CV

CURRICULUM VITAE

Revised: [Mar 15, 2024]

 

1.   Name: Shota Nishitani, PhD

 

2.   Office Address:

      Research Center for Child Mental Development, University of Fukui

      23-3 Matsuoka-Shimoaizuki, Eiheiji-cho, Fukui, 910-1193 Japan

 

      Telephone: +81-776-61-8677

 

3.   E-mail Address: nshota[at]u-fukui.ac.jp

 

4.   Citizenship: Japan Citizen

 

5.   Current Titles and Affiliations:

Primary Appointments:

Associate Professor / Lecturer, Research Center for Child Mental Development, University of Fukui, 2022 – present

 

Joint and Secondary Appointments:

Associate Professor / Lecturer, Division of Developmental Higher Brain Functions, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Osaka, Japan 2022 present


6.   Previous Academic and Professional Appointments:

Assistant Professor, Division of Neurobiology and Behavior, Graduate School of Medical Sciences, Nagasaki University, Japan, 2006 – 2017

Visiting Assistant Professor, Psychiatry and Behavioral Sciences, Emory University School of Medicine, 2015 – 2019

Visiting Assistant Professor, Gynecology and Obstetrics, Emory University School of Medicine, 2016 – 2019

Assistant Professor, Research Center for Child Mental Development, University of Fukui, 2019 – 2022

Assistant Professor, Division of Developmental Higher Brain Functions, United Graduate School of Child Development, Osaka University, Kanazawa University, Hamamatsu University School of Medicine, Chiba University, and University of Fukui, Osaka, Japan 2019 – 2022

 

7.   Education:

      BS, Seikei University, Tokyo, Japan, 1997 – 2001

      MS, Yokohama City University, Kanagawa, Japan, 2001 - 2003

      PhD, Nagasaki University, Nagasaki, Japan, 2003 - 2009


8.   Editorial and Peer Review Activities:

 

9.   Honors and Awards:

      Best poster award, 28th Japanese society of Biological Psychiatry, Annual Meeting, 2006

      Young scientist award, 2nd World Federation of Societies of Biological Psychiatry, Asia-Pacific Congress, 2008

      2016 Top Poster Award Finalist, Society of Biological Psychiatry, 2016

      Faculty Award, University of Fukui School of Medical Sciences, 2021

      Outstanding Paper Award, University of Fukui School of Medical Sciences, 2021


10.   Society Memberships:

      The Japan Neuroscience Society, 2005 – present

      Japanese Organization of Clinical Developmental Psychologists, 2013 present


11.   Community Outreach:

 

a.     General:

Science Educational Program for middle and high school students (JSPS), 2010 - 2013

 

12.   Formal Teaching:

a.     Medical Student Teaching:

1)    Neurobiology and Behavior (Shared lecture), for second-year medical students, Nagasaki University, Japan, 2006 – 2014

2)    Human Biology (Shared lecture), for first-year medical students, Nagasaki University, Japan, 2006 – 2014

3)    Neurobiology and Behavior Seminar (Shared lecture), for third-year medical students, Nagasaki University, Japan, 2006 – 2014

4)    Research training, for third-year medical students, Nagasaki University, Japan, 2006 - 2014

 

b.     Graduate Programs:

1)    Neurobiology and Behavior (Shared lecture), for PhD students, Nagasaki University, Japan, 2006 – 2014

2)    Psychosocial Support for Nurturing, for PhD students, University of Fukui, Japan, 2019 - present


c.     Other Categories:

1)    Substitute Instructor, Georgia Japanese Language School, U.S.A, 2018

2)    Physiology, for first-year Nurse students, University of Nagasaki, Japan, 2003 2007

3)    Physiology, for first-year Physical Therapist and Occupational Therapist students, Nagasaki Medical College, Japan, 2006 2008

4)    Physiology, for first-year Nurse students, Nagasaki City Medical Nursing School, Japan, 2008 2014

5)    Sex differences in the brain (Shared lecture), for first-year students, Nagasaki University, Japan, 2012 – 2014

6)    Biology of human communications (Shared lecture), for first-year students, Nagasaki University, Japan, 2012 – 2014

 

13.   Invitations to National/International, Regional, and Institutional Conferences:

1)    Nishitani S, Epigenetic modulation of oxytocin receptor gene in humans, The 33rd Meeting of the Japanese Society for Behavioral Neuroendocrinology, 2021.

2)    Nishitani S, Shinohara K, Chemical communication in humans, The 4th Asia-Pacific Conference on Chemical Ecology (APACE), Ibaraki, Japan, 2007.

 

14.   Abstract Presentations at International, Regional, and Institutional Conferences

1)    Nishitani S and Tomoda A, Epigenetic modifications regulating prosociality and its influence of child maltreatment, 16th International Neuroscience and Biological Psychiatry Conference – ISBS Regional Meeting (Asia), Yamaguchi, Japan, 2022 (oral presentation).

