Dr. Souradyuti Ghosh (Team Leader)

• Associate Professor, Centre for Life Sciences, Mahindra University (2023 - now)

• Scientist, UGC-DAE CSR Kolkata center (2022-2023)

• Associate Professor, Chemistry and Biotechnology, Bennett University (July 2021 - May 2022)

• Assistant Professor, Chemistry and Biotechnology, Bennett University (Dec 2016 - now)

• Postdoctoral Researcher, Aye Lab, Chemistry and Chemical Biology, Cornell University (2015-2016)

• PhD, Greenberg lab, Johns Hopkins University (2009 - 2015)

• MSc, Chandrakumar lab, IIT Madras (2006-08)

• BSc, Chemistry, 2006 (Ramakrishna Mission Residential College, Narendrapur)

Project working on: DNA nanotriangle probe, centrifuge for resource limited settings

Contact: souradyuti.ghosh@mahindrauniversity.edu.in; souradyutighoshacademic@gmail.com; 

Mr Avinash Vahinde (JRF,  DST CEFIPRA, April 2025- ongoing)

M.Sc. National Forensic Science University, Goa....Forensic Sciences

B.Sc. Amity University....Forensic Sciences

Project working on: Nucleic acid sensors 

Ms. Chandrika Sharma (Ph.D. student, Jan 2024- ongoing)

B.Tech. Bennett University

Project working on (Jan 2024- now): Nucleic acid therapeutics

Outcomes

Publications

• S Kumar, HS Gariya, C Sharma, S Parveen, VK Nair, M Sengupta,  S Ghosh*. An anomalous 3’-terminal phosphorothioated mismatch bypass activity and its application as a binary molecular switch. BioRxiv preprint 2024. doi: https://doi.org/10.1101/2024.07.27.605420

• VK Nair#, C Sharma#, S Kumar, M Sengupta, S Ghosh*. Mitigating the Non-Specific Amplification in RCA: Assessment of the Role of Ligation and Exonuclease Digestion in Circular DNA Preparation. Preprint ChemRxiv https://doi.org/10.26434/chemrxiv.14577975.v1 [Accepted in RSC Analyst IF 3.6]   (# joint 1st author)

Patents: 

• Functional nucleic acid assembly and uses thereof. Shrawan Kumar, Saba Parveen, Chandrika Sharma, S Ghosh, M Sengupta (filing no 202341080341)

• Methods for degradation of acyclic deoxyribonucleotide polymer and preparation of high purity circular single stranded deoxyribonucleotide polymer. Vandana KN, C Sharma, S Ghosh (Filing no: 202111017845)

Ms. Saba Parveen (DST INSPIRE JRF / Ph.D. student, August 2022 - ongoing)

MSc:  Vinoba Bhave University, Hazaribagh-Jharkhand

BSc: Vinoba Bhave University, Hazaribagh-Jharkhand

Project working on (August 2022 - now): Nucleic acid therapeutics

Patents

• Functional nucleic acid assembly and uses thereof. Shrawan Kumar, Saba Parveen, Chandrika Sharma, S Ghosh, M Sengupta (filing no 202341080341)

Mr. Shrawan Kumar (JRF, Jan 2021 - March 2022 and PhD student since  March 2022)

MSc:  Vinoba Bhave University, Hazaribagh-Jharkhand

BSc: Vinoba Bhave University, Hazaribagh-Jharkhand

Project working on (Jan  2021 - now): Dengue detection project

Outcomes

Publications

• S Kumar, A Kharb, A Vazirani, RS Chauhan, G Pramanik, M Sengupta, S Ghosh*, Nucleic acid extraction from complex biofluid using toothpick-actuated over-the-counter medical-grade cotton. ChemRxiv DOI: 10.26434/chemrxiv-2022-v7rmw-v2 [Accepted in Bioorganic and Medicinal Chem, IF 3.6]

• S Kumar, HS Gariya, C Sharma, S Parveen, VK Nair, M Sengupta,  S Ghosh*. An anomalous 3’-terminal phosphorothioated mismatch bypass activity and its application as a binary molecular switch. BioRxiv preprint 2024. doi: https://doi.org/10.1101/2024.07.27.605420

• VK Nair, C Sharma, S Kumar, M Sengupta, S Ghosh*. Mitigating the Non-Specific Amplification in RCA: Assessment of the Role of Ligation and Exonuclease Digestion in Circular DNA Preparation. Preprint ChemRxiv https://doi.org/10.26434/chemrxiv.14577975.v1 [Accepted in RSC Analyst IF 3.6]

• One more manuscript in preparation

Patent

• Methods for identification of charged bioploymers. S Ghosh, A Kumar, M Sengupta, A Talukdar, HS Gariya, S Kumar, VK Nair, S Tripathy, T Agarkar. (provisional application, filing no 202111037358)

• Functional nucleic acid assembly and uses thereof. Shrawan Kumar, Saba Parveen, Chandrika Sharma, S Ghosh, M Sengupta (filing no 202341080341)

Mr. Aditya Chaurasiya (B.Tech. internship student, Jan 2024- ongoing)

B.Tech. Mahindra University (2023-27)

Project working on (Jan 2024- now): Nucleic acid sensor and device development