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Due to the sheer number of possibilities, particularly if you are looking for an inexpensive solution, you could try using an on line booking service.
A small list of hotels near Sapienza University is the following:

• Ateneo Garden Palace ****

Via dei Salentini, 3, 00185 Roma RM, +39 06 444 0042

• Hotel Laurentia Roma ***

Largo degli Osci, 63, 00185 Roma RM, +39 06 445 0218

•  Hotel Villa San Lorenzo Maria ***

Via dei Liguri, 7, 00185 Roma RM, +39 06 446 9988

•  Hotel Globus ***

Viale Ippocrate, 119, 00161 Roma RM, +39 06 445 7001

The neighborhood of Sapienza is full of restaurants and places to eat. For a quick bite at lunch we suggest:

• DaMasco 

• Bar Leonardi 

• Rouge 

• Il coccodrillo 

• Ottavi 

• La Casetta 

• Ciacco 

For dinner we suggest (in a somehow descending price range):

• Said 

• Abitudini e Follie 

• Pastificio S.Lorenzo 

• Pommidoro 

• Osteria da Marcello 

• La Casetta 

• Formula 1