisted Radiology and Surgery, 1-7

Are hemodynamics responsible for inflammatory changes in venous vessel walls? A quantitative study of wall-enhancing intracranial arteriovenous malformation draining veins

J Stahl, LS McGuire, M Rizko, S Saalfeld, P Berg, A Alaraj

Journal of Neurosurgery 1 (aop), 1-10

Computational Flow Diverter Implantation—A Comparative Study on Pre-Interventional Simulation and Post-Interventional Device Positioning for a Novel Blood Flow Modulator

M Thormann, J Stahl, L Marsh, S Saalfeld, N Sillis, A Ding, A Mpotsaris, ... Fluids 9 (3), 55

Deformable 3D/3D CT-to-digital-tomosynthesis image registration in image-guided bronchoscopy interventions

F Saad, R Frysch, S Saalfeld, S Kellnberger, J Schulz, R Fahrig, K Bhadra, ...

Computers in Biology and Medicine, 108199

Advanced Deep Learning for Skin Histoglyphics at Cellular Level

R Kreher, NR Chitti, G Hille, J Hürtgen, M Mengonie, A Braun, T Tüting, ...

BVM Workshop, 66-71

Unveiling rupture risk and clinical outcomes in midline aneurysms: A matched cohort analysis investigating the impact of localization within the anterior or posterior circulation

VM Swiatek, A Amini, CE Sandalcioglu Ortuño, L Spitz, K Hartmann, ...

Neurosurgical Review 47 (1), 76

CT-defined sarcopenia predicts treatment response in primary central nervous system lymphomas

A Surov, HJ Meyer, M Hinnerichs, V Ferraro, V Zeremski, D Mougiakakos, ...

European radiology 34 (2), 790-796

Fusiform versus Saccular Intracranial Aneurysms—Hemodynamic Evaluation of the Pre-Aneurysmal, Pathological, and Post-Interventional State

J Korte, LMM Marsh, S Saalfeld, D Behme, A Aliseda, P Berg

Journal of Clinical Medicine 13 (2), 551

   (link to private copy) 

Image-based hemodynamic simulations for intracranial aneurysms: the impact of complex vasculature

F Gaidzik, J Korte, S Saalfeld, G Janiga, P Berg

International Journal of Computer Assisted Radiology and Surgery, 1-11   (link to private copy) 

Design of a virtual data shelf to effectively explore a large database of 3D medical surface models in VR

M Allgaier, L Spitz, D Behme, A Mpotsaris, P Berg, B Preim, S Saalfeld

International Journal of Computer Assisted Radiology and Surgery 18 (11 …   (link to private copy) 

Livrsono-virtual reality training with haptics for intraoperative ultrasound

M Allgaier, F Huettl, LI Hanke, H Lang, T Huber, B Preim, S Saalfeld, ...

2023 IEEE International Symposium on Mixed and Augmented Reality (ISMAR   (link to private copy) 

Assessment of the flow-diverter efficacy for intracranial aneurysm treatment considering pre-and post-interventional hemodynamics J Stahl, LMM Marsh, M Thormann, A Ding, S Saalfeld, D Behme, P Berg

Computers in Biology and Medicine 156, 106720

 (link to private copy) 

Korte, J., Voß, S., Janiga, G., Beuing, O., Behme, D., Saalfeld, S., & Berg, P. (2023). Is Accurate Lumen Segmentation More Important than Outlet Boundary Condition in Image-Based Blood Flow Simulations for Intracranial Aneurysms?. Cardiovascular Engineering and Technology, 14(5), 617-630.     (link to private copy) 

Stahl, J., Kassem, L., Behme, D., Klebingat, S., Saalfeld, S., and Berg, P. “Fabrication of flexible intracranial aneurysm models using stereolithography 3D printing.” In: Current Directions in Biomedical Engineering. Vol. 9. 1. De Gruyter. 2023, pp. 395–398    (link to private copy) 

Saalfeld, S., Kreher, R., Hille, G., Niemann, U., Hinnerichs, M., Öcal, O., ... & Surov, A. (2023). Prognostic role of radiomics‐based body composition analysis for the 1‐year survival for hepatocellular carcinoma patients. Journal of cachexia, sarcopenia and muscle, 14(5), 2301-2309.    (link to private copy) 

Allgaier, M., Spitz, L., Behme, D., Mpotsaris, A., Berg, P., Preim, B., & Saalfeld, S. (2023). Design of a virtual data shelf to effectively explore a large database of 3D medical surface models in VR. International Journal of Computer Assisted Radiology and Surgery, 1-10.   (link to private copy) 

Fok, W. Y. R., Fieselmann, A., Herbst, M., Eckert, D., Beister, M., Kappler, S., & Saalfeld, S. (2023, April). Learning Patient Rotation Using Synthetic X-ray Images from 3D CT Volumes. In Medical Imaging with Deep Learning, short paper track.

