Super. Complex (short for Supervised Complex) is a computational pipeline to predict protein complexes from protein interaction networks making use of a supervised machine learning strategy.
Super.Complex v3.0 - Interactive results:
Instructions: To view the interactive results, after clicking on the below links, please again click on the different hyperlinks provided on each page. To interact with the visualizations, you can drag or click on the nodes of the graphs of the protein complexes or SARS-COV-2 map.
Super.Complex predictions:
All predicted human protein complexes, including predicted complexes linked to COVID-19. The complexes here are sorted in descending order of the probability of being a complex (score of the Super.Complex machine learning model).
All predicted human protein complexes, ranked by uncharacterized complex score ( Last column - Candidate score for annotated uncharacterized proteins, computed as the normalized product of the number of proteins with high annotation scores and number of proteins with low annotation scores). The second last column (characterization/annotation score of complex) is the weighted sum of the annotation scores of the proteins.
All hu.MAP proteins with their corresponding predicted complexes, sorted in alphabetical order
SARS-COV2 related predictions:
SARS-COV2 map with predicted complex interactions.
SARS-COV2 interacting predicted human protein complexes. The complexes here are sorted in descending order of the no. of proteins in the complex interacting with SARS-COV2.
SARS-COV2 interacting predicted human protein complexes, ranked by uncharacterized complex score ( Last column - Candidate score for annotated uncharacterized proteins, computed as the normalized product of the number of proteins with high annotation scores and number of proteins with low annotation scores). The second last column (characterization/annotation score of complex) is the weighted sum of the annotation scores of the proteins.
SARS-COV2 interacting hu.MAP proteins with their corresponding predicted complexes, sorted in alphabetical order
SARS-COV2 interacting refined CORUM human protein complexes.
SARS-COV2 interacting original CORUM human protein complexes.
SARS-COV2 interacting refined CORUM proteins with their corresponding refined CORUM complexes, sorted in alphabetical order
SARS-COV2 interacting original CORUM proteins with their corresponding refined CORUM complexes, sorted in alphabetical order
Refined CORUM based visualizations:
All refined CORUM human protein complexes, including complexes linked to COVID-19.
All refined CORUM proteins with their corresponding refined CORUM complexes, sorted in alphabetical order
Original CORUM based visualizations:
All original CORUM human protein complexes, including predicted complexes linked to COVID-19. The complexes here are sorted in descending order of the probability of being a complex (score of the Super.Complex machine learning model).
All original CORUM proteins with their corresponding refined CORUM complexes, sorted in alphabetical order
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