Publications from IISER Pune
33. Jalwal, S.;# Sil, A.;# Singh, A.; Prodhan, S.; Sil, D.;* Chakraborty, S.* Manganese Catalyzed Selective Hydration of Nitriles to Primary Amides: Experimental and Theoretical Studies. Chem. Cat. Chem. 2026, 18, e70947 (# these authors contributed equally)
32. Jalwal, S.; Gutal, A.; Saini, R. K.; Anand, A.; Prodhan, S.; Sil, D.;* Paranjothy, M.;* Chakraborty, S.* Bioinspired Manganese Catalyzed Direct Deamination of Primary Amines With Water Forming Carboxylic Acids and Ketones. Chem. Eur. J 2026, 32, e70774
31. Atreya, V.; Sil, A.; Sil, D.;* Chakraborty, S.* Molybdenum Catalyzed Acceptorless Dehydrogenative Approach for Quinoline Synthesis Using Amino Alcohol. Org. Biomol. Chem. 2025, 23, 10118-10126
30. Anand, A.; Regina, A.; Jalwal, S.; Pradhan, S.; Sil, D.;* Paranjothy, M.;* Chakraborty, S.* Chromium Catalyzed Acceptorless Dehydrogenative (Cross)Coupling of Primary Amines to Secondary Imines. Dalton Trans. 2025, 54, 6432-6442
Prior to joining IISER Pune
29. Wenger, E. S.; Martinie, R. J.; Ushimaru, R.; Pollock, C. J.; Sil, D.; Li, A.; Hoang, N.; Palowitch, G.; Graham, B.; Schaperdoth, I. ; Burke, E.; Maggiolo, A.; Chang, W. -C.; Allen, B.; Krebs, C.;* Silakov, A.;* Boal, A.;* Bollinger, J. M.,Jr.* Optimized Substrate Positioning Enables Switches in C–H Cleavage Site and Reaction Outcome in the Hydroxylation-Epoxidation Sequence Catalyzed by Hyoscyamine 6β-Hydroxylase. J. Am. Chem. Soc 2024, 146, 24271-24287
28. Pan, J.; Wenger, E. S.; Lin, C. -Y.; Zhang, B.; Sil, D.; Schaperdoth, I.; Saryazdi, S.; Grossman, R. B.; Krebs, C.;* Bollinger, J. M., Jr.* An Unusual Ferryl Intermediate and Its Implications for the Mechanism of Oxacyclization by the Loline-Producing Iron(II)- and 2-Oxoglutarate-Dependent Oxygenase, LolO . Biochemistry 2024, 63, 1674–1683
27. Slater, J. W.;* Lin, C. -Y.; Neugebauer, M.; McBride, M. J.; Sil, D.; Nair, M. A.; Katch, B. Y.; Boal, A. K.; Chang, M. C. Y.; Silakov, A.; Krebs, C.;* Bollinger, J. M., Jr.* Synergistic Binding of the Halide and Cationic Prime Substrate of the L-Lysine 4-Chlorinase, BesD, in Both Ferrous and Ferryl States . Biochemistry 2023, 62, 2480-2491
26. McBride, M. J.; Pope, S. R.; Nair, M. A.; Sil, D.; Salas-Solá, X. E.; Krebs, C.; Bollinger, J. M., Jr.; Boal, A. K.* Methods for Biophysical Characterization of SznF, a Member of the Heme-Oxygenase-Like Diiron Oxidase/Oxygenase Superfamily in "Oxygen Sensing. Methods in Molecular Biology" ed Weinert, E. E. – Springer, New York, 2023, 2648, 123-154
25. Sil, D.; Khan, F. S. T.; Rath, S. P.* Effect of intermacrocyclic interactions: modulation of metal spin state in oxo/hydroxo/fluoro bridged diiron(III)/dimanganese(III) porphyrin dimers. Advances in Inorganic Chemistry 2023, 81, 95-184