  (link to private copy)

Hille, G., Agrawal, S., Tummala, P., Wybranski, C., Pech, M., Surov, A., and Saalfeld, S. “Joint liver and hepatic lesion segmentation in MRI using a hybrid CNN with transformer layers.” In: Computer Methods and Programs in Biomedicine (2023), p. 107647   (link to private copy)

Thormann, M., Hinnerichs, M., Ordonez, F. B., Saalfeld, S., Perrakis, A., Croner, R., Omari, J., Pech, M., Zamsheva, M., Meyer, H.-J., Wienke, A., and Surov, A. “Sarcopenia is an Independent Prognostic Factor in Patients With Pancreatic Cancer–a Meta-analysis.” In: Academic Radiology 30.8 (2023), pp. 1552–1561  (link to private copy)

Fok, W. Y. R., Fieselmann, A., Herbst, M., Ritschl, L., Kappler, S., & Saalfeld, S. (2023). Deep learning in computed tomography super resolution using multi‐modality data training. Medical Physics. (link to private copy)

Surov, A., Meyer, H. J., Hinnerichs, M., Ferraro, V., Zeremski, V., Mougiakakos, D., Saalfeld, S., Wienke, A., Strobel, A., Wolleschak, D. (2023). CT-defined sarcopenia predicts treatment response in primary central nervous system lymphomas. European Radiology, 1-7. DOIhttps://doi.org/10.1007/s00330-023-09712-y

Geometric Deep Learning Vascular Domain Segmentation, Robert Kreher, Annika Niemann, Libin Kutty, Viju Sudhi, Bernhard Preim, Daniel Behme, Sylvia Saalfeld , Proc. of Bildverarbeitung für die Medizin (BVM), 2023

Automatic Lung Nodule Segmentation in CT Imaging Using an Improved 3D-Res2Unet, Pavan Tummala, Georg Hille, Sylvia Saalfeld, Proc. of Bildverarbeitung für die Medizin (BVM), 2023

Cross-Modality Training Approach for CT Super-Resolution Network, Wai Yan Ryana Fok, Andreas Fieselmann, Magdalena Herbst, Ludwig Ritschl, Marcel Beister, Steffen Kappler, Sylvia Saalfeld, Proc. of Bildverarbeitung für die Medizin (BVM), 2023

Hertel, M., Makvandi, R., Kappler, S., Nanke, R., Bildhauer, P., Saalfeld, S., Radicke, M., Juhre, D., & Rose, G. (2023). Towards a biomechanical breast model to simulate and investigate breast compression and its effects in mammography and tomosynthesis. Physics in Medicine and Biology.

Multimodal exploration of the intracranial aneurysm wall,Annika Niemann, Riikka Tulamo, Eliisa Netti, Bernhard Preim, Philipp Berg, Juan Cebral, Anne Robertson, Sylvia Saalfeld; accepted at IJCARS, 2023 (link to private copy)

 Assessment of the Flow-Diverter Efficacy for Intracranial Aneurysm Treatment Considering Pre- and Post-Interventional Hemodynamics, Janneck Stahl  Laurel Morgan Miller Marsh; Maximilian Thormann; Andreas Ding; Sylvia Saalfeld; Daniel Behme; Philipp Berg; accepted at Computers in Biology and Medicine, 2023 (link to private copy)

A hybrid hierarchical strategy for registration of 7T TOF-MRI to 7T PC-MRI intracranial vessel data, Lena Spitz1,2*, Franziska Gaidzik2,3, Daniel Stucht4, Hendrik Mattern4, Bernhard Preim1,2 and Sylvia Saalfeld1,2, accepted for publication at Int J CARS (2023) (link to private copy) 

Deep learning-based semantic vessel graph extraction for intracranial aneurysm rupture risk management, Niemann, A., Behme, D., Larsen, N., Preim, B., Saalfeld, S., Int J CARS (2023). https://doi.org/10.1007/s11548-022-02818-6, 2023 (link to private copy) 

Saad, F., Frysch, R., Pfeiffer, T., Saalfeld, S., Schulz, J., Georgi, J. C., Nürnberger, Andreas and Lauritsch, Guenter and Rose, Georg (2022, October). Iterative intraoperative digital tomosynthesis image reconstruction using a prior as initial image. In 7th International Conference on Image Formation in X-Ray Computed Tomography (Vol. 12304, pp. 669-674). SPIE. (link to private copy) 

