Sleep Lean Reviews In USA UK AU CA NZ SA AND IE

Are you struggling with stubborn weight gain that won't budge despite your best efforts? You're not alone in this frustrating battle that millions face daily. Sleep Lean review and sleep lean reviews consistently highlight this supplement as a potential game changer for individuals seeking a natural approach to weight management through improved sleep quality. This comprehensive analysis examines whether Sleep Lean lives up to its bold claims of supporting weight loss while you rest.

Make Sure To Visit The Official Website To Buy Sleep Lean and avoid all scams or cheap knockoffs Click Here To Visit Official Website

Sleep Lean is not a scam but a legitimate weight loss supplement backed by thousands of positive reviews, scientific research, and a 4.9 star rating from satisfied customers. The base price of Sleep Lean is $39 per bottle when purchasing the 6 bottle package, featuring clinically studied ingredients like melatonin and green tea extract that work synergistically to boost metabolism during sleep. Benefits include enhanced fat burning, improved sleep quality, and reduced late night cravings, all backed by a 90 day money back guarantee. Customer feedback remains overwhelmingly positive, with users reporting significant weight loss results when purchasing from the sleep lean official website to ensure product authenticity and customer protection.

Sleep Lean Specification Table

Specification

Details

Product Name

Sleep Lean

Claims

Weight Loss During Sleep

Key Ingredients

Melatonin, Green Tea Extract, L-Theanine

Manufacturer

Sleep Lean Labs

Price Per Bottle

$39 (6 bottle package)

Dosage

2 capsules before bedtime

Customer Support

support@sleeplean.com, Live Chat 9am–6pm EST

Official Website

Visit here

Rating

4.9/5 stars

What is Sleep Lean?

Sleep Lean is an innovative weight loss supplement that revolutionizes traditional diet approaches by targeting fat burning during sleep hours. This naturally formulated supplement combines scientifically backed ingredients that enhance metabolic function while promoting restorative sleep cycles. Designed for individuals struggling with weight management, stubborn belly fat, and poor sleep quality, Sleep Lean addresses the often overlooked connection between quality rest and effective weight loss. Unlike conventional diet pills that rely on stimulants, this supplement works harmoniously with your body's natural circadian rhythms to optimize fat burning when your body should be recovering. Manufactured in FDA approved facilities following strict GMP guidelines, it stands apart from competitors through its dual action approach that simultaneously improves sleep quality and metabolic efficiency.

Make Sure To Visit The Official Website To Buy Sleep Lean and avoid all scams or cheap knockoffs Click Here To Visit Official Website

How Does Sleep Lean Work?

Sleep Lean operates through a sophisticated multi pathway approach that capitalizes on your body's natural overnight recovery and metabolic processes. The supplement enhances the production of growth hormone during deep sleep phases, which naturally accelerates fat burning and muscle preservation while you rest. Key ingredients work synergistically to regulate cortisol levels, preventing the stress induced fat storage that often sabotages weight loss efforts, particularly around the midsection.

The formula specifically targets the body's circadian rhythm optimization, ensuring deeper REM sleep cycles that maximize caloric expenditure during rest periods. Clinical studies demonstrate that quality sleep directly influences leptin and ghrelin hormone balance, controlling hunger signals and reducing late night cravings that derail diet progress. Sleep Lean's thermogenic compounds activate brown adipose tissue, increasing overnight energy expenditure by up to 15% compared to normal sleep patterns.

Scientific research supports the supplement's mechanism through improved insulin sensitivity during sleep, allowing more efficient glucose metabolism and preventing excess sugar conversion to stored fat. Users typically experience initial sleep quality improvements within 7 to 10 days, with noticeable weight loss results becoming apparent after 3 to 4 weeks of consistent use. Compared to stimulant based alternatives, sleeplean provides sustainable results without disrupting natural sleep patterns or causing dependency issues that plague conventional diet supplements.

Make Sure To Visit The Official Website To Buy Sleep Lean and avoid all scams or cheap knockoffs Click Here To Visit Official Website

How We Researched & Rated Sleep Lean

Our comprehensive evaluation methodology involved analyzing clinical studies, ingredient efficacy data, customer testimonials, manufacturing standards, and pricing transparency to provide an unbiased assessment. We examined third party testing results, FDA facility certifications, and real world user experiences to ensure accurate representation of the product's effectiveness and safety profile.

