Publications

Significant Publications:

1. S. Maheshwari, Avula S Rao, Akhilesh Singh, L Ravithej Singh, Gopala R Palnati, Rakesh K Arya, Srikanth H Cheruvu, Sudhir Shahi, Tanuj Sharma, Sanjeev Meena, Anup K Singh, Ruchir Kant, Mohammed Riyazuddin, Himangsu K Bora, Mohammad I Siddiqi, Jiaur R Gayen, Koneni V. Sashidhara*, Dipak Datta*

Discovery of a novel small molecule inhibitor that targets PP2A-β-Catenin signaling and restricts tumor growth and metastasis.

Molecular Cancer Therapeutics. 2017, 16(9), 1791-1805.


CS-11 induces breast cancer cell–selective cytotoxic effects and promotes apoptosis.

2. Koneni V. Sashidhara*, Ranga Prasad Dodda, Akanksha Upadhyay, Gopala Reddy Palnati, Ram K. Modukuri, Ruchir Kant.

Synthesis of Highly Substituted Imidazo [1, 5‐a] quinoxalines Through a Multicomponent Reaction Followed by Deprotection–Cyclization.

Advanced Synthesis & Catalysis. 2016, 358, 2612-2618.


3. Koneni V. Sashidhara,*, K. Bhaskara Rao, Pragati Kushwaha, Ram K. Modukuri, Pratiksha Singh, Isha Soni, P. K. Shukla, Sidharth Chopra and Mukesh Pasupuleti.

Novel chalcone-thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus aureus.

ACS Medicinal Chemistry Letters. 2015, 6, 809-813. ((FRONT COVER PAGE) )


4. Koneni V. Sashidhara *, Gopala Reddy Palnati, L. Ravithej Singh, Amit Upadhyay, Srinivasa Rao Avula, Abdhesh Kumar and Ruchir Kant.

Molecular Iodine catalysed one-pot synthesis of chromeno[4,3-b] quinolin-6-ones under microwave irradiation.

Green Chemistry, 2015, 17, 3766-3770.


5. Koneni V. Sashidhara *, Ram K. Modukuri, Pooja Jadiya, Ranga Prasad Dodda , Manoj Kumar, Balasubramaniam Sridhar, Vikash Kumar, Rizwanul Haque, Mohammad Imran Siddiqi, Aamir Nazir. *

Benzofuran-Chalcone Hybrids as Potential Multifunctional Agents against Alzheimer’s Disease: Synthesis and in vivo Studies with Transgenic Caenorhabditis elegans

CHEMMEDCHEM, 9, 2014, 2671-2684


6. Koneni V. Sashidhara*, Ram K. Modukuri , Pooja Jadiya , K. Bhaskara Rao , Tanuj Sharma , Rizwanul Haque , Deependra Kumar Singh , Dibyendu Banerjee , Mohammad Imran Siddiqi, Aamir Nazir.

Discovery of 3-arylcoumarin-tetracyclic tacrine hybrids as multifunctional agents against Parkinson’s disease.

ACS Medicinal Chemistry Letters. 5, 2014, 1099-1103. (FRONT COVER PAGE).


7. Koneni V. Sashidhara*, Manoj Kumar, Vikram Khedgikar, Priyanka Kushwaha, Ram K. Modukuri, Abdhesh Kumar, Jyoti Gautam, Divya Singh, Balasubramaniam Sridhar, and Ritu Trivedi *.

Discovery of Coumarin-Dihydropyridine Hybrids as Bone Anabolic Agent.

Journal of Medicinal Chemistry, 56, 2013, 109-122.


8. Koneni V. Sashidhara*, Abdhesh Kumar, Shikha Agarwal, Manoj Kumar, Bikash Kumar, Balasubramanian Sridhar.

A Simple and Efficient Access to New Functionalized 4-phenacylideneflavenes.

Advanced Synthesis & Catalysis, 354, 2012, 1129-1140.


9. Koneni V. Sashidhara*, Manoj Kumar, Ravi Sonkar, Bhanu Shankar Singh, A. K. Khanna, Gitika Bhatia.

Indole-Based Fibrates as Potential Hypolipidemic and Antiobesity Agents. Journal of Medicinal Chemistry, 55, 2012, 2769-2779.


10. Pragya Misra, Koneni V Sashidhara*, Suriya P. Singh, Awanish Kumar, Reema Gupta, Shailendra S Chaudhaery, Souvik Sen Gupta, HK Majumder, Anil K Saxena, Anuradha Dube *

16α-hydroxycleroda-3, 13 (14) z-dien-15, 16-olide from polyalthia longifolia: A safe and orally active antileishmanial agent.

British Journal of Pharmacology, 159, 2010, 1143-1150.

List of all Publications:

100. Shrankhla Maheshwari, Avula S Rao, Akhilesh Singh, L Ravithej Singh, Gopala R Palnati, Rakesh K Arya, Srikanth H Cheruvu, Sudhir Shahi, Tanuj Sharma, Sanjeev Meena, Anup K Singh, Ruchir Kant, Mohammed Riyazuddin, Himangsu K Bora, Mohammad I Siddiqi, Jiaur R Gayen, Koneni V. Sashidhara*, Dipak Datta*

Discovery of a novel small molecule inhibitor that targets PP2A-β-Catenin signaling and restricts tumor growth and metastasis.

