Research

Current Research Interests:

• Mathematical oncology

• Machine Learning

Work from University of Michigan:

• "Agent-Based Modeling of Virtual Tumors Reveals the Critical Influence of Microenvironmental Complexity on Immunotherapy Efficacy" Wang, Y., Bergman, D.R., Trujillo, E., Fernald, A.A., Li, L., Pearson, A.T., Sweis, R.F. and Jackson, T.L. (2024). Cancers, 16(17), 2942.

• "Mathematical model predicts tumor control patterns induced by fast and slow cytotoxic T lymphocyte killing mechanisms"  Wang, Y., Bergman, R.D., Trujillo, E., Pearson, A.T., Sweis, R.F., Jackson, T.L. (2023). Scientific Reports, 13(1), 22541.

• "Dysregulated FGFR3 signaling alters the immune landscape in bladder cancer and presents therapeutic possibilities in an agent-based model" Bergman, R.D., Wang, Y., Trujillo, E., Li, L., Pearson, A.T., Sweis, R.F., Jackson, L.T. (2024) Frontiers in Immunology 15 (2023): 1358019

Work from University of California, Los Angeles

• "Hemodynamic-regulation allows stable growth of microvascular networks" Qi, Y., Chang, S. S.,Wang, Y., Chen, C.,Baek, K., Hsiai, T., Roper, M. (2024) Proceedings of the National Academy of Sciences.

• "Vascular Injury in the Zebrafish Tail Modulates Blood Flow and Peak Wall Shear Stress to Restore Embryonic Circular Network" Baek, K. I., Chang, S. S., Chang, C. C., Roustaei, M., Ding, Y., Wang, Y., et al. (2022) Frontiers in Cardiovascular Medicine 9.

Work from Genentech Inc. (Internship 2022 Summer)

• "A Computational Modeling Framework for In Vitro to In Vivo Translation of Drug-Induced Nephrotoxicity Based on Biomarker and Cytotoxicity Measurements in a 3-Dimensional Human Renal Proximal Tubule Microphysiological System" Huang W., Wang Y., Poon V., Tseng M., Kiyota T., Lu D. (2023) American Conference on Pharmacometrics.

Conferences and Workshops

• Joint annual meeting of the Korean Society for Mathematical Biology and the Society for Mathematical Biology, Seoul, South Korea, chair of the Mathematical Oncology contributed talk session, 07/2024

• American Association for Cancer Research Annual Meeting, 04/2024

• American Conference on Pharmacometrics, 11/2023

• National Cancer Institute Junior Investigator Meeting, awarded with travel grant, 08/2023

• Society for Mathematical Biology Annual Meeting, awarded with Landahl Travel Grant, 07/2023

• Michigan Institute for Computational Discovery and Engineering (MICDE)Annual Symposium, 04/2023

• Michigan Center for Applied and Interdisciplinary Mathematics (MCAIM) Graduate Seminar, 03/2023

• Michigan Institute for Computational Discovery and Engineering (MICDE) Graduate Seminar, 02/2023

• Physical Science of Cancer Gordon Research Seminar, awarded with travel grant, 02/2023

• Workshop on Data-Driven Mathematical & Statistical Modeling for Graduate Students, SAMSI, NSF-Duke-NCSU-UNC, 07/2021

• Computational Modelling of Cancer Biology and Treatment, University of Montreal, 07/2021