Publications

54. Long–term kinetic profiling of legumain–activated fluorescent probes and identification of a legumain substrate for cleavable linker design

Ly Thi Nguyen, Quynh Le Nhat, Hyun Bo Sim, Julie Kang, Nhan Nguyen Thanh, Ny Thi Tuong Le, Jong-Jin Kim*, Dong-Jo Chang* 

Dyes and Pigments 2025, 113519, https://doi.org/10.1016/j.dyepig.2025.113519 

52. Therapeutic Effects of Cephalotaxus harringtonia Leaf Extract on Hepatocellular Carcinoma via Regulation of the Intrinsic Apoptosis Pathway and Cell Cycle 

Dae-Han Park, Sonny C Ramos, Hyun Bo Sim, Ju-Bin Lee, Ho-Yeol Jang, Beom-Gyun Jeong, Kyung-Wuk Park, Kyung-Yun Kang*, Jong-Jin Kim* 

Current Issues in Molecular Biology 2025, 47(12), 994; https://doi.org/10.3390/cimb47120994 

50. Activation of Lands Cycle-Mediated Inflammation in Living Macrophages Exposed to Label-Free Particulate Matter

Jeongwon Park, Jueun Lee, Hyun-Jin Kim, Su-Hyun Chae, JinO Shin, Jae-Hyuk Lee, Yeongmi Cheon, Youngae Jung, Seul-Ki Mun, Jong-Jin Kim, Sung-Hak Kim*, Geum-Sook Hwang*, Seongsoo Lee* 

Journal of Hazardous Materials 2025, 140027, https://doi.org/10.1016/j.jhazmat.2025.140027

48. Interpretation of the Transcriptome-Based Signature of Tumor-Initiating Cells, the Core of Cancer Development, and the Construction of a Machine Learning-Based Classifier

Seung-Hyun Jeong*, Jong-Jin Kim, Ji-Hun Jang, Young-Tae Chang* (Co-first)

Cells 2025, 14(16), 1255, https://doi.org/10.3390/cells14161255

46. Cellular metabolomics study in colorectal cancer cells and media following treatment with 5-fluorouracil by gas chromatography-tandem mass spectrometry

Songjin Oh, Hyun Bo Sim, Hyeongyeong Kim, Seul-Ki Mun, Moongi Ji, Byeongchan Choi, Doo-Young Kim, Jong-Jin Kim*, Man-Jeong Paik*

Metabolomics 2025, 21(62); https://doi.org/10.1007/s11306-025-02263-x 

44. Evaluation of Apoptosis-Inducing Coumarins Isolated from Peucedanum japonicum Roots: The Potential for Leukemia Treatment via the Mitochondria-Mediated Pathway

Kyung-Yun Kang, Sonny C Ramos, Sung-Ju Lee, Sang-Jip Nam*, Jong-Jin Kim*

Cells 2024, 13(23), 1982; https://doi.org/10.3390/cells13231982 

42. Promising Approach for Optimizing In Vivo Fluorescence Imaging in Tumor Mouse Model: Precision in Cancer Research 

Yu-Jeong Choi, Sonny C. Ramos, Hyun Bo Sim, Ji Yeon Han, Dae-Han Park, Seul-Ki Mun, Ju-Bin Lee, Chi-Ho Lee, Yong-An Lee*, and Jong-Jin Kim* 

Anticancer Research  2024, 44 (10) 4347-4358; DOI: https://doi.org/10.21873/anticanres.17264 

40. Development of Hsp90 Inhibitor to Regulate Cytokine Storms in Excessive Delayed- and Acute Inflammation

Hyun Bo Sim, Jun Sang Son, Sunil K. Gupta, Seung-Hyun Jeong, Yu-Jeong Choi, Ji Yeon Han, Sonny C. Ramos, Hyeongyeong Kim, Dae-Han Park, Ho Jin Yoo, Young Joo Yoo, Seul-Ki Mun*, Young Ho Seo*, Jong-Jin Kim*

International Immunopharmacology  2024, 137(2024) 112470; https://doi.org/10.1016/j.intimp.2024.112470 

