Supplementary Information
EFFECTS OF CANNABIDIOL ON SYMPTOMS IN PEOPLE AT CLINICAL HIGH RISK FOR PSYCHOSIS
Supplementary Information
EFFECTS OF CANNABIDIOL ON SYMPTOMS IN PEOPLE AT CLINICAL HIGH RISK FOR PSYCHOSIS
World Psychiatry 2024
Sagnik Bhattacharyya, Elizabeth Appiah-Kusi, Robin Wilson, Aisling O’Neill, Michael Brammer, Steven Williams, Jesus Perez, Matthijs G Bossong,
Philip McGuire
Supplementary Figure 1
Supplementary Table 3. Adverse events* reported at 21 days
*Assessed using the UKU side-effect rating scale1.
Out of 15 patients in the CHR-PLB (6 females) and 15 in the CHR-CBD (6 females) group with tolerability data, no one reported galactorrhoea, gynaecomastia, increased sexual desire, ejaculatory or orgastic dysfunction, dry vagina; only 1 out 6 females in the CHR-CBD group reported menorrhagia and 1 out of 6 females in the CHR-PLB group reported amenorrhoea and 1 out of 9 males in the CHR-CBD group reported erectile dysfunction.
** Chi-square test
REFERENCES:
1. Lingjaerde O, Ahlfors UG, Bech P, Dencker SJ, Elgen K. The UKU side effect rating scale. A new comprehensive rating scale for psychotropic drugs and a cross-sectional study of side effects in neuroleptic-treated patients. Acta Psychiatr Scand Suppl 1987; 334: 1-100.