Publications from IIT-Kharagpur

Coming soon

Some representative publications from Post doc and Ph. D.

1. Melissa L Boby, Daren Fearon, Matteo Ferla, Mihajlo Filep, Lizbé Koekemoer, Matthew C Robinson,  John D Chodera, Alpha A Lee, Nir London, Annette von Delft, Frank von Delft,  COVID Moonshot Consortium‡ (Rambabu N. Reddi, part of the Consortium), Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors, Science, 2024, 382, 6671

2. Ronen Gabizon, #  Barr Tivon, #  Rambabu N. Reddi, Maxime C. M. van den Oetelaar, Peter J. Cossar, Christian Ottmann, Nir London*, A simple method for developing lysine targeted covalent protein reagents, Nat Commun., 2023,  14, 7933. https://doi.org/10.1038/s41467-023-42632-5. IF = 17.2. https://www.nature.com/articles/s41467-023-42632-5

3. Rambabu N. Reddi* Adi Rogel, Ronen Gabizon, Dattatraya G. Rawale, Harish Battu, Shir Marom, Barr Tivon, Neta Gurwicz, Roni Oren, Keren David, Jingjing Liu, Shirly Duberstein, Maxim Itkin, Sergey Malitsky, Haim Barr, Idit Shachar, Ziv Shulman, Nir London,* Sulfamate acetamides as self-immolative electrophiles for covalent ligand directed release chemistry, J. Am. Chem. Soc., 2023, 145, 6, 3346-3360 (as a first and co-corresponding author). https://doi.org/10.1021/jacs.2c08853, IF = 16.38. 

4. Sreenivasmurthy SG, Iyaswamy A, Krishnamoorthi S, Rambabu N. Reddi, Kammala AK, Vasudevan K, Senapati S, Zhu Z, Su C-F, Liu J, Guan X-J, Chua K-K, Cheung K-H, Chen H, Zhang H-J, Zhang Y, Song J-X, Kumar Durairajan SS and Li M, Bromo-protopine, a novel protopine derivative, alleviates tau pathology by activating chaperone-mediated autophagy for Alzheimer’s disease therapy, Front. Mol. Biosci., 2022, 9:1030534. doi: 10.3389/fmolb.2022.1030534. IF = 4.61. 

5. Rambabu N. Reddi, # Adi Rogel,# Efrat Resnick, Ronen Gabizon, Pragati Kishore Prasad, Neta Gurwicz, Haim Barr, Ziv Shulman, Nir London*, Site-Specific Labelling of Endogenous Proteins Using CoLDR Chemistry, J. Am. Chem. Soc., 2021, 143, 48, 20095–20108. https://doi.org/10.1021/jacs.1c06167. IF = 16.38. 

6. Rambabu N Reddi, Efrat Resnick, Adi Rogel, Boddu Venkateswara Rao, Ronen Gabizon, Kim Goldenberg, Neta Gurwicz, Daniel Zaidman, Alexander Plotnikov, Haim Barr, Ziv Shulman, Nir London, Tunable Methacrylamides for Covalent Ligand Directed Release Chemistry, J. Am. Chem. Soc., 2021, 143 (13), 4979-4992. DOI: 10.1021/jacs.0c10644. IF = 16.38. 

7. Angela Mosebarger, Rambabu N. Reddi, Ramkumar Menon and Ananth Kumar Kammala*, Computational Screening of the Natural Product Osthole and Its Derivates for Anti-Inflammatory Activity, Life, 2022, 12, 505. https://doi.org/10.3390/life12040505. IF = 3.25 

8. Alice Douangamath, Daren Fearon, Paul Gehrtz, Tobias Krojer, …(20 authors)… Rambabu N. Reddi, Rachael Skyner, Matthew Snee, Michael J. Waring, Conor Wild, Nir London, Frank von Delft & Martin A. Walsh. Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease Nat Commun, 2020, 11, 5047. https://doi.org/10.1038/s41467-020-18709-w (Names are in alphabetical order). I. F. = 17.2. 

9. Hagit Achdout, Anthony Aimon, Elad Bar-David……….Rambabu N. Reddi…. Daniel Zaidmann, Hadeer Zidane, Nicole Zitzmann (106 authors), COVID Moonshot: Open Science Discovery of SARS-CoV-2 Main Protease Inhibitors by Combining Crowdsourcing, High-Throughput Experiments, Computational Simulations, and Machine Learning, DOI: https://doi.org/10.1101/2020.10.29.339317 

10. Siva Sundara Kumar Durairajan, Sonu Kumar Yadav‡, Reshma Ir‡, Rajesh Jeewon, Mukesh Doble, Kevin D. Hyde, Ilango Kaliappan, Ravindrian Jeyaraman, Rambabu N. Reddi, Jayalakshmi Krishnan, Min Li, A Mechanistic Review on Medicinal Mushrooms-Derived Bioactive Compounds: Potential Mycotherapy Candidates for Alleviating Neurological Disorders, Planta Med., 2020; 86(16), 1161-1175. DOI: 10.1055/a11774834. I. F. = 3.35 

11. D. S. S. Kumar*  Rambabu N. Reddi, Sravan Gopalakrishnan Shetty  Ashok Iyaswamy  Ananth Kumar Kammella  Senthil Kumar Krishnamoorthi  Hongjie Zhang  Min Li, Bromo‐protopine, a novel derivative of protopine with improved bioavailability and bioactivity, degrades tau aggregation through modulation of hdac6‐hsp90 chaperonic activity and improves memory via stimulation of the ras‐grf1/erk pathway. Alzheimer's and Dementia 2017, 13 (7), 1575-1576 (conference proceedings). 

For a full list of publications, please see https://scholar.google.com.hk/citations?view_op=list_works&hl=en&hl=en&user=qBIuCfIAAAAJ&sortby=pubdate