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Octobre 2026

THESIS FUNDING Application deadline in March!

IBMM's F13 team's research, Montpellier

Informations et description du poste : 

Do you have training in molecular modeling/peptide and protein structure ? Are you interested in testing AI methods in a team capable of experimentally verifying your hypotheses based on calculations?

The project is part of the IBMM's F13 team's research theme and aims to better understand the functioning of GPCRs (G protein-coupled receptors) at the molecular level. This thesis will be conducted in a multidisciplinary environment at the interface between modeling, chemistry, and biology. The thesis will aim to demonstrate the value of molecular dynamics for designing binders (peptides/proteins) targeting these receptors using AI, as well as for prioritizing their testing. Our main models will be the ghrelin and motilin receptors. The idea behind the project is to successfully design pharmacological agents that bind specifically to certain conformations of these receptors, but also to their various intracellular partners. Various pipelines based on molecular dynamics (all-atoms/coarse-grained) will be tested, and the most promising molecules will be tested and validated experimentally within our team.

You can apply here:

https://lnkd.in/e4jsUi5m

Please also send your CV/cover letter to nicolas.floquet[a]umontpellier.fr with the subject line “thesis application.”