Modules Taught
(CBCS Syllabus of Zoology 2018 and NEP 2022, University of Calcutta)
Modules Taught
(CBCS Syllabus of Zoology 2018 and NEP 2022, University of Calcutta)
Molecular Biology, ZOOA-CC1-2-TH
Unit 1: Nucleic Acids
Salient features of DNA, Chargaff’s Rule, Hypo and Hyperchromic shift. Watson and Crick, Model of DNA. RNA types & Function.
Unit 6: Gene Regulation
Regulation of Transcription in eukaryotes: Activators, enhancers, silencer, repressors, miRNA mediated gene silencing. Epigenetic Regulation: DNA Methylation, Histone Methylation & Acetylation.
Unit 8: Molecular Techniques
Western and Southern blot, Northern Blot.
Molecular Biology Lab, ZOOA-CC-1-2-P
Isolation and quantification of genomic DNA from goat liver.
Agarose Gel Electrophoresis.
Cell Biology, ZOOA-CC2-4-TH
Unit 1: Plasma Membrane
Ultra-structure and composition of Plasma membrane: Fluid mosaic model, Transport across membrane - Active and Passive transport, Facilitated transport, Cell junctions: Tight junctions, Gap junctions, Desmosomes.
Unit 7: Cell Signalling
Cell signalling transduction pathways; Types of signalling molecules and receptors (Classification and Example only): RTK & JAK/STAT. Apoptosis.
Cell Biology Lab, ZOOA-CC-2-4-P
Preparation of permanent slide to demonstrate:
a. DNA by Feulgen reaction.
b. Cell viability study by Trypan Blue staining.
Animal Physiology: Controlling and Co-ordinating System, ZOOA-CC3-6-TH
Unit 2: Bone and Cartilage
Structure and types of bones and cartilages, Ossification
Animal Physiology: Controlling and Co-ordinating System Lab, ZOOA-CC3-6-P
Microtomy: Preparation of permanent slide of any five mammalian (Goat/white rat) tissues
Fundamentals of Biochemistry, ZOOA-CC3-7-TH
Unit 2: Lipids
Structure and Significance: Physiologically important saturated and unsaturated fatty acids, Triacylglycerols, Phospholipids, Sphingolipid, Glycolipids, Steroids, Eicosanoids and terpinoids. Lipid metabolism: β-oxidation of fatty acids - a. Palmitic acid {saturated (C 16:0)}, b. Linoleic acid {unsaturated (C 18:2)}; Fatty acid biosynthesis.
Unit 3: Proteins
Protein metabolism: Transamination, Deamination, Urea cycle, Fate of C-skeleton of Glucogenic and Ketogenic amino acids.
Comparative Anatomy of Vertebrates, ZOOA-CC4-8-TH
Unit 4: Circulatory System
General plan of circulation, Comparative account of heart and aortic arches.
Animal Physiology: Life Sustaining Systems, ZOOA-CC4-9-TH
Unit 3: Physiology of Circulation
Structure and functions of haemoglobin; Blood clotting system; Haematopoiesis; Basic steps and
its regulation; Blood groups; ABO and Rh factor.
Immunology, ZOOA-CC4-10-TH
Unit 6: Cytokines
Types, properties and functions of cytokines.
Unit 7: Complement System
Components and pathways of complement activation.
Immunology Lab, ZOOA-CC4-10-P
1. Demonstration of lymphoid organs (by picture).
2. Histological study of Bursa fabricius, spleen, thymus and lymph nodes through slides/photographs.
Principle of Genetics, ZOOA-CC5-12-TH
Unit 1: Mendelian Genetics and its Extension
Principles of inheritance, Incomplete dominance and co-dominance, Epistasis, Multiple alleles, Isoallele (White eye mutations), Pseudoallele (Lozenge Locus) & Cis-trans test for allelism, Lethal alleles, Pleiotropy, Penetrance & Expressivity.
Unit 5: Extra-chromosomal Inheritance
Kappa particle in Paramoecium, Shell spiralling in snail.
Unit 6: Genetic Fine Structure
Complementation test in Bacteriophage (Benzer’s experiment on rII locus).
Principle of Genetics Lab, ZOOA-CC5-12-P
Chi-square analyses for genetic ratio test
DSE1. Endocrinology, ZOOA-DSE(B)-5-1-TH
Unit 3: Peripheral Endocrine Glands
Structure, Hormones and Functions of Thyroid gland, Parathyroid, Adrenal, Pancreas, Ovary and Testis. Disorders of endocrine glands (Diabetes mellitus type I & Type II; Graves’ Disease).
DSE1. Endocrinology Lab, ZOOA-DSE(B)-5-1-P
1. Dissect and display of Endocrine glands in laboratory bred rat.
2. Study of the permanent slides of all the endocrine glands
3. Tissue fixation, embedding in paraffin, microtomy and slide preparation of any endocrine gland.
4. H-E staining of Histological slides.
DSE2. Animal Biotechnology, ZOOA-DSE(A)-6-2-TH
Unit 3: Genetically Modified Organisms
Production of cloned and transgenic animals: Nuclear Transplantation, Retroviral Method, DNA microinjection. Applications of transgenic animals: Production of pharmaceuticals, production of donor organs, knock-out mice.
Unit 4: Culture Techniques and Applications
Animal cell culture, Expressing cloned genes in mammalian cells, Molecular diagnosis of genetic diseases (Cystic fibrosis, Sickle cell anaemia, Thalassemia). Dolly &Polly cloning. Genetically modified economically important animal. Gene Therapy
DSE2. Animal Biotechnology Lab, ZOOA-DSE(A)-6-2-P
1. Genomic DNA isolation from E. coli and Plasmid DNA isolation (pUC 18/19) from E. coli.
Project report on animal cloning & Application & ethical Issues.
NEP Curriculum for Zoology, C.U.
PART I: SEMESTER 1
CORE COURSE-1: Cell Biology
Major/Minor/MDC: CC1-TH
Unit 1: Plasma Membrane
Structure of the Plasma Membrane: Lipid Bilayer (Phospholipids and Cholesterol), Peripheral and Integral Membrane proteins, Glycolipids and Glycoproteins (basic concept of Glycocalyx), Fluid Mosaic Model with special reference to Lipid rafts, Mobility of membrane lipids (FRAP assay) and Mobility of Membrane Proteins (Frye-Edidin Experiment); Cell-cell junctions; Transport through plasma membrane.
Unit 7: Cell Signalling
Signalling system: Modes of cell-cell signalling; Types of Signalling molecules Signalling receptors: Types and example with special reference to regulation of G protein, Adenyl cyclase-cAMP, Enzyme linked Receptors: RTK (ras-raf) and JAK/STAT
Unit 8: Tools and Techniques in Cell Biology
Animal Cell Culture: Primary cell culture and Cell line.