Maximilian Thormann, Mattes Hinnerichs, Felix Barajas Ordonez, Sylvia Saalfeld, Aristoteles Perrakis, Roland Croner, Jazan Omari, Maciej Pech, Marina Zamsheva, Hans-Jonas Meyer, Andreas Wienke, Alexey Surov, Sarcopenia is an Independent Prognostic Factor in Patients With Pancreatic Cancer – a Meta-analysis, Academic Radiology, 2022, https://doi.org/10.1016/j.acra.2022.10.025.(link to private copy) 

Geometric uncertainty in intracranial aneurysm rupture status discrimination: a two-site retrospective study, Florian Hellmeier, Jan Brüning, Philipp Berg, Sylvia Saalfeld, Andreas Spuler, I. Erol Sandalcioglu, Oliver Beuing, Naomi Larsen, Jens Schaller, Leonid Goubergrits: BMJ Open vol. 12 no. 11, e063051, doi: 10.1136/bmjopen-2022-063051 , 2022 (link to private copy) 

Prognostic Impact of Quality and Distribution of Adipose Tissue in Patients With Primary Central Nervous System Lymphoma, Mattes Hinnerichs, Vincenzo Ferraro, Vanja Zeremski, Dimitrios Mougiakakos, Jazan Omari, Maciej Pech, Caroline Bär, Andreas Wienke, Sylvia Saalfeld, Alexandra Strobel, Alexey Surov, Hans Jonas Meyer, Denise Wolleschak:, International Journal of Experimental and Clinical Pathophysiology and Drug Research - In Vivo; vol. 36, no. 6, pp.2828 - 2834, 2022 (link to private copy) 

Spitz, Lena, Allgaier, Mareen, Mpotsaris, Anastasios, Behme, Daniel, Preim, Bernhard and Saalfeld, Sylvia. "Segmentation of Circle of Willis from 7T TOF-MRI data and immersive exploration using VR" Current Directions in Biomedical Engineering, vol. 8, no. 1, 2022, pp. 129-132. https://doi.org/10.1515/cdbme-2022-0033    (link to private copy) 

"Impact of patient-specific inflow boundary conditions on intracranial aneurysm hemodynamics", Stahl, Janneck, Bernovskis, Anna, Behme, Daniel, Saalfeld, Sylvia and Berg, Philipp. Current Directions in Biomedical Engineering, vol. 8, no. 1, 2022, pp. 125-128. https://doi.org/10.1515/cdbme-2022-0032   (link to private copy) 

"Centerline and blockstructure for fast structured mesh generation", Niemann, Annika, Janiga, Gabor, Preim, Bernhard, Behme, Daniel and Saalfeld, Sylvia. Current Directions in Biomedical Engineering, vol. 8, no. 1, 2022, pp. 13-16. https://doi.org/10.1515/cdbme-2022-0004   (link to private copy) 

"Immersive VR training system for clipping intracranial aneurysms", Allgaier, Mareen, Neyazi, Belal, Erol Sandalcioglu, I., Preim, Bernhard and Saalfeld, Sylvia. Current Directions in Biomedical Engineering, vol. 8, no. 1, 2022, pp. 9-12. https://doi.org/10.1515/cdbme-2022-0003  (link to private copy) 

Overcoming Barriers in Neurosurgical Education: A Novel Approach to Practical Ventriculostomy Simulation, Amini, A., Zeller, Y., Stein, K. P., Hartmann, K., Wartmann, T., Wex, C., Mirzaee, E. and Swiatek, V. M. , Saalfeld, S., Haghikia, A., Dumitru, C. A., Sandalcioglu, I.E., Neyazi, B. (2022). Overcoming Barriers in Neurosurgical Education: A Novel Approach to Practical Ventriculostomy Simulation. Operative Neurosurgery, 23(3): 225-234; 2022 (link to private copy) 

VR-based training of craniotomy for intracranial aneurysm surgery, Allgaier, Mareen; Neyazi, Belal; Sandalciogli, I. Erol;Preim, Bernhard; Saalfeld, Sylvia, Int J Comput Assist Radiol Surg. 2022;17(3):449-456. doi: 10.1007/s11548-021-02538-3  (link to private copy) 

Multimodal hemodynamic evaluation of vessel wall enhanced cerebral draining veins for the assessment of arteriovenous malformations, Janneck Stahl, Sylvia Saalfeld, Laura Stone McGuire, Denise Brunozzi, Ali Alaraj, David Hasan, Philipp Berg, Proc. of Conference on Modelling Fluid Flow (CMFF), 2022    (link to private copy) 

Predicting Aneurysm Rupture with Deep Learning on 3D Models. Niemann, A., Preim, B., Beuing, O., and Saalfeld, S. In: Proc. of Bildverarbeitung fur die Medizin (BVM). 2022, pp. 315--320