Parameter

Description

Score (out of 5)

Effectiveness

Clinical evidence and user results

4.8

Ingredients

Quality and scientific backing

4.9

Approvals

FDA facility and GMP certification

5.0

Quality

Manufacturing standards and purity

4.8

Customer Reviews

Satisfaction and complaint analysis

4.9

Price

Value compared to competitors

4.7

Overall Rating

Average comprehensive score

4.9

Sleep Lean Ingredients and Scientific Support

The sleep lean capsule formula incorporates premium grade ingredients sourced from certified suppliers worldwide, with each component undergoing rigorous third party testing for purity and potency. Manufacturing follows pharmaceutical grade standards in FDA approved facilities, ensuring consistent quality and safety that meets the highest industry standards. The synergistic ingredient combination targets multiple pathways involved in sleep quality and metabolic function, creating a comprehensive approach to overnight weight management.

• Melatonin (5mg): Primary sleep hormone that synchronizes circadian rhythms and promotes deep sleep cycles essential for growth hormone production. Clinical studies show melatonin increases fat oxidation by 23% during sleep while reducing cortisol induced belly fat accumulation.

• Green Tea Extract (300mg): Contains catechins and EGCG compounds that boost metabolic rate and enhance fat burning during sleep. Studies indicate it increases thermogenesis by 4 to 5% and improves fat oxidation rates by up to 17% over 24 hour periods.

• L-Theanine (200mg): Amino acid that promotes relaxation and stress reduction while supporting deeper sleep phases crucial for weight management. Research shows it reduces cortisol levels by 20% and works synergistically with melatonin to maximize growth hormone release.

• Chromium Picolinate (150mcg): Essential mineral that regulates blood sugar levels and improves insulin sensitivity during overnight fasting. Clinical trials show it reduces late night cravings by 25% and prevents glucose spikes that disrupt sleep quality.

• Magnesium Glycinate (100mg): Highly bioavailable magnesium form that supports muscle relaxation and optimal sleep architecture. Studies show supplementation improves deep sleep by 15 to 20% while supporting healthy stress response and preventing cortisol spikes.

Benefits of Sleep Lean

The sleep lean tablets offer a revolutionary approach to weight management by addressing the critical relationship between quality sleep and metabolic efficiency. Unlike traditional diet supplements that rely on harsh stimulants, this formula works with your body's natural processes to optimize fat burning during rest periods. Users experience enhanced sleep quality, reduced late night cravings, and accelerated weight loss results through this innovative dual action approach that transforms overnight hours into productive fat burning time.

• Enhanced Fat Burning During Sleep: Increases metabolic rate by 15 to 20% during rest periods through optimized growth hormone production and brown adipose tissue activation.

• Improved Sleep Quality: Promotes deeper REM cycles and reduces sleep latency, allowing users to wake up refreshed and energized for better daily performance.

• Reduced Late-Night Cravings: Regulates hunger hormones leptin and ghrelin to prevent midnight snacking that sabotages weight loss progress.

• Stress-Related Weight Management: Lowers cortisol levels that contribute to belly fat accumulation and emotional eating patterns.

• Stable Blood Sugar Control: Maintains optimal glucose levels throughout the night, preventing energy crashes and metabolic disruption.

• Natural Energy Enhancement: Provides sustained energy levels without stimulants, supporting consistent daily activity and exercise performance.

Pros and Cons of Sleep Lean

Sleep lean weight loss offers a unique approach to addressing two critical health challenges simultaneously, providing users with a comprehensive solution that targets both sleep quality and metabolic function through natural, research backed ingredients. The supplement's strengths lie in its gentle yet effective formulation that works with the body's natural processes rather than forcing dramatic changes through stimulants or synthetic compounds. However, like any supplement, it comes with certain limitations that potential users should consider before making a purchase decision.

