Aptamer Pattern Recognition in using SELEX data

SELEX Data Generation

Systematic Evolution of Ligands by EXponential Enrichment (SELEX) is a common method currently used for isolating high-affinity single-stranded (ss) DNAs or RNAs from a large library with random sequences

Aptamers

Aptamers are single-stranded oligonucleotides that fold into defined architectures and bind to targets such as proteins

Project TimeLine

Found the human embryonic stem cells whole-cell SELEX-Seq data
Download Data and import it in python
Generate Sequence Profiles based on the counts
Compare the Control and Original data
Find Aptamer candidates
Find the Aptamer pattern based on the candidates
compare with the paper results

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