Research interest
Research interest
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- Numerical simulation of stenosed coronary artery using different CFD models
Coronary heart disease is a primary source of mortality in India and around the globe. There are different types of disease state, but the primary focus of this study is on the disease where there is a narrowing down of the lumen area in the blood vessel. The simulation of the 3D model is done using finite volume-based solver in OpenFOAM. Similarly, the simulation of 1D numerical model is done using Matlab and fortran code.
References
References
Saha, Supratim, T. Purushotham, and K. Arul Prakash. "Comparison of fractional flow reserve value of patient-specific left anterior descending artery using 1D and 3D CFD analysis." International Journal of Advances in Engineering Sciences and Applied Mathematics 11 (2019): 244-253.
Saha, Supratim, T. Purushotham, and K. Arul Prakash. "Numerical and experimental investigations of fractional flow reserve (FFR) in a stenosed coronary artery." E3S Web of Conferences. Vol. 128. EDP Sciences, 2019.
Saha S., Purushotham T., Prakash K.A. (2021) Effect of Occlusion Percentage and Lesion Length on Stenosed Coronary Artery: A Numerical Study. In: Saha S.K., Mukherjee M. (eds) Recent Advances in Computational Mechanics and Simulations. Lecture Notes in Mechanical Engineering. Springer, Singapore.
Saha, S. (2023). Numerical Investigation of Blood Flow Through Stenosed Coronary Artery Using Reduced Order Model. In: Bhattacharyya, S., Benim, A.C. (eds) Fluid Mechanics and Fluid Power (Vol. 2). FMFP 2021. Lecture Notes in Mechanical Engineering. Springer, Singapore.
- Invitro experimental set-up for calculation of FFR in coronary artery
References
Alberto Coccarelli, Supratim Saha, Tanjeri Purushotham, K. Arul Prakash, Perumal Nithiarasu, On the poro-elastic models for microvascular blood flow resistance: an in-vitro validation, Journal of Biomechanics, 2021, 110241, ISSN 0021-9290.
Supratim Saha, T.Purushotham, P.Nithiarasu and K.Arul Prakash ,” In vitro experimental investigation of intermediate coronary lesion using porous terminal impedance”, 6th International conference on computational and mathematical biomedical engineering, June 10-12,2019, Sendai, Japan,ISBN 97-0-9562914-5-5.
- Organ on Chip
Organs-on-chips (OoCs) are systems containing engineered or natural miniature tissues grown inside microfluidic chips. To better mimic human physiology, the chips are designed to control cell microenvironments and maintain tissue-specific functions.
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