Multimodal patient-specific modeling of intracranial arteriovenous malformation hemodynamics including feeding artery and draining vein exploration, Janneck Stahl, Sylvia Saalfeld, Ali Alaraj, Oliver Beuing, Naoki Kaneko, Daniel Behme, and Philipp Berg, Prof. of Conf. on Computational and Mathematical Biomedical Engineering (CMBE) 2022 (link to private copy) 

Deep-learning-based Segmentation of Skeletal Muscle Mass in Routine Abdominal CT Scans. Robert Kreher; Mattes Hinnerichs, Bernhard Preim; Sylvia Saalfeld and Alexey Surov, International Journal of Experimental and Clinical Pathophysiology and Drug Research - In Vivo 36(4):1807-1811, 2022 (link to private copy) 

A comparison of input devices for precise interaction tasks in VR-based surgical planning and training. Mareen Allgaier; Vuthea Chheang; Patrick Saalfeld; Vikram Apilla; Tobias Huber; Florentine Huettl; Belal Neyazi; I. Erol Sandalcioglu; Christian Hansen; Bernhard Preim; Sylvia Saalfeld (2022). Computers in Biology and Medicine, 105429.

Self-calibration of C-arm imaging system using interventional instruments during an intracranial biplane angiography, Negar Chabi, Domenico Iuso, Oliver Beuing, Bernhard Preim, Sylvia Saalfeld, International Journal of Computer Assisted Radiology and Surgery IJCARS 17(7):1355-1366, 2022. https://doi.org/10.1007/s11548-022-02580-9

Can Endovascular Treatment of Fusiform Intracranial Aneurysms Restore the Healthy Hemodynamic Environment? - A Virtual Pilot Study, Sylvia Saalfeld, Janneck Stahl, Jana Korte, Laurel M. Miller Marsh, Bernhard Preim, Oliver Beuing, Yurii Cherednychenko, Daniel Behme, Philipp Berg, accepted at Frontiers in Neurology, 2021 (link to private copy) 

Image-based Blood Flow Analysis of Popliteal Artery Aneurysms – an Interdisciplinary Pilot Study, Saalfeld, Sylvia, Mirzaie, Masoud, Fatehpur, Sheila, Korte, Jana and Berg, Philipp. Current Directions in Biomedical Engineering, vol. 7, no. 2, 2021, pp. 891-894. https://doi.org/10.1515/cdbme-2021-2227 

Hemodynamics of anterior communicating artery aneurysms using combined imaging of the anterior circulation Saalfeld, Sylvia, Behme, Daniel, Almizel, Mahmoud and Berg, Philipp. Current Directions in Biomedical Engineering, vol. 7, no. 2, 2021, pp. 887-890. https://doi.org/10.1515/cdbme-2021-2226 

Virtual embolization for treatment support of intracranial AVMs using an interactive desktop and VR application. Ulrike Sprengel, Patrick Saalfeld, Janneck Stahl, Sarah Mittenentzwei, Moritz Drittel, Benjamin Behrendt, Naoki Kaneko, Daniel Behme, Philipp Berg, Bernhard Preim & Sylvia Saalfeld, International Journal of Computer Assisted Radiology and Surgery volume 16, pages 2119–2127 (2021)  [link2]

An interactive tool for identifying patient subgroups based on arbitrary characteristics for medical research,  Lena Spitz, Vanessa M. Swiatek, Belal Neyazi, I. Erol Sandalcioglu, Bernhard Preim, Sylvia Saalfeld, Current Directions in Biomedical Engineering 7(1):43-46, 2021 [bibtex] 

Facial Feature Removal for Anonymization of Neurological Image Data, Fina Gießler (*), Max Thormann, Bernhard Preim, Daniel Behme, Sylvia Saalfeld, Current Directions in Biomedical Engineering 7(1):130-134,  [bibtex] 

A novel tool for monitoring and assessing the outcome of thermal ablations of hepatic lesions, Georg Hille, Felicitas Brokmann, Bennet Hensen, Julian Alpers, Frank Wacker, Sylvia Saalfeld, Current Directions in Biomedical Engineering 7(1):72-75, 2021 [bibtex]

MedMeshCNN - Enabling MeshCNN for Medical Surface Models, Lisa Schneider, Annika Niemann, Oliver Beuing, Bernhard Preim, Sylvia Saalfeld, accepted at Computer Methods and Programs in Biomedicine, 2021 (link to private copy) 

Tissue segmentation in histologic images of intracranial aneurysm wall, Annika Niemann, Anitha Talagini, Pavan Kandapagari, Bernhard Preim, and Sylvia Saalfeld, Interdisciplinary Neurosurgery, 26, 101307, 2021

VICTORIA: VIrtual neck Curve and True Ostium Reconstruction of Intracranial Aneurysms, Philipp Berg, Benjamin Behrendt, Samuel Voß, Oliver Beuing, Belal Neyazi, I. Erol Sandalcioglu, Bernhard Preim Sylvia Saalfeld, Cardiovascular Engineering and Technology, 12(4), 454-465, DOI 10.1007/s13239-021-00535-w

Visual exploration of intracranial aneurysm blood flow adapted to the clinical researcher. Benjamin Behrendt, Wito Engelke, Philipp Berg, Oliver Beuing, Ingrid Hotz, Bernhard Preim, Sylvia Saalfeld. Inproceedings Eurographics 2021 - Dirk Bartz Prize, The Eurographics Association, 2021. 

