Here you will be explained how to work with alpha layers. Goto your inventory. Choose the clothing you want. Go to the piece of clothing that says "Alpha Layer" on it. Right click it and choose for "add".
The alpha layer looks like this
<== You can reconize alpha layers by their checkered shirt icons
Now its time to put a mesh outfit on. Right click the mesh outfit and click "add".
If you wanna take it all off, you do the oppisite thing