Publications
71. Eum, D. Y.; Jeong, M.; Park, S. Y.; Kim, J.; Jin, J.; Shim, J. W.; Lee, S. R.; Park, S. J.; Heo, K.; Yun, H.; Choi, Y. J. AM-18002, a derivative of natural anmindenol A, enhances radiosensitivity in mouse breast cancer cells. Plos One, 2024, 19, e0296989.
71. Eum, D. Y.; Jeong, M.; Park, S. Y.; Kim, J.; Jin, J.; Shim, J. W.; Lee, S. R.; Park, S. J.; Heo, K.; Yun, H.; Choi, Y. J. AM-18002, a derivative of natural anmindenol A, enhances radiosensitivity in mouse breast cancer cells. Plos One, 2024, 19, e0296989.
70. Eum, D. Y.; Lee, C.; Tran, C. S.; Park, S. Y.; Jeong, M. S.; Jin, Y.; Shim, J. W.; Lee, S. R.; Koh, M.; Vasileva, E. A.; Mishchenko, N. P.; Park, S. J.; Choi, S. H.; Choi, Y. J.; Yun, H.; Heo, K. Regulatory role of Echinochrome A in cancer-associated fibroblast-mediated lung cancer cell migration. Toxicol. Res., 2024, In press.
70. Eum, D. Y.; Lee, C.; Tran, C. S.; Park, S. Y.; Jeong, M. S.; Jin, Y.; Shim, J. W.; Lee, S. R.; Koh, M.; Vasileva, E. A.; Mishchenko, N. P.; Park, S. J.; Choi, S. H.; Choi, Y. J.; Yun, H.; Heo, K. Regulatory role of Echinochrome A in cancer-associated fibroblast-mediated lung cancer cell migration. Toxicol. Res., 2024, In press.
69. Lee, D. Y.; Kim, J.; Lee, G. S.; Park, S.; Song, J.; Lee, B. S.; Lee, S. R.; Kim, K. H.; Kim, C. S. Characterization of Chemical Interactions between Clinical Drugs and the Oral Bacterium, Corynebacterium matruchotii, via Bioactivity-HiTES. ACS Chem. Biol., 2024, 19, 973-980.
69. Lee, D. Y.; Kim, J.; Lee, G. S.; Park, S.; Song, J.; Lee, B. S.; Lee, S. R.; Kim, K. H.; Kim, C. S. Characterization of Chemical Interactions between Clinical Drugs and the Oral Bacterium, Corynebacterium matruchotii, via Bioactivity-HiTES. ACS Chem. Biol., 2024, 19, 973-980.
68. Lee, B. S.; Kim, H.; Baek, J.; Ryoo, R.; Lee, S. R.; Kim, K. H. Determination of the Absolute Configuration of Secondary Alcohols in a Compound Mixture via the Application of Competing Enantioselective Acylation Coupled with LC/MS Analysis. Pharmaceuticals, 2024, 16, 3.
68. Lee, B. S.; Kim, H.; Baek, J.; Ryoo, R.; Lee, S. R.; Kim, K. H. Determination of the Absolute Configuration of Secondary Alcohols in a Compound Mixture via the Application of Competing Enantioselective Acylation Coupled with LC/MS Analysis. Pharmaceuticals, 2024, 16, 3.
67. Lee, B. S.; Lee, Y. Y.; Lee, S. R.; Jang, Y. S.; Ryoo, R.; Park, W.; Kim, S. N.; Lee, S.; Park, C. G.; Kim, K. H. Isolation of Macrocyclic Trichothecene Mycotoxins from the Lethal Toxic Mushroom Podostroma cornu-damae and Their Cytotoxic Activities. Separations, 2024, 11, 65.
67. Lee, B. S.; Lee, Y. Y.; Lee, S. R.; Jang, Y. S.; Ryoo, R.; Park, W.; Kim, S. N.; Lee, S.; Park, C. G.; Kim, K. H. Isolation of Macrocyclic Trichothecene Mycotoxins from the Lethal Toxic Mushroom Podostroma cornu-damae and Their Cytotoxic Activities. Separations, 2024, 11, 65.
66. Han, E.; Lee, S. R.; Townsend, A. Craig; Seyedsayamdost, R. M. Targeted Discovery of Cryptic Enediyne Natural Products via FRET-coupled High-Throughput Elicitor Screening. ACS Chem. Biol., 2023, 18, 1854-1862.
66. Han, E.; Lee, S. R.; Townsend, A. Craig; Seyedsayamdost, R. M. Targeted Discovery of Cryptic Enediyne Natural Products via FRET-coupled High-Throughput Elicitor Screening. ACS Chem. Biol., 2023, 18, 1854-1862.
65. Hur, J. Y.; Jeong, E.; Kim, Y. C.; Lee, S. R. Strategies for natural product discovery by unlocking cryptic biosynthetic gene clusters in fungi. Separations, 2023, 10, 333.
65. Hur, J. Y.; Jeong, E.; Kim, Y. C.; Lee, S. R. Strategies for natural product discovery by unlocking cryptic biosynthetic gene clusters in fungi. Separations, 2023, 10, 333.
64. Nguyen, Q. N.; Lee, S. R.; Kim, B.; Hong, J. H.; Jang, Y. S.; Lee, D. E.; Pang, C.; Kim, K. H.; Kang, K. S. Estrogenic Activity of 4-Hydroxy-Benzoic Acid from Acer tegmentosum via Estrogen Receptor α-Dependent Signaling Pathways. Plants, 2022, 11, 3387.
64. Nguyen, Q. N.; Lee, S. R.; Kim, B.; Hong, J. H.; Jang, Y. S.; Lee, D. E.; Pang, C.; Kim, K. H.; Kang, K. S. Estrogenic Activity of 4-Hydroxy-Benzoic Acid from Acer tegmentosum via Estrogen Receptor α-Dependent Signaling Pathways. Plants, 2022, 11, 3387.
63. Han, E.; Lee, S. R.; Hoshino, S.; Seyedsayamdost, R. M. Targeted discovery of cryptic metabolites with antiproliferative activity. ACS Chem. Biol. 2022, 17, 3121-3130.
