International Journal
International Journal
§Co-first author
*Co-correspondence
Group
Ongoing
Graphical abstract
Natural product
Neuron
Pharmacopuncture ameliorates Parkinson’s disease-associated pain via CB1 and PPARγ pathways in an MPTP-induced mouse model
Jung Im Kim, Heerim Yeo, Yousang Jo, Hyungjun Kim, Sang-Min Park*, and No Soo Kim*
Submitted
Natural product
Pinus koraiensis Leaf Extract and Lambertianic Acid Ameliorate Chronic Fatigue through PI3K-Mediated Regulation of Oxidative Stress Response and Mitochondrial Biogenesis
Bo-Ram Lee, Seokwon Kim, Sang-Min Park, Seung-Hyung Kim, Ji Soo Yoon, Sang-Yoon Kim, Sunhoo Kim, and Mi Young Lee
Submitted
Micro
biome
Muscle
Novel Lactobacillus gasseri metabolite alleviate glucocorticoid-induced skeletal muscle atrophy via inhibiting ROS-driven inflammatory cell death and cytokine release
Seongpyo Lee, Sin Young Park, Jayasinghage Nirmani Chathurangika Jayasinghe, Minh Nhat Tran, JuHo Kim, Sang-Min Park*, In Hyun Hwang*, Joo-Hui Han*
Submitted
Natural product
Immnue
Integrative Transcriptomic, Network Pharmacology, and Molecular Docking Approaches Identify Inhibitors of Airway Mucin via NF-κB Signaling
Rajib Hossain, Musun Park, Seongwon Cha, Seokwon Kim, Heerim Yeo, Hyun Jae Lee, Sang-Min Park*, and Choong Jae Lee*
Submitted
AI
A novel preprocessing based on SMILES length originated from concept of active site for efficient deep learning-based bioactivity prediction
JH Kim, SM Park*, JS Kang*
Submitted
PBPK
Reliable Prediction of Hepatic Clearance through Integrated IVIVE, PBPK Modeling, and Regression Analysis
Lahiru Yasas Rathnayaka, Hwi-yeol Yun*,Woojin Jung*, Sang-Min Park*
In preparation
Group
2026
Graphical abstract
AI
Model-Driven Hybrid AI Framework for End-to-End Autonomous Decision-Making in Drug Development
Hyunjung Lee, Hyeonseok Kang, Woojin Jung, Hyojin Cho, Sungwoo Goo, Hwi-yeol Yun, Min-Gul Kim, Jung-woo Chae*, Sang-Min Park*, Soyoung Lee*, Jae Hyun Kim*, Sangkeun Jung*
bioRxiv
Natural product
Su-Jin Baek§, Haeseung Lee§, Sang-Min Park§, Aeyung Kim, No Soo Kim, Eun-Hye Seo, A Yeong Lee, Yu Ri Kim, Wook Jin Kim, Kyu-Won Seo, Musun Park, Jin-Mu Yi, Seongwon Cha
Scientific Data
Marker
Jun-Yeop Song, Hyun Cheol Bang, Young Hyun Son, Dae-In Ha, Eun-Ju Hong, Sun-Woo Lee, Jeongsook Kim, Doyeong Kim, Sang-Min Park, Kyu Pil Lee, Hyo-Jung Kwon, Jeong Hyun Kwon
Advanced Functional Materials, e31941.
Natural product
Eun-Hye Seo, Musun Park, Su-Jin Baek, Haeseung Lee, Sang-Min Park, Aeyung Kim, No Soo Kim, A Yeong Lee, Yu Ri Kim, Jin-Mu Yi, Seongwon Cha
BMC Genomic Data, Accepted
Group
2025
Graphical abstract
Natural product
Cancer
Harnessing transcriptomics for discovery of natural products to overcome acquired cancer resistance
Heerim Yeo§, Sang-Yun Kim§, Sang-Min Park*
Archive of Pharmacal Research, Online published
Natural product
Muscle
Seokwon Kim§, Aeyung Kim§, Minh Nhat Tran, Sang-Yun Kim, Byeong-Don Min, No Soo Kim, Sang-Min Park*
Life Sciences, 124011
Muscle
Chae Young Hwang§, Sang-Min Park§, Hoyeon Lee, Seung-Min Lee, Jeong Yi Choi, Su-Jin Baek, Taeyoung Kim, Yong Ryoul Yang, and Ki-Sun Kwon
The Korean Journal of Physiology & Pharmacology, Accepted
Industry-academia collaborative research
Natural product
Muscle
Aeyung Kim§, Yu Ri Kim§, Jayasinghage Nirmani Chathurangika Jayasinghe§, Musun Park, Seongwon Cha, Sang-Min Park*, and No Soo Kim*
Free Radical Biology and Medicine, 241 (16), 204-219
Natural product
Han Na Kang, Seokwon Kim, Sun Joo Lee, Ami Lee, Seo-Young Lee, Younghoon Go, Jun Hwan Yoo, Sang-Min Park, Yoon Jeong Choi, Youn-Hwan Hwang
Life sciences, 380(1), 123951
Natural product
Muscle
Aeyung Kim§*, Minh Nhat Tran§, A Yeong Lee, Heerim Yeo, Su-Jin Baek, No Soo Kim, Seongwon Cha, Sang-Min Park*
Antioxidants, 14 (7), 795
Spatial
Muscle
Advancing muscle aging and sarcopenia research through spatial transcriptomics
Byeong-Don Min§, Chae Young Hwang§, Doyeong Kim§, Sang-Yun Kim, Jayasinghage Nirmani Chathurangika Jayasinghea, Minh Nhat Tran, Sang-Min Park*, Ki-Sun Kwon*
Osteoporosis and Sarcopenia, 11 (2), 22-31
Industry-academia collaborative research
Natural product
Immune
Sang-Yun Kim§, Jin-Mu Yi§, Jaemoo Chun, Musun Park, Heerim Yeo, Sang-Min Park*, Mi-Kyung Jeong*
Biomedicine & Pharmacotherapy, 188 (2025): 118129.