38. Osseointegrative and immunomodulative 3D-Printing Ti6Al4V-based implants embedded with biogenic hydroxyapatite 

Sangbae Park, Juo Lee, Jong-Jin Kim, Moongi Ji, Eunbee Cho, Hyun Bo Sim, Young-Tae Chang, Jong Hoon Chung, Man-Jeong Paik, Jungsil Kim, Hoon Seonwoo (Co-first)

Materials & Design 2024, 240(2024), 112822; https://doi.org/10.1016/j.matdes.2024.112822 

36. Protopanaxadiol-Enriched Rice Exerted Antiadipogenic Activity during 3T3-L1 Differentiation and Anti-Inflammatory Activity in 3T3-L1 Adipocytes  

Chaiwat Monmai, Jin-Suk Kim, Hyun Bo Sim, Doh-Won Yun, Sung-Dug Oh, Eui-Shik Rha, Jong-Jin Kim*, So-Hyeon Baek*

Pharmaceutics 2023, 15(8), 2123; https://doi.org/10.3390/pharmaceutics15082123 

34. Visualizing inflammation with an M1 macrophage selective probe via GLUT1 as the gating target 

Heewon Cho, Haw-Young Kwon, Amit Sharma, Sun Hyeok Lee, Xiao Liu, Naoki Miyamoto, Jong-Jin Kim, Sin-Hyeog Im, Nam-Young Kang, Young-Tae Chang 

Nature communications  2022, 3, 5974 (2022). https://doi.org/10.1038/s41467-022-33526-z 

32. Anti-Inflammatory Effects of Phlebia sp. Extract in Lipopolysaccharide-Stimulated RAW 264.7 Macrophages

EH Lim, SK Mun, JJ Kim, DJ Chang, ST Yee

Biomed Research International 2022, 2022, 2717196, https://doi.org/10.1155/2022/2717196

30. Multimodal imaging probe development for pancreatic β cells: From fluorescence to PET

Nam-Young Kang, Jung Yeol Lee, Sang Hee Lee, In Ho Song, Yong Hwa Hwang, Min Jun Kim, Wut Hmone Phue, Bikram Keshari Agrawalla, Si Yan Diana Wan, Janise Lalic, Sung-Jin Park, Jong-Jin Kim, Haw-Young Kwon, So Hee Im, Myung Ae Bae, Jin Hee Ahn, Chang Siang Lim, Adrian Kee Keong Teo, Sunyou Park, Sang Eun Kim, Byung Chul Lee, Dong Yun Lee, Young-Tae Chang 

Journal of the American Chemical Society 2020, 142 (7), 3430-3439

28. Enhanced anti-tumor immunotherapy by dissolving microneedle patch loaded ovalbumin

Sung-Ju Lee, Hyeon-Seong Lee, Yun-Ho Hwang, Jong-Jin Kim, Kyung-Yun Kang, Seong Jin Kim, Hong Kee Kim, Jung Dong Kim, Do Hyeon Jeong, Man-Jeong Paik, Sung-Tae Yee 

PloS one 2019, 14 (8), e0220382

26. Development of a Universal Fluorescent Probe for Gram‐Positive Bacteria

Haw‐Young Kwon, Xiao Liu, Eun Gyeong Choi, Jung Yeol Lee, So‐Young Choi, Jun‐Young Kim, Lu Wang, Sung‐Jin Park, Beomsue Kim, Yong‐An Lee, Jong‐Jin Kim, Nam Young Kang, Young‐Tae Chang 

Angewandte Chemie International Edition 2019, 58 (25), 8426-8431

24. Imaging inflammation using an activated macrophage probe with Slc18b1 as the activation-selective gating target

Sung-Jin Park, Beomsue Kim, Sejong Choi, Sivaraman Balasubramaniam, Sung-Chan Lee, Jung Yeol Lee, Heon Seok Kim, Jun-Young Kim, Jong-Jin Kim, Yong-An Lee, Nam-Young Kang, Jin-Soo Kim, Young-Tae Chang 