2)    Nishitani S, Kilaru V, Michopoulos V, Winters S, Rothbaum BO, Ressler KJ, Jovanovic T, Smith AK, Prospective longitudinal epigenome-wide association study of the development of PTSD in traumatized ED patients, American College of Neuropsychopharmacology (ACNP) 57th annual meeting, Chicago, IL, 2019 (oral presentation).

3)    Nishitani S, Fujisawa TX, Takiguchi S, Shimada K, Smith AK, Tomoda A, Oxytocin receptor DNA methylation and gray matter volume in maltreated children, American College of Neuropsychopharmacology (ACNP) 56th annual meeting, Palm Springs, CA, 2017 (poster presentation).

4)    Nishitani S, Smith AK, Filkowski MM, Cochran RN, Denison L, Ishak A, Haas BW, Epigenetic modification of OXT and human sociability, Autism Research Symposium, Atlanta, GA, 2016 (poster presentation).

5)    Nishitani S, Michopoulos V, Jovanovic T, Gould F, Nemeroff CB, Meyers AJ, Rothbaum BO, Ressler KJ, Smith AK, Epigenome-wide association study to focus on the development of PTSD in traumatized ED patients, Society of Biological Psychiatry (SOBP) 71st annual meeting, Atlanta, GA, 2016 (poster presentation).

6)    Nishitani S, Kuwamoto S, Takahira A, Shinohara K, The prefrontal cortex was activated in mothers during the odor detection task of the newborn infant, XXXVI International Congress of Physiological Sciences (IUPS), Kyoto, Japan, 2009 (poster presentation).

7)    Nishitani S, Omori A, Kisanuki Y, Koyama A, Doi H, Ikeda E, Onaka T, Shinohara K, A possible role of the right prefronatal cortex in human maternal behavior, 2nd World Federation of Societies of Biological Psychiatry (WFSBP) Asia-Pacific Congress, Toyama, Japan, 2008 (poster presentation).

8)    Nishitani S, Takase R, Miyamura T, Tagawa M, Sumi M, Moriuchi H, Shinohara K, Mother's milk odors attenuated stress responses to heelsticks in human infants, International Conference on Infant Studies (ICIS), Kyoto, Japan, 2006 (poster presentation).

9)    Nishitani S, Moriya T, Kondo Y, Sakuma Y, Shinohara K, Female odor-induced expresion of c-Fos protein expression in oxytocinergic neurons in the paraventricular nucleus in male rats: effects of sexual experience, 14th International Symposium on Olfaction and Taste (ISOT), Kyoto, Japan, 2004 (poster presentation).

 

15.   Research Focus:

  My research aims to identify biological factors that characterize the neurobiological basis of emotional bonding and that promote the formation of a secure attachment relationship between mothers and their children. Early childhood is a period of extensive growth and development, and maltreatment and trauma exposures during this time can increase the risk and severity for varieties of psychiatric disorders in later life. These investigations involve brain imaging, hormone measurements, and molecular (epi)genetics. As a result, I have co-authored several manuscripts on the neurobiological basis related to parental behaviors, child maltreatment, and social behaviors. I had served as the P.I. or Co-investigator of several Japanese governmental grants. Many of these grants rely on “team science” and effective collaboration among an interdisciplinary team of clinicians and basic researchers.

 

16.   Grant Support:

a.     Principal investigator

1)    Life Science Innovation Center Research Funding, University of Fukui, Whole genome analysis of forensic brain and blood DNA methylation in maltreated children (LSI22202), 2022.

2)    JST, Moonshot Goal (9), Realization of a mentally healthy and dynamic society by increasing peace of mind and vitality by 2050, Breaking the intergenerational chain of child maltreatment through primordial prevention (JPMJMS229A), Validation and feasibility of epigenomic panel of child maltreatment status, 2022.

3)   Overseas joint research support within six universities, United Graduate School of Child Development, Osaka University, Development of a Japanese database for the construction of the brain-peripheral tissue methylation correlation database (AMAZE-CpG), 2021.

4)    Life Science Innovation Center Research Funding, University of Fukui, Translational research for determining epigenomic markers of child maltreatment (LSI20305), 2020.

5)    Research promotional aid (support for the start of joint research), University of Fukui, Establishment of novel therapies by intervention on the brain-gut-microbiota (BGM) axis in child maltreatment and elucidation of epigenomic mechanisms of therapeutic effects, 2020.

6)    Grant Aid for the Next Generation of Outstanding Researchers, University of Fukui, Determination of epigenomic markers for the development of novel medicines for child maltreatment, 2020.

7)    Overseas joint research support within six universities, United Graduate School of Child Development, Osaka University, Development of a Japanese database for the construction of the brain-peripheral tissue methylation correlation database (AMAZE-CpG), 2020.

8)    Grant-in-Aid for Scientific Research (C) (20K02700), Japan Society for the Promotion of Science (JSPS) KAKENHI, Imaging epigenome-wide association study to identify biomarkers for child maltreatment, 2020 – 2022.

9)    Overseas joint research support within six universities, United Graduate School of Child Development, Osaka University, Development of a Japanese database for the construction of the brain-peripheral tissue methylation correlation database (AMAZE-CpG), 2019.

