Briefly about us

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We are a chemistry group based at the Institute of Organic Chemistry of the Polish Academy of Sciences of Warsaw, in Poland. Our research group has a fundamental interest in developing innovative synthetic strategies mainly exemplified by sigmatropic rearrangements, transition-metal catalysis, as well as photocatalysis and electrochemical synthesis to streamline previously elusive chemical transformations. Their subsequent implementation in the synthesis of biorelevant compounds and materials is one of the key goals of applied research in the laboratory. We are also engaged in detailed mechanistic studies, as the understanding of new sustainable catalytic concepts will lay a foundation for their applications to the chemical, materials and life-science sectors.

If you are interested to join our group, please see for details here

Saturated Heterocycles as Chiral Auxiliaries

Please have a look on our recent article which will be available soon as a chapter in Chiral Building Blocks in Asymmetric Synthesis: Synthesis and Applications by E. Wojaczyńska & J. Wojaczyński (Eds.);

ISBN: 978-3-527-34946-3 | September 2022 | Wiley-VCH

Chirality — the asymmetric quality found in certain chemical compounds — plays an essential role in our world: chiral compounds can be found in biology, pharmaceutical compounds, agrochemicals, and fragrances. The stereoselective preparation of these complex molecular constructions constitutes a challenge. To this end, modern asymmetric synthesis utilizes a variety of valuable and efficient reagents employed as chiral auxiliaries, metal complexes and organocatalysts in stereoselective catalysis, and enantiopure reactants termed as chiral building blocks.

In Chiral Building Blocks in Asymmetric Synthesis, the achievements in the fields of preparation of and applications of chiral blocks are presented. In doing so, the book comprehensively discusses the important classes of these reactants as the key for the asymmetric synthesis of chiral molecules. As such, it is an indispensable resource about synthetic methods, as well as possible modifications and transformations of important classes of chiral compounds. It also highlights the importance of their use as reactants and auxiliaries in the preparation of more sophisticated molecules or supramolecular systems. [read more...]

Our JACS Au journal cover

The cover devoted to our Perspective Article published in JACS Au concerning on multifunctional heteropentalenes (in collaboration with prof. Daniel T. Gryko)

Abstract: In the broad family of heteropentalenes, the combination of two five-membered heterocyclic rings fused in the [3,2-b] mode has attracted the most significant attention. The relatively straightforward access to these structures, being a consequence of the advances in the last two decades, combined with their physicochemical properties which match the requirements associated with many applications has led to an explosion of applied research. In this Perspective, we will discuss the recent progress of heteropentalenes’ usefulness as an active element of organic light-emitting diodes and organic field-effect transistors. Among the myriad of possible combinations for the different heteroatoms, thieno[3,2-b]thiophenes and 1,4-dihydropyrrolo[3,2-b]pyrroles are subject to the most intense studies. Together they comprise a potent optoelectronics tool resulting from the combination of appreciable photophysical properties, chemical reactivity, and straightforward synthesis. Read more...