Fibrous Dysplasia - A Condition to Watch Out For

Fibrous dysplasia is a rare orthopedic condition that is characterized by the growth of fibrous tissue in place of normal bone. It is a genetic condition but is not known to pass from mother to child. The abnormal growth of bone tissue results in the weakening of bones and hence, they can get fractured easily or deformed. If the fracture is serious or deformity is highly evident, surgical intervention involving orthopedic implants to correct deformity or fracture may be required.

Siora Surgicals is known to offer international standard quality orthopedic devices that are used to fix various orthopedic conditions. The company is counted among reliable Orthopedic Implants Manufacturers in India.

Types of Fibrous Dysplasia

The major classification of fibrous dysplasia includes:

Monostotic Fibrous Dysplasia

This is the commonest of two and the least complicated form of fibrous dysplasia. In this condition, only one bone gets affected. The commonly affected bones in this case include:

• Any facial bone

• Femur

• Tibia

• Rib cage

Polyostotic Fibrous Dysplasia

This type of condition is more serious when compared to monostotic fibrous dysplasia as it involves multiple bones. Here, any of the bones could get affected and it is not a guarantee that they will be on the same side. This condition generally affects younger and may involve more than half of the bones of the entire skeleton. Symptoms seen in this case may include:

• Bone deformity

• Fractures

• Skin lesions

• Different leg lengths

Monostotic Fibrous Dysplasia

This one is the severest of all as in this case, the whole skeleton becomes affected. Also known as McCune-Albright Syndrome, abnormalities of the endocrine system may also be noticed in this form of fibrous dysplasia. Some other symptoms of this condition may involve:

• Skin pigmentation

• Premature puberty

• Hyperthyroidism and hyperparathyroidism

• Short stature

• Cushing’s syndrome

• Vitamin D-resistant rickets

Common Symptoms Associated with Fibrous Dysplasia

Though the symptoms of fibrous dysplasia vary according to type and severity of the condition yet, some common symptoms that may be noticed include:

• Pain in the bones present in the affected area

• Inability or difficulty in walking

• Limb length discrepancies

• Skin pigmentation

Cause of Fibrous Dysplasia

Fibrous dysplasia is a genetic condition that results due to mutation at chromosome 20 of the gene that is involved in the production of bone tissues and growth. The mysterious thing here is that despite many studies, the exact reason for gene mutation is still unknown. It is said that the mutation generally occurs after conception during the early developmental stages of the fetus. Hence, the condition cannot pass to the children.

Diagnosis of Fibrous Dysplasia

Along with physical examination to monitor visible signs and medical history check to closely assess the condition, diagnosis of fibrous dysplasia includes certain imaging and pathological tests:

• X-ray

• MRI

• CT Scan

• Blood Tests

• Bone Scan

• Biopsy

The tests ordered will be based on the physical examination, symptoms, and medical history check of the patient.

Treatment of Fibrous Dysplasia

There are certain factors that affect the treatment of the condition, and they may include:

• The severity of the condition

• Age of the patient

• Allergies to any medicines or anesthesia

• Personal preference of the patient

Based on the above-mentioned factors, the doctor will decide the best treatment to control the condition. Here are some of the ways by which fibrous dysplasia can be treated:

• Application of orthopedic implants like metal rods to support the bone and prevent fractures

• Removal of destroyed bone and application of bone graft to fill the void

• Bone wedge removal

• Antibiotic medicines

• Physical therapy

• Pain management therapy

Siora Surgicals is crowned as a leading trauma implant manufacturer in India. The company manufactures a huge range of orthopedic devices that complies with ISO 9001:2015 and ISO 13485:2016 standards. With an aim to spread wings all around the world, Siora has also become one of the reliable Orthopedic Implants Suppliers in Malaysia with its products approved by the Malaysian Medical Device Authority.