Distance and Force Visualisations for Improved Simulation of Intracranial Aneurysm Clipping. Mareen Allgaier, Belal Neyazi, Bernhard Preim, Sylvia Saalfeld, International Journal of Computer Assisted Radiology and Surgery, 2021, https://doi.org/10.1007/s11548-021-02413-1 [link2] 

Aneurysm Wall Enhancement Is Associated with Decreased Intrasaccular IL-10 And Morphological Features of Instability. Vanessa M. Swiatek, Belal Neyazi, Jorge A. Roa, Mario Zanaty, Edgar A. Samaniego, Daizo Ishii, Yongjun Lu, I.Erol Sandalcioglu, Sylvia Saalfeld, Philipp Berg, David M. Hasan, Neurosurgery, 2021

Complex wall modelling for hemodynamic simulations of intracranial aneurysms based on histological images. Annika Niemann, Samuel Voß, Riikka Tulamo, Simon Weigand, Bernhard Preim, Philipp Berg, Sylvia Saalfeld, Int J CARS 16, 597–607 (2021). https://doi.org/10.1007/s11548-021-02334-z   

Interactive Visualization of Cerebral Blood Flow for Arteriovenous Malformation Embolisation. Ulrike Sprengel , Patrick Saalfeld , Sarah Mittenentzwei , Moritz Drittel , Belal Neyazi, Philipp Berg , Bernhard Preim , Sylvia Saalfeld, Proc. of Bildverarbeitung für die Medizin (BVM), 36-41, 2021. [bibtex]

Rupture risk assessment for multiple intracranial aneurysms: why there is no need for dozens of clinical, morphological and hemodynamic parameters. Belal Neyazi, Vanessa M. Swiatek, Martin Skalej, Oliver Beuing, Klaus-Peter Stein, Jörg Hattingen, Bernhard Preim, Philipp Berg, Sylvia Saalfeld§ and I. Erol Sandalcioglu§  Therapeutic Advances in Neurological Disorders , 2020, Vol. 13: 1–11 DOI:0.1177/ 1756286420966159 [link2]
§ Both authors contributed equally to this work

Multimodal Validation of Focal Enhancement in Intracranial Aneurysms as an Imaging Marker of a Higher Risk of Rupture. Larsen N, Saalfeld S, Flüh C, Voß S, Hille G, Pravdivtseva M, Berg P.  Abstract 51 @ 55. Jahrestagung der Deutschen Gesellschaft für Neuroradiologie e.V.  (link to private copy)  

The Virtual Reality Flow Lens for Blood Flow Exploration. Benjamin Behrendt, Lisa Piotrowski, Sylvia Saalfeld, Bernhard Preim and Patrick Saalfeld, Proc. of Eurographics Workshop on Visual Computing for Biology and Medicine (EG VCBM), 2020. [bibtex]  

Hemodynamic data assimilation in a subject-specific Circle of Willis geometry. Franziska Gaidzik, Sahani Pathiraja, Sylvia Saalfeld, Daniel Stucht, Oliver Speck, Dominique Thévenin, Gábor Janiga, Clinical Neuroradiology, in print, 2020. https://doi.org/10.1007/s00062-020-00959-2    

Multimodal validation of focal enhancement in intracranial aneurysms as a surrogate marker for aneurysm instability.  Naomi Larsen, Charlotte Flüh, Sylvia Saalfeld, Samuel Voß, Georg Hille, David Trick, Fritz Wodarg, Michael Synowitz, Olav Jansen, Philipp Berg. Neuroradiology (2020). https://doi.org/10.1007/s00234-020-02498-6  (+link to private copy)  

Wall enhancement segmentation for intracranial aneuryms Annika Niemann, Naomi Larsen, Bernhard Preim, Sylvia Saalfeld, 19. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie e.V., in print, 2020. [bibtex]  

Shrinkingtube mesh: Combined mesh generation and smoothing for pathologic vessels Annika Niemann, Bernhard Preim and Sylvia Saalfeld, 19. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie e.V., in print, 2020.    [bibtex]  