10)  Discretionary funds from the Dean of the Faculty for the promotion of Lifecycle Medicine, University of Fukui, School of Medical Sciences, Identification of epigenomic markers for development of epigenetic therapy for child maltreatment, 2019.

11)  Grant Aid for the Next Generation of Outstanding Researchers, University of Fukui, Determination of epigenomic markers for the development of novel medicines for child maltreatment, 2019.

12)  Grant-in-Aid for Scientific Research on Innovative Areas (26118713), Japan Society for the Promotion of Science (JSPS) KAKENHI, A cohort study to elucidate the epigenetic risk factors associated with lower self-regulation during pubertal development, 2014 – 2015.

13) Grant-in-Aid for Challenging Exploratory Research (26670113), Japan Society for the Promotion of Science (JSPS) KAKENHI, Verification of the influences of environmental factors during fetal period on the sex differentiation of the brain and the autistic trait, 2014 – 2016.

14) The President's Discretionary Fund of Nagasaki University, Genome wide methylation analysis associated with maternal brain functions, 2013.

15) Grant-in-Aid for Scientific Research on Innovative Areas (24118505), Japan Society for the Promotion of Science (JSPS) KAKENHI, Elucidation of the genetic and epigenetic risk factors associated with lower self-regulation during pubertal development, 2012 – 2013.

16) Grant-in-Aid for Grant-in-Aid for Young Scientists (B) (24790235), Japan Society for the Promotion of Science (JSPS) KAKENHI, An interpretation study of the mechanisms to acquire the neural basis of maternal behaviors in humans and its endocrine and genetic regulations, 2012 – 2013.

17) The President's Discretionary Fund of Nagasaki University, Influence of vulnerability of oxytocinergic neural functions on the neural basis of maternal behaviors in humans, 2011.

18) General Foundation Hojin-kai medical education grants, 2011.

19) Nagasaki medical Alumni Association medical research grants, Investigation of neural basis of paternal behaviors in humans, 2009.

20) Grant-in-Aid for Grant-in-Aid for Young Scientists (B) (21791136), Japan Society for the Promotion of Science (JSPS) KAKENHI, The pubertal development of the neural basis of attachment in humans, 2009 – 2011.

21) Grant-in-Aid for Grant-in-Aid for Young Scientists (B) (19790180), Japan Society for the Promotion of Science (JSPS) KAKENHI, Determination of the hormonal influences on neural functions associated with emotional responses to infant cues, 2007 – 2008.

 

b.     Co-investigator

1)    Grant-in-Aid for Scientific Research (C) (20K10834), Japan Society for the Promotion of Science (JSPS) KAKENHI, Changes in oxytocin before and after breastfeeding in post-Cesarean section in mothers and possible factors influencing these changes, 2020 – 2023.

2)    AMED, BIRTHDAY (JP20gk0110052), Research for prevention and intervention of child abuse by analyzing vulnerabilities on the brain and epigenome of abused children, 2020-2022.

3)    Grant-in-Aid for Scientific Research (A) (26241016), Japan Society for the Promotion of Science (JSPS) KAKENHI, Genome wide association study to elucidate the developmental neurotoxicity mechanisms via aryl hydrocarbon receptor, 2014 – 2016.

4)    Grant-in-Aid for Scientific Research (C) (25463477), Japan Society for the Promotion of Science (JSPS) KAKENHI, Investigation of oxytocin secretion across the pregnancy and its effect on promotion of maternal attachment formation, 2013 – 2015.

5)    Feasibility study, EXTEND2010, Ministry of the Environment, Assessment of the influence of endocrine disruptors on social behaviors and related brain functions, 2011- 2013.

6)    Grant-in-Aid for Scientific Research (C) (22592486), Japan Society for the Promotion of Science (JSPS) KAKENHI, Investigation of neural basis of maternal behavior during pregnancy, 2010 – 2012.

7)    Grant-in-Aid for Scientific Research (C) (21590259), Japan Society for the Promotion of Science (JSPS) KAKENHI, Investigation of the neuroendocrinological basis involved in the human paternal and maternal behaviors, 2009 – 2011.

8)    Brain Science and Education Program (I), Research Institute of Science and Technology for Society (RISTEX), Japan Science and Technology Agency (JST), Development of non-invasive measurements of non-verbal communications between mother and child, 2004 – 2007.


17.   Bibliography:

a.     Published and Accepted Research Articles (clinical, basic science, other) in Refereed Journals:

 

b.     Published and Accepted Review Articles:

 

c.     Published Book or Book Chapters:

 

d.     Patents:

 

e.     Published Datasets:


 

Current list of publications in Google Scholar:

http://scholar.google.co.jp/citations?user=GiaWnTcAAAAJ&hl=en

 

18.   Contributions Not Otherwise Noted:

         Qualifications

1)    Clinical Developmental Psychologist (Japanese Organization of Clinical Developmental Psychologists)

2)    1st-Class High School Teacher (Japanese Public qualification)

3)    Pollution Control Manager (Water, Class-1) (Japanese National qualification)

4)    Hazardous Materials Handler (Class A and B) (Japanese National qualification)