Molecular Cancer Therapeutics. 2017, 16(9), 1791-1805.

99. Sampa Gupta, Pooja Maurya, Akanksha Upadhyay, Pragati Kushwaha, Shagun Krishna, Mohammad Imran Siddiqi, Koneni V. Sashidhara*, Dibyendu Banerjee*

Synthesis and bio-evaluation of indole-chalcone based benzopyrans as promising antiligase and antiproliferative agents.

European Journal of Medicinal Chemistry. 2017, doi: 10.1016/j.ejmech.2017.11.015.

98. Ram K. Modukuri, Dharmendra Chodhary, Sampa Gupta, K Bhaskara Rao, Sulekha Adhikary, Tanuj Sharma, Mohammad Imran Siddiqi, Ritu Trivedi* and Koneni V. Sashidhara*

Benzofuran-dihydropyridine hybrids: A new class of potential bone anabolic agents.

Bioorganic & Medicinal Chemistry. 2017, 25, 6450-6466.

97. Suriya P. Singh and Koneni V. Sashidhara*

Lipid lowering agents of natural origin: An account of some promising chemotypes.

European Journal of Medicinal Chemistry. 2017, 140, 331-348.

96. L. Ravithej Singh, Srinivasa Rao Avula, Sneha Raj, Akanksha Srivastava, Gopala Reddy Palnati, Tripathi CKM, Mukesh Pasupuleti*, Koneni V. Sashidhara*

Coumarin-benzimidazole hybrids as a potent antimicrobial agent: synthesis and biological evaluation.

Journal of Antibiotics. 2017, 70(9), 954-961.

95. Dhanaraju Mandalapu, Bhavana Kushwaha, Sonal Gupta, Shagun Krishna, Nidhi Srivastava, Mahendra Shukla, Pratiksha Singh, Bhavana S Chauhan, Ravi Goyani, Jagdamba P Maikhuri, Koneni V Sashidhara, Brijesh Kumar, Renu Tripathi, Praveen K Shukla, Mohammad I Siddiqi, Gopal Gupta, Vishnu L Sharma*

Substituted carbamothioic amine-1-carbothioic thioanhydrides as novel trichomonicidal fungicides: Design, synthesis, and Biology.

European Journal of Medicinal Chemistry. 2017, doi.org/10.1016/j.ejmech.2017.11.060 (In press).

94. Raghib Ashraf,, Hamidullah,, Mohammad Hasanain,, Praveen Pandey, Mayank Maheshwari, L. Ravithej Singh, M. Quadir Siddiqui, Rituraj Konwar, Koneni V. Sashidhara , Jayanta Sarkar*.

Coumarin-chalcone hybrid instigates DNA damage by minor groove binding and stabilizes p53 through post translational modifications.

Scientific Reports. 2017, 7:45287.

93. Shiv Vardan Singh, Ashan Manhas, Suriya P Singh, Sonali Mishra, Nimisha Tiwari, Parmanand Kumar, Karuna Shanker, Kumkum Srivastava, Koneni V. Sashidhara, Anirban Pal.*

A phenolic glycoside from Flacourtia indica induces heme mediated oxidative stress in Plasmodium falciparum and attenuates malaria pathogenesis in mice.

Phytomedicine. 2017, 30, 1-9.

92. Shivangi Rastogi, Amit Kumar Singh, Gyan Chandra, Pragati Kushwaha , Garima Pant, Kavita Singh, Kalyan Mitra , Koneni V. Sashidhara , Manju Y. Krishnan.*

The diacylglycerol acyltransferase Rv3371 of Mycobacterium tuberculosis is required for growth arrest and involved in stress-induced cell wall alterations.

Tuberculosis. 2017, 104, 8-19.

91. Shivangi Rastogi, Amit Kumar Singh, Garima Pant, Kalyan Mitra, Koneni V. Sashidhara, Manju Y. Krishnan.*

Down-regulation of PE11, a cell wall associated esterase, enhances the biofilm growth of Mycobacterium tuberculosis and reduces cell wall virulence lipid levels.

Microbiology. 2017, 163, 52-61.

90. Koneni V. Sashidhara*, Ranga Prasad Dodda, Akanksha Upadhyay, Gopala Reddy Palnati, Ram K. Modukuri, Ruchir Kant.

Synthesis of Highly Substituted Imidazo [1, 5‐a] quinoxalines Through a Multicomponent Reaction Followed by Deprotection–Cyclization.

Advanced Synthesis & Catalysis. 2016, 358, 2612-2618.

89. Anil Kumar Jaiswal, K Bhaskara Rao, Pragati Kushwaha, Keerti Rawat, Ram K Modukuri, Prashant Khare, Sumit Joshi, Shikha Mishra, Ambak Rai, Koneni V Sashidhara*, Anuradha Dube.*

Development of Leishmania donovani stably expressing DsRed for flow cytometry-based drug screening using chalcone thiazolyl-hydrazone as a new antileishmanial target.

International Journal of Antimicrobial Agents. 2016, 48, 695-702.