Automatic stent and catheter marker detection in X-ray fluoroscopy using adaptive thresholding and classification Negar Chabi, Oliver Beuing, Bernhard Preim and Sylvia Saalfeld, 19. Jahrestagung der Deutschen Gesellschaft für Computer- und Roboterassistierte Chirurgie e.V., in print, 2020.   [bibtex]  

MR vessel wall imaging in intracranial aneurysms – Low flow conditions are correlated with focal wall enhancement, Berg, P., Saalfeld, S., Pravdivtseva, M., Flüh, C., Larsen, N., International Journal Of Artificial Organs, 43(8), 506-555, 08/2020. (link to private copy)  

Automated incisional hernia characterization by non-rigid registration of CT images – a pilot study, Samuel Voß, Philipp D. Lösel, Sylvia Saalfeld, Philipp Berg, Vincent Heuveline, Friedrich Kallinowski, Current Directions in Biomedical Engineering 6(3): 91-94, 2020. [bibtex]

Combining Visual Analytics and Case-Based Reasoning for Rupture Risk Assessment of Intracranial Aneurysms, Lena Spitz, Uli Niemann, Oliver Beuing, Belal Neyazi, Erol Sandalcioglu, Bernhard Preim and Sylvia Saalfeld, International Journal of Computer Assisted Radiology and Surgery, 15(9), p. 1525-1535, https://doi.org/10.1007/s11548-020-02217-9, 2020. [bibtex]         (link to private copy)        

Fokales Wand-Enhancement in intrakraniellen Aneurysmen ist assoziiert mit lokalen hämodynamischen low flow-Verhältnissen und Wandinflammation. Larsen, N., Flüh, C., Saalfeld, S., Voß, S., Hille, G., Jansen, O., & Berg, P. (2020, April). In RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren (Vol. 192, No. S 01, pp. WISS-4). [bibtex]  (link to private copy)        

Response: Letter to the Editor. The missing piece to solve the equation, Philipp Berg, Sylvia Saalfeld, Samuel Voß, Oliver Beuing, Belal Neayzi, Leonid Goubergrits and Gábor Janiga, Journal of Neurosurgery, DOI: https://doi.org/10.3171/2019.9.FOCUS19573   (link to private copy)

VICTORIA - An interactive online tool for the VIrtual neck Curve and True Ostium Reconstruction of Intracranial Aneurysms, Benjamin Behrendt, Samuel Voss, Oliver Beuing, Bernhard Preim, Philipp Berg, Sylvia Saalfeld, Proc. of Bildverarbeitung für die Medizin (BVM), p. 209-214, 2020 [bibtex] (link to private copy) 

Automatic Segmentation of Necrosis Zones after Radiofrequency Ablation of Spinal Metastases, Steffen Johannes, Georg Hille, Mathias Becker, Sylvia Saalfeld, Klaus Tönnies, P. 96 - 102, at Proc. of International Conference of Pattern Recognition Applications and Methods (ICPRAM), February 22-24, 2020, in Valletta, Malta, 2020.   [bibtex]   (link to private copy)      

Interactive exploration of a 3D intracranial aneurysm wall model extracted from histologic slices.  A. Niemann, S. Weigand, T. Hoffmann, M. Skalej, R. Tulamo, B. Preim and S. Saalfeld, International Journal of Computer Assisted Radiology and Surgery 15: 99–107,  https://doi.org/ 10.1007/s11548-019-02083-0 , 2020.        (link to private copy)     

Flow-splitting-based computation of outlet boundary conditions for improved cerebrovascular simulation in multiple intracranial aneurysms, S. Saalfeld, S. Voß, O. Beuing, B. Preim, P. Berg. International Journal of Computer-Assisted Radiology and Surgery, 14(10):1805–1813, https://doi.org/10.1007/s11548-019-02036-7, 2019.  (link to private copy)     

Suitability of Intravascular Imaging for Assessment of Cerebrovascular Diseases. Simon Weigand*, Sylvia Saalfeld*, Thomas Hoffmann, Elisabeth Eppler, Thomas Kalinski, Katja Jachau and Martin Skalej. Journal of Neuroradiology 61(9):1093-1101, 2019. https://doi.org/10.1007/s00234-019-02233-w                       

Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH)---phase II: rupture risk assessment. Berg, P.; Voß, S.; Janiga, G.; Saalfeld, S.; Bergersen, A. W.; Valen-Sendstad, K.; Bruening, J.; Goubergrits, L.; Spuler, A.; Chiu, T. L.; Tsang, A. C. O.; Copelli, G.; Csippa, B.; Pa{\'a}l, G.; Z{\'a}vodszky, G.; Detmer, F. J.; Chung, B. J.; Cebral, J. R.; Fujimura, S.; Takao, H.; Karmonik, C.; Elias, S.; Cancelliere, N. M.;  Najafi, M.; Steinman, D. A.; Pereira, V. M.; Piskin, S.; Finol, E. A. and Pravdivtseva, M.; Velvaluri, P.; Rajabzadeh-Oghaz, H.; Paliwal, N.; Meng, H.; Seshadhri, S.; Venguru, S.; Shojima, M.; Sindeev, S.; Frolov, S.; Qian, Y.; Wu, Y.-A.; Carlson, K. D.; Kallmes, D. F.; Dragomir-Daescu, D.; Beuing, O., International Journal of Computer Assisted Radiology and Surgery, 14(10): 1795-1804, (2019), doi = 10.1007/s11548-019-01986-2,  link to PDF

 A review on the reliability of hemodynamic modeling in intracranial aneurysms: why computational fluid dynamics alone cannot solve the equation, P. Berg, S. Saalfeld, S. Voß, O. Beuing, G. Janiga, Neurosurgical FOCUS 47(1):E15, DOI: 10.3171/2019.4.FOCUS19181, 2019.

 Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): uncertainty quantification of geometric rupture risk parameters. Leonid Goubergrits, Florian Hellmeier, Jan Brüning, Andreas Spuler, Hans-Christian Hege, Samuel Voß, Gabor Janiga, Sylvia Saalfeld, Oliver Beuing, Philipp Berg.BioMedical Engineering OnLine 18(1):35, 2019.DOI: 10.1186/s12938-019-0657-y https://rdcu.be/bsXPk  (link to private copy)

 A Two-Step Risk Assessment Method for Radiofrequency Ablations of Spine Metastases, Nico Merten; Simon Adler; Georg Hille; Magnus Hanses; Mathias Becker; Sylvia Saalfeld; Bernhard Preim, Computers in biology and medicine, 108, 174-181, 2019.     (link to private copy)   

 Floor Map Visualizations of Medical Volume Data. Nico Merten, Sylvia Saalfeld, Bernhard Preim, Proc. of the Winter School of Computer Graphics (WSCG), 49-58, 2019 .            

Comparison of Background Removal Approaches in X-ray Fluoroscopy for Detection of Cerebral Stent Markers. N. Chabi, O. Beuing, B. Preim, S. Saalfeld. Proc. of CURAC, pages 122-127, 2019.          

Treatment outcome validation tool for radiofrequency ablations of spinal metastases. G. Hille, M. Becker, S. Saalfeld and K. Tönnies, Proc. of CURAC, pages 134-139, 2019.         

VR Craniotomy for Optimal Intracranial Aneurysm Surgery Planning Belal Neyazi, Patrick Saalfeld, Philipp Berg, Martin Skalej, Bernhard Preim, Erol Sandalcioglu, Sylvia Saalfeld Proc. of CURAC, 234-239 , 2019

Maps Colors and SUVs for Standardized Clinical Reports, Nico Merten, Philipp Genseke, Bernhard Preim, Michael C. Kreissl, Sylvia Saalfeld, Proc. of CURAC, pages 292-297, 2019

Evolutionary Pathlines for Blood Flow Exploration in Cerebral Aneurysms. Benjamin Behrendt, Wito Engelke, Philipp Berg, Oliver Beuing, Bernhard Preim, Ingrid Hotz, Sylvia Saalfeld, Proc. of Eurographics Workshop on Visual Computing for Biology and Medicine (EG VCBM), 253-263, 2019 + Video; 

Local flow analysis in unruptured middle cerebral artery aneurysms with vessel wall enhancement. Philipp Berg, Sylvia Saalfeld, Benjamin Behrendt, Samuel Voß, Georg Hille,  and Naomi Larsen. Proc. of 6th International Conference on Computational and Mathematical Biomedical Engineering – CMBE2019, to appear, 2019.

Rupture Risk Assessment based on clinical, morphological and hemodynamic parameters in patients with multiple aneurysms. Vanessa M. Swiatek, Belal Neyazi, Sylvia Saalfeld, Philipp Berg, Oliver Beuing, Samuel Voß, Homajoun Maslehaty, Klaus- Peter Stein, Martin Skalej, I. Erol Sandalciolgu, In Proc. of Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), 2019. 

Segmentation of Vertebral Metastases in MRI Using an U-Net like Convolutional Neural Network. Georg Hille, Max Dünnwald, Mathias Becker, Johannes Steffen, Sylvia Saalfeld, Klaus Tönnies. Bildverarbeitung für die Medizin (BVM), p. 31-36, 2019  

Towards Automated Reporting and Visualization of Lymph Node Metastases of Lung Cancer, Nico Merten, Philipp Genseke, Bernhard Preim, Michael C. Kreissl, Sylvia Saalfeld. Bildverarbeitung für die Medizin (BVM), p. 185-190, 2019

 Fluid-structure interaction in intracranial vessel walls: The role of patient-specific wall thickness. Samuel Voss, Sylvia Saalfeld, Thomas Hoffmann, Gábor Janiga, Oliver Beuing and Philipp Berg. Current Directions in Biomedical Engineering 4(1):587-590, 2018. 