63. Han, E.; Lee, S. R.; Hoshino, S.; Seyedsayamdost, R. M. Targeted discovery of cryptic metabolites with antiproliferative activity. ACS Chem. Biol. 2022, 17, 3121-3130.
62. Lee, D.; Yu, J. S.; Ha, J. W.; Lee, S. R.; Lee, B. S.; Kim, J. C.; Kim, J. K.; Kang, K. S.; Kim, K. H. Antitumor potential of withanolide glycosides from ashwagandha (Withania somnifera) on apoptosis of human hepatocellular carcinoma cells and tube formation in human umbilical vein endothelial cells. Antioxidants. 2022, 11, 1761.
62. Lee, D.; Yu, J. S.; Ha, J. W.; Lee, S. R.; Lee, B. S.; Kim, J. C.; Kim, J. K.; Kang, K. S.; Kim, K. H. Antitumor potential of withanolide glycosides from ashwagandha (Withania somnifera) on apoptosis of human hepatocellular carcinoma cells and tube formation in human umbilical vein endothelial cells. Antioxidants. 2022, 11, 1761.
61. Li, Y.; Lee, S. R.; Han, E.; Seyedsayamdost, R. M. Momomycin, an antiproliferative cryptic metabolite from the oxytetracycline producer Streptomyces rimosus. Angew. Chem. Int. Ed. 2022, 61, e202208573.
61. Li, Y.; Lee, S. R.; Han, E.; Seyedsayamdost, R. M. Momomycin, an antiproliferative cryptic metabolite from the oxytetracycline producer Streptomyces rimosus. Angew. Chem. Int. Ed. 2022, 61, e202208573.
60. Lee, S. R.; Seyedsayamdost, R. M. Induction of diverse cryptic fungal metabolites by steroids and channel blockers. Angew. Chem. Int. Ed. 2022. 61, e202204519.
60. Lee, S. R.; Seyedsayamdost, R. M. Induction of diverse cryptic fungal metabolites by steroids and channel blockers. Angew. Chem. Int. Ed. 2022. 61, e202204519.
59. Lee, S. R.; Schalk, F.; Schwitalla, J. W.; Guo, H.; Yu, J. S.; Song, M. Y.; Jung, W. H.; de Beer, Z. W.; Beemelmanns, C.; Kim, K. H. GNPS-guided discovery of madurastatins A1, A2, E1, F, and G1, siderophores from the termite-associated Actinomadura sp. RB99. Chem. Eur. J. 2022, 28, e202200612.
59. Lee, S. R.; Schalk, F.; Schwitalla, J. W.; Guo, H.; Yu, J. S.; Song, M. Y.; Jung, W. H.; de Beer, Z. W.; Beemelmanns, C.; Kim, K. H. GNPS-guided discovery of madurastatins A1, A2, E1, F, and G1, siderophores from the termite-associated Actinomadura sp. RB99. Chem. Eur. J. 2022, 28, e202200612.
58. Lee S. R.; Lee B. S.; Yu J. S.; Kang H.; Yoo M. J.; Kim S.; Kim J. K.; Kim J. C.; Kim K. H. Identification of anti-adipogenic withanolides from the roots of Indian ginseng (Withania somnifera). J. Ginseng Res. 2022, 46, 357-366.
58. Lee S. R.; Lee B. S.; Yu J. S.; Kang H.; Yoo M. J.; Kim S.; Kim J. K.; Kim J. C.; Kim K. H. Identification of anti-adipogenic withanolides from the roots of Indian ginseng (Withania somnifera). J. Ginseng Res. 2022, 46, 357-366.
57. Park, J. D.; Li, Y.; Moon, K.; Han, J. E.; Lee, S. R.; Seyedsayamdost, R. M. Structural Elucidation of Cryptic Algaecides in Marine Algal-Bacterial Symbioses by NMR Spectroscopy and MicroED. Angew. Chem. Int. Ed. 2022. 61, e202114022.
57. Park, J. D.; Li, Y.; Moon, K.; Han, J. E.; Lee, S. R.; Seyedsayamdost, R. M. Structural Elucidation of Cryptic Algaecides in Marine Algal-Bacterial Symbioses by NMR Spectroscopy and MicroED. Angew. Chem. Int. Ed. 2022. 61, e202114022.
56. Lee, S.; Yu, J. S.; Lee, S. R.; Kim, Ki Hyun. Non-peptide secondary metabolites from poisonous mushrooms: overview of chemistry, bioactivity, and biosynthesis. Nat. Prod. Rep. 2022, 39, 512-559
56. Lee, S.; Yu, J. S.; Lee, S. R.; Kim, Ki Hyun. Non-peptide secondary metabolites from poisonous mushrooms: overview of chemistry, bioactivity, and biosynthesis. Nat. Prod. Rep. 2022, 39, 512-559
55. Lee, D.; Lee S. R.; Park, B. J.; Song, J. H.; Kim, J. K.; Ko, Y.; Kang, K. S.; Kim, K. H. Identification of Renoprotective Phytosterols from the Fruits of Mulberry (Morus alba) against Cisplatin-induced Cytotoxicity in LLC-PK1 Kidney Cells. Plants, 2021, 10, 2481.
55. Lee, D.; Lee S. R.; Park, B. J.; Song, J. H.; Kim, J. K.; Ko, Y.; Kang, K. S.; Kim, K. H. Identification of Renoprotective Phytosterols from the Fruits of Mulberry (Morus alba) against Cisplatin-induced Cytotoxicity in LLC-PK1 Kidney Cells. Plants, 2021, 10, 2481.
54. Lee, B. S.; Yoo, M. J.; Kang, H.; Lee, S. R.; Kim, S.; Yu, J. S.; Kim, J. C.; Jang, T. S.; Pang, C.; Kim, K. H. Withasomniferol D, a New Anti-adipogenic Withanolide from the Roots of Ashwagandha (Withania somnifera). Pharmaceuticals 2021, 14, 1017.
