Professor

논문

• Filamentation in Escherichia coli induced by recombinant alcohol dehydrogenase accumulation, Microbiology and Biotechnology Letters, 202505

• Plant heat shock proteins are more effective in enhancing recombinant alcoho dehydrogenase activity than bacterial ones In vitro, Iranian Journal of Biotechnology, 202406

• Improved recombinant protein production using heat shock proteins in Escherichia coli, Biocatalysis and Agricultural Biotechnology, 202307

• Growth-enhancing effect of bacterial and plant heat shock proteins in Escherichia coli, Biocatalysis and Agricultural Biotechnology, 202211

• Enhanced Acetate Tolerance and Recombinant Protein Accumulation in Escherichia coli by Transgenic Expression of a Heat Shock Protein from Carrot (Daucus carota L.), Iranian Journal of Biotechnology, 202207

• Heterologous expression of heat shock proteins confers stress tolerance in Escherichia coli, an industrial cell factory: A short review, Biocatalysis and Agricultural Biotechnology, 202010

• Enhanced Production of Recombinant Alcohol Dehydrogenase Using the Genetically Engineered Escherichia coli Strain that Heterologously Expresses Carrot Heat Shock Protein 70, Current Microbiology, 201911

• Crystal Structure of Enoyl-Acyl Carrier Protein Reductase (FabI) from Acinetobacter baumannii as a Target for Broad-Spectrum Antibacterial Drug, Bulletin Of The Korean Chemical Society, 201909

• Enhanced recombinant insulin production in transgenic Escherichia coli that heterologously expresses carrot heat shock protein 70, Biocatalysis and Agricultural Biotechnology, 201907

• Cloning, expression, purification, and crystallization of Xoo0878, β-ketoacyl-acyl carrier protein synthase III (FabH), from Xanthomonas oryzae pv. Oryzae, Biodesign, 201906

• Heterologously expressed carrot Hsp17.7 was denatured by ATP treatment under abiotic stress, Biocatalysis and Agricultural Biotechnology, 201806

• N- and C-terminal regions of carrot Heat shock protein 17.7 can confer abiotic stress tolerance to transformed Escherichia coli, Biocatalysis and Agricultural Biotechnology, 201804

• Heterologous Expression of the Carrot Hsp17.7 gene Increased Growth, Cell Viability, and Protein Solubility in Transformed Yeast (Saccharomyces cerevisiae) under Heat, Cold, Acid, and Osmotic Stress Conditions, CURRENT MICROBIOLOGY, 201708

• Multi-walled carbon nanotubes and silver nanoparticles differentially affect seed germination, chlorophyll content, and hydrogen peroxide accumulation in carrot (Daucus carota L.), Biocatalysis and Agricultural Biotechnology, 201610

• Development of Transgenic Escherichia coli with Improved Viability by Heterologous Expression of a Heat Shock Protein Gene from Carrot (Daucus carota L.), HORTSCIENCE, 201603

• Carrot (Daucus carota L.) heat shock protein 70 gene (DcHsp70) confers tolerance to heat or cold stress in E-coli cells, JOURNAL OF HORTICULTURAL SCIENCE BIOTECHNOLOGY, 201507

지식재산

• 당근 Hsp17.7 유전자를 포함하는 에스케리키아 속 미생물을 이용하여 산물을 생산하는 방법, 상명대학교산학협력단, 20190222

• 당근 Hsp17.7 유전자를 포함하는 사카로미세스 속 미생물을 이용하여 산물을 생산하는 방법, 상명대학교산학협력단, 20170904

• 당근 Hsp17.7 유전자를 포함하는 사카로미세스 속 미생물을 이용하여 산물을 생산하는 방법, 상명대학교산학협력단, 20170904

• 나노물질을 이용한 당근의 씨앗 발아율, 엽록소 양 및 과산화수소 축적을 조절하는 방법, 상명대학교산학협력단, 20160909

• 나노 물질 유도된 독성 내성을 부여하는 조성물 및 그 방법(A composition which confer tolerance to nanomaterial-induced toxicity and a method thereof), 상명대학교서울산학협력단, 20140307

• 당근 ＤｃＨｓｐ17.7를 포함하는 중금속 내성 형질전환체, 조성물 및 그 방법(Transformant, Composition and method for increasing cell viability under heavy metal stress comprising Carrot DcHsp17.7), 상명대학교서울산학협력단, 20130227

학술발표

• Heat Shock Protein Co-expression with Recombinant Alcohol Dehydrogenase Resulted in Filamentation in Escherichia coli, International Conference of the Genetics Society of Korea, 20251113

