Check this educational video that explains the main research area
invideo-ai-1080 Next-Gen Human Models_ Organoids & Organ 2025-04-25.mp4
My research focuses on the development of advanced in vitro models using human iPS cells for regenerative medicine applications. These models aim to recapitulate human organ physiology and inter-organ communication, which is essential for understanding disease mechanisms and improving drug testing accuracy.
I am particularly interested in the development of multi-lineage organoids and their integration with microfluidic devices to create functional organs-on-a-chip. These models will serve as platforms for drug discovery, toxicity testing, and disease modeling.
Illustration by Izumi Mindy Takamiya (CC BY 4.0) KYOTO UNIVERSITY
Cornea-on-a-Chip for Ophthalmic Drug Testing:
We have developed a microfluidic device for the human cornea, which is being used for testing ophthalmic drug formulations and studying corneal diseases.
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3D bioprinter skeltal muscles cells
Skeletal Muscle-on-a-Chip for agel-related disease modeling:
This project aims to create a muscle tissue using 3D bioprinting and microfluidic devices to simulate age-related muscle degeneration. This platform will allow us to study diseases such as sarcopenia and test potential therapeutic compounds.
Multi-Lineage Organoids for Drug Screening:
We are developing multi-lineage human iPSC-derived organoids that integrate retinal, neural, and muscle cells. These models will be used to investigate disease mechanisms and assess drug efficacy in a more physiologically relevant context.