Marker
Eun Bok Baek, Hyuk Soo Eun, Jun-Yeop Song, Eun-Ju Hong, Se-Hee Park, Poornima Kumbukgahadeniya, Sang-Min Park, Seok-Hwan Kim, Soon Ok Kim, Ha Neul Kim, Young-Eun Cho, Young-Suk Won, Hyo-Jung Kwon
Nature Communications, 16(1), 1-17.
Marker
Transcriptome signatures of human neural stem cells derived from LRRK2 gene therapeutic cells
Doyeong Kim§, Sang-Min Park§, Seo-Young Lee, Sun-Ku Chung
Scientific Reports 15 (1), 12286
Natural product
Cancer
Mibae Jeong, Jaemoo Chun, Sang-Min Park, Heerim Yeo, Se Won Na, In Jin Ha, Bonglee Kim, Mi-Kyung Jeong
Plants 14 (2), 263
Group
2024
Graphical abstract
Natural product
Cancer
Heerim Yeo, Haeseung Lee, Sang-Min Park*, Han Na Kang* (*Co-correspondence)
Life sciences, 357, 123097
Marker
Antisense-mediated splicing correction as a therapeutic approach for p53 K120R mutation
Doyeong Kim§, Sang-Min Park§, SY Lee, J Kim, HB Jung, YS Kim, SK Jeong (*Co-first author)
BMB reports, 57 (11), 503
Natural product
Cancer
SM Park§, H Heo§, HJ Lim, Doyeong Kim, S Cha, M Kim, H Lee
Molecular Oncology, 19.4 (2025): 1155-1169.
Natural product
Immune
Bojungikki-Tang Augments Pembrolizumab Efficacy in Human PBMC-Injected H460 Tumor-Bearing Mice
Se Won Na, Jin-Mu Yi, Heerim Yeo, Sang-Min Park, Mibae Jeong, Jaemoo Chun *, Mi-Kyung Jeong *
Life, 14 (10), 1246
Natural product
Muscle
Aeyung Kim§, Sang-Min Park§, No Soo Kim, Musun Park, Seongwon Cha
Journal of Ginseng Research, 49 (1), 42-52
Natural product
Musun Park§, Sang-Min Park§, Haeseung Lee§, Aeyung Kim, No Soo Kim, Yu Ri Kim, Jin-Mu Yi, Seongwon Cha
Scientific Data, 11 (1), 974
Bioinfo
Unraveling flavivirus pathogenesis: from bulk to single-cell RNA-sequencing strategies
Doyeong Kim, Seonghun Jeong, Sang-Min Park
The Korean Journal of Physiology & Pharmacology, 28(5), 403-411
Natural product
Muscle
A Kim§, YR Kim§, SM Park§, H Lee, M Park, JM Yi, S Cha, NS Kim
Phytomedicine, 123, 155057
Listed in the "한빛사" of BRIC.
Reported in the media "KBS", "YNA".
Group
2023
Graphical abstract
Natural product
M Park, SJ Baek, SM Park, JM Lee, S Cha
Briefings in Bioinformatics, 24(6), bbad344.
Marker
Blood transcriptomic markers associated with immune abnormalities and sleep quality
SM Park§, HJ Ban§, M Lee, SY Kim, S Lee, HJ Jin (*Co-first author)
Genes & Diseases, 101105
Natural product
Muscle
A Kim§, SM Park§, N Kim, HS Lee (*Co-first author)
Antioxidants, 12.8 (2023): 1576
Marker
SM Park§, SH Lee§, O Kwon, S Jeong, S Son, EK Ahn, JY Jang, MK Lee, JH Jang (*Co-first author)
Frontiers in Neuroscience, 17, 1108371
Method
Global stabilizing control of large-scale biomolecular regulatory networks
S An§, SY Jang§, SM Park§, CK Lee, HM Kim, KH Cho (*Co-first author)
Bioinformatics 39 (1), btad045
Natural product
Cancer
J Chun§, SM Park§, M Lee, IJ Ha, MK Jeong (*Co-first author)
Cancers, 15 (3), 653
2022
Systematic transcriptome analysis reveals molecular mechanisms and indications of Bupleuri Radix
SM Park§, A Kim§, H Lee§, SJ Baek, M Park, N Kim, J Lee, S Cha
Frontiers in Pharmacology, 13
M Choi§, SM Park§KH Cho
Communications biology, 5 (1), 1-13
Investigation of prodromal features in metabolic syndrome based on transcriptome analysis
SM Park, M Park, HJ Ban, SJ Baek, SY Kim, S Lee, HJ Jin
Genes & Diseases, 10.3 (2023): 708-711.