88. Koneni V. Sashidhara,*, K. Bhaskara Rao, Ravi Sonkar, Ram K. Modukuri, Yashpal S Chhonker, Pragati Kushwaha, Hardik Chandasana, AK Khanna, Rabi S Bhatta, Gitika Bhatia, Manish Kumar Suthar, Jitendra Kumar Saxena, Vikash Kumar, Mohammad Imran Siddiqi.

Hybrids of coumarin–indole: design, synthesis and biological evaluation in Triton WR-1339 and high-fat diet induced hyperlipidemic rat models.

MedChemComm. 2016, 7, 1858-1869.

87. Koneni V. Sashidhara,*, L Ravithej Singh, Dharmendra Choudhary, Ashutosh Arun, Sampa Gupta, Sulekha Adhikary, Gopala Reddy Palnati, Rituraj Konwar, Ritu Trivedi.

Design, synthesis and in vitro evaluation of coumarin–imidazo [1, 2-a] pyridine derivatives against cancer induced osteoporosis.

RSC Advances. 2016, 6, 80037-80048.

86. Koneni V. Sashidhara,*, L Ravithej Singh, Gopala Reddy Palnati, Srinivasa Rao Avula, Ruchir Kant.

A Catalyst-Free One-Pot Protocol for the Construction of Substituted Isoindolinones under Sustainable Conditions.

SYNLETT. 2016, 27, 2384-2390.

85. Koneni V. Sashidhara,*, L Ravithej Singh, Mohammad Shameem, Sarika Shakya, Anoop Kumar, Tulsankar Sachin Laxman, Shagun Krishna, Mohammad Imran Siddiqi, Rabi S Bhatta, Dibyendu Banerjee*

Design, synthesis and anticancer activity of dihydropyrimidinone–semicarbazone hybrids as potential human DNA ligase 1 inhibitors

MedChemComm. 2016, 7, 2349-2363.

84. Alok Kumar Singh, Pratiksha Karaulia, Pragya Yadav, Tadigoppula Narender, Suriya P Singh, Koneni V. Sashidhara, Amit K Pandey, Sidharth Chopra, Arunava Dasgupta.*

Identification of lipid metabolism-targeting compounds active against drug-resistant M. tuberculosis.

Journal of Global Antimicrobial Resistance. 2016, 7, 26-27.

83. Koneni V. Sashidhara*, Srinivasa Rao Avula, Pawan Kumar Doharey, L. Ravithej Singh, Vishal M. Balaramnavar, Jyoti Gupta, Shailja Misra-Bhattacharya, Sushma Rathaur, Anil K. Saxena, Jitendra Kumar Saxena.*

Designing, synthesis of selective and high-affinity chalcone-benzothiazole hybrids as Brugia malayi thymidylate kinase inhibitors: in vitro validation and docking studies.

European Journal of Medicinal Chemistry. 2015, 103, 418-428.

82. Koneni V. Sashidhara,*, K. Bhaskara Rao, Pragati Kushwaha, Ram K. Modukuri, Pratiksha Singh, Isha Soni, P. K. Shukla, Sidharth Chopra and Mukesh Pasupuleti.

Novel chalcone-thiazole Hybrids as Potent Inhibitors of Drug Resistant Staphylococcus Aureus.

ACS Medicinal Chemistry Letters. 2015, 6, 809-813. (FRONT COVER PAGE)

81. Koneni V. Sashidhara *, Gopala Reddy Palnati, L. Ravithej Singh, Amit Upadhyay, Srinivasa Rao Avula, Abdhesh Kumar and Ruchir Kant

Molecular iodine catalysed one-pot synthesis of chromeno[4,3-b]quinolin-6-ones under microwave irradiation.

Green Chemistry. 2015, 17, 3766-3770.

80. Koneni V. Sashidhara *, Ram K. Modukuri , Seema Singh , K. Bhaskara Rao , G. Aruna Teja , Sampa Gupta , Shubha Shukla.

Design and synthesis of new series of coumarin-aminopyran derivatives possessing potential anti-depressant-like activity.

Bioorganic & Medicinal Chemistry Letters. 2015, 25, 337-341.

79. Muheeb Beg, Kripa Shankar, Salil Varshney, Sujith Rajan, Suriya Pratap Singh, Pankaj Jagdale, Anju Puri, Bhushan P. Chaudhari, Koneni V. Sashidhara*, Anil Nilkanth Gaikwad.*

A clerodane diterpene inhibit adipogenesis by cell cycle arrest and ameliorate obesity in C57BL/6 mice.

Molecular and Cellular Endocrinology. 2015, 399, 373-385.

78. Koneni V. Sashidhara*, Srinivasa Rao Avula, Vaibhav Mishra, Gopal Reddy Palnati, L. Ravithej Singh, Neetu Singh, Yashpal S. Chhonker, Priyanka Swami, R.S. Bhatta, Gautam Palit.

Identification of quinoline-chalcone hybrids as potential antiulcer agents.

European Journal of Medicinal Chemistry. 2015, 89, 638-653.

77. Koneni V. Sashidhara *, Ram K. Modukuri, Pooja Jadiya, Ranga Prasad Dodda , Manoj Kumar, Balasubramaniam Sridhar, Vikash Kumar, Rizwanul Haque, Mohammad Imran Siddiqi, Aamir Nazir. *

Benzofuran--Chalcone Hybrids as Potential Multifunctional Agents against Alzheimer’s Disease: Synthesis and in vivo Studies with Transgenic Caenorhabditis elegans

CHEMMEDCHEM. 2014, 9, 2671-2684.