24. Dong, H. T.; Camarena, S.; Sil, D.; Lengel, M. O.; Zhao, J.; Hu, M. Y.; Alp, E. E.; Krebs, C.; Lehnert, N.* What Is the Right Level of Activation of a High-Spin {FeNO}7 Complex to Enable Direct N–N Coupling? Mechanistic Insight into Flavodiiron NO Reductases. J. Am. Chem. Soc. 2022, 144, 16395-16409
23. Neti, S. S.; Sil, D.; Warui, D.; Esakova, O.; Solinski, A.; Serrano, D.; Krebs, C.;* Booker, S.* Characterization of LipS1 and LipS2 from Thermococcus kodakarensis: Proteins Annotated as Biotin Synthases, which Together Catalyze Formation of the Lipoyl Cofactor . ACS Bio & Med Chem Au 2022, 2, 509-520
22. Warui, D.; Sil, D.; Lee, K. -H.; Neti, S. S.; Esakova, O.; Knox, H.; Krebs, C.;* Booker, S.*
In vitro Demonstration of Human Lipoyl Synthase (LIAS) Catalytic Activity in the Presence of NFU1 . ACS Bio & Med Chem Au 2022, 2, 456-468
21. McBride, M. J.; Nair, M. A.; Sil, D.; Slater, J. W.; Neugebauer, M.; Chang, M. C. Y.;* Boal, A. K.;* Krebs, C.;* Bollinger, J. M., Jr.* A Substrate-triggered µ-Peroxodiiron(III) Intermediate in the 4-Chloro-L-Lysine-Fragmenting Heme-Oxygenase-like Diiron Oxidase (HDO) BesC: Substrate Dissociation from, and C4 Targeting by, the Intermediate . Biochemistry 2022, 61, 689-702
20. Dong, H. T.; Zong, Y.; Bracken, A. J.; Lengel, M. O.; Sil, D.; Krebs, C.; Lehnert, N.* Synthesis and Characterization of a Model Complex for Flavodiiron NO Reductases That Stabilizes a Diiron Mononitrosyl Complex . J. Inorg. Biochem. 2022, 229, 111723
19. Maio, N.; LaFont, B.; Sil, D.; Li, Y.; Bollinger, J. M., Jr.; Krebs, C.; Pierson, T.; Holland, S.; Linehan, M. W.; Rouault, T. A.* Fe-S cofactors in the SARS-CoV-2 RNA-dependent RNA polymerase are potential antiviral targets . Science 2021, 373, 236-241
18. Sil, D.; Banerjee, S.; Ghosh, S. K.; Rath, S. P.* Fluoro-bridged dimanganese(III) porphyrin dimer: effect of intermacrocyclic interactions in modulating metal spin state. J. Porphyr. Phthalocyanines 2021, 25, 522-532
17. Liu, G.; Sil, D.; Tong, W. -H.; Maio, N.; Bollinger, J. M., Jr.; Krebs, C.;* Rouault, T. A.* Heme biosynthesis depends on previously unrecognized acquisition of iron-sulfur cofactors in human amino-levulinic acid dehydratase. Nat. Commun. 2020, 11, 6310-6320
16. McBride, M. J.; Sil, D.; Ng, T. L.; Crooke, A. M.; Kenney, G. E.; Tysoe, C. R.; Zhang, B.; Balskus, E. P.;* Boal, A. K.;* Krebs, C.;* Bollinger, J. M., Jr.* A peroxodiiron(III) intermediate mediating both N-hydroxylation steps in biosynthesis of the N-nitrosourea pharmacophore of streptozotocin by SznF . J. Am. Chem. Soc. 2020, 142, 11818-11828
15. Dong, H.; Speelman, A. L.; Kozemchak, C. E.; Sil, D.; Krebs, C.; Lehnert, N.* The Fe2(NO)2 Diamond Core: A Unique Structural Motif in Non-Heme Iron-NO Chemistry. Angew. Chem. Int. Ed. 2019, 58, 17695-17699
14. Kumar, A.; Sil, D.; Usman, M.; Rath, S. P.* Dimanganese(III) porphyrin dication diradical and its transformation to a μ-hydroxo porphyrin-oxophlorin heterodimer. Chem. Commun. 2019, 55, 1588-1591