Nature communications 2019, 10 (1), 1-7

22. Visualizing biofilm by targeting eDNA with long wavelength probe CDr15

Haw-Young Kwon, Jun-Young Kim, Xiao Liu, Jung Yeol Lee, Joey Kuok Hoong Yam, Louise Dahl Hultqvist, Wang Xu, Morten Rybtke, Tim Tolker-Nielsen, Wooseok Heo, Jong-Jin Kim, Nam-Young Kang, Taiha Joo, Liang Yang, Sung-Jin Park, Michael Givskov, Young-Tae Chang 

Biomaterials science 2019, 7 (9), 3594-3598

20. Identification of tumor initiating cells with a small‐molecule fluorescent probe by using vimentin as a biomarker

Yong‐An Lee, Jong‐Jin Kim, Jungyeol Lee, Jia Hui Jane Lee, Srikanta Sahu, Haw‐Young Kwon, Sung‐Jin Park, Se‐Young Jang, Jun‐Seok Lee, Zhenxun Wang, Wai Leong Tam, Bing Lim, Nam‐Young Kang, Young‐Tae Chang 

Angewandte Chemie International Edition 2018, 57 (11), 2851-2854 (Co-first)

18. Verification of the antioxidant activity of a subterranean part of Suaeda japonica Makino

KY Kang, YH Hwang, SJ Lee, JJ Kim, SJ Nam, ST Yee

Industrial Crops and Products 2017, 109, 836-842

14. Herbal preparation (HemoHIM) enhanced functional maturation of bone marrow-derived dendritic cells mediated toll-like receptor 4

Sung-Ju Lee, Jong-Jin Kim, Kyung-Yun Kang, Yun-Ho Hwang, Gil-Yeon Jeong, Sung-kee Jo, Uhee Jung, Hae-Ran Park, Sung-Tae Yee 

BMC complementary and alternative medicine 2016, 16 (1), 1-14

12. Antiosteoporosis activity of new oriental medicine preparation (Kyungokgo mixed with water extract of Hovenia dulcis) on the ovariectomized mice

Yun-Ho Hwang, Kwang-Jin Kim, Jong-Jin Kim, Kyung-Yun Kang, Sung-Ju Lee, Gil-Yeon Jeong, Kyung-Hee Choi, Young-Jin Son, Sung-Tae Yee 

Evidence-Based Complementary and Alternative Medicine 2015, 2015

10. Lichen secondary metabolites in Flavocetraria cucullata exhibit anti-cancer effects on human cancer cells through the induction of apoptosis and suppression of tumorigenic potentials

Thanh Thi Nguyen, Somy Yoon, Yi Yang, Ho-Bin Lee, Soonok Oh, Min-Hye Jeong, Jong-Jin Kim, Sung-Tae Yee, Florin Crişan, Cheol Moon, Kwang Youl Lee, Kyung Keun Kim, Jae-Seoun Hur, Hangun Kim 

PloS one 2014, 9 (10), e111575

8. Immunoadjuvant Efficacy of N-Carboxymethyl Chitosan for Vaccination via Dendritic Cell Activation

JJ Kim, JP Nam, JW Nah, MK Jang, ST Yee

Journal of medicinal food 2014, 17 (2), 268-277

6. Preventative effect of an herbal preparation (HemoHIM) on development of airway inflammation in mice via modulation of Th1/2 cells differentiation

JJ Kim, HW Cho, HR Park, U Jung, SK Jo, ST Yee

PLoS One 2013, 8 (7), e68552

4. Effect of Pueraria thunbergiana extracts on the activation of immune cells

JJ Kim, HJ Lee, ST Yee

Journal of Life Science 2012, 22 (8), 1107-1113

2. Ursolic acid ameliorates thymic atrophy and hyperglycemia in streptozotocin–nicotinamide-induced diabetic mice

J Lee, ST Yee, JJ Kim, MS Choi, EY Kwon, KI Seo, MK Lee

Chemico-Biological Interactions 2010, 188 (3), 635-642