54. Lee, B. S.; Yoo, M. J.; Kang, H.; Lee, S. R.; Kim, S.; Yu, J. S.; Kim, J. C.; Jang, T. S.; Pang, C.; Kim, K. H. Withasomniferol D, a New Anti-adipogenic Withanolide from the Roots of Ashwagandha (Withania somnifera). Pharmaceuticals 2021, 14, 1017.
53. Lee, D.; Lee, S. R.; Kang K. S.; Kim, K. H. Bioactive Phytochemicals from Mulberry: Potential Anti-inflammatory Effects in Lipopolysaccharide-stimulated RAW 264.7 Macrophages. Int. J. Mol. Sci. 2021, 22, 8120
53. Lee, D.; Lee, S. R.; Kang K. S.; Kim, K. H. Bioactive Phytochemicals from Mulberry: Potential Anti-inflammatory Effects in Lipopolysaccharide-stimulated RAW 264.7 Macrophages. Int. J. Mol. Sci. 2021, 22, 8120
52. Lee, S. R.; Guo, H.; Yu, J. S.; Park, M.; Dahse, H. M.; Jung, W. H.; Beemelmanns C.; Kim, K. H. Revised structural assignment of azalomycins based on genomic and chemical analysis. Org. Chem. Front. 2021, 8, 4791.
52. Lee, S. R.; Guo, H.; Yu, J. S.; Park, M.; Dahse, H. M.; Jung, W. H.; Beemelmanns C.; Kim, K. H. Revised structural assignment of azalomycins based on genomic and chemical analysis. Org. Chem. Front. 2021, 8, 4791.
51. Yu, J. S.; Lim, S. H.; Lee, S. R.; Choi, C. I.; Kim, K. H. Antioxidant and anti-inflammatory effects of white mulberry (Morus alba L.) fruits on lipopolysaccharide-stimulated RAW 264.7 macrophages. Molecules 2021, 26, 920.
51. Yu, J. S.; Lim, S. H.; Lee, S. R.; Choi, C. I.; Kim, K. H. Antioxidant and anti-inflammatory effects of white mulberry (Morus alba L.) fruits on lipopolysaccharide-stimulated RAW 264.7 macrophages. Molecules 2021, 26, 920.
50. Schorn, M. A.; Verhoeven, S.; Ridder, L.; Huber, F.;…Lee, S. R.;…van der Hooft, J. J. J. A community resource for paired genomic and metabolomic data mining. Nat. Chem. Biol. 2021, 17, 363-368.
50. Schorn, M. A.; Verhoeven, S.; Ridder, L.; Huber, F.;…Lee, S. R.;…van der Hooft, J. J. J. A community resource for paired genomic and metabolomic data mining. Nat. Chem. Biol. 2021, 17, 363-368.
49. Lee, S. R.; Kang, H.; Yoo, M. J.; Yi, S. A.; Beemelmanns, C.; Kim, K. H. Anti-adipogenic Pregnane Steroid from a Hydractinia-associated Fungus, Cladosporium sphaerospermum SW67. Nat. Prod. Sci. 2020, 26, 230-235.
49. Lee, S. R.; Kang, H.; Yoo, M. J.; Yi, S. A.; Beemelmanns, C.; Kim, K. H. Anti-adipogenic Pregnane Steroid from a Hydractinia-associated Fungus, Cladosporium sphaerospermum SW67. Nat. Prod. Sci. 2020, 26, 230-235.
48. Lee, S. R.; Schalk, F.; Schwitalla, J.; Benndorf, R.; Vollmers, J.; Kaster, A. K.; de Beer, Z. W.; Park, M.; Ahn, M. J.; Jung, W. H. ; Beemelmanns, C.; Kim, K. H. Polyhalogenation of Isoflavonoids by the Termite-Associated Actinomadura sp. RB99. J. Nat. Prod. 2020, 83, 3102-3110.
48. Lee, S. R.; Schalk, F.; Schwitalla, J.; Benndorf, R.; Vollmers, J.; Kaster, A. K.; de Beer, Z. W.; Park, M.; Ahn, M. J.; Jung, W. H. ; Beemelmanns, C.; Kim, K. H. Polyhalogenation of Isoflavonoids by the Termite-Associated Actinomadura sp. RB99. J. Nat. Prod. 2020, 83, 3102-3110.
47. Lee, S. R.; Choi, J. H.; Ryoo, R.; Kim, J. C.; Pang, C.; Kim, S. H.; Kim, K. H. Ergostane-Type Steroids from Korean Wild Mushroom Xerula furfuracea that Control Adipocyte and Osteoblast Differentiation. J. Microbiol. Biotechn. 2020, 30, 1-8.
47. Lee, S. R.; Choi, J. H.; Ryoo, R.; Kim, J. C.; Pang, C.; Kim, S. H.; Kim, K. H. Ergostane-Type Steroids from Korean Wild Mushroom Xerula furfuracea that Control Adipocyte and Osteoblast Differentiation. J. Microbiol. Biotechn. 2020, 30, 1-8.
46. Lee. D.; Lee, S. R.; Kang, K. S.; Kim, K. H. Benzyl salicylate from the stems and stem barks of Cornus walteri as a nephroprotective agent against cisplatin-induced apoptotic cell death in LLC-PK1 cells. RSC Adv. 2020, 10, 5777-5784.
46. Lee. D.; Lee, S. R.; Kang, K. S.; Kim, K. H. Benzyl salicylate from the stems and stem barks of Cornus walteri as a nephroprotective agent against cisplatin-induced apoptotic cell death in LLC-PK1 cells. RSC Adv. 2020, 10, 5777-5784.
45. Lee, S. R.; Lee, D.; Lee, B. S.; Ryoo, R.; Pang, C.; Kang, K. S.; Kim, K. H. Phallac acids A and B, new sesquiterpenes from the fruiting bodies of Phallus luteus J. Antibiot. 2020, 73, 729-732.
45. Lee, S. R.; Lee, D.; Lee, B. S.; Ryoo, R.; Pang, C.; Kang, K. S.; Kim, K. H. Phallac acids A and B, new sesquiterpenes from the fruiting bodies of Phallus luteus J. Antibiot. 2020, 73, 729-732.