Semiautomatic neck curve reconstruction for intracranial aneurysm rupture risk assessment based on morphological parameters. Sylvia Saalfeld, Philipp Berg, Annika Niemann, Maria Luz, Bernhard Preim, Oliver Beuing, International Journal of Computer Assisted Radiology and Surgery 13(11), 1781-1793, https://doi.org/10.1007/s11548-018-1848-x, 2018. 

Multiple Aneurysms AnaTomy CHallenge 2018 (MATCH): Phase I: Segmentation  Berg, P., Voß, S., Saalfeld, S., Janiga, G., Bergersen, A., Valen-Sendstad, K., Bruening, J., Goubergrits, L., Spuler, A., Cancelliere, N.M., Steinman, D.A., Pereira, V.M., Chiu, T.L., Tsang, A.C., Chung, B.J., Cebral, J.R., Cito, S., Pallarès, J., Copelli, G., Csippa, B., Paál, G., Fujimura, S., Takao, H., Hodis, S., Hille, G., Karmonik, C., Elias, S., Kellermann, K., Khan, M.O., Marsden, A.L., Morales, H.G., Piskin S., Finol, E.A., Pravdivtseva, M., Rajabzadeh-Oghaz, H., Paliwal N., Meng, H., Seshadhri, S., Howard, M., Shojima, M., Sugiyama, S., Niizuma, K., Sindeev, S., Frolov, S., Wagner, T., Brawanski, A., Qian, Y., Wu, Y., Carlson, K., Dragomir Daescu, D. and Beuing, O., Cardiovascular Engineering and Technology, DOI: 10.1007/s13239-018-00376-0, 08/2018. 

Real-World Variability in the Prediction of Intracranial Aneurysm Wall Shear Stress: The 2015 International Aneurysm CFD Challenge. Valen-Sendstad, K., Bergersen, A. W., Shimogonya, Y., Goubergrits, L., Bruening, J., Pallares, J., Vernet, A., Piskin, S., Pekkan, K., Geers, A. J., Larrabide, I., Rapaka, S., Mihalef, V., Fu, W., Qiao, A., Jain, K., Roller, S., Mardal, K. A., Kamakoti, R., Spirka, T., Ashton, N., Revell, A., Aristokleous, N., Houston, J. G., Ishida, F., Tsuji, M., Menon, P. G., Browne, L. D., Broderick, S., Shojima, M., Koizumi, S., Barbour, M., Aliseda, A., Morales, H. G., Lefevre, T., Hodis, S., Al-Smadi, Y., Tran, J. S., Marsden, A. L., Vaippummadhom, S., Srinivasan, A., Brown, A. G., Debus; K., Niizuma, K., Rashad, S., M. Owais Khan, M. O., Updegrove, A. R., Shadden, S. C., Cornelissen, B. M., Majoie, C., B., Berg, P., Saalfeld, S., Kono, K., Steinman, D. A., Cardiovascular Engineering and Technology (CVET), 2018, Volume 9, Issue 4, pp 544–564

Generation and Visual Exploration of Medical Flow Data: Survey, Research Trends and Future Challenges, Oeltze-Jafra, S and Meuschke, Monique and Neugebauer, Matthias and Saalfeld, Sylvia and Lawonn, Kai and Janiga, Gabor and Hege, H-C and Zachow, Stefan and Preim, Bernhard, Computer Graphics Forum 38(1): 87-125, 2018.

Virtual Stenting of Intracranial Aneurysms - A Pilot Study for the Prediction of Treatment Success Based on Hemodynamic Simulations, P Berg, S Saalfeld, O Brina, G Janiga, VM Pereira, International Journal of Artificial Organs, p0391398818775521, 2018.  

Explorative Blood Flow Visualization using Dynamic Line Filtering based on Surface Features. Behrendt, B., Berg, P., Beuing, O., Preim, B., Saalfeld, S. Computer Graphics Forum, 37(3): 183-194, https://doi.org/10.1111/cgf.13411 , 2018.

 Vertebral body segmentation in wide range clinical routine spine MRI data, GeorgHille, SylviaSaalfeld, Steffen Serowy, KlausTönnies, Computer Methods and Programs in Biomedicine, 155, 2018,93-99 

18-J Multi-segmental spine image registration supporting image-guided interventions of spinal metastases. Georg Hille, Sylvia Saalfeld, Steffen Serowy, and Klaus Tönnies, Computers in biology and medicine, vol. 102, p. 16–20, 2018.