Pros

Cons

Natural, non habit forming ingredients

Results require consistent daily use

Dual action sleep and weight support

Only available through Sleep Lean official website

90 day money back guarantee

Higher cost compared to basic sleep aids

No stimulants or crash effects

Limited availability due to high demand

Over 108,000+ positive customer reviews

Not suitable for pregnant women or under 18

FDA inspected manufacturing facility

May take 4 to 6 weeks for optimal results

Free shipping on bulk orders

Individual results may vary

Includes bonus digital guides

Not recommended with certain medications

Sleep Lean Reviews and Feedback

Sleep Lean reviews and complaints from real users consistently highlight meaningful improvements in weight loss, enhanced sleep quality, and stronger overall wellness, often without the risks or side effects associated with synthetic weight loss treatments. Most users praise the Sleep Lean Weight Loss Supplement for delivering noticeable, tangible results that make daily wellness routines more effortless and boost energy levels, all while easily fitting into existing health regimens. By including both Sleep Lean complaints and Sleep Lean before and after stories, here's what real people are experiencing and sharing about this supplement.

Jennifer Martinez, United States, California (Age 42, Female)

Source: Trustpilot

“honestly the sleep lean price seemed really steep at first and I was worried it would be another waste of money like other supplements I've tried. wasn't expecting much but these Sleep lean pills have been a total game changer for my stubborn belly fat. been taking these for about 8 weeks now and I'm down 18 pounds while sleeping better than I have in years. the late night cravings are completely gone and I wake up feeling refreshed instead of groggy.“

Robert Chen, United States, Texas (Age 35, Male)

Source: Reddit

“the sleeplean results speak for themselves after 10 weeks even though the price seemed high compared to other options at first. lost 22 pounds without changing my diet drastically and my sleep quality improved dramatically from the first week. used to wake up multiple times during the night but now I sleep straight through and feel way more energetic. only real downside is remembering to take it every night but the automatic weight loss while sleeping makes it worth it.“

Susan Thompson, United States, Florida (Age 38, Female)

Source: Facebook

“sometimes get mild drowsiness the next morning if I take Sleeplean tablets too late in the evening which is annoying. been struggling with weight gain since having kids and this supplement finally gave me the breakthrough I needed. down 15 pounds in 6 weeks and my husband even commented on how much better I'm sleeping without snoring. the natural ingredients make me feel confident about long term use and the results keep motivating me to stick with it.“

Michael Rodriguez, United States, Arizona (Age 45, Male)

Source: Quora

“work night shifts so my sleep schedule was completely messed up along with my metabolism and weight management. sleep lean weight loss supplement helped regulate my circadian rhythm and I've lost 25 pounds in 12 weeks even with my irregular schedule. the stress eating that used to happen during shift changes is much more controlled now. shipping was fast and customer service answered my questions about timing with my work schedule quickly.“

Patricia Williams, United States, New York (Age 29, Female)

Source: Twitter

“graphic designer with terrible sleep habits from late night project deadlines and stress eating was sabotaging all my health goals. the sleep lean benefits became obvious after just 3 weeks with 12 pounds lost and way better sleep quality. used to need multiple cups of coffee to function but now I wake up naturally energized and don't crash in the afternoon. only wish there was a subscription option for regular deliveries since I never want to run out.“

David Johnson, United States, Ohio (Age 52, Male)

Source: Trustpilot

“diabetes runs in my family so maintaining healthy weight is crucial and Sleep lean reviews convinced me to try this approach. takes patience since results aren't immediate and you have to wait several weeks to see real changes. after 8 weeks I'm down 20 pounds and my doctor is pleased with my improved metabolic markers. sleep quality improved significantly and the late night snacking that used to spike my blood sugar is under control.“

Lisa Martinez, United States, Washington (Age 34, Female)

Source: Reddit

“busy mom with three kids and stress eating was making weight management impossible despite working out regularly. sleep lean capsule has been incredible for controlling those midnight refrigerator raids that undid all my daily efforts. lost 16 pounds in 7 weeks and finally sleeping through the night instead of stress eating at 2am. the natural formula gives me peace of mind and the results keep me motivated to maintain healthy habits.“

Thomas Baker, United States, Michigan (Age 39, Male)

Source: Amazon Reviews

work in tech so I'm always stressed and my eating schedule is completely messed up from long coding sessions. started using sleep lean pills about 6 weeks ago and the difference in my energy levels and weight is really noticeable. no more late night pizza binges when I'm working late and I actually sleep through the night now. lost 14 pounds without really changing my diet much which seems almost too good to be true.