Bojungikki-Tang Enhances the Effect of PD-1 Blockade in a Syngeneic Murine Model of Lung Carcinoma
J Chun, HN Kang, JM Yi, SH Hong, SM Park, MK Jeong
Processes, 10 (9), 1683
Investigating treatment response and immune profile in association with pattern identification in NSCLC patients scheduled for immune checkpoint inhibitor monotherapy (HARMONY study): A protocol for a prospective observational study
JH Jang, HJ Jun, Y Choi, JC Kim, H Jang, SM Park, O Kwon, CM Choi, et. al
Medicine: Case Reports and Study Protocols, 3(8), e0247.
J Chun, SM Park, JM Yi, IJ Ha, HN Kang, MK Jeong
Frontiers in pharmacology 13, 901563
Reported in the media "YTN".
Systematic Analysis of the Molecular Mechanisms of Cold and Hot Properties of Herbal Medicines
SM Park, SJ Baek, HJ Ban, HJ Jin, S Cha
Plants, 11 (7), 997
Selected as "Editor’s Choice".
SJ Baek, H Lee, SM Park, M Park, JM Yi, NS Kim, A Kim, S Cha
Biomedicine & Pharmacotherapy, 148, 112748
SJ Baek, HJ Ban, SM Park, SY Kim, S Lee, HJ Jin
Genes & Diseases, 9 (4), 833
SH Lee§, SM Park§, SS Yeo, O Kwon, MK Lee, H Yoo, EK Ahn, JY Jang, JH Jang
Diagnostics 12 (1), 112
2021
SM Park, A Kim, G Park, O Kwon, S Park, H Yoo, JH Jang
Diagnostics 11 (9), 1697
CY Hwang§, SJ Yu§, JK Won§, SM Park§, H Noh, S Lee, EJ Cho, JH Lee, et. al
Cancer Gene Therapy, 1-14
Circulating microRNAs as Potential Diagnostic Biomarkers for Poor Sleep Quality
SJ Baek, HJ Ban, SM Park, B Lee, Y Choi, Y Baek, S Lee, S Cha
Nature and Science of Sleep 13, 1001
2020
SM Park§, CY Hwang§, J Choi, CY Joung, KH Cho
Oncogene 39 (19), 3803-3820
Realizing cancer precision medicine by integrating systems biology and nanomaterial engineering
JI Joo, M Choi, SH Jang, S Choi, SM Park, D Shin, KH Cho
Advanced Materials 32 (35), 1906783
Selected as a cover paper Inside Back Cover (doi.org/10.1002/adma.202070265).
2019
SM Park§, CY Hwang§, SH Cho, D Lee, JR Gong, S Lee, S Nam, KH Cho
The FEBS journal 286 (7), 1305-1318
(*Co-first author)
Selected as a cover paper of April issue in 2019 (doi.org/10.1111/febs.14540).
A Commentary on this paper was published in The FEBS Journal (doi.org/10.1111/febs.14809).
Locally activating TrkB receptor generates actin waves and specifies axonal fate
D Woo, Y Seo, H Jung, S Kim, N Kim, SM Park, H Lee, S Lee, KH Cho, WD Heo
Cell chemical biology 26 (12), 1652-1663. e4
Selected as a cover paper of December issue in 2019 (on the cover).
Previewed by Michael Z. Lin in Cell Chemical Biology (doi.org/10.1016/j.chembiol.2019.12.003).
Minimal intervening control of biomolecular networks leading to a desired cellular state
SM Choo§, SM Park§, KH Cho
Scientific reports 9 (1), 1-15
2013 - 2018
JK Won, SJ Yu, CY Hwang, SH Cho, SM Park, K Kim, WM Choi, H Cho, et. al
Hepatology 66 (3), 855-868
Cancer reversion, a renewed challenge in systems biology
KH Cho, S Lee, D Kim, D Shin, JI Joo, SM Park
Current Opinion in Systems Biology 2, 49-58
Attractor landscape analysis of colorectal tumorigenesis and its reversion
SH Cho, SM Park, HS Lee, HY Lee, KH Cho
BMC systems biology 10 (1), 1-13
SM Park, SY Shin, KH Cho
Plos one 11 (9), e0162153
The reverse control of irreversible biological processes
KH Cho, JI Joo, D Shin, D Kim, SM Park
Wiley Interdisciplinary Reviews: Systems Biology and Medicine 8 (5), 366-377
Discovery of a kernel for controlling biomolecular regulatory networks
J Kim, SM Park, KH Cho
Scientific reports 3 (1), 1-9