44. Lee, S.; Woo, D. C.; Kang, J.; Ra, M.; Kim, K. H.; Lee, S. R.; Choi, D. K.; Lee, H.; Hong, K. B.; Min, S. H.; Lee, Y.; Yu, J. H. The role of the histone methyltransferase EZH2 in liver inflammation and fibrosis in STAM NASH mice. Biology 2020, 9, 93.
44. Lee, S.; Woo, D. C.; Kang, J.; Ra, M.; Kim, K. H.; Lee, S. R.; Choi, D. K.; Lee, H.; Hong, K. B.; Min, S. H.; Lee, Y.; Yu, J. H. The role of the histone methyltransferase EZH2 in liver inflammation and fibrosis in STAM NASH mice. Biology 2020, 9, 93.
43. Lee, S. R.; Kreuzenberg, N.; Jang, M.; Oh, T.; Ko, S. K.; Ahn, J. S.; Beemelmanns, C.; Kim, K. H. Xyloneside A: a new glycosylated incisterol derivative from Xylaria sp. FB. ChemBioChem 2020, 21, 1-7.
43. Lee, S. R.; Kreuzenberg, N.; Jang, M.; Oh, T.; Ko, S. K.; Ahn, J. S.; Beemelmanns, C.; Kim, K. H. Xyloneside A: a new glycosylated incisterol derivative from Xylaria sp. FB. ChemBioChem 2020, 21, 1-7.
42. Lee, S. R.; Lee, D.; Park, M.; Lee, J. C.; Park, H. J.; Kang, K. S.; Kim, C. E.; Beemelmanns, C.; Kim, K. H. Absolute Configuration and Corrected NMR Assignment of 17-Hydroxycyclooctatin, a Fused 5-8-5 Tricyclic Diterpene. J. Nat. Prod. 2020, 83, 354-361.
42. Lee, S. R.; Lee, D.; Park, M.; Lee, J. C.; Park, H. J.; Kang, K. S.; Kim, C. E.; Beemelmanns, C.; Kim, K. H. Absolute Configuration and Corrected NMR Assignment of 17-Hydroxycyclooctatin, a Fused 5-8-5 Tricyclic Diterpene. J. Nat. Prod. 2020, 83, 354-361.
41. Lee, S. R.; Yi, S. A.; Nam, K. H.; Park, J. G.; Hwang, J. S.; Lee, J.; Kim, K. H. (±)-Kituramides A and B, pairs of enantiomeric dopamine dimers from the two-spotted cricket Gryllus bimaculatus. Bioorg. Chem. 2020, 95, 103554.
41. Lee, S. R.; Yi, S. A.; Nam, K. H.; Park, J. G.; Hwang, J. S.; Lee, J.; Kim, K. H. (±)-Kituramides A and B, pairs of enantiomeric dopamine dimers from the two-spotted cricket Gryllus bimaculatus. Bioorg. Chem. 2020, 95, 103554.
40. Kwon, S. H.; Lee, S. R.; Park, Y. J.; Ra, M.; Lee, Y.; Pang, C.; Kim, K. H. Suppression of 6-hydroxydopamine-induced oxidative stress by hyperoside via activation of Nrf2/HO-1 signaling in dopaminergic neurons. Int. J. Mol. Sci. 2019, 20, 5832
40. Kwon, S. H.; Lee, S. R.; Park, Y. J.; Ra, M.; Lee, Y.; Pang, C.; Kim, K. H. Suppression of 6-hydroxydopamine-induced oxidative stress by hyperoside via activation of Nrf2/HO-1 signaling in dopaminergic neurons. Int. J. Mol. Sci. 2019, 20, 5832
39. Lee, S. R.; Yi, S. A.; Nam, K.; Ryoo, R.; Lee, J.; Kim, K. H. Pantheric acids A-C from a poisonous mushroom, Amanita pantherina promote lipid accumulation in adipocytes. J. Nat. Prod. 2019, 82, 3489-3493.
39. Lee, S. R.; Yi, S. A.; Nam, K.; Ryoo, R.; Lee, J.; Kim, K. H. Pantheric acids A-C from a poisonous mushroom, Amanita pantherina promote lipid accumulation in adipocytes. J. Nat. Prod. 2019, 82, 3489-3493.
38. Lee, S. R.; Lee D.; Eom H. J.; Rischer M.; Ko Y. J.; Kang K. S.; Kim C. S.; Beemelmanns C.; Kim K. H. Hybrid Polyketides from a Hydractinia-associated Cladosporium sphaerospermum SW67 and Their Putative Biosynthetic Origin. Mar. Drugs 2019, 17, 606.
38. Lee, S. R.; Lee D.; Eom H. J.; Rischer M.; Ko Y. J.; Kang K. S.; Kim C. S.; Beemelmanns C.; Kim K. H. Hybrid Polyketides from a Hydractinia-associated Cladosporium sphaerospermum SW67 and Their Putative Biosynthetic Origin. Mar. Drugs 2019, 17, 606.
37. Klassen, J. L; Lee, S. R.; Thomas-Poulsen, M.; Beemelmanns, C.; Kim, K. H. Efomycins K and L from a Termite-associated Streptomyces sp. M56 and Their Putative Biosynthetic Origin. Front. Microbiol. 2019, 10, 1739.
37. Klassen, J. L; Lee, S. R.; Thomas-Poulsen, M.; Beemelmanns, C.; Kim, K. H. Efomycins K and L from a Termite-associated Streptomyces sp. M56 and Their Putative Biosynthetic Origin. Front. Microbiol. 2019, 10, 1739.
36. Lee, D.; Lee, S. R.; Kang, K. S.; Ko, Y.; Pang, C.; Yamabe, N.; Kim, K. H. Betulinic acid suppresses ovarian cancer cell proliferation through induction of apoptosis. Biomolecules 2019, 9, 257.
36. Lee, D.; Lee, S. R.; Kang, K. S.; Ko, Y.; Pang, C.; Yamabe, N.; Kim, K. H. Betulinic acid suppresses ovarian cancer cell proliferation through induction of apoptosis. Biomolecules 2019, 9, 257.