• Improved Solubility and Yield of Recombinant Human Insulin Produced in Escherichia coli via Co-expression of Carrot Heat Shock Protein 70, International Conference of the Genetics Society of Korea, 20251113

• Development of transformed Escherichia coli for recombinant protein production, (사)국제차세대융합기술학회, 20231027

• Heat shock protein을 이용한 재조합 alcohol dehydrogenase의 활성 향상, (사)국제차세대융합기술학회, 20231027

• Crystal structures of peptide deformylase from rice pathogen Xanthomonas oryzae pv. oryzae in complex with substrate peptides, actinonin and fragment chemical compounds, The International Rice Congress, 20231018

• Heterologous Expression of Carrot Heat Shock Protein 70 Improved Yield and Activity of Recombinant Alcohol Dehydrogenase in Escherichia coli, International Society of Biocatalysis and Biotechnology, 20221109

• Heterologous Expression of Carrot Heat Shock Protein 17.7 Enhanced Acetate Tolerance in Escherichia coli , International Society of Biocatalysis and Biotechnology, 20221109

• A Eukaryotic Heat Shock Protein Can Enhance Acetate Tolerance in Transgenic Escherichia coli, The Korean Society for Molecular and Cellular Biology, 20211103

• Enhancement of Abiotic Stress Tolerance in Escherichia coli by Heterologous Expression of Heat Shock Proteins , The Korean Society for Molecular and Cellular Biology, 20211103

• Development of Transgenic Escherichia coli for Improved Recombinant Protein Production, The Genetics Society of Korea 2021, 20211020

• Eukaryotic Heat Shock Protein Can Enhance Recombinant Protein Accumulation in Escherichia coli , The Genetics Society of Korea 2021, 20211020

• Improved recombinant alcohol dehydrogenase production in transgenic Escherichia coli expressing heterologous heat shock protein, 한국통합생물학회, 20201202

• Insulin production in transformed E. coli expressin plant heat shock protein, 한국통합생물학회, 20201202

• Production of recombinant human insulin from transformed Escherichia coli, Korean Society for Biochemistry and Molecular Biology, 20200921

• Production of recombinant alcohol dehydrogenase from transformed Escherichia coli, Korean Society for Biochemistry and Molecular Biology, 20200921

• Improved Recombinant Human Insulin Production by Genetically Engineered Escherichia coli, Korean Society for Molecular and Cellular Biology, 20191001

• Genome Engineering of Escherichia coli for Improved Recombinant Protein Production, Korean Society for Molecular and Cellular Biology, 20191001

• Cell line development for improved recombinant protein production in Escherichia coli, International Society for Biocatalysis and Agricultural Biotechnology, 20190920

• Improved recombinant alcohol dehydrogenase production in genetically engineered Escherichia coli cell line, International Society for Agricultural Biotechnology, 20190920

• Recombinant human insulin production in genetically engineered Escherichia coli, International Society for Biocatalysis and Agricultural Biotechnology, 20190920

• Genetic engineering of industrial microorganisms, International Society of the Biocatalisis and Agricultural Biotechnology, 20181023

• N- and C-terminal Regions of A Carrot Heat shock protein Hsp17.7 Can Function as Molecular Chaperones in the presence of nanomaterials, Korean Society for Molecular and Cellular Biology, 20180918

• Development of Industrial Escherichia coli Cell Lines using Genome Engineering, The International Union of Biochemistry and Molecular Biology, 20180606

• N- and C-terminal Regions of A Carrot Heat shock protein Hsp17.7 Can Function as Molecular Chaperones Under Abiotic Stress, The International Union of Biochemistry and Molecular Biology, 20180606

• Development of Escherichia coli Cell Line Heterologously-Expressing a Carrot Heat Shock Protein 17.7, Korean Society for Molecular and Cellular Biology, 20170914

• A carrot Heat shock protein 70 increases soluble protein levels and cell viability in transformed Escherichia coli, Korean Society for Molecular and Cellular Biology, 20170914

• Homologous recombination of a heat shock protein gene from carrot (Daucus carota L.) enhanced growth of transformed industrial microorganisms, American Society of Plant Biologists, 20160711

프로젝트

• Enhanced recombinant protein production using genome editing (2024~25)

• Improved recombinant protein production using heat shock proteins in Escherichia coli (2023~24)

• 분자 샤페론을 이용한 재조합 단백질의 생산 효율 향상, 한국연구재단, (2015.~2018.)

• 식물 스트레스 저항성 유전자를 이용한 산업용 균주 및 단백질 발현용 연구시약재료 개발, 중소벤처기업부, (2013.~2014.)