The ability to use sound waves to manipulate micron sized objects solely based on their mechanical properties using a microfluidics platform is known as microscale acoustofluidics. In bulk acoustic devices, a standing wave is generated inside the microchannel using a piezoelectric transducer. A particle experiences acoustic radiation force due to the scattering of the incident wave when exposed to bulk acoustic wave (BAW). Understanding of the radiation forces can be exploited for the manipulation of micro objects and fluid interfaces.

Numerical simulations of fluid structure interaction phenomena at low Reynolds number are carried out using Finite sized Dissipative Particle Dynamics (FDPD). FDPD is a mesoscopic based simulation method which utilizes fluctuation dissipation theorem and hence proven to be advantageous for simulating biological object. We have developed new approaches to model boundary conditions in the case of complex geometry viz., constrictions, bifurcations, and sinusoidal. A low dimensional model of red blood cell (RBC) is developed. The dynamics of RBC in fluid flow inside a constricted microchannel is studied.