76. Koneni V. Sashidhara*, Ram K. Modukuri , Pooja Jadiya , K. Bhaskara Rao , Tanuj Sharma , Rizwanul Haque , Deependra Kumar Singh , Dibyendu Banerjee , Mohammad Imran Siddiqi, Aamir Nazir.

Discovery of 3-arylcoumarin-tetracyclic tacrine hybrids as multifunctional agents against Parkinson’s disease.

ACS Medicinal Chemistry Letters. 2014, 5, 1099-1103. (FRONT COVER PAGE).

75. Koneni V. Sashidhara *, Suriya P. Singh, Salil Varshney, Muheeb Beg, Anil N. Gaikwad.

Poliothrysoside and its derivatives as novel insulin sensitizers potentially driving AMPK activation and inhibiting adipogenesis.

European Journal of Medicinal Chemistry. 2014, 86, 570-577.

74. Koneni V. Sashidhara *, K. Bhaskara Rao, Seema Singh, Ram K. Modukuri, G. Aruna Teja, Hardik Chandasana, Shubha Shukla, Rabi S. Bhatta.

Synthesis and evaluation of new 3-phenylcoumarin derivatives as potential antidepressant agents.

Bioorganic & Medicinal Chemistry Letters. 2014, 24, 4876-4880.

73. Manoj Kathuria , Arindam Bhattacharjee , Koneni V. Sashidhara, Suriya Pratap Singh, Kalyan Mitra *.

Induction of mitochondrial dysfunction and oxidative stress in Leishmania donovani by orally active clerodane diterpene.

Antimicrobial Agents & Chemotherapy. 2014, 58, 5916-5928.

72. Koneni V. Sashidhara *, K. Bhaskara Rao, Vikas Kushwaha, Ram K. Modukuri, Richa Verma, P.K. Murthy.*

Synthesis and antifilarial activity of chalcone-thiazole derivatives against a human lymphatic filarial parasite, Brugia malayi.

European Journal of Medicinal Chemistry. 2014, 81, 473-480.

71. Koneni V. Sashidhara *, Ranga Prasad Dodda, Ravi Sonkar, Gopala Reddy Palnati, Gitika Bhatia.

Design and synthesis of novel indole-chalcone fibrates as lipid lowering agents.

European Journal of Medicinal Chemistry. 2014, 81, 499-509.

70. Neetu Singh, Jayanta Sarkar*, Koneni V. Sashidhara, Shakir Ali, Sudhir Sinha.*

Anti-tumor activity of a novel coumarin-chalcone hybrid is mediated through intrinsic apoptotic pathway by inducing PUMA and altering Bax/Bcl-2 ratio.

Apoptosis. 2014, 19, 1017-1028.

69. Koneni V. Sashidhara * , Ram K. Modukuri, Dharmendra Choudhary, K. Bhaskara Rao, Manoj Kumar, Vikram Khedgikar, Ritu Trivedi.

Synthesis and evaluation of new coumarin-pyridine hybrids with promising anti- osteoporotic activities.

European Journal of Medicinal Chemistry. 2013, 70, 802-810.

68. Koneni V. Sashidhara *, Ram K. Modukuri, Ravi Sonkar, K. Bhaskara Rao, Gitika Bhatia.

Hybrid benzofuran–bisindole derivatives: New prototypes with promising anti- hyperlipidemic activities.

European Journal of Medicinal Chemistry. 2013, 68, 38-46.

67. Koneni V. Sashidhara *, Gopala Reddy Palnati, Ranga Prasad Dodda, Srinivasa Rao Avula, Priyanka Swami.

One Pot Regioselective Synthesis of Imidazole and 2,3-Dihydroquinazolinone Derivatives- An easy access to Nature Like Molecules.

SYNLETT. 2013, 24, 1795-1800.

66. Koneni V. Sashidhara *, Gopala Reddy Palnati, Ravi Sonkar, Srinivasa Rao Avula, Chetan Awasthi, Gitika Bhatia.

Coumarin chalcone fibrates: A new structural class of lipid lowering agents. European Journal of Medicinal Chemistry. 2013, 64, 422-431.

65. Shakti Deep Pachauri, Kiran Khandelwal, Suriya P. Singh, Koneni V. Sashidhara, Anil Kumar Dwivedi *.

HPLC method for identification and quantification of two potential anti-inflammatory and analgesic agents-1,3-dibenzyl urea and aurantiamide acetate in the roots of Moringa oleifera.

Medicinal Chemistry Research. 2013, 11, 5284-5289.

64. Koneni V. Sashidhara*, Manoj Kumar, Vikram Khedgikar, Priyanka Kushwaha, Ram K. Modukuri, Abdhesh Kumar, Jyoti Gautam, Divya Singh, Balasubramaniam Sridhar, and Ritu Trivedi *.

Discovery of Coumarin-Dihydropyridine Hybrids as Bone Anabolic Agent.

Journal of Medicinal Chemistry. 2013, 56, 109-122.

63. Koneni V. Sashidhara*, Srinivasa Rao Avula, Komal Sharma, Gopala Reddy Palnati, Surendar Reddy Bathul *.

Discovery of coumarin-monastrol hybrid as potential antibreast tumor-specific agent.

