June 25th, 2024

New PhD on board!!!

On Tuesday, Dominika defended his Ph.D. thesis devoted to synthesis of N-(2-bromoallyl)allylamines and their transformations to a-amino ketones and g-amino acids While on Friday, June 28th, the Scientific Council of the IOC PAS awarded Dominika the title of doctor of chemical sciences. Congratulations Dominika!!! Great job!!! It as pleasure to work with you. 

March 22nd, 2024

Finally, after few years our comprehensive review on the Kinugasa reaction has been published in prestigious Organic Reactions by Wiley.

A new promo spot of the Institute of Organic Chemistry PAS

Have you seen already the recent spot of our Institute of Organic Chemistry of the Polish Academy of Sciences in Warsaw, Poland? 

If not, carry on!

The Institute of Organic Chemistry of the Polish Academy of Sciences (IOC PAS) is a research unit of category A+ according to the parametrization of the Polish Ministry of Education and Science.

According to the national rankings the IOC PAS is first in the category of scientific institutes conducting research in the field of organic chemistry.

In 2022 in the international ranking of the quality of scientific institutions, SCImago Institutions Rankings (SIR), the IOC PAS took first place in terms of innovation among scientific institutions in Poland and twelfth in the overall SIR ranking.

Marie Skłodowska-Curie in Italy in search of radium

“Madame Skłodowska-Curie arrived alone from Paris to Pisa by train on July 30, 1918, at 3:30 a.m.” This is how the extraordinary journey of the two-time Nobel laureate began, during which she travelled with Italian scientists, investigating natural radiation in thermal waters, fumaroles, and rocks. This research tour is probably the least known journey of the Polish Nobel Prize winner, although it lasted three weeks.

We invite you to see our movie that is the result of cooperation among:

• Scientific Centre of the Polish Academy of Sciences in Rome (Agnieszka Stefaniak-Hrycko),

• Institute of Organic Chemistry of the Polish Academy of Sciences in Warsaw (prof. Marcin Górecki),

• Department of Chemistry and Industrial Chemistry of the University of Pisa (prof. Lorenzo Di Bari, prof. Gaetano Angelici, prof. Valentina Domenici)

• Museum of Maria Skłodowska-Curie in Warsaw (Miłka Skalska)

as part of activities to disseminate and promote science. 

New PhD student on board

Aniket Chaudhari graduated at the Jai Hind College of the Mumbai University. In his master degree research he was focused on the synthesis of salicylaldehyde derivatived water soluble and selective fluorescent chemosensor for the detection of aluminium ion. He was also research assistant at Institute of Chemical Technology (Mumbai, India) where he was conducting the reserch devoted to a TADF materials design and the studies on C-H functionalization reactions.

In our group, Aniket's investigations will be devoted to radical C-H functionalization reactions initiated by nitrogen-centered radical species.

Lecture at University of Łódź

On Friday, March 24th, I had great pleasure to give a lecture devoted to our recent studies on a synthesis and functionalization of allylic systems, particularly alcohols and amines, adidded by photoredox catalysis, electrosynthesis and mechanochemistry.  Many thanks to my friend Prof. Marcin Jasiński for kind invitation and wonderful hospitality.

Dominika's paper devoted to synthesis of amino ketones via cross-coupling and visible light mediated oxidative cleavage was just accepted in Advanced Synthesis & Catalysis

Our new article in Adv. Synth. Catal

We report a convenient two-step approach to α-amino ketones involving cross-coupling and oxidative cleavage. The cross-coupling reaction creates a divergent functionalization of the molecular platform, e.g., N-(2-bromoallyl)amine, whereas the oxidative cleavage establishes the carbonyl functionality. This strategy allows for an introduction of aryl/heteroaryl and alkyl groups, either through the Suzuki reaction with arylboronic acids or via dual photoredox/Ni-catalysis to install alkyl groups. The oxidative cleavage to provide target α-amino ketones can be realized either by treating with ozone or by employing milder photochemical protocols involving oxygen or photoexcited nitroarenes as oxidants. We successfully demonstrate the scalability of this protocol, which, together with its simplicity, generality, and its ability to provide access to amino ketones that are inaccessible through other strategies, highlights the suitability of this approach for a wide range of applications across the different chemical sciences. 

High School students in our group

Mikołaj Warda has joined our group for a month intership. Mikołaj is a student of The Staszic High School in Warsaw and a passionate of an organic chemistry. In our lab he is working on a synthesis of 4-substituted 1,4-dipyridines which will be employed as the alkyl radical precursors for a photoredox coupling reactions. He also works on the synthesis of phtalnitrile based  dyes, which serve as  the organic photocatalysts.

Recently, Mikołaj took the 3rd place in qualification for the 3rd stage of the 69th National Chemical Olympiad. We are very proud and keep our finger crossed for the further sucesses