We are interested in functionally studying novel regulators that regulate cellular plasticity and transcriptional heterogeneity in normal mammary epithelial cells and breast cancer. Our workflow uses a combination of single cell technologies, computational methods and organoid assays. 

We are interested in studying how pregnancy alters the aging process of mammary epithelial cells to reduce the long-term risk of developing breast cancer. We use a combination of single cell technologies, in vivo mouse models and organoid assays to address these questions.