European Journal of Medicinal Chemistry. 2013, 60, 120-127.

62. Koneni V. Sashidhara*, Suriya P. Singh, Shiv Vardan Singh, Rajeev K. Srivastava, Kumkum Srivastava, J.K. Saxena, Sunil K. Puri.

Isolation and identification of β-hematin inhibitors from Flacourtia indica as promising antiplasmodial agents.

European Journal of Medicinal Chemistry. 2013, 60, 497-502.

61. Koneni V. Sashidhara*, Gopala Reddy Palnati, Ranga Prasad Dodda, Srinivasa Rao Avula, Priyanka Swami.

Studies on Novel Synthetic Methodologies, Part XII: An Efficient One-Pot Access to 6,6a-Dihydroisoindolo[2,1-a]quinazoline-5,11-diones and 5-Phenylisoindolo[2,1-a]quinazolin-11(6aH)-ones.

SYNLETT. 2013, 24, 105-113.

60. Koneni V. Sashidhara*, Suriya P. Singh , Anuj Srivastava, Anju Puri.

Main extracts and hypolipidemic effects of the Bauhinia racemosa Lam. leaf extract in HFD-fed hamsters.

Natural Product Research. 2013, 27, 1127-1131.

59. Koneni V. Sashidhara*, Abdhesh Kumar, Ranga Prasad Dodda, Bikash Kumar.

A new iodine catalyzed regioselective synthesis of xanthene synthons.

Tetrahedron Letters. 2012, 53, 3281-3283.

58. Koneni V. Sashidhara*, Manoj Kumar, Abdhesh Kumar.

A novel route to synthesis of flavones from salicylaldehyde and acetophenone derivatives.

Tetrahedron Letters. 2012, 53, 2355-2359.

57. Koneni V. Sashidhara*, Abdhesh Kumar, Shikha Agarwal, Manoj Kumar, Bikash Kumar,

Balasubramanian Sridhar.

A Simple and Efficient Access to New Functionalized 4-phenacylideneflavenes.

Advanced Synthesis & Catalysis. 2012, 354, 1129-1140.

56. Koneni V. Sashidhara*, Manoj Kumar, Ram K. Modukuri, Rajeev Kumar Srivastava, Awakash Soni, Kumkum Srivastava, Shiv Vardan Singh, J.K. Saxena, Harsh M. Gauniyal, Sunil K. Puri.

Antiplasmodial activity of novel keto-enamine chalcone-chloroquine based hybrid pharmacophores.

Bioorganic & Medicinal Chemistry. 2012, 20, 2971-2981.

55. Koneni V. Sashidhara*, Abdhesh Kumar, Ranga Prasad Dodda, Naikade Niraj Krishna, Pooja Agarwal, Kumkum Srivastava, S.K. Puri.

Coumarin-trioxane hybrids: Synthesis and evaluation as a new class of antimalarial scaffolds.

Bioorganic & Medicinal Chemistry Letters. 2012, 22, 3926-3930.

54. Koneni V. Sashidhara*, Gopala Reddy Palnati, Ranga Prasad Dodda, Ravi Sonkar, A.K. Khanna, Gitika Bhati.

Discovery of amide based fibrates as possible antidyslipidemic and antioxidant agents.

European Journal of Medicinal Chemistry. 2012, 57, 302-310.

53. Koneni V. Sashidhara*, Gopala Reddy Palnati, Srinivasa Rao Avula, Abdhesh Kumar.

Efficient and general synthesis of 3-aryl coumarins using cyanuric chloride.

SYNLETT. 2012, 23, 611-621.

52. Koneni V. Sashidhara*, Suriya P. Singh, Sweta Misra, Jyoti Gupta, Shailja Misra-Bhattacharya.

Galactolipids from Bauhinia racemosa as a new class of antifilarial agents against human lymphatic filarial parasite, Brugia malayi.

European Journal of Medicinal Chemistry. 2012, 50, 230-235.

51. Koneni V. Sashidhara*, Abdhesh Kumar, K. Bhaskara Rao, Vikas Kushwaha, Kirti Saxena, P.K. Murthy.

In vitro and in vivo antifilarial activity evaluation of 3, 6-epoxy[1,5]dioxocines: A new class of antifilarial agents.

Bioorganic & Medicinal Chemistry Letters. 2012, 22, 1527-1532.

50. Koneni V. Sashidhara*, Manoj Kumar, Ravi Sonkar, Bhanu Shankar Singh, A. K. Khanna, Gitika Bhatia.

Indole-Based Fibrates as Potential Hypolipidemic and Antiobesity Agents.

Journal of Medicinal Chemistry. 2012, 55, 2769-2779.

49. Koneni V. Sashidhara*, Srinivasa Rao Avula, L. Ravithej Singh, Gopala Reddy Palnati.

A facile and efficient Bi(III) catalyzed synthesis of 1,1-dihydroperoxides and 1,2,4,5-tetraoxanes.

Tetrahedron Letters. 2012, 53, 4880-4884.

48. R. S. Bhatta*, Devendra Kumar, Y. S. Chhonker, Deepak Kumar, Suriya P. Singh, Koneni V. Sashidhara, G. K. Jain.

Simultaneous estimation of 16α-hydroxycleroda-3, 13(14) Z-dien-15, 16-olide from Polyalthia longifolia and its metabolite in hamster plasma: application to pharmacokinetic study.