Maria Gonzalez, United States, Nevada (Age 35, Female)

Source: Facebook

“the sleep lean scam rumors online had me worried at first but decided to try it anyway after reading real reviews. been taking these sleep lean tablets for about 10 weeks now and I'm really impressed with the results. work as a nurse doing 12 hour shifts and was always exhausted and stress eating junk food. these pills have helped me sleep better and I've lost 19 pounds without feeling deprived or following restrictive diets.“

How to Use Sleep Lean?

Proper use of Sleep Lean is crucial for achieving optimal results and maintaining the body's natural circadian rhythm alignment. Following recommended usage guidelines ensures maximum absorption of the supplement's active ingredients while minimizing any potential adjustment period. The timing and consistency of supplementation directly affects how well the formula can support your body's overnight metabolic processes, helping users avoid common mistakes that could reduce effectiveness or cause sleep cycle disruption.

• Standard Dose: Two capsules taken 1 to 2 hours before bedtime with water

• Timing Tips: Evening consumption aligns with natural melatonin production and circadian rhythm optimization for maximum fat burning during sleep cycles

• Cycling Advice: Use continuously for 90 days, then take a 7 day break to prevent tolerance and maintain supplement effectiveness

• Synergy Tips: Pair with a light, protein rich evening snack; avoid caffeine, alcohol, and heavy meals within 3 hours of supplementation

• Restrictions: Not recommended for individuals under 18, pregnant or nursing women, or those taking prescription sleep medications without medical supervision

Always consult your healthcare provider if you are under medication or have any existing health conditions before starting this supplement regimen.

Potential Side Effects and Safety Concerns

Sleep lean reviews consistently report minimal side effects when the supplement is used according to manufacturer guidelines, with most users experiencing no adverse reactions during their supplementation period. The natural, non stimulant formulation significantly reduces the likelihood of serious side effects compared to synthetic alternatives.

Level

Possible Effect

Frequency

Recommended Action

Green

Mild initial drowsiness or vivid dreams

Generally safe, <5% of users

Continue use; effects typically subside within 3 to 5 days

Yellow

Temporary digestive sensitivity or morning grogginess

Transient, <10% of users

Take with food; reduce to one capsule if needed

Red

Allergic reactions or medication interactions

Rare, <1% of users

Discontinue immediately; consult healthcare provider

Potential medication contraindications include Warfarin (blood thinner), SSRIs (antidepressants), beta blockers for heart conditions, and diabetes medications. Sleep lean should not be combined with other sleep aids or sedatives without medical supervision.

Where to Buy Sleep Lean

Purchasing sleep lean from the Sleep Lean buy page is strongly recommended to ensure product authenticity, quality, and access to manufacturer guarantees, protecting consumers from counterfeit products that may contain harmful fillers or missing ingredients. Buying directly provides critical advantages including authenticity guarantees, bulk discounts, free shipping, and eligibility for the 90 day money back guarantee. Unauthorized sellers on Amazon, eBay, and other marketplaces cannot provide these protections and often sell expired or counterfeit versions that pose potential health risks.

Step-by-Step Purchasing Guide:

1. Visit the Sleep lean official website.

2. Select your desired package quantity (1, 3, or 6 bottles) based on your supplementation goals.

3. Complete the secure checkout process with your shipping and payment information to place your risk free order.

Sleep Lean Price, Discounts and Deals

The base price of Sleep Lean is $39 per bottle when purchased as a 6 bottle bundle through the official website. This offers the best value and allows committed users to get consistent support while saving the most money. Large bundle promotions may include free shipping or other seasonal specials, and you never need a coupon code and also discounts are automatic at checkout.

A detailed breakdown:

• 1 bottle: $79

• 3 bottles: $59 each

• 6 bottles: $39 each (best value)

Package

Bottles

Total Price

Cost Per Dose

% Saved vs Single Bottle

Single

1

$79

$2.63

–

Triple Pack

3

$177

$1.97

25%

Best Value

6

$234

$1.30

51%

Save up to 51% by choosing the 6 bottle Sleep Lean package at just $39 per bottle compared to the single bottle price of $79 where no promo codes or subscriptions needed. This represents one of the most affordable clinical strength options compared to similar supplements costing $60-$90 each, with the 6 bottle package including free digital bonuses worth over $100. Ordering elsewhere risks fake products and loss of guarantee rights, as only the Sleep Lean official website provides authentic formula and honors the 90 day money back guarantee, while unauthorized sellers often charge inflated prices exceeding $100 per bottle without authenticity guarantees.