13. Sil, D.; Martinez, Z.; Ding, S.; Bhuvanesh, N.; Darensbourg, D. J.; Hall, M. B.;* Darensbourg, M. Y. * Cyanide Docking and Linkage Isomerism in Models for the Artificial [FeFe]-Hydrogenase Maturation Process . J. Am. Chem. Soc. 2018, 140, 9904-9911
12. Sil, D.; Dey, S.; Kumar, A.; Bhowmik, S.; Rath, S. P.* Oxidation triggers extensive conjugation and unusual stabilization of two di-heme dication diradical intermediates: role of bridging group for electronic communication. Chem. Sci. 2016, 7, 1212-1223 (Edge Article)
11. Dey, S.; Sil, D.; Rath, S. P.* A highly oxidized cobalt porphyrin dimer: spin coupling and stabilization of the four-electron oxidation product. Angew. Chem. Int. Ed. 2016, 55, 996-1000
10. Sil, D.; Kumar, A.; Rath, S. P.* Diiron(III)-μ-fluoro bisporphyrins: effect of bridging ligand on the metal spin state. Chem. Eur. J. 2016, 22, 11214-11223 (Hot Paper; Highlighted as a Frontispiece)
9. Sil, D.; Khan, F. S. T.; Rath, S. P.* Effect of inter-porphyrin distance on spin-state in diiron(III)-μ-hydroxo bisporphyrins . Chem. Eur. J. 2016, 22, 14585-14597
8. Sil, D.; Bhowmik, S.; Khan, F. S. T.; Rath, S. P.* Experimental and theoretical investigation on a series of novel dimanganese(III)-μ-hydroxo bisporphyrins: magneto-structural correlation and effect of metal spin on porphyrin core deformation . Inorg. Chem. 2016, 55, 3239-3251
7. Dey, S.; Sil, D.; Pandit, Y.; Rath, S. P.* Effect of two interacting rings in metalloporphyrin dimers upon stepwise oxidations . Inorg. Chem. 2016, 55, 3229-3238
6. Sil, D.; Rath, S. P.* Ethane-bridged porphyrin dimer as model of di-heme proteins: inorganic and bioinorganic perspectives and consequences of heme-heme interactions . Dalton Trans. 2015, 44, 16195-16211 (Perspective Article)
5. Sainna, M. A.; Sil, D.; Sahoo, D.; Martin, B.; Rath, S. P.;* Comba , P.;* de Visser, S. P.* Spin state ordering in hydroxo bridged diiron(III)bisporphyrin complexes . Inorg. Chem. 2015, 54, 1919-1930
4. Sil, D.; Khan, F. S. T.; Rath, S. P.* Axial thiophenolate coordination on diiron(III)bisporphyrin: influence of heme-heme interactions on structure, function and electrochemical properties of the individual heme center . Inorg. Chem. 2014, 53, 11925-11936
3. Ghosh, S. K.; Bhowmik, S.; Sil, D.; Rath, S. P.* Effect of heme-heme interactions and modulation of metal spins by counter anions in a series of diiron(III)-μ-hydroxo bisporphyrins: unusual stabilization of two different spins in a single molecular framework . Chem. Eur. J. 2013, 19, 17846-17859
2. Patra, R.; Sahoo, D.; Dey, S.; Sil, D.; Rath, S. P.* Switching orientation of two axial imidazole ligands between parallel and perpendicular in low-spin Fe(III) and Fe(II) nonplanar porphyrinates . Inorg. Chem. 2012, 51, 11294-11305
1. Bhowmik, S.; Sil, D.; Patra, R.; Rath, S. P.* Axial phenoxide coordination on diiron(III)bisporphyrin: insights from experimental and DFT studies . J. Chem. Sci. 2011, 123, 827-837