The ever accelerating process of urbanization enables modern people to live conveniently in a fully-connected world, urging for rich and real-time physiological and psychological healthcare services. To this end, Smart Sensing and Affective Computing (S2AC) lab aims to integrate promising tools from diversified fields like Signal Processing (SP), Artificial Intelligence (AI), Machine Learning (ML) and Hardware Design (HD) to develop innovative technologies and systems for smart ambient sensing and context understanding with a focus on pervasive computing and affective computing.