Our lab focuses on multi-disciplinary research topics, including but not limited to, sensor IC design, analog/digital/mixed-signal circuit design, biomedical applications, and Li-ion battery testing and control. We are especially interested in providing a novel platform or system to help other areas (i.e., battery production, cancer therapy, and physiological data acquisition), using CMOS fabrication technology, where billions of transistors and circuit components can be seemlessly integrated into a monolithic silicon chiplet. We focus on all the crucial areas of system design: system-level modeling/simulation/design, transistor-level integrated circuit design, microfabrication, and hardware-software integration.
Research Topics
Implantable in vivo dosimeter for cancer radiotherapy
Half of the cancer treatment utilizes radiation. The goal of the radiotherapy is to deliver a sufficient dose (energy deposition per mass by radiation) to tumors while minimizing the damage to organs at risk (OARs). The main mechanism of damaging the cancer cells by radiation is to break DNA structure to stop their proliferation. Keys to the successful treatment are 1) well-designed treatment planning, 2) monitoring the dose delivered to tumors and OARs, and 3) understanding true biological effect by radiation. In this plan, I would like to focus on the second goal by using the proposed in vivo dosimeter.
Integrated circuit (IC) based dosimetry is a whole new emerging field, and we especially developed a single charged particle dosimetry IC for the first time in the world. Most (or almost all) previous works measure only X-ray photons, limiting the application. The IC based dosimetry will be a game-changer and have a huge impact on cancer radiotherapy by significantly improving the treatment efficacy and safety. This project is a multidisciplinary work that spans integrated circuit and system design, nuclear physics, radiation oncology, radiology, and radiobiology.
Electronics often limit the overall size of the system. Especially, sensors and actuators require ultra small form factor so that lots of sensors can be deployed without affecting the system (i.e., human body). CMOS fabrication technology can address this issue by integrating billions of transistors in a millimeter-scale silicon chip. We are mainly focusing on designing a low-power millimeter-scale CMOS sensor IC, requiring solid understandings in wide topics in circuit design, including amplifier design, feedback analysis, frequency domain analysis, digital system design and synthesis, and full chip integration.
Li-ion Battery Management System
Electrified transportation requires real-time monitoring and controls for large-scale battery systems. This requires real-time feedback control for ensuring safety and performance. Especially, there have been enormous efforts in the area of modeling, estimation and controls for the battery management system (BMS).
Real-time hardware-in-the-loop (HIL) is essential for an advanced battery management system. The controller can set the battery current in real-time, which is especially critical for deep neural network (DNN) based algorithms. However, most conventional battery testers run open-loop, lacking real-time control. More importantly, the battery testers are bulky and expensive, precluding simultaneously testing many cells and BMS implementation in a product.
To address this issue, we demonstrated a hardware-software hardware prototype, enabling real-time accurate charging and discharging current monitoring and control. We are currently focusing on expanding the system using IC technology for testing lots of battery cells (>100).