RNO-AI 2019 is the first comprehensive MICCAI workshop on Radiomics and Radiogenomics in Neuro-oncology using AI. The aim of RNO-AI is to bring together the growing number of researchers in the field given the significant amount of effort in the development of tools that can automate the analysis and synthesis of neuro-oncologic imaging. The main purpose of the workshop is to provide a stimulating environment for an in-depth discussion of important recent developments among experts in the field that enables future research impact in the field.