Biomedical Chromatography. 2012, 26, 559-565.

47. Koneni V. Sashidhara*, Gopala Reddy Palnati, Srinivasa Rao Avula, Surendra Singh, Manish Jain, Madhu Dikshit.

Synthesis and evaluation of anti-thrombotic activity of benzocoumarin amide derivatives.

Bioorganic & Medicinal Chemistry Letters. 2012, 22, 3115-3121.

46. Koneni V. Sashidhara*, Srinivasa Rao Avula, Gopala Reddy Palnati, Shiv Vardan Singh, Kumkum Srivastava, Sunil K. Puri, J.K. Saxena.

Synthesis and in vitro evaluation of new chloroquine-chalcone hybrids against chloroquine-resistant strain of Plasmodium falciparum.

Bioorganic & Medicinal Chemistry Letters. 2012, 22, 5455-5459.

45. Koneni V. Sashidhara*, Manoj Kumar, Ram K. Modukuri, Anuj Srivastava, Anju Puri.

Discovery and synthesis of novel substituted benzocoumarins as orally active lipid modulating agents.

Bioorganic & Medicinal Chemistry Letters. 2011, 21, 6709-6713.

44. Koneni V. Sashidhara*, Suriya P. Singh, Anuj Srivastava, Anju Puri, Yashpal S. Chhonker, Rabi S. Bhatta, Priyanka Shah, Mohammad Imran Siddiqi.

Discovery of a new class of HMG-CoA reductase inhibitor from Polyalthia longifolia as potential lipid lowering agent.

European Journal of Medicinal Chemistry. 2011, 46, 5206-5211.

43. Koneni V. Sashidhara*, Suriya P. Singh , Anuj Srivastava, Anju Puri.

Identification of the antioxidant principles of Polyalthia longifolia var. pendula using TEAC assay.

Natural Product Research. 2011, 25, 918-926.

42. Koneni V. Sashidhara*, Manoj Kumar, Ram K. Modukuri, Ravi Sonkar, Gitika Bhatia, A.K. Khanna, Shivika Rai, Rakesh Shukla.

Synthesis and anti-inflammatory activity of novel biscoumarin-chalcone hybrids.

Bioorganic & Medicinal Chemistry Letters. 2011, 21, 4480-4484.

41. Koneni V. Sashidhara*, Abdhesh Kumar, K. Bhaskara Rao.

Synthesis of 3, 6-epoxy [1, 5] dioxocines from 2-hydroxyaromatic benzaldehydes.

Tetrahedron Letters. 2011, 52, 5659-5663.

40. Koneni V. Sashidhara*, Abdhesh Kumar, Manoj Kumar, S. Singh, Manish Jain, Madhu Dikshit.

Synthesis of novel 3-carboxamide-benzocoumarin derivatives as orally active antithrombotic agents.

Bioorganic & Medicinal Chemistry Letters, 2011, 21, 7034-7040.

39. Koneni V. Sashidhara*, Manoj Kumar, Ram K. Modukuri, Anuj Srivastava, Anju Puri.

Discovery and synthesis of novel 3-phenylcoumarin derivatives as antidepressant agents

Bioorganic & Medicinal Chemistry Letters. 2011, 21, 1937-1941.

38. Koneni V. Sashidhara*, Abdhesh Kumar, Manoj Kumar, Jayanta Sarkar, Sudhir Sinha.

Synthesis and in vitro evaluation of novel coumarin-chalcone hybrids as potential anticancer agents.

Bioorganic & Medicinal Chemistry Letters. 2010, 20, 7205-7211.

37. Koneni V. Sashidhara*, Jammikuntla N. Rosaiah, Manoj Kumar, Rishi Kumar Gara, Lakshma Vadithe Nayak, Kamini Srivastava, Hemant Kumar Bid, Rituraj Konwar.

Neo-tanshinlactone inspired synthesis, in vitro evaluation of novel substituted benzocoumarin derivatives as potent anti-breast cancer agents.

Bioorganic & Medicinal Chemistry Letters. 2010, 20, 7127-7131.

36. Koneni V. Sashidhara*, Abdhesh Kumar, Manoj Kumar, Anuj Srivastava, Anju Puri.

Synthesis and antihyperlipidemic activity of novel coumarin bisindole derivatives.

Bioorganic & Medicinal Chemistry Letters. 2010, 20, 6504-6507.

35. Koneni V. Sashidhara*, Suriya P. Singh, Ruchir Kant, Prakas R. Maulik, Jayanta Sarkar, Sanjeev Kanojiya, K. Ravi Kumar.

Cytotoxic cycloartane triterpene and rare isomeric bisclerodane diterpenes from the leaves of Polyalthia longifolia var. pendula.

Bioorganic & Medicinal Chemistry Letters. 2010, 20, 5767-5771.

34. Ram Swaroop Verma*, Koneni V. Sashidhara, Anju Yadav.

Essential oil composition of 'blue flower rosemary' (Rosmarinus officinalis L.) from subtropical India.

Acta Pharmaceutica Sciencia. 2010, 52, 427-430.