35. Yoon, S. Y.; Lee, S. R.; Hwang, J. Y.; Benndorf, R.; Beemelmanns, C.; Chung, S. J.; Kim, K. H. Fridamycin A, a microbial natural product, stimulates glucose uptake without inducing adipogenesis. Nutrients 2019, 11, 765.
35. Yoon, S. Y.; Lee, S. R.; Hwang, J. Y.; Benndorf, R.; Beemelmanns, C.; Chung, S. J.; Kim, K. H. Fridamycin A, a microbial natural product, stimulates glucose uptake without inducing adipogenesis. Nutrients 2019, 11, 765.
34. Lee, T. K.; Lee, D.; Lee, S. R.; Ko, Y. J.; Kang, K. S.; Chung, S. J.; Kim, K. H. Sesquiterpenes from Curcuma zedoaria rhizomes and their cytotoxicity against human gastric cancer AGS cells. Bioorg. Chem. 2019, 87, 117-122.
34. Lee, T. K.; Lee, D.; Lee, S. R.; Ko, Y. J.; Kang, K. S.; Chung, S. J.; Kim, K. H. Sesquiterpenes from Curcuma zedoaria rhizomes and their cytotoxicity against human gastric cancer AGS cells. Bioorg. Chem. 2019, 87, 117-122.
33. Jo, B. G.; Park, N. J.; Kim, S.; Jegal, J.; Choi, S. H.; Lee, S. W. ; Yi, L. W.; Lee, S. R.; Kim, K. H.; Yang, M. H. Isolation of maltol derivatives from Stellera chamaejasme and the anti-atopic properties of maltol on skin lesions in DNCB-stimulated mice. RSC adv. 2019, 9, 2125-2132.
33. Jo, B. G.; Park, N. J.; Kim, S.; Jegal, J.; Choi, S. H.; Lee, S. W. ; Yi, L. W.; Lee, S. R.; Kim, K. H.; Yang, M. H. Isolation of maltol derivatives from Stellera chamaejasme and the anti-atopic properties of maltol on skin lesions in DNCB-stimulated mice. RSC adv. 2019, 9, 2125-2132.
32. Rischera, M.; Lee, S. R.; Eom, H. J.; Park, H. B.; Vollmers, J.; Kaster, A. K.; Shin, Y. H.; Oh, D. C.; Kim, K. H.; Beemelmanns, C. Spirocyclic cladosporicin A and cladosporiumins I and J from a hydractinia-associated Cladosporium sphaerospermum SW67. Org. Chem. Front. 2019, 6, 1084-1093.
32. Rischera, M.; Lee, S. R.; Eom, H. J.; Park, H. B.; Vollmers, J.; Kaster, A. K.; Shin, Y. H.; Oh, D. C.; Kim, K. H.; Beemelmanns, C. Spirocyclic cladosporicin A and cladosporiumins I and J from a hydractinia-associated Cladosporium sphaerospermum SW67. Org. Chem. Front. 2019, 6, 1084-1093.
31. Lee, S. R.; Küfner, M.; Park, M.; Jung, W. H.; Choi, S. U.; Beemelmanns, C.; Kim, K. H.. Beauvetetraones A-C, phomaligadione-derived polyketide dimers from the entomopathogenic fungus, Beauveria bassiana. Org. Chem. Front. 2019, 6, 162-166.
31. Lee, S. R.; Küfner, M.; Park, M.; Jung, W. H.; Choi, S. U.; Beemelmanns, C.; Kim, K. H.. Beauvetetraones A-C, phomaligadione-derived polyketide dimers from the entomopathogenic fungus, Beauveria bassiana. Org. Chem. Front. 2019, 6, 162-166.
30. Lee, S. R.; Seok, S.; Ryoo, R.; Choi, S. U.; Kim, K. H. Macrocyclic Trichothecene Mycotoxins from a Deadly Poisonous Mushroom Podostroma cornu-damae. J. Nat. Prod. 2019, 82, 122-128.
30. Lee, S. R.; Seok, S.; Ryoo, R.; Choi, S. U.; Kim, K. H. Macrocyclic Trichothecene Mycotoxins from a Deadly Poisonous Mushroom Podostroma cornu-damae. J. Nat. Prod. 2019, 82, 122-128.
29. Lee, T. k.; Trinh, T. A.; Lee, S. R.; Kim, S.; So, H. M.; Moon, E.; Hwang, G. S.; Kang, K. S.; Kim, J. H.; Yamabe, N.; Kim, K. H. Bioactivity-based analysis and chemical characterization of anti-inflammatory compounds from Curcuma zedoaria rhizomes using LPS-stimulated RAW264.7 cells. Bioorg. Chem. 2019, 82, 26-32.
29. Lee, T. k.; Trinh, T. A.; Lee, S. R.; Kim, S.; So, H. M.; Moon, E.; Hwang, G. S.; Kang, K. S.; Kim, J. H.; Yamabe, N.; Kim, K. H. Bioactivity-based analysis and chemical characterization of anti-inflammatory compounds from Curcuma zedoaria rhizomes using LPS-stimulated RAW264.7 cells. Bioorg. Chem. 2019, 82, 26-32.
28. Lee, S. R.; Park, Y. J.; Han, Y. B.; Lee, J. C.; Lee, S.; Park, H. J.; Lee, H. J.; Kim, K. H. Isoamericanoic acid B from Acer tegmentosum as a potential phytoestrogen. Nutrients 2018, 10, 1915.
28. Lee, S. R.; Park, Y. J.; Han, Y. B.; Lee, J. C.; Lee, S.; Park, H. J.; Lee, H. J.; Kim, K. H. Isoamericanoic acid B from Acer tegmentosum as a potential phytoestrogen. Nutrients 2018, 10, 1915.
27. Lee, S. R.; Lee, D.; Yu, J. S.; Benndorf, R.; Lee, S.; Lee, D. S.; Huh, J.; Beer, Z. W.; Kim, Y. H.; Beemelmanns, C.; Kang, K. S.; Kim, K. H. Natalenamides A-C, cyclic tripeptides from the termite-associated Actinomadura sp. RB99. Molecules 2018, 23, 3003.
