October 1, 2026

New Publication Out

Check out our newewst paper where we present the probing of allosteric mechanisms through a comparative study of the katanin, a microtubule severing protein including a clade 3 AAA domain, and the double-ring ClpB, a protein disaggregase including both a clade 3 and a clade 5 AAA domain.

Check out our newewst paper where we employed molecular dynamics simulations and quantitative analysis combining principal component analysis, clustering, distance distribution analysis, and contact tracing to investigate how natural tubulin CTTs (beta5, beta4b, and beta3) and engineered CTTs (beta5-A+Y, beta5-cterm, beta5-midpoint, and poly-E) influence katanin structure and dynamics in spiral and ring conformations