Shubham Misra, PhD, a clinical neuroscientist at Yale School of Medicine, led a team that evaluated data from 1951 through this year. People were over the age of 18 and had a history of ischemic stroke, hemorrhagic stroke or both. People with PSS had a significantly higher history of ischemic heart disease, prior cerebrovascular disease, atrial fibrillation and hemorrhagic transformation compared with those without PSS.  

A recently published systematic review and meta-analysis showed that post-stroke seizures (PSS) are associated with increased risk of mortality, poor functional outcomes, disability and dementia. The researchers concluded that concerted scientific efforts are needed to address these challenges, as well as additional research to understand the role of stroke severity and the location or volume of the lesion. 

In the largest meta-analysis of patients with poststroke seizures, findings showed that those with early seizures had a greater mortality risk than those with late. Led by Shubham Misra, PhD, a clinical neuroscientist at Yale School of Medicine, the analysis included data from 1951 to January 2023. The inclusion criteria comprised of patients with a history of stroke (ischemic, hemorrhagic, or both) and those aged 18 years or older presenting with either early or late PSS. Coming into the analysis, patients with PSS had a significantly higher history of ischemic heart disease (OR, 1.3; 95% CI, 1.1-1.6), prior cerebrovascular disease (OR, 1.3; 95% CI, 1.0-1.6), atrial fibrillation (OR, 1.2; 95% CI, 1.1-1.4), and the presence of hemorrhagic transformation (OR, 2.2; 95% CI, 1.6-3.0) than patients without PSS. 

Results of a new study suggest that poststroke seizures (PSSs) may be associated with significantly increased mortality and severe disability among patients with a history of stroke. This systemic review and meta-analysis was published in JAMA Neurology. 

A study conducted at AIIMS on COVID-19 patients to determine the spread of mucormycosis, commonly known as black fungus, among COVID-19 patients has revealed that patients with diabetes mellitus have higher mortality rate than the others infected by the disease.

In a systematic review and meta-analysis, researchers assessed the frequency of neurologic manifestations seen in COVID-19 patients and the association of these manifestations with COVID-19 severity and mortality.