27. Lee, S. R.; Lee, D.; Yu, J. S.; Benndorf, R.; Lee, S.; Lee, D. S.; Huh, J.; Beer, Z. W.; Kim, Y. H.; Beemelmanns, C.; Kang, K. S.; Kim, K. H. Natalenamides A-C, cyclic tripeptides from the termite-associated Actinomadura sp. RB99. Molecules 2018, 23, 3003.
26. Lee, S. R.; Park, H. B.; Kim, K. H. Highly sensitive, simple, and cost- and time-effective method to determine the absolute configuration of a secondary alcohol using competing enantioselective acylation coupled with LC/MS. Anal. Chem. 2018, 90, 13212-13216
26. Lee, S. R.; Park, H. B.; Kim, K. H. Highly sensitive, simple, and cost- and time-effective method to determine the absolute configuration of a secondary alcohol using competing enantioselective acylation coupled with LC/MS. Anal. Chem. 2018, 90, 13212-13216
25. Lee, S. R.; Choi, E.; Jeon, S. H.; Zhi, X. Y.; Yu, J. S.; Kim, S. H.; Lee, J.; Park, K. M.; Kim, K. H. Tirucallane triterpenoids from the stems and stem bark of Cornus walteri that control adipocyte and osteoblast differentiations. Molecules 2018, 23, 2732.
25. Lee, S. R.; Choi, E.; Jeon, S. H.; Zhi, X. Y.; Yu, J. S.; Kim, S. H.; Lee, J.; Park, K. M.; Kim, K. H. Tirucallane triterpenoids from the stems and stem bark of Cornus walteri that control adipocyte and osteoblast differentiations. Molecules 2018, 23, 2732.
24. Park, Y. J.; Lee, S. R.; Kim, D. M.; Yu, J. S.; Beemelmanns, C.; Chung, K. H.; Kim, K. H. The inhibitory effects of cyclodepsipeptides from the entomopathogenic fungus Beauveria bassiana on myofibroblast differentiation in A549 alveolar epithelial cells. Molecules 2018, 23, 2568.
24. Park, Y. J.; Lee, S. R.; Kim, D. M.; Yu, J. S.; Beemelmanns, C.; Chung, K. H.; Kim, K. H. The inhibitory effects of cyclodepsipeptides from the entomopathogenic fungus Beauveria bassiana on myofibroblast differentiation in A549 alveolar epithelial cells. Molecules 2018, 23, 2568.
23. Lee, S. R.; Song, J. H.; Song, J. H.; Ko, H. J.; Baek, J. Y.; Trinh, T. A.; Beemelmanns, C.; Yamabe, N.; Kim, K. H. Chemical Identification of Isoflavonoids from a Termite-Associated Streptomyces sp. RB1 and Their Neuroprotective Effects in Murine Hippocampal HT22 Cell Line. Int. J. Mol. Sci. 2018, 19, 2640.
23. Lee, S. R.; Song, J. H.; Song, J. H.; Ko, H. J.; Baek, J. Y.; Trinh, T. A.; Beemelmanns, C.; Yamabe, N.; Kim, K. H. Chemical Identification of Isoflavonoids from a Termite-Associated Streptomyces sp. RB1 and Their Neuroprotective Effects in Murine Hippocampal HT22 Cell Line. Int. J. Mol. Sci. 2018, 19, 2640.
22. Lee, D.; Yu, J. S.; Lee, S. R.; Hwang, G. S.; Kang, K. S.; Park, J. G.; Kim, H. Y.; Kim, K. H.; Yamabe, N. Beneficial effects of bioactive compounds in mulberry fruits against cisplatin-induced nephrotoxicity. Int. J. Mol. Sci. 2018, 19, 1117.
22. Lee, D.; Yu, J. S.; Lee, S. R.; Hwang, G. S.; Kang, K. S.; Park, J. G.; Kim, H. Y.; Kim, K. H.; Yamabe, N. Beneficial effects of bioactive compounds in mulberry fruits against cisplatin-induced nephrotoxicity. Int. J. Mol. Sci. 2018, 19, 1117.
21. Song, J. H.; Lee, D.; Lee, S. R.; Yu, J. S.; Jang, T. S.; Nam, J. W.; Kim, K. H.; Kang, K. S. Identification of bioactive heterocyclic compounds from mulberry and their protective effect against streptozotocin-induced apoptosis in INS-1 cells. Mol. Med. Rep. 2018, 17, 5982-5987.
21. Song, J. H.; Lee, D.; Lee, S. R.; Yu, J. S.; Jang, T. S.; Nam, J. W.; Kim, K. H.; Kang, K. S. Identification of bioactive heterocyclic compounds from mulberry and their protective effect against streptozotocin-induced apoptosis in INS-1 cells. Mol. Med. Rep. 2018, 17, 5982-5987.
20. Lee, S. R.; Roh, H. S.; Lee, S.; Park, H. B.; Jang, T. S.; Ko, Y. J.; Baek, K. H.; Kim, K. H. Bioactivity-guided isolation and chemical characterization of antiproliferative constituents from morel mushroom (Morchella esculenta) in human lung adenocarcinoma cells. J. Funct. Foods 2018, 40, 249-260.
20. Lee, S. R.; Roh, H. S.; Lee, S.; Park, H. B.; Jang, T. S.; Ko, Y. J.; Baek, K. H.; Kim, K. H. Bioactivity-guided isolation and chemical characterization of antiproliferative constituents from morel mushroom (Morchella esculenta) in human lung adenocarcinoma cells. J. Funct. Foods 2018, 40, 249-260.
19. Yu, J. S.; Lee, D.; Lee, S. R.; Lee, J. W.; Choi, C. I.; Jang, T. S.; Kang, K. S.; Kim, K. H. Chemical characterization of cytotoxic indole acetic acid derivative from mulberry fruit (Morus alba L.) against human cervical cancer. Bioorg. Chem. 2018, 76, 28–36.
