Our group is deeply interested in understanding "how healthy and diseased lungs respond to various perturbations" at the molecular and cellular levels, and ultimately translating these insights into clinical practice.
To achieve this, we
(1) actively develop disease modeling tools and fine-tune them to address clinically relevant questions,
(2) manipulate these models at the molecular or genomic level, and
(3) evaluate changes using cutting-edge genomic tools.
Lung organoids, PCLS, and
their variants
Drug screening, lineage tracing,
gene editing
scRNAseq, spatial transcriptomics,
ECM architecture analysis
Supported by
과학기술통신부/한국연구재단 - 우수신진연구(글로벌 협력과제)
보건복지부/한국보건산업진흥원 - 의사과학자 박사후 연구성장지원 (심화)
보건복지부/한국보건산업진흥원 - 보건의료기술 연구개발사업: 희귀질환 진단치료 기술개발
Asian Pacific Society of Respirology - Assembly Fund Research
Collaborators