33. Ram Swaroop Verma*, Koneni V. Sashidhara, Anju Yadav, A.A. Naqvi.

Essential oil composition of Majorana hortensis (Moench) from subtropical India.

Acta Pharmaceutica Sciencia. 2010, 52, 19-22.

32. Koneni V. Sashidhara*, Abdhesh Kumar, Manoj Kumar, Ravi Sonkar, Gitika Bhatia, A.K. Khanna.

Novel coumarin derivatives as potential antidyslipidemic agents.

Bioorganic & Medicinal Chemistry Letters. 2010, 20, 4248-4251.

31. J. Brian Morgan, Fakhri Mahdi, Yang Liu, Veena Coothankandaswamy, Mika B. Jekabsons, Tyler A. Johnson, Koneni V. Sashidhara, Phillip Crews, Dale G. Nagle*, Yu-Dong Zhou*.

The marine sponge metabolite mycothiazole: a novel prototype mitochondrial complex I inhibitor.

Bioorganic & Medicinal Chemistry. 2010, 18, 5988-5994.

30. Koneni V. Sashidhara*, Jammikuntla N. Rosaiah, Abdhesh Kumar, Gitika Bhatia, A.K. Khanna.

Synthesis of novel benzocoumarin derivatives as lipid lowering agents.

Bioorganic & Medicinal Chemistry Letters. 2010, 20, 3065-3069.

29. Koneni V. Sashidhara *, Jammikuntla N. Rosaiah, Abdhesh Kumar.

Unusual reaction of 6-formyl-2-ox-2H-benzo[h]chromene-3-carboxylic acid ethyl ester with aliphatic amines.

Synthetic Communications. 2010, 1, 21-28.

28. Tyler A. Johnson, Micaela V. C. Morgan, Natalie A. Aratow, Samarkand A. Estee, Koneni V. Sashidhara, Steven T. Loveridge, Nathaniel L. Segraves, Phillip Crews *.

Assessing pressurized liquid extraction for the high-throughput extraction of marine-sponge-derived natural products.

Journal of Natural Products. 2010, 73, 359-364.

27. Pragya Misra, Koneni V Sashidhara*, Suriya P. Singh, Awanish Kumar, Reema Gupta, Shailendra S Chaudhaery, Souvik Sen Gupta, HK Majumder, Anil K Saxena, Anuradha Dube *.

16α-hydroxycleroda-3, 13 (14) z-dien-15, 16-olide from polyalthia longifolia: A safe and orally active antileishmanial agent.

British Journal of Pharmacology. 2010, 159, 1143-1150.

26. Koneni V. Sashidhara*, Suriya P. Singh , Jayanta Sarkar, Sudhir Sinha.

Cytotoxic clerodane diterpenoids from the leaves of Polyalthia longifolia.

Natural Product Research. 2010, 24, 1687-1694.

25. Koneni V. Sashidhara, Kimberly N. White and Phillip Crews *.

A selective account of effective paradigms and significant outcomes in the discovery of inspirational marine natural products.

Journal of Natural Products. 2009, 72, 588-603.

24. Koneni V. Sashidhara*, Suriya P. Singh, P.K. Shukla.

Antimicrobial evaluation of clerodane diterpenes from Polyalthia longifolia var. pendula.

Natural Product Communications. 2009, 4, 327-330.

23. Koneni V. Sashidhara*, Abdhesh Kumar, Gitika Bhatia, M.M. Khan, A.K. Khanna, J.K. Saxena.

Antidyslipidemic and antioxidative activities of 8-hydroxyquinoline derived novel keto-enamine Schiffs bases.

European Journal of Medicinal Chemistry. 2009, 44, 1813-1818.

22. Koneni V. Sashidhara*, Jammikuntla N. Rosaiah, Ethika Tyagi, Rakesh Shukla, Ram Raghubir, Siron M. Rajendran.

Rare dipeptide and urea derivatives from roots of Moringa oleifera as potential anti-inflammatory and antinociceptive agents.

European Journal of Medicinal Chemistry. 2009, 44, 432-436.

21. Tyler A. Johnson, Taro Amagata, Koneni V. Sashidhara, Allen G. Oliver, Karen Tenney, Teatulohi Matainaho, Kenny Kean-Hooi Ang, James H. McKerrow, Phillip Crews *.

The aignopsanes, a new class of sesquiterpenes from selected chemotypes of the sponge Cacospongia mycofijiensis.

Organic Letters. 2009, 11, 1975-1978.

20. Koneni V. Sashidhara*, Jammikuntla N. Rosaiah, Abdhesh Kumar.

Iodine catalyzed mild and efficient method for the synthesis of chalcones.

Synthetic Communications. 2009, 39, 2288-2296.

19. Koneni V. Sashidhara* , Jammikuntla N. Rosaiah, Abdhesh Kumar.

New protocol for masking and unmasking vicinal hydroxyl and formyl groups in6-hydroxyarene-1,3-dicarboxaldehydes.

Synthetic Communications. 2009, 39, 1809-1816.

18. Koneni V. Sashidhara*, Jammikuntla N. Rosaiah, Gitika Bhatia, J.K. Saxena.

Novel keto-enamine Schiffs bases from 7-hydroxy-4-methyl-2-oxo-2H-benzo[h] chromene-8,10-dicarbaldehyde as potential antidyslipidemic and antioxidant agents.

