Shin, S.; Kim, Y.-J.; Macatangay, B.J.C.; Cyktor, J.C.; Hines, M.G.; Mellors, J.W.; Dimitrov, D.S.; Li, W.; Baek, D.-S.
Discovery and pre-clinical evaluation of antibodies and bispecific engagers targeting the NKG2A inhibitory receptor.
Science Advances | 2026

Shin, S.; Baek, D.-S.; Mellors, J.W.; Dimitrov, D.S.; Li, W.
Development of Fully Human Antibodies Targeting SIRPα and PLA2G7 for Cancer Therapy.
Antibodies | 2025

Chu, X.; Shin, S.; Baek, D.-S.; Zhang, L.; Conard, A.; Shi, M.; Kim, Y.-J.; Adams, C.; Hines, M.G.; Liu, X.; Chen, C.; Sun, Z.; Jelev, D.V.; Mellors, J.W.; Dimitrov, D.S.; Li, W.
Discovery of a novel highly specific, fully human PSCA antibody and its application as an antibody-drug conjugate in prostate cancer.
mAbs | 2024

Saha, N.; Baek, D.-S.; Mendoza, R.P.; Robev, D.; Xu, Y.; Goldgur, Y.; De La Cruz, M.J.; De Stanchina, E.; Janes, P.W.; Xu, K.; Dimitrov, D.S.; Nikolov, D.B.
Fully human monoclonal antibody targeting activated ADAM10 on colorectal cancer cells.
Biomedicine & Pharmacotherapy | 2023

Kim, Y.-J.; Li, W.; Zhelev, D.V.; Mellors, J.W.; Dimitrov, D.S.; Baek, D.-S.
Chimeric antigen receptor (CAR)-T cells are effective against CEACAM5-expressing non-small cell lung cancer cells resistant to antibody-drug conjugates.
Frontiers in Oncology | 2023

Chu, X.; Baek, D.-S.; Li, W.; Shyp, T.; Mooney, B.; Hines, M.G.; Morin, G.; Sorensen, P.H.; Dimitrov, D.S.
Human antibodies targeting ENPP1 as candidate therapeutics for cancers.
Frontiers in Immunology | 2023

Sullivan, P.M.; Kumar, R.; Li, W.; Hoglund, V.; Wang, L.; Zhang, Y.; Shi, M.; Baek, D.-S.; Cheuk, A.; Jensen, M.C.; Khan, J.; Dimitrov, D.S.; Orentas, R.J.
FGFR4-targeted chimeric antigen receptors (CARs) combined with anti-myeloid poly-pharmacy effectively treats orthotopic rhabdomyosarcoma.
Molecular Cancer Therapeutics | 2022

Baek, D.-S.; Kim, Y.-J.; Vergara, S.; Conard, A.; Adams, C.; Calero, G.; Ishima, R.; Mellors, J.W.; Dimitrov, D.S.
A highly specific fully human antibody and CAR-T cells targeting CD66e effectively kill cancer cells.
Cancer Letters | 2022

Baek, D.-S.; Park, S.-W.; Adams, C.; Dimitrov, D.S.; Kim, Y.-S.
Yeast mating as a tool for highly effective discovery and engineering of antibodies via display methodologies.
Methods in Molecular Biology | 2022

Chu, X.; Sun, Z.; Baek, D.-S.; Li, W.; Mellors, J.W.; Shapiro, S.D.; Dimitrov, D.S.
Human Antibody Domains and Fragments Targeting Neutrophil Elastase as Candidate Therapeutics for Cancer and Inflammation-Related Diseases.
International Journal of Molecular Sciences | 2021

Sun, Z.; Chen, C.; Li, W.; Martinez, D.R.; Drelich, A.; Baek, D.-S.; Liu, X.; Mellors, J.W.; Tseng, C.-T.; Baric, R.S.; Dimitrov, D.S.
Potent neutralization of SARS-CoV-2 by human antibody heavy-chain variable domains isolated from a large library with a new stable scaffold.
mAbs | 2020

Kim, Y.-J.; Baek, D.-S.; Lee, S.; Park, D.; Kang, H.N.; Cho, B.C.; Kim, Y.-S.
Dual-targeting of EGFR and neuropilin-1 overcomes resistance to EGFR-targeted antibody therapy in KRAS-mutant non-small cell lung cancer.
Cancer Letters | 2019

Baek, D.-S.; Kim, J.-H.; Kim, Y.-J.; Kim, Y.-S.
Immunoglobulin Fc-Fused peptide without C-terminal Arg or Lys residue augments neuropilin-1-dependent tumor vascular permeability.
Molecular Pharmaceutics | 2018

Seo, W.-Y.; Kim, J.-H.; Baek, D.-S.; Kim, S.-J.; Kang, S.-J.; Kang, S.-U.; Yang, W.S.; Song, J.-A.; Lee, M.-S.; Kim, S.; Kim, Y.-S.
Production of recombinant human procollagen type I C-terminal propeptide and establishment of a sandwich ELISA for quantification.
Scientific Reports | 2017

Kim, Y.-J.; Jung, K.; Baek, D.-S.; Hong, S.-S.; Kim, Y.-S.
Co-targeting of EGF receptor and neuropilin-1 overcomes cetuximab resistance in pancreatic ductal adenocarcinoma with integrin β1-driven Src-Akt bypass signaling.
Oncogene | 2016

Baek, D.-S.; Kim, Y.-S.
Humanization of a phosphothreonine peptide-specific chicken antibody by combinatorial library optimization of the phosphoepitope-binding motif.
Biochemical and Biophysical Research Communications | 2015

Baek, D.-S.; Kim, Y.-S.
Construction of a large synthetic human Fab antibody library on yeast cell surface by optimized yeast mating.
Journal of Microbiology and Biotechnology | 2014