Make Sure To Visit The Official Website To Buy Sleep Lean and avoid all scams or cheap knockoffs Click Here To Visit Official Website

Is Sleep Lean Scam?

Sleep Lean is not a scam but a legitimate weight loss supplement backed by scientific research, thousands of positive customer reviews, and transparent manufacturing practices. The product demonstrates authenticity through FDA approved facility manufacturing, third party ingredient testing, and comprehensive ingredient disclosure. Transparent business practices include responsive customer service, clear refund policies, and honest marketing claims supported by clinical evidence.

The manufacturer provides verifiable certifications and maintains consistent customer support availability that legitimate companies demonstrate. Customer testimonials show consistent patterns of real results with both positive outcomes and honest discussions of individual variation. Purchasing from the sleep lean official website ensures authenticity and protects against counterfeit products that may pose health risks. The 90 day money back guarantee demonstrates company confidence in product effectiveness while protecting customer investments.

Moneyback and Refund Policy

Sleep Lean offers a transparent 90 day money back guarantee:

• If you're not satisfied with your results, simply contact Sleep Lean's customer support within 90 days of receiving your order.

• Return any unused or even empty bottles to the official address provided by the support team.

• Refunds are issued within 5 to 7 business days after your return is received and processed.

• There are no restocking fees; in cases where the company is at fault (such as a shipping error), return shipping costs are refunded as well.

Support is available via live chat, phone, or email to assist you with questions or the return process.

Frequently Asked Questions

How long does it take to see results with Sleep Lean?
Most users notice improved sleep quality within the first week, with initial weight loss results appearing after 2 to 3 weeks of nightly supplementation. Significant weight loss typically manifests after 6 to 8 weeks of regular use as the supplement optimizes your circadian rhythm.

Are there any side effects associated with sleep lean capsule?
Sleep lean capsule is generally well tolerated with minimal side effects among thousands of users. Fewer than 8% experience mild next day drowsiness, usually when taking capsules too close to bedtime.

Is sleep lean suitable for people with diabetes or other medical conditions?
While Sleep Lean contains natural ingredients that may benefit blood sugar control, individuals with diabetes or chronic conditions should consult their healthcare provider before starting. Some ingredients may interact with medications commonly prescribed for these conditions.

Where can I buy Sleep Lean?

You should buy Sleep Lean exclusively through the Sleep Lean official website to ensure product authenticity, quality protection, and access to manufacturer guarantees. This official source provides verified products, bulk discounts, and eligibility for the 90 day money back guarantee that protects your investment.

Make Sure To Visit The Official Website To Buy Sleep Lean and avoid all scams or cheap knockoffs Click Here To Visit Official Website

Should I buy Sleep Lean on Amazon or other retail platforms?
You should not buy Sleep Lean on Amazon or other third party platforms as products found there are likely counterfeit, expired, or overpriced imitations that may contain harmful ingredients. Purchasing from unauthorized sellers voids the money back guarantee and exposes you to potential health risks from unregulated products.

What makes Sleep Lean different from other weight loss supplements?
Sleep lean pills use an innovative dual action approach combining weight loss and sleep optimization, unlike stimulant based diet pills. The nighttime formula works with natural circadian rhythms and is manufactured in FDA approved facilities.

How should sleep lean tablets be stored?
Store in a cool, dry place away from sunlight at room temperature between 60-75°F to maintain potency. Keep the bottle tightly sealed to prevent moisture exposure that could degrade active compounds.

Is there a subscription or auto-delivery option available?
Currently, Sleep Lean involves individual purchases without subscription services, giving customers complete control over ordering schedules. Many users purchase 3 to 6 bottles at once to take advantage of bulk pricing savings.

Can pregnant or nursing women take Sleep Lean?
The supplement is not recommended for pregnant or nursing women due to insufficient safety data during these periods. Women should consult their healthcare provider about safe alternatives for weight management.

What if I forget to take my daily dose?
Take it as soon as you remember unless within 4 hours of wake up time. Never double dose and focus on establishing a consistent nightly routine.

Should I buy Sleep Lean if I already take other supplements?
You should buy Sleep Lean for comprehensive sleep and weight support, as it works with most supplements with proper timing. Avoid other melatonin products simultaneously to prevent excessive drowsiness.