European Journal of Medicinal Chemistry. 2008, 43, 2592-2596.

17. Koneni V. Sashidhara*, Jammikuntla N. Rosaiah , Tadigoppula Narender *.

Highly efficient and regioselective synthesis of keto-enamine Schiff bases of 7-Hydroxy-4-methyl-2-oxo-2H-benzo[h]chromene-8,10-dicarbaldehyde and 1-Hydroxynaphthalene-2,4-dicarbaldehyde.

Tetrahedron Letters. 2007, 48, 1699-1702.

16. Pratibha Khare, K. V. Sashidhara, Anju Yadav*, S. N. Garg, S. P. S. Khanuja.

Chemical composition of the inflorescence essential oil of Coleus forskohlii.

Indian Perfumer. 2007, 51, 47-48.

15. Karuna Shanker, Arvind S. Negi, Sunil K. Chattopadhyay*, K. V. Sashidhara, Tanpreet Kaur, M.L. Gupta, P. Agrawal, A. Misra.

Determination of paclitaxel, 10-DAB, and related taxoids in Himalayan yew using reverse phase HPLC.

Journal of Herbs, Spices & Medicinal Plants. 2007, 13, 25-44.

14. Koneni V. Sashidhara*, Jammikuntla N. Rosaiah

Vicarious nucleophilic substitution in enamine derivatives of 1-hydroxynaphthalene-2,4-dicarbaldehyde.

Tetrahedron Letters. 2007, 48, 3285-3287.

13. Koneni V. Sashidhara*, Jammikuntla N. Rosaiah, Abdhesh Kumar, Hemant K Bid, Rituraj Konwar, Naibedya Chattopadhyay.

Cell growth inhibitory action of an unusual labdane diterpene, 13-epi-sclareol in breast and uterine cancers in vitro.

Phytotherapy Research. 2007, 21, 1105-1108.

12. Koneni V. Sashidhara*, Jammikuntla N. Rosaiah

Various dereplication strategies using LC-MS for rapid natural product lead identification and drug discovery.

Natural Product Communications. 2007, 2, 193-202.

11. H. P. Kaur , S. N. Garg* , K. V. Sashidhara , A. Yadav , A. A. Naqvi, S. P.S. Khanuja.

Chemical composition of the essential oil of the twigs and leaves of Aegle marmelos (L.) Correa.

Journal of Essential Oil Research. 2006, 18, 288-289.

10. K. V. Sashidhara*, R. S. Verma, P. Ram.

Essential oil composition of Matricaria recutita L. from the lower region of the Himalayas.

Flavour and Fragrance Journal. 2006, 21, 274-276.

9. K. V. Sashidhara *, R. S. Verma, P. Ram.

Constituents of leaf essential oil of Amomum subulatum Roxb. from lower region of Himalayas.

Indian Perfumer. 2005, 49, 169-171.

8. Sunil K. Chattopadhyay*, Sachin Srivastava, Koneni V. Sashidhara, Arun K. Tripathi, Asish K. Bhattacharya, Arvind S. Negi.

Betuligenol derivative with growth inhibition and antifeedant activity.

Bioorganic & Medicinal Chemistry Letters. 2004, 14, 1729-1731.

7. K. V. Sashidhara*, R. S. Verma, P. Ram.

Evaluation of geranium cultivars (Pelargonium graveolens) in Tarai region of Uttaranchal.

Indian Perfumer. 2004, 48, 273-276.

6. S. N. Garg*, Deepti Gupta, K. V. Sashidhara, V. K. Mehta.

Alpinia galanga L.- Composition of essential oil from flowers.

Indian Perfumer. 2003, 47, 147-149.

5. K. P. Madhusudanan*, S. K. Chattopadhyay, V. K. Tripathi, K. V. Sashidhara, A. K. Kukreja, S. P. Jain.

LC-ESI-MS analysis of taxoids from the bark of Taxus wallichiana.

Biomedical Chromatography. 2002, 16, 343-355.

4. K. P. Madhusudanan*, S. K. Chattopadhyay, V. Tripathi, K. V. Sashidhara, S. Kumar.

MS/MS profiling of taxoids from the needles of Taxus wallichiana.

Phytochemical Analysis. 2002, 13, 18-30.

3. S. K. Chattopadhyay*, V. Tripathi, K. V. Sashidhara, V. K. Mehta, B.S. Joshi, R. Roy

Studies on the Himalayan yew Taxus wallichiana: part IX-the chemical constituents of the seeds of Taxus wallichiana.

Indian Journal of Chemistry, Section B. 2002, 41B, 225-227.

2. S. K. Chattopadhyay*, M. Kulshrestha, V. Tripathi, K. V. Sashidhara, S. Kumar.

Important phenolic constituents of the Himalayan Yew Taxus wallichiana.

Journal of Medicinal and Aromatic Plant Sciences. 2000, 22, 710-714.

1. Shashi Bala, G.C Uniyal*, S.K Chattopadhyay, V Tripathi, K. V. Sashidhara, M Kulshrestha, R.P Sharma, S.P Jain, A.K Kukreja, S Kumar.

Analysis of taxol and major taxoids in Himalayan yew, Taxus wallichiana.

Journal of Chromatography, A. 1999, 858, 239-244.