DAY 1: JULY 23, 2019
8:20-8:30AM Welcome and opening remarks: James Monaghan, Northeastern University
8:30-9:15AM Perspectives Speaker: Karen Crawford, Professor, St. Mary’s College of Maryland. From axolotl regeneration to cephalopod development: incorporating undergrads into your research program.
SESSION 1: DEVELOPMENT AND REGENERATION
9:15-10:00AM Invited Speaker: Randal Voss, Professor, U. Kentucky Medical School. Discovery and Validation of Chemical Genetic Tools for Regenerative Biology.
10:00-10:15AM - Melissa Keinath, Carnegie Institution for Science. Fluorescent in situ hybridization of BAC clones on axolotl lampbrush chromosomes reveals the molecular organization of the transcription loops.
10:15-10:30AM - David Shook, University of Virginia, School of Medicine. Epithelial-mesenchymal transition both internalizes mesoderm through a bi-lateral primitive streak and generates forces that drive gastrulation movements.
10:30-11:00AM Coffee Break
SESSION 2: GENOMICS
11:00-11:45AM Invited Speaker: Sergej Nowoshilow, Research Institute for Molecular Pathology, Vienna. Putting together the puzzle - assembly and annotation of the axolotl genome
11:45-12:00AM - María Torres-Sánchez, University of Kentucky. Protein-coding genetic variation in the Mexican axolotl.
12:00-12:15AM - Wouter Masselink, Research Institute for Molecular Pathology, Vienna. Segmentation of the regenerating axolotl tail.
12:15–1:45PM Lunch Break and trainee fellowship workshop
SESSION 3: ORGAN DEVELOPMENT AND REGENERATION
1:45-2:30PM Invited Speaker: Katia Del Rio Tsonis, Professor, Miami University. Models for eye tissue regeneration.
2:30-2:45PM - Anastasia Polikarpova, Research Institute for Molecular Pathology, Vienna. Skin and muscle connective tissue cells in axolotl bone healing.
2:45-3:00PM - Stephanie Tsai, Harvard University. Midkine regulates wound epidermis function and development in limb regeneration.
3:00-3:15PM - Akira Satoh, Okayama University. Conserved regeneration mechanism regulates axolotl tooth, tail, gill, and limb regeneration.
3:15-3:45PM - Coffee Break
SESSION 4: LIMB DEVELOPMENT AND REGENERATION
3:45-4:30PM Invited Speaker: Kate McCusker, Assistant Professor, University of Massachusetts at Boston. The role of cell plasticity during pattern formation in the axolotl limb regenerate.
4:30-4:45PM - Konstantinos Sousounis, Harvard University. DNA damage and the role of Eya2 during axolotl limb regeneration.
4:45-5:00PM - Stéphane Roy, Universté de Montréal. Axolotl limb regeneration: TGF-beta to start and BMP to finish.
SESSION 5: MUSCLE AND CONNECTIVE TISSUE REGENERATION (AND LIMB)
5:00-5:45PM Invited Speaker: Tatiana Sandoval-Guzmán, Group leader, University of Dresden. Elucidating the role of connective tissue cells in complex tissue regeneration.
DAY 2: JULY 24, 2019
SESSION 1: TRANSGENIC TECHNOLOGIES
8:30-9:15AM Invited Speaker: Ji-feng Fei, South China Normal University. Axolotl, an ideal model for dissecting the mystery of spinal cord regeneration.
9:15-9:30AM - G Parker Flowers, Yale University. Identifying essential regeneration genes in chimeric haploid axolotl limbs.
9:30-9:45AM - Timothy Duerr, Northeastern University. Visualization and functional analysis of RA responsive genes in the axolotl.
9:45-10:15 Coffee Break
SESSION 2: NERVOUS SYSTEM DEVELOPMENT AND REGENERATION
10:15-11:00AM Invited Speaker: Alberto Joven, Karolinska Institute. Brain regeneration in the Spanish Ribbed Newt.
11:00-11:15AM - Keith Sabin, Marine Biological Laboratory. AP-1cFos/JunB/miR-200a regulate the pro-regenerative glial cell response during axolotl spinal cord regeneration
11:15-11:30AM - Robert Carlone, Brock University. Endocannabinoid signaling and spinal cord regeneration in Ambystoma mexicanum.
11:30AM - 2:00PM Lunch Break and Poster Session
Session 3: DISEASE MODELS
2:00-2:45PM Invited Speaker: Maximina Yun, Group leader, University of Dresden. The role of senescence in regeneration in newts and axolotls.
2:45-3:00PM - George Tsissios, Miami University. Regulating lens regenerative potential through Eph receptor signaling.
3:00-3:15PM - Olena Zhulyn, Stanford University. Rapid remodeling of the translatome underlies wound closure and regeneration.
SESSION 4: CONSERVATION OF MECHANISMS ACROSS ANIMALS
3:15-4:00PM Invited Speaker: Ryan Kerney, Associate Professor, Gettysburg College. Developing with microbes – algal endosymbiosis in the spotted salamander (Ambystoma maculatum).
4:00-4:45PM Invited Speaker: Thomas Lozito, Assistant Professor, University of Southern California. Lizard Tail Regeneration as an Instructive Model of Enhanced Healing Capabilities in an Adult Amniote.
4:45-5:30PM Perspectives Speaker: Doug Melton, Harvard University. Islet biology and diabetes from a developmental perspective.
5:30-9:00PM Dinner
DAY 3: JULY 25, 2019
8:30-10:00AM PI meeting session 1 and Trainee meeting session 1
10:00-10:30AM Coffee break
10:30AM- 12:00PM PI meeting session 2 and Trainee Lightsheet Imaging of Salamanders Workshop (Institute for Chemical Imaging of Living Systems)