19. Yu, J. S.; Lee, D.; Lee, S. R.; Lee, J. W.; Choi, C. I.; Jang, T. S.; Kang, K. S.; Kim, K. H. Chemical characterization of cytotoxic indole acetic acid derivative from mulberry fruit (Morus alba L.) against human cervical cancer. Bioorg. Chem. 2018, 76, 28–36.
18. Lee, Y.; Kwon, D. J.; Kim, Y. H.; Ra, M.; Heo, S. I.; Ahn, W. G.; Park, J. R.; Lee, S. R.; Kim, K. H.; Kim, S. Y. HIMH0021 attenuates ethanol-induced liver injury and steatosis in mice. PLoS ONE 2017, 12, e0185134.
18. Lee, Y.; Kwon, D. J.; Kim, Y. H.; Ra, M.; Heo, S. I.; Ahn, W. G.; Park, J. R.; Lee, S. R.; Kim, K. H.; Kim, S. Y. HIMH0021 attenuates ethanol-induced liver injury and steatosis in mice. PLoS ONE 2017, 12, e0185134.
17. Shin, S. H.; Lee, S. R.; Lee, E.; Kim, K. H.; Byun, S. Caffeic Acid Phenethyl Ester from the Twigs of Cinnamomum cassia Inhibits Malignant Cell Transformation by Inducing c‑Fos Degradation. J. Nat. Prod. 2017, 80, 2124–2130.
17. Shin, S. H.; Lee, S. R.; Lee, E.; Kim, K. H.; Byun, S. Caffeic Acid Phenethyl Ester from the Twigs of Cinnamomum cassia Inhibits Malignant Cell Transformation by Inducing c‑Fos Degradation. J. Nat. Prod. 2017, 80, 2124–2130.
16. Lee, S. R.; Nam, J. W.; Kim, K. H. New Triterpenoids from the Stems of Cornus walteri. Chem. Pharm. Bull. 2017, 65, 683−686.
16. Lee, S. R.; Nam, J. W.; Kim, K. H. New Triterpenoids from the Stems of Cornus walteri. Chem. Pharm. Bull. 2017, 65, 683−686.
15. Lee, S. R.; Moo, E.; Kim, K. H. Neolignan and monoterpene glycoside from the seeds of Pharbitis nil. Phytochem. Lett. 2017, 20, 98-101.
15. Lee, S. R.; Moo, E.; Kim, K. H. Neolignan and monoterpene glycoside from the seeds of Pharbitis nil. Phytochem. Lett. 2017, 20, 98-101.
14. Lee, S. R.; Lee, D.; Lee, H. J.; Noh, H. J.; Jung, K.; Kang, K. S.; Kim, K. H. Renoprotective chemical constituents from an edible mushroom, Pleurotus cornucopiae in cisplatin-induced nephrotoxicity. Bioorg. Chem. 2017, 71, 67–73
14. Lee, S. R.; Lee, D.; Lee, H. J.; Noh, H. J.; Jung, K.; Kang, K. S.; Kim, K. H. Renoprotective chemical constituents from an edible mushroom, Pleurotus cornucopiae in cisplatin-induced nephrotoxicity. Bioorg. Chem. 2017, 71, 67–73
13. Lee, S. R.; Lee, S.; Moon, E.; Park, H. J.; Park, H. B.; Kim, K. H. Bioactivity-guided isolation of anti-inflammatory triterpenoids from the sclerotia of Poria cocos using LPS-stimulated Raw264.7 cells. Bioorg. Chem. 2017, 70, 94-99.
13. Lee, S. R.; Lee, S.; Moon, E.; Park, H. J.; Park, H. B.; Kim, K. H. Bioactivity-guided isolation of anti-inflammatory triterpenoids from the sclerotia of Poria cocos using LPS-stimulated Raw264.7 cells. Bioorg. Chem. 2017, 70, 94-99.
12. Byun, S.; Shin, S. H.; Park, J.; Lim, S.; Lee, E.; Lee, C.; Sung, D.; Farrand, L.; Lee, S. R.; Kim, K. H.; Dong, Z.; Lee S. W.; Lee, K. W. Sulforaphene suppresses growth of colon cancer-derived tumors via induction of glutathione depletion and microtubule depolymerization. Mol. Nutr. Food Res. 2016, 60, 1068–1078.
12. Byun, S.; Shin, S. H.; Park, J.; Lim, S.; Lee, E.; Lee, C.; Sung, D.; Farrand, L.; Lee, S. R.; Kim, K. H.; Dong, Z.; Lee S. W.; Lee, K. W. Sulforaphene suppresses growth of colon cancer-derived tumors via induction of glutathione depletion and microtubule depolymerization. Mol. Nutr. Food Res. 2016, 60, 1068–1078.
11. Lee, S. R.; Park, J. Y.; Yu, J. S.; Lee, S. O.; Ryu, J. Y.; Choi, S. Z.; Kang, K. S.; Yamabe, N.; Kim, K. H. Odisolane, a Novel Oxolane Derivative and Antiangiogenic Constituents from the Fruits of Mulberry (Morus alba L.). J. Agric. Food Chem. 2016, 64, 3804−3809.
11. Lee, S. R.; Park, J. Y.; Yu, J. S.; Lee, S. O.; Ryu, J. Y.; Choi, S. Z.; Kang, K. S.; Yamabe, N.; Kim, K. H. Odisolane, a Novel Oxolane Derivative and Antiangiogenic Constituents from the Fruits of Mulberry (Morus alba L.). J. Agric. Food Chem. 2016, 64, 3804−3809.
10. Lee, S. R.; Beemelmanns, C.; Tsuma, L. M. M.; Clardy, J.; Cao, S.; Kim, K. H. A new diketopiperazine, cyclo(D-trans-Hyp-L-Leu) from a Kenyan bacterium Bacillus licheniformis LB 8CT. Nat. Prod. Commun. 2016, 11, 461-463.