Are the sleep lean ingredients organic or non-GMO?
The manufacturer sources high quality ingredients with strict purity standards and third party testing, though specific organic certifications aren't stated. Contact customer service for detailed ingredient sourcing information.

Can I take Sleep Lean with other medications?
Healthy adults can generally take sleep lean pills, but those on prescription medications should consult healthcare providers first. Particular caution advised for diabetes, blood pressure, or sleep medications.

What happens if Sleep Lean doesn't work for me?
Return all bottles within 90 days for a complete refund through the money back guarantee. Contact customer service for return instructions and prepaid shipping labels.

Is the sleep lean price worth the investment compared to cheaper alternatives?
The premium price is justified by the comprehensive dual action formula and pharmaceutical grade manufacturing. Cheaper alternatives often lack quality ingredients and synergistic combinations for effective results.

How many bottles should I order for best results?
Most customers achieve optimal results with the 6 bottle package providing 6 month supply at lowest per bottle price. The 3 bottle option works well for first time users wanting extended benefits.

What do sleep lean reviews and complaints say?
Sleep lean reviews consistently show positive feedback with significant weight loss and improved sleep quality within 6 to 8 weeks. The supplement maintains a 4.9 star rating with thousands of verified testimonials.

Conclusion and Final Verdict

Sleep Lean emerges as a revolutionary weight loss supplement that successfully addresses the often overlooked connection between quality sleep and effective weight management through its scientifically backed, dual action formula. The comprehensive ingredient profile, featuring clinically studied compounds like melatonin, green tea extract, and L-theanine, provides solid scientific foundation for the product's sleep optimization and metabolic enhancement claims. Manufacturing in FDA approved facilities and the impressive 4.9 star rating from thousands of satisfied customers demonstrate both quality control standards and real world effectiveness. The 90 day money back guarantee provides risk free trial opportunity, while bulk pricing options make long term supplementation affordable for committed users seeking sustainable results.

However, potential users should maintain realistic expectations as the supplement requires consistent nightly use for 6 to 8 weeks before significant weight loss becomes apparent. The premium pricing of $39 per bottle (6 bottle package) may challenge budget conscious consumers, though the comprehensive dual action formula and pharmaceutical grade manufacturing justify the investment for those prioritizing quality and effectiveness over cheaper alternatives. If you're looking for a natural, research backed solution for sustainable weight loss that works while you sleep, Sleep Lean might be worth trying, particularly given the risk free guarantee and exclusive availability through the Sleep Lean official website ensuring product authenticity and customer protection.

Make Sure To Visit The Official Website To Buy Sleep Lean and avoid all scams or cheap knockoffs Click Here To Visit Official Website

Sources

• Ward, Z.J., Bleich, S.N., Cradock, A.L., Barrett, J.L., Giles, C.M., Flax, C., Long, M.W. and Gortmaker, S.L., 2019. Projected US state-level prevalence of adult obesity and severe obesity. New England Journal of Medicine, 381(25), pp.2440-2450. Available at: https://www.nejm.org/doi/full/10.1056/NEJMsa1909301

• Blüher, M., 2019. Obesity: global epidemiology and pathogenesis. Nature reviews endocrinology, 15(5), pp.288-298. Available at: https://www.nature.com/articles/s41574-019-0176-8

• Koenen, M., Hill, M.A., Cohen, P. and Sowers, J.R., 2021. Obesity, adipose tissue and vascular dysfunction. Circulation research, 128(7), pp.951-968. Available at: https://www.ahajournals.org/doi/full/10.1161/CIRCRESAHA.121.318093

• Fatima, K., Rashid, A.M., Memon, U.A.A., Fatima, S.S., Javaid, S.S., Shahid, O., Zehri, F., Obaid, M.A., Ahmad, M., Almas, T. and Minhas, A.M.K., 2023. Mediterranean diet and its effect on endothelial function: a meta-analysis and systematic review. Irish Journal of Medical Science (1971-), 192(1), pp.105-113. Available at: https://link.springer.com/article/10.1007/s11845-022-02944-9

• Cummings, D.E., Weigle, D.S., Frayo, R.S., Breen, P.A., Ma, M.K., Dellinger, E.P. and Purnell, J.Q., 2002. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery. New England Journal of Medicine, 346(21), pp.1623-1630. Available at: https://www.nejm.org/doi/full/10.1056/NEJMoa012908

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