It is the year Universal Century 0079, and the space colonies have declared war on the Earth Federation under the guidance of the Principality of Zeon. MS IGLOO follows the exploits of the Principality of Zeon's 603rd Technical Evaluation Unit, a special crew of weapons development researchers. Stationed aboard the former civilian cargo ship Jotunheim the unit field-tests various prototype weapons for combat use under the supervision of Engineer Lieutenant Oliver May. IGLOO's six episodes chronicle the 603rd's adventures as pivotal episodes throughout the One-Year War that were barely mentioned in-depth in the original series.

MS-IGLOO 2: Gravity of the Battlefront tells the story of three ill-fated Federation soldiers in their battle against Zeon.