10. Lee, S. R.; Beemelmanns, C.; Tsuma, L. M. M.; Clardy, J.; Cao, S.; Kim, K. H. A new diketopiperazine, cyclo(D-trans-Hyp-L-Leu) from a Kenyan bacterium Bacillus licheniformis LB 8CT. Nat. Prod. Commun. 2016, 11, 461-463.
9. Lee, S. R.; Clardy, J.; Senger, D. R.; Cao, S.; Kim, K. H. Iridoid and phenylethanoid glycosides from the aerial part of Barleria lupulina. Braz. J. Pharmacog. 2016, 26, 281-284.
9. Lee, S. R.; Clardy, J.; Senger, D. R.; Cao, S.; Kim, K. H. Iridoid and phenylethanoid glycosides from the aerial part of Barleria lupulina. Braz. J. Pharmacog. 2016, 26, 281-284.
8. Suh, W. S.; Lee, S. R.; Kim, C. S.; Moon, E.; Kim, S. Y.; Choi, S. U.; Kang, K. S.; Lee, K. R.; Kim, K. H. A new monoacylglycerol from the fruiting bodies of Gymnopilus spectabilis. J. Chem. Res. 2016, 40, 156-159.
8. Suh, W. S.; Lee, S. R.; Kim, C. S.; Moon, E.; Kim, S. Y.; Choi, S. U.; Kang, K. S.; Lee, K. R.; Kim, K. H. A new monoacylglycerol from the fruiting bodies of Gymnopilus spectabilis. J. Chem. Res. 2016, 40, 156-159.
7. Lee, S. R.; Han, J. Y.; Kang, H. R.; Lee, H. L.; Noh, H. J.; Cha, J. S.; Kang, K. S.; Lee, C. J.; Kim, K. H. A New Steroidal Saponin from the Tubers of Ophiopogon japonicus and Its Protective Effect Against Cisplatin-Induced Renal Cell Toxicity J. Braz. Chem. Soc. 2016, 27, 706-711.
7. Lee, S. R.; Han, J. Y.; Kang, H. R.; Lee, H. L.; Noh, H. J.; Cha, J. S.; Kang, K. S.; Lee, C. J.; Kim, K. H. A New Steroidal Saponin from the Tubers of Ophiopogon japonicus and Its Protective Effect Against Cisplatin-Induced Renal Cell Toxicity J. Braz. Chem. Soc. 2016, 27, 706-711.
6. Kang, H. R.; Lee, D.; Eom, H. J.; Lee, S. R.; Lee, K. R.; Kang, K. S.; Kim, K. H. Identification and mechanism of action of renoprotective constituents from peat moss Sphagnum palustre in cisplatin-induced nephrotoxicity. J. Funct. Foods 2016, 20, 358–368.
6. Kang, H. R.; Lee, D.; Eom, H. J.; Lee, S. R.; Lee, K. R.; Kang, K. S.; Kim, K. H. Identification and mechanism of action of renoprotective constituents from peat moss Sphagnum palustre in cisplatin-induced nephrotoxicity. J. Funct. Foods 2016, 20, 358–368.
5. Lee, S. R.; Jung, K.; Noh, H. J.; Park, Y. J.; Lee, H. L.; Lee, K. R.; Kang, K. S.; Kim, K. H. A new cerebroside from the fruiting bodies of Hericium erinaceus and its applicability to cancer treatment. Bioorg. Med. Chem. Lett. 2015, 25, 5712–5715.
5. Lee, S. R.; Jung, K.; Noh, H. J.; Park, Y. J.; Lee, H. L.; Lee, K. R.; Kang, K. S.; Kim, K. H. A new cerebroside from the fruiting bodies of Hericium erinaceus and its applicability to cancer treatment. Bioorg. Med. Chem. Lett. 2015, 25, 5712–5715.
4. Lee, S.; Jung, K.; Lee, D.; Lee, S. R.; Lee, K. R.; Kang, K. S.; Kim, K. H. Protective effect and mechanism of action of lupane triterpenes from Cornus walteri in cisplatin-induced nephrotoxicity. Bioorg. Med. Chem. Lett. 2015, 25, 5613–5618.
4. Lee, S.; Jung, K.; Lee, D.; Lee, S. R.; Lee, K. R.; Kang, K. S.; Kim, K. H. Protective effect and mechanism of action of lupane triterpenes from Cornus walteri in cisplatin-induced nephrotoxicity. Bioorg. Med. Chem. Lett. 2015, 25, 5613–5618.
3. Kim, K. H.; Moon, E.; Lee, S. R.; Park, K. J.; Kim, S. Y.; Choi, S. U.; Lee, K. R. Chemical Constituents of the Seeds of Raphanus sativus and their Biological Activity. J. Braz. Chem. Soc. 2015, 26, 2307-2312.
3. Kim, K. H.; Moon, E.; Lee, S. R.; Park, K. J.; Kim, S. Y.; Choi, S. U.; Lee, K. R. Chemical Constituents of the Seeds of Raphanus sativus and their Biological Activity. J. Braz. Chem. Soc. 2015, 26, 2307-2312.
2. Choi, C. I.; Lee, S. R.; Kim, K. H. Antioxidant and α-glucosidase inhibitory activities of constituents from Euonymus alatus twigs. Ind. Crop. Prod. 2015, 76, 1055–1060.
2. Choi, C. I.; Lee, S. R.; Kim, K. H. Antioxidant and α-glucosidase inhibitory activities of constituents from Euonymus alatus twigs. Ind. Crop. Prod. 2015, 76, 1055–1060.
1. Kang, H. R.; Eom, H. J.; Lee, S. R.; Choi, S. U.; Kang, K. S.; Lee, K. R.; Kim, K. H. Bioassay-guided Isolation of Antiproliferative Triterpenoids from Euonymus alatus Twigs. Nat. Prod. Commun. 2015, 10, 1929–1932.
1. Kang, H. R.; Eom, H. J.; Lee, S. R.; Choi, S. U.; Kang, K. S.; Lee, K. R.; Kim, K. H. Bioassay-guided Isolation of Antiproliferative Triterpenoids from Euonymus alatus Twigs. Nat. Prod. Commun